Substrates for peptidase M9E.004: membrane Pro-Xaa carboxypeptidase

Summary Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Ala-Ala-Ala-Ala Ala-Ala-Ala+Ala N - Ala Ala Ala Ala - - - Hiraoka, 2004
angiotensin-2 P01019 34-41 Asp-Arg-Val-Tyr-Ile-His-Pro+Phe N Tyr Ile His Pro Phe - - - Hiraoka, 2004 16515
enterostatin Ala-Pro-Gly-Pro+Arg P Ala Pro Gly Pro Arg - - - Hiraoka, 2004
enterostatin Val-Pro-Asp-Pro+Arg N Val Pro Asp Pro Arg - - - Hiraoka, 2004
Pro-Ala Pro+Ala N - - - Pro Ala - - - Hiraoka, 2004
Pro-Gly Pro+Gly N - - - Pro Gly - - - Hiraoka, 2004
Pro-Ile Pro+Ile N - - - Pro Ile - - - Hiraoka, 2004
Pro-Met Pro+Met N - - - Pro Met - - - Hiraoka, 2004
Pro-Phe Pro+Phe N - - - Pro Phe - - - Hiraoka, 2004
Pro-Thr Pro+Thr N - - - Pro Thr - - - Hiraoka, 2004
Val-Ala-Ala-Phe Val-Ala-Ala+Phe N - Val Ala Ala Phe - - - Hiraoka, 2004
Z-Ala-Met Z-Ala+Met S - - Z Ala Met - - - Hiraoka, 2004
Z-Ala-Phe Z-Ala+Phe S - - Z Ala Phe - - - Hiraoka, 2004
Z-Ala-Tyr Z-Ala+Tyr S - - Z Ala Tyr - - - Hiraoka, 2004
Z-Gly-Phe Z-Gly+Phe S - - Z Gly Phe - - - Hiraoka, 2004
Z-Gly-Pro-Ala Z-Gly-Pro+Ala S - Z Gly Pro Ala - - - Hiraoka, 2004
Z-Gly-Tyr Z-Gly+Tyr S - - Z Gly Tyr - - - Hiraoka, 2004
Z-Pro-Ala Z-Pro+Ala S - - Z Pro Ala - - - Hiraoka, 2004
Z-Pro-Met Z-Pro+Met S - - Z Pro Met - - - Hiraoka, 2004
Z-Pro-Phe Z-Pro+Phe S - - Z Pro Phe - - - Hiraoka, 2004