$VAR1 = undef;

Summary for peptidase M9E.004: membrane Pro-Xaa carboxypeptidase

Names
MEROPS Name	membrane Pro-Xaa carboxypeptidase
Other names	carboxypeptidase P, microsomal prolyl carboxypeptidase

MEROPS Classification
Classification	Clan (unassigned) >> Subclan (unassigned) >> Family (unassigned) >> Subfamily (unassigned) >> M9E.004
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Metallo
NC-IUBMB	Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.17 (Metallocarboxypeptidases) >> Peptidase 3.4.17.16
Enzymology	BRENDA database
Proteolytic events	CutDB database (1 cleavage)
Physiology	Probable role in final stage of hydrolysis of proline-containing peptides.
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/-/Pagfa/-/-/- (based on 20 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'
Gly	0	0	2	2	1
Pro	0	2	0	13	0
Ala	1	1	2	5	4
Val	1	1	0	0	0
Leu	0	0	0	0	0
Ile	0	1	0	0	1
Met	0	0	0	0	3
Phe	0	0	0	0	6
Tyr	1	0	0	0	2
Trp	0	0	0	0	0
Ser	0	0	0	0	0
Thr	0	0	0	0	1
Cys	0	0	0	0	0
Asn	0	0	0	0	0
Gln	0	0	0	0	0
Asp	0	0	1	0	0
Glu	0	0	0	0	0
Lys	0	0	0	0	0
Arg	0	0	0	0	2
His	0	0	1	0	0