Substrates for peptidase M20.006: carnosine dipeptidase I

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Ala-Ala Ala+Ala N - - - Ala Ala - - - Jackson, 2004
Ala-His Ala+His N - - - Ala His - - - Jackson, 2004
Ala-Leu Ala+Leu N - - - Ala Leu - - - Jackson, 2004
Ala-Tyr Ala+Tyr N - - - Ala Tyr - - - Jackson, 2004
anserine beta-Ala+1-methyl-His P - - - Ala His - - - Jackson, 2004
beta-Ala-Ala beta-Ala+Ala N - - - Ala Ala - - - Jackson, 2004
beta-Ala-Phe beta-Ala+Phe N - - - Ala Phe - - - Jackson, 2004
carnosine beta-Ala+His N - - - Ala His - - - Jackson, 2004
Gly-Gly Gly+Gly N - - - Gly Gly - - - Jackson, 2004
Gly-His Gly+His N - - - Gly His - - - Jackson, 2004
Gly-His-Gly Gly+His-Gly N - - - Gly His Gly - - Jackson, 2004
Gly-His-Lys Gly+His-Lys N - - - Gly His Lys - - Jackson, 2004
Gly-Leu Gly+Leu N - - - Gly Leu - - - Jackson, 2004
homocarnosine gamma-aminobutyryl+His N - - - GAB His - - - Jackson, 2004
Leu-Leu Leu+Leu N - - - Leu Leu - - - Jackson, 2004
Phe-Ala Phe+Ala N - - - Phe Ala - - - Jackson, 2004
Ser-His Ser+His N - - - Ser His - - - Jackson, 2004