Substrates for peptidase C64.004: trabid peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
diubiquitin	P0CG47	1-76	peptide-Gly76+Lys63-peptide	P		Leu	Arg	Gly	Gly	Lys	Glu	Ser	Thr	Mevissen et al., 2013
diubiquitin	P0CG47	1-76	peptide-Gly76+Lys29-peptide	P		Leu	Arg	Gly	Gly	Lys	Ile	Gln	Asp	Mevissen et al., 2013
diubiquitin	P0CG47	1-76	peptide-Gly76+Lys33-peptide	P		Leu	Arg	Gly	Gly	Lys	Glu	Gly	Ile	Mevissen et al., 2013
Lys29-linked diubiquitin	P0CG47/P0CG47	1-76	Peptide-Gly76+Lys29-Peptide	P	AB	Leu	Arg	Gly	Gly	Lys	Ile	Gln	Asp	Licchesi et al., 2011
Lys33-linked diubiquitin	P0CG47/P0CG47	1-76	Peptide-Gly76+Lys33-Peptide	P	AB	Leu	Arg	Gly	Gly	Lys	Glu	Gly	Ile	Licchesi et al., 2011
polyubiquitin	P0CG47/P0CG47	1-76	peptide-Gly76+Lys63-peptide	P		Leu	Arg	Gly	Gly	Lys	Glu	Ser	Thr	Tran et al., 2008
polyubiquitinated adenomatous polyposis coli protein	P0CG47P25054	1-76	peptide-Gly76+Lys-peptide	P		Leu	Arg	Gly	Gly	Lys	Xaa	Xaa	Xaa	Tran et al., 2008
ubiquitinated coronin-7	P0CG47/P57737	1-76	peptide-Gly76+Lys33-peptide	P		Leu	Arg	Gly	Gly	Lys	Glu	Gly	Ile	Yuan et al., 2014