Literature for peptidase C64.004: trabid peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, I Inhibitor, K Knockout. To select only the references relevant to a single topic, click the link above. See explanation.)

    2023
  1. Chen,Y.H., Chen,H.H., Wang,W.J., Chen,H.Y., Huang,W.S., Kao,C.H., Lee,S.R., Yeat,N.Y., Yan,R.L., Chan,S.J., Wu,K.P. and Chen,R.H.
    TRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation
    Nat Commun14, 3050-3050. PubMed  Europe PubMed DOI
  2. Huang,S., Zhang,Q., Zhao,M., Wang,X., Zhang,Y., Gan,B. and Zhang,P.
    The deubiquitinase ZRANB1 is an E3 ubiquitin ligase for SLC7A11 and regulates ferroptotic resistance
    J Cell Biol222, PubMed  Europe PubMed DOI
  3. Kloet,M.S. and van der Heden van Noort
    Synthetic Diubiquitin Fluorogenic Substrates to Study DUBs
    Methods Mol Biol2591, 17-24. PubMed  Europe PubMed DOI
  4. Mei,Y., Hang,Q., Teng,H., Yao,F., Chen,M.K., Hung,M.C., Sun,Y. and Ma,L.
    ZRANB1 is an NBS1 deubiquitinase and a potential target to overcome radioresistance and PARP inhibitor resistance in triple-negative breast cancer
    Genes Dis10, 1739-1742. PubMed  Europe PubMed DOI
  5. 2022
  6. Tamura,A., Ito,G., Matsuda,H., Nibe-Shirakihara,Y., Hiraoka,Y., Kitagawa,S., Hiraguri,Y., Nagata,S., Aonuma,E., Otsubo,K., Nemoto,Y., Nagaishi,T., Watanabe,M., Okamoto,R. and Oshima,S.
    Zranb1-mutant mice display abnormal colonic mucus production and exacerbation of DSS-induced colitis
    Biochem Biophys Res Commun628, 147-154. PubMed  Europe PubMed DOI
  7. 2021
  8. Chen,Y.H., Huang,T.Y., Lin,Y.T., Lin,S.Y., Li,W.H., Hsiao,H.J., Yan,R.L., Tang,H.W., Shen,Z.Q., Chen,G.C., Wu,K.P., Tsai,T.F. and Chen,R.H.
    VPS34 K29/K48 branched ubiquitination governed by UBE3C and TRABID regulates autophagy, proteostasis and liver metabolism
    Nat Commun12, 1322-1322. PubMed  Europe PubMed DOI
  9. Li,Q., Chao,Q., Liu,Y., Fang,J., Xie,J., Zhen,J., Ding,Y., Fu,B., Ke,Y., Xiao,F., Wu,H., Huang,Z., Hao,H. and Huang,D.
    Deubiquitinase ZRANB1 drives hepatocellular carcinoma progression through SP1-LOXL2 axis
    Am J Cancer Res11, 4807-4825. PubMed  Europe PubMed  K
  10. 2020
  11. Harris,L.D., Le Pen,J., Scholz,N., Mieszczanek,J., Vaughan,N., Davis,S., Berridge,G., Kessler,B., Bienz,M. and Licchesi,J.D.F.
    The deubiquitinase TRABID stabilises the K29/K48-specific E3 ubiquitin ligase HECTD1
    J Biol Chem PubMed  Europe PubMed DOI  K
  12. 2019
  13. Zhu,Y., Qu,C., Hong,X., Jia,Y., Lin,M., Luo,Y., Lin,F., Xie,X., Xie,X., Huang,J., Wu,Q., Qiu,X., Piao,D., Xing,Y., Yu,T., Lu,Y., Huang,Q., Yu,C., Jin,J. and Zhang,Z.
    Trabid inhibits hepatocellular carcinoma growth and metastasis by cleaving RNF8-induced K63 ubiquitination of Twist1
    Cell Death Differ26, 306-320. PubMed  Europe PubMed DOI
  14. 2018
  15. Zhang,P., Xiao,Z., Wang,S., Zhang,M., Wei,Y., Hang,Q., Kim,J., Yao,F., Rodriguez-Aguayo,C., Ton,B.N., Lee,M., Wang,Y., Zhou,Z., Zeng,L., Hu,X., Lawhon,S.E., Siverly,A.N., Su,X., Li,J., Xie,X., Cheng,X., Liu,L.C., Chang,H.W., Chiang,S.F., Lopez-Berestein,G., Sood,A.K., Chen,J., You,M.J., Sun,S.C., Liang,H., Huang,Y., Yang,X., Sun,D., Sun,Y., Hung,M.C. and Ma,L.
    ZRANB1 is an EZH2 deubiquitinase and a potential therapeutic target in breast cancer
    Cell Rep23, 823-837. PubMed  Europe PubMed DOI
  16. 2016
  17. Jin,J., Xie,X., Xiao,Y., Hu,H., Zou,Q., Cheng,X. and Sun,S.C.
    Epigenetic regulation of the expression of Il12 and Il23 and autoimmune inflammation by the deubiquitinase Trabid
    Nat Immunol17, 259-268. PubMed  Europe PubMed DOI
  18. 2015
  19. Kristariyanto,Y.A., Abdul Rehman,S.A., Campbell,D.G., Morrice,N.A., Johnson,C., Toth,R. and Kulathu,Y.
    K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of K29 polyubiquitin
    Mol Cell58, 83-94. PubMed  Europe PubMed DOI
  20. Michel,M.A., Elliott,P.R., Swatek,K.N., Simicek,M., Pruneda,J.N., Wagstaff,J.L., Freund,S.M. and Komander,D.
    Assembly and specific recognition of K29- and K33-linked polyubiquitin
    Mol Cell58, 95-109. PubMed  Europe PubMed DOI  S
  21. 2014
  22. Fernando,M.D., Kounatidis,I. and Ligoxygakis,P.
    Loss of Trabid, a new negative regulator of the Drosophila immune-deficiency pathway at the level of TAK1, reduces life span
    PLoS Genet10, e1004117-e1004117. PubMed  Europe PubMed DOI
  23. Yuan,W.C., Lee,Y.R., Lin,S.Y., Chang,L.Y., Tan,Y.P., Hung,C.C., Kuo,J.C., Liu,C.H., Lin,M.Y., Xu,M., Chen,Z.J. and Chen,R.H.
    K33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein Trafficking
    Mol Cell54, 586-600. PubMed  Europe PubMed DOI
  24. 2012
  25. Kessler,B.M.
    Otubains
    [ISSN:978-0-12-407743-0]3, 2113-2120. DOI
  26. Licchesi,J.D., Mieszczanek,J., Mevissen,T.E., Rutherford,T.J., Akutsu,M., Virdee,S., Oualid,F.E., Chin,J.W., Ovaa,H., Bienz,M. and Komander,D.
    An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains
    Nat Struct Mol Biol19, 62-71. PubMed  Europe PubMed DOI  S
  27. Shi,T., Bao,J., Wang,N.X., Zheng,J. and Wu,D.
    Identification of small molecule TRABID deubiquitinase inhibitors by computation-based virtual screen
    BMC Chem Biol12, 4-4. PubMed  Europe PubMed DOI  I
  28. 2010
  29. Virdee,S., Ye,Y., Nguyen,D.P., Komander,D. and Chin,J.W.
    Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase
    Nat Chem Biol6, 750-757. PubMed  Europe PubMed DOI
  30. 2008
  31. Tran,H., Hamada,F., Schwarz-Romond,T. and Bienz,M.
    Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains
    Genes Dev22, 528-542. PubMed  Europe PubMed DOI
  32. 2001
  33. [YEAR:1-8-2001]Evans,P.C., Taylor,E.R., Coadwell,J., Heyninck,K., Beyaert,R. and Kilshaw,P.J.
    Isolation and characterization of two novel A20-like proteins
    Biochem J357, 617-623. PubMed  Europe PubMed DOI