Substrates for peptidase C54.003: autophagin-1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
Ac-Asn-Thr-Phe-Gly-ACC			Ac-Asn-Thr-Phe-Gly+ACC	S		Asn	Thr	Phe	Gly	ACC	-	-	-	Shu et al., 2010
Ac-Asn-Thr-Phe-Gly-AFC			Ac-Asn-Thr-Phe-Gly+AFC	S		Asn	Thr	Phe	Gly	AFC	-	-	-	Shu et al., 2010
Ac-Glu-Thr-Phe-Gly-ACC			Ac-Glu-Thr-Phe-Gly+ACC	S		Glu	Thr	Phe	Gly	ACC	-	-	-	Shu et al., 2010
Ac-Glu-Thr-Phe-Gly-AFC			Ac-Glu-Thr-Phe-Gly+AFC	S		Glu	Thr	Phe	Gly	AFC	-	-	-	Shu et al., 2010
Ac-Gly-Leu-Phe-Gly-ACC			Ac-Gly-Leu-Phe-Gly+ACC	S		Ser	Leu	Phe	Gly	ACC	-	-	-	Shu et al., 2010
Ac-Gly-Thr-Phe-Gly-AFC			Ac-Gly-Thr-Phe-Gly+AFC	S		Gly	Thr	Phe	Gly	AFC	-	-	-	Shu et al., 2010
Ac-Gly-Val-Phe-Gly-ACC			Ac-Gly-Val-Phe-Gly+ACC	S		Gly	Val	Phe	Gly	ACC	-	-	-	Shu et al., 2010
Ac-Ser-Leu-Phe-Gly-ACC			Ac-Ser-Leu-Phe-Gly+ACC	S		Gly	Leu	Phe	Gly	ACC	-	-	-	Shu et al., 2010
Ac-Ser-Thr-Phe-Gly-AFC			Ac-Ser-Thr-Phe-Gly+AFC	S		Ser	Thr	Phe	Gly	AFC	-	-	-	Shu et al., 2010
Ac-Ser-Val-Phe-Gly-ACC			Ac-Ser-Val-Phe-Gly+ACC	S		Ser	Val	Phe	Gly	ACC	-	-	-	Shu et al., 2010
gamma-aminobutyric acid receptor associated protein	O95166	1-117	peptide-Gly116+Leu-peptide	P		Ser	Val	Tyr	Gly	Leu	-	-	-	Tanida et al., 2004
Gamma-aminobutyric acid receptor-associated protein-like 1	Q9H0R8	1-117	Peptide-Gly116+Lys	P	CS	Ser	Val	Tyr	Gly	Lys	-	-	-	Li et al., 2011
gamma-aminobutyric acid receptor-associated protein-like 2	P60520	1-117	peptide-Gly116+Phe-peptide	P		Asn	Thr	Phe	Gly	Phe	-	-	-	Tanida et al., 2004
microtubule-associated proteins 1A/1B light chain 3B precursor	Q9GZQ8	2-125	peptide-Gly119+Met-peptide	P		Glu	Thr	Phe	Gly	Met	Lys	Leu	Ser	Tanida et al., 2004	18058
Microtubule-associated proteins 1A/1B light chain 3C	Q9BXW4	1-147	Pep-Gly126+Cys-Peptide	P	AB	Glu	Thr	Phe	Gly	Cys	Leu	Glu	Ser	Shu et al., 2010