Substrates for peptidase C48.003: SENP3 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
PolySUMO2/SUMO3	P61956		peptide-Gly93+Lys11-peptide	N	Gln	Thr	Gly	Gly	Lys	Thr	Glu	Asn	Mendes et al., 2015
Ran GTPase-activating protein 1–polySUMO-2/SUMO-3 conjugate	P46060		peptide-Gly93+Lys8-peptide	N	Gln	Thr	Gly	Gly	Lys	Leu	Ala	Glu	Mendes et al., 2015
small ubiquitin-related modifier 2 precursor	P61956	1-93	peptide-Gly93+Lys524-peptide	P	Gln	Thr	Gly	Gly	Lys	Ser	Glu	Asp	Nishida et al., 2000
SUMO-1/RanGAP1 conjugate	P63165	1-97	peptide-Gly97+Lys524-peptide	P	Gln	Thr	Gly	Gly	Lys	Ser	Glu	Asp	Nishida et al., 2000
SUMO2 sumoylated histone acetyltransferase p300	P61956/Q09472	1-93	peptide-Gly93+Lys1020-peptide	P	Gln	Thr	Gly	Gly	Lys	Thr	Glu	Ile	Huang et al., 2009
SUMO2 sumoylated histone acetyltransferase p300	P61956/Q09472	1-93	peptide-Gly93+Lys1024-peptide	P	Gln	Thr	Gly	Gly	Lys	Glu	Glu	Glu	Huang et al., 2009
SUMO3 sumoylated histone acetyltransferase p300	P55854/Q09472	1-92	peptide-Gly93+Lys1020-peptide	P	Gln	Thr	Gly	Gly	Lys	Thr	Glu	Ile	Huang et al., 2009
SUMO3 sumoylated histone acetyltransferase p300	P55854/Q09472	1-92	peptide-Gly93+Lys1024-peptide	P	Gln	Thr	Gly	Gly	Lys	Glu	Glu	Glu	Huang et al., 2009