Substrates for peptidase C47.004: staphopain C

Summary Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Abz-Ile-Ala-Lys-Asp-ANB-NH2			Abz-Ile-Ala-Lys-Asp+ANB-NH2	S	MS	Ile	Ala	Lys	Asp	ANB	NH2	-	-	Kalinska et al., 2012
alpha-1-antichymotrypsin	P01011	24-423	peptide-Leu383+Ser-peptide	N	NT	Ile	Thr	Leu	Leu	Ser	Ala	Leu	Val	Wladyka et al., 2011
alpha-1-antichymotrypsin	P01011	24-423	peptide-Ser384+Ala-peptide	N	NT	Thr	Leu	Leu	Ser	Ala	Leu	Val	Glu	Wladyka et al., 2011
alpha-1-antichymotrypsin (Leu382Ala mutant)	P01011	24-423	peptide-Leu386+Val-peptide	N	NT	Leu	Ser	Ala	Leu	Val	Glu	Thr	Arg	Wladyka et al., 2011
alpha-1-antichymotrypsin (Leu383Ala mutant)	P01011	24-423	peptide-Leu386+Val-peptide	N	NT	Leu	Ser	Ala	Leu	Val	Glu	Thr	Arg	Wladyka et al., 2011
alpha-1-antitrypsin	P01009	25-418	peptide-Glu378+Ala-peptide	N	NT	Met	Phe	Leu	Glu	Ala	Ile	Pro	Met	Wladyka et al., 2011
antithrombin-III	P01008	33-464	peptide-Ile422+Ala-peptide	N	NT	Ala	Val	Val	Ile	Ala	Gly	Arg	Ser	Wladyka et al., 2011
antithrombin-III	P01008	33-464	peptide-Ala423+Gly-peptide	N	NT	Val	Val	Ile	Ala	Gly	Arg	Ser	Leu	Wladyka et al., 2011
MBP-linker-GFP fusion			Peptide-Gly+Ala-Peptide	N	MS	Leu	Val	Phe	Gly	Ala	Met	Cpe	-	Kalinska et al., 2012
Suc-Gly-Phe-Gly-NHPhNO2			Suc-Gly-Phe-Gly+NHPhNO2	S		Suc	Gly	Phe	Gly	NAN	-	-	-	Wladyka et al., 2011