Substrates for peptidase C04.001: nuclear-inclusion-a peptidase (plum pox virus)

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
Ac-Ala-Ala-Val-Tyr-His-Gln-Ala-Ala-NH2			Ac-Ala-Ala-Val-Tyr-His-Gln+Ala-Ala-NH2	S		Val	Tyr	His	Gln	Ala	Ala	NH2	-	Han et al., 2004
Ac-Glu-Pro-Thr-Val-Tyr-His-Gln-Thr-Leu-NH2			Ac-Glu-Pro-Thr-Val-Tyr-His-Gln+Thr-Leu-NH2	S		Val	Tyr	His	Gln	Thr	Leu	NH2	-	Han et al., 2004
amyloid beta A4 protein	P05067	672-770	peptide-Gln686+Lys-peptide	N		Val	His	His	Gln	Lys	Leu	Val	Phe	Han et al., 2010
cellulose synthase	M5VVE4	1-1096	peptide-Gln248+Gly-peptide	P	NT	Val	Lys	His	Gln	Gly	Gly	Asn	Asp	Xiao et al., 2021
dimethylaminonaphthalenesulfonyl-Pro-Val-Tyr-His-Gln-Ala-Trp-NH2			dimethylaminonaphthalenesulfonyl-Pro-Val-Tyr-His-Gln+Ala-Trp-NH2	S		Val	Tyr	His	Gln	Ala	Trp	NH2	-
dimethylaminonaphthalenesulfonyl-Pro-Val-Tyr-His-Gln-Trp-NH2			dimethylaminonaphthalenesulfonyl-Pro-Val-Tyr-His-Gln+Trp-NH2	S		Val	Tyr	His	Gln	Trp	NH2	-	-
Genome polyprotein	A0A165KDP5	1-3140	peptide-Gln2810+Ala-peptide	P	NT	Val	Val	His	Gln	Ala	Asp	Glu	Arg	Xiao et al., 2021
Genome polyprotein	P04517	1-3054	peptide-Gln2791+Ser-peptide	P	NT	Leu	Tyr	Phe	Gln	Ser	Gly	Thr	Val	Xiao et al., 2021
GPI-anchored adhesin-like protein	F4JFS3	1-1270	peptide-Gln465+Gly-peptide	P	NT	Val	Arg	His	Gln	Gly	Asn	Ser	Pro	Xiao et al., 2021
lysine ketoglutarate reductase trans-splicing protein (DUF707)	A0A1P8AMP7	1-388	peptide-Gln328+Ser-peptide	P	NT	Val	Val	His	Gln	Ser	Phe	Pro	Ser	Xiao et al., 2021
NH2-Glu-Pro-Thr-Val-Tyr-His-Gln-Thr-Leu-Asn-Glu			NH2-Glu-Pro-Thr-Val-Tyr-His-Gln+Thr-Leu-Asn-Glu	N		Val	Tyr	His	Gln	Thr	Leu	Asn	Glu	Han et al., 2004
NIa protease	P89509	2117-2359	peptide-Ser223+Gly-peptide	P		Ser	Gln	Pro	Ser	Gly	Leu	Phe	Lys	Han et al., 2004	16181
NIa protease	P89509	2117-2359	peptide-Thr207+Ser-peptide	P		Lys	Tyr	Asn	Thr	Ser	Ala	Ile	Ser	Han et al., 2004	16182
o-aminobenzoyl-Ala-Ala-Val-Tyr-His-Gln-Ala-Ala-NHPhNO2			o-aminobenzoyl-Ala-Ala-Val-Tyr-His-Gln+Ala-Ala-NHPhNO2	S		Val	Tyr	His	Gln	Ala	Ala	NAN	-	Han et al., 2004
Pro-Thr-Thr-Glu-Asn-Leu-Tyr-Phe-Gln-Ser-Gly-Thr-Val-Asp-Arg-Arg			Pro-Thr-Thr-Glu-Asn-Leu-Tyr-Phe-Gln+Ser-Gly-Thr-Val-Asp-Arg-Arg	N		Leu	Tyr	Phe	Gln	Ser	Gly	Thr	Val	Han et al., 2004
protein EMSY-LIKE 2	Q9FG29	1-313	peptide-Gln80+Ser-peptide	P	NT	Val	Arg	His	Gln	Ser	Leu	Asp	Val	Xiao et al., 2021
putative F-box/kelch-repeat protein At1g20790	Q9LM75	1-435	peptide-Gln275+Ser-peptide	P	NT	Val	Val	His	Gln	Ser	Leu	Pro	Leu	Xiao et al., 2021
transcription factor PIF7	Q570R7	1-366	peptide-Ala52+Ala-peptide	P	NT	Val	His	Gln	Ala	Ala	Leu	Gln	Gln	Xiao et al., 2021
transcription repressor KAN1	Q93WJ9	1-403	peptide-Gln302+Ser-peptide	P	NT	Val	His	His	Gln	Ser	Ser	Thr	Asp	Xiao et al., 2021
uncharacterized protein	F4IT02	1-328	peptide-Gln82+Thr-peptide	P	NT	Val	Val	His	Gln	Thr	Val	Gly	Ser	Xiao et al., 2021
uncharacterized protein	M5W936	1-657	peptide-Gln126+Ala-peptide	P	NT	Val	Val	His	Gln	Ala	Ser	Val	Met	Xiao et al., 2021