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Substrates for peptidase C01.130: CSCP3 peptidase (Clonorchis-type)

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Cathepsin F W5RUH3 1-308 Peptide-Lys71+Thr-Peptide P NT Glu Glu Phe Lys Thr Arg Tyr Leu Sripa et al., 2010
Cathepsin F W5RUH3 1-308 Peptide-Thr95+Met-Peptide P NT Glu Asp Val Thr Met Asp Asn Ser Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Val-Leu3+Ser-Peptide N MS - - Val Leu Ser Pro Ala Asp Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Pro5+Ala-Peptide N MS Val Leu Ser Pro Ala Asp Lys Thr Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Thr9+Asn+Peptide N MS Ala Asp Lys Thr Asn Val Lys Ala Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Ala14+Trp-Peptide N MS Val Lys Ala Ala Trp Gly Lys Val Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Trp15+Gly-Peptide N MS Lys Ala Ala Trp Gly Lys Val Gly Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Glu28+Ala-Peptide N MS Tyr Gly Ala Glu Ala Leu Glu Arg Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Ala29+Leu-Peptide N MS Gly Ala Glu Ala Leu Glu Arg Met Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Pro38+Thr-Peptide N MS Leu Ser Phe Pro Thr Thr Lys Thr Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Thr39+Thr-Peptide N MS Ser Phe Pro Thr Thr Lys Thr Tyr Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Thr40+Lys-Peptide N MS Phe Pro Thr Thr Lys Thr Tyr Phe Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Lys41+Thr-Peptide N MS Pro Thr Thr Lys Thr Tyr Phe Pro Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Gln55+Val-Peptide N MS Gly Ser Ala Gln Val Lys Gly His Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Val56+Lys-Peptide N MS Ser Ala Gln Val Lys Gly His Gly Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Gly58+His-Peptide N MS Gln Val Lys Gly His Gly Lys Lys Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Lys62+Val-Peptide N MS His Gly Lys Lys Val Ala Asp Ala Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Asp65+Ala-Peptide N MS Lys Val Ala Asp Ala Leu Thr Asn Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Val71+Ala-Peptide N MS Thr Asn Ala Val Ala His Val Asp Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Ala72+His-Peptide N MS Asn Ala Val Ala His Val Asp Asp Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Asp74+Asp-Peptide N MS Ala His Val Asp Asp Met Pro Asn Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Asn79+Ala-Peptide N MS Asp Met Pro Asn Ala Leu Ser Ala Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Leu84+Ser-Peptide N MS Leu Ser Ala Leu Ser Asp Leu His Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Leu87+His-Peptide N MS Leu Ser Asp Leu His Ala His Lys Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Asp95+Pro-Peptide N MS Leu Arg Val Asp Pro Val Asn Phe Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Val97+Asn-Peptide N MS Val Asp Pro Val Asn Phe Lys Leu Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Thr109+Leu-Peptide N MS Leu Leu Val Thr Leu Ala Ala His Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Ala111+Ala-Peptide N MS Val Thr Leu Ala Ala His Leu Pro Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Ala112+His-Peptide N MS Thr Leu Ala Ala His Leu Pro Ala Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Pro120+Ala-Peptide N MS Glu Phe Thr Pro Ala Val His Ala Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Val133+Ser-Peptide N MS Leu Ala Ser Val Ser Thr Val Leu Sripa et al., 2010
Hemoglobin subunit alpha P69905 2-142 Peptide-Val136+Leu-Peptide N MS Val Ser Thr Val Leu Thr Ser Lys Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Glu7+Glu-Peptide N MS Leu Thr Pro Glu Glu Lys Ser Ala Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Lys18+Val-Peptide N MS Leu Trp Gly Lys Val Asn Val Asp Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Gly26+Glu-Peptide N MS Glu Val Gly Gly Glu Ala Leu Gly Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Phe43+Glu-Peptide N MS Gln Arg Phe Phe Glu Ser Phe Gly Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Glu44+Ser-Peptide N MS Arg Phe Phe Glu Ser Phe Gly Asp Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Ser45+Phe-Peptide N MS Phe Phe Glu Ser Phe Gly Asp Leu Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Phe46+Gly-Peptide N MS Phe Glu Ser Phe Gly Asp Leu Ser Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Asp53+Ala-Peptide N MS Ser Thr Pro Asp Ala Val Met Gly Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Pro50+Lys-Peptide N MS Met Gly Asn Pro Lys Val Lys Ala Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Phe72+Ser-Peptide N MS Leu Gly Ala Phe Ser Asp Gly Leu Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Gly75+Leu-Peptide N MS Phe Ser Asp Gly Leu Ala His Leu Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Leu76+Ala-Peptide N MS Ser Asp Gly Leu Ala His Leu Asp Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Ala77+His-Peptide N MS Asp Gly Leu Ala His Leu Asp Asn Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Gly84+Thr-Peptide N MS Asn Leu Lys Gly Thr Phe Ala Thr Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Glu91+Leu-Peptide N MS Thr Leu Ser Glu Leu His Cys Asp Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Cys94+Asp-Peptide N MS Glu Leu His Cys Asp Lys Leu His Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Val99+Asp-Peptide N MS Lys Leu His Val Asp Pro Glu Asn Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Gly108+Asn-Peptide N MS Arg Leu Leu Gly Asn Val Leu Val Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-His117+His-Peptide N MS Val Leu Ala His His Phe Gly Lys Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Pro125+Pro-Peptide N MS Glu Phe Thr Pro Pro Val Gln Ala Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Gln132+Lys-Peptide N MS Ala Ala Tyr Gln Lys Val Val Ala Sripa et al., 2010
Hemoglobin subunit beta P68871 2-147 Peptide-Val138+Ala-peptide N MS Val Ala Gly Val Ala Asn Ala Leu Sripa et al., 2010
Z-Arg-Arg-NHMec Z-Arg-Arg+NHMec S - Z Arg Arg AMC - - - Park et al., 2001
Z-Phe-Arg-NHMec Z-Phe-Arg+NHMec S - Z Phe Arg AMC - - - Park et al., 2001

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