Substrates for peptidase A01.084: yolk cathepsin (Boophilus sp.)

Summary Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
hemoglobin subunit alpha	P01966	2-142	peptide-Leu30+Glu-peptide	N	Ala	Glu	Ala	Leu	Glu	Arg	Met	Phe	Nascimento-Silva et al., 2008
hemoglobin subunit alpha	P01966	2-142	peptide-Met33+Phe-peptide	N	Leu	Glu	Arg	Met	Phe	Leu	Ser	Phe	Nascimento-Silva et al., 2008
hemoglobin subunit alpha	P01966	2-142	peptide-Leu87+His-peptide	N	Leu	Ser	Asp	Leu	His	Ala	His	Lys	Nascimento-Silva et al., 2008
hemoglobin subunit alpha	P01966	2-142	peptide-Phe99+Lys-peptide	N	Pro	Val	Asn	Phe	Lys	Leu	Leu	Ser	Nascimento-Silva et al., 2008
hemoglobin subunit alpha	P01966	2-142	peptide-Leu106+Leu-peptide	N	Ser	His	Ser	Leu	Leu	Val	Thr	Leu	Nascimento-Silva et al., 2008
hemoglobin subunit alpha	P01966	2-142	peptide-Leu107+Val-peptide	N	His	Ser	Leu	Leu	Val	Thr	Leu	Ala	Nascimento-Silva et al., 2008
hemoglobin subunit alpha	P01966	2-142	peptide-Leu110+Ala-peptide	N	Leu	Val	Thr	Leu	Ala	Ser	His	Leu	Nascimento-Silva et al., 2008
hemoglobin subunit alpha	P01966	2-142	peptide-Phe129+Leu-peptide	N	Leu	Asp	Lys	Phe	Leu	Ala	Asn	Val	Nascimento-Silva et al., 2008
hemoglobin subunit alpha	P01966	2-142	peptide-Asn132+Val-peptide	N	Phe	Leu	Ala	Asn	Val	Ser	Thr	Val	Nascimento-Silva et al., 2008
hemoglobin subunit alpha	P01966	2-142	peptide-Leu137+Thr-peptide	N	Ser	Thr	Val	Leu	Thr	Ser	Lys	Tyr	Nascimento-Silva et al., 2008
hemoglobin subunit beta	P02070	1-145	peptide-Phe13+Trp-peptide	N	Val	Thr	Ala	Phe	Trp	Gly	Lys	Val	Nascimento-Silva et al., 2008
hemoglobin subunit beta	P02070	1-145	peptide-Leu30+Leu-peptide	N	Leu	Gly	Arg	Leu	Leu	Val	Val	Tyr	Nascimento-Silva et al., 2008
hemoglobin subunit beta	P02070	1-145	peptide-Leu31+Val-peptide	N	Gly	Arg	Leu	Leu	Val	Val	Tyr	Pro	Nascimento-Silva et al., 2008
hemoglobin subunit beta	P02070	1-145	peptide-Tyr34+Pro-peptide	N	Leu	Val	Val	Tyr	Pro	Trp	Thr	Gln	Nascimento-Silva et al., 2008
hemoglobin subunit beta	P02070	1-145	peptide-Phe40+Phe-peptide	N	Thr	Gln	Arg	Phe	Phe	Glu	Ser	Phe	Nascimento-Silva et al., 2008
hemoglobin subunit beta	P02070	1-145	peptide-Leu113+Ala-peptide	N	Val	Val	Val	Leu	Ala	Arg	Asn	Phe	Nascimento-Silva et al., 2008
hemoglobin subunit beta	P02070	1-145	peptide-Asp128+Phe-peptide	N	Leu	Gln	Ala	Asp	Phe	Gln	Lys	Val	Nascimento-Silva et al., 2008