Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P02070

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
6	cathepsin D	1-145	P	normal turnover		Fruitier et al., 1998
13	cathepsin D	1-145	P	normal turnover		Fruitier et al., 1998
13	yolk cathepsin (Boophilus sp.)	1-145	N	normal turnover		Nascimento-Silva et al., 2008
30	cathepsin D	1-145	P	normal turnover		Fruitier et al., 1998
30	yolk cathepsin (Boophilus sp.)	1-145	N	normal turnover		Nascimento-Silva et al., 2008
31	cathepsin D	1-145	P	normal turnover		Fruitier et al., 1998
31	yolk cathepsin (Boophilus sp.)	1-145	N	normal turnover		Nascimento-Silva et al., 2008
34	yolk cathepsin (Boophilus sp.)	1-145	N	normal turnover		Nascimento-Silva et al., 2008
40	cathepsin D	1-145	P	normal turnover		Fruitier et al., 1998
40	yolk cathepsin (Boophilus sp.)	1-145	N	normal turnover		Nascimento-Silva et al., 2008
44	cathepsin D	1-145	P	normal turnover		Fruitier et al., 1998
53	cathepsin D	1-145	P	normal turnover		Fruitier et al., 1998
113	yolk cathepsin (Boophilus sp.)	1-145	N	normal turnover		Nascimento-Silva et al., 2008
128	yolk cathepsin (Boophilus sp.)	1-145	N	normal turnover		Nascimento-Silva et al., 2008