Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P01966

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-142	P		NT	<%Agarwal et al., 2012[]%>
2	cathepsin D	2-142	P	normal turnover		Fruitier et al., 1998
25	cathepsin D	2-142	P	normal turnover		Fruitier et al., 1998
30	yolk cathepsin (Boophilus sp.)	2-142	N	normal turnover		Nascimento-Silva et al., 2008
33	cathepsin D	2-142	P	normal turnover		Fruitier et al., 1998
33	yolk cathepsin (Boophilus sp.)	2-142	N	normal turnover		Nascimento-Silva et al., 2008
87	yolk cathepsin (Boophilus sp.)	2-142	N	normal turnover		Nascimento-Silva et al., 2008
99	yolk cathepsin (Boophilus sp.)	2-142	N	normal turnover		Nascimento-Silva et al., 2008
106	yolk cathepsin (Boophilus sp.)	2-142	N	normal turnover		Nascimento-Silva et al., 2008
107	yolk cathepsin (Boophilus sp.)	2-142	N	normal turnover		Nascimento-Silva et al., 2008
109	cathepsin D	2-142	P	normal turnover		Fruitier et al., 1998
110	yolk cathepsin (Boophilus sp.)	2-142	N	normal turnover		Nascimento-Silva et al., 2008
129	yolk cathepsin (Boophilus sp.)	2-142	N	normal turnover		Nascimento-Silva et al., 2008
132	yolk cathepsin (Boophilus sp.)	2-142	N	normal turnover		Nascimento-Silva et al., 2008
134	cathepsin D	2-142	P	normal turnover		Fruitier et al., 1998
137	cathepsin D	2-142	P	normal turnover		Fruitier et al., 1998
137	yolk cathepsin (Boophilus sp.)	2-142	N	normal turnover		Nascimento-Silva et al., 2008