Substrates for peptidase A01.019: polyporopepsin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
alpha-S1-casein P02662 16-214 peptide-Lys103+Tyr-peptide N Arg Leu Lys Lys Tyr Lys Val Pro Kobayashi, 2004 15860
alpha-S1-casein P02662 16-214 peptide-Phe23+Phe24-peptide N Leu Leu Arg Phe Phe Val Ala Pro Kobayashi, 2004 15861
beta-casein P02666 16-224 peptide-Leu165+Ser-peptide N Val Leu Ser Leu Ser Gln Ser Lys Kobayashi, 2004 15863
beta-casein P02666 16-224 peptide-Ala189+Phe-peptide N Pro Ile Gln Ala Phe Leu Leu Tyr Kobayashi, 2004 15862
beta-casein P02666 16-224 peptide-Leu192+Tyr-peptide N Ala Phe Leu Leu Tyr Gln Glu Pro Kobayashi, 2004 15864
beta-casein P02666 16-224 peptide-Ser142+Trp-peptide N Leu Leu Gln Ser Trp Met His Gln Kobayashi, 2004 15865
insulin B-chain (oxidized) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu+Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala N Gly Ser His Leu Val Glu Ala Leu Kobayashi, 2004
insulin B-chain (oxidized) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe+Phe-Tyr-Thr-Pro-Lys-Ala N Glu Arg Gly Phe Phe Tyr Thr Pro Kobayashi, 2004
insulin B-chain (oxidized) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala+Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala N Leu Val Glu Ala Leu Tyr Leu Val Kobayashi, 2004
insulin B-chain (oxidized) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr+Pro-Lys-Ala N Phe Phe Tyr Thr Pro Lys Ala - Kobayashi, 2004
kappa-casein P02668 22-190 peptide-Phe105+Met-peptide N His Leu Ser Phe Met Ala Ile Pro Kobayashi, 2004 15870