Substrates for peptidase A01.013: mucorpepsin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Insulin B chain (oxidised) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu+Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala N Val Glu Ala Leu Tyr Leu Val Cya Voynick & Fruton, 1971
Insulin B chain (oxidised) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr+Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala N Glu Ala Leu Tyr Leu Val Cya Gly Voynick & Fruton, 1971
Insulin B chain (oxidised) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe+Phe-Tyr-Thr-Pro-Lys-Ala N Glu Arg Gly Phe Phe Tyr Thr Pro Voynick & Fruton, 1971
Insulin B chain (oxidised) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe+Tyr-Thr-Pro-Lys-Ala N Arg Gly Phe Phe Tyr Thr Pro Lys Voynick & Fruton, 1971
kappa-casein P02668 22-190 peptide-Phe105+Met-peptide N His Leu Ser Phe Met Ala Ile Pro Beppu & Nishiyama, 2004 15831
Leu-Ser-Nph-Nle-Ala-Leu-OMe Leu-Ser-Nph+Nle-Ala-Leu-OMe S - Leu Ser Nph Nle Ala Leu - Beppu & Nishiyama, 2004
Lys-Pro-Ile-Glu-Phe-Nph-Arg-Leu Lys-Pro-Ile-Glu-Phe+Nph-Arg-Leu S Pro Ile Glu Phe Nph Arg Leu - Oda et al., 1992
Mucorpepsin P09177 1-427 Peptide-Ala22+Arg-Peptide P NT Leu Thr Ser Ala Arg Pro Val Ser Hiramatsu et al., 1989
Z-His-NPh-Phe-Ala-OMe Z-His-NPh+Phe-Ala-OMe S - Z His Nph Phe Ala OMe - Voynick & Fruton, 1971