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Literature for peptidase A01.013: mucorpepsin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

(Topics flags: S Structure, A Assay, I Inhibitor, P Specificity, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2019
  1. Soltani,M., Sahingil,D., Gokce,Y. and Hayaloglu,A.A.
    Effect of blends of camel chymosin and microbial rennet (Rhizomucor miehei) on chemical composition, proteolysis and residual coagulant activity in Iranian ultrafiltered white cheese
    J Food Sci Technol (2019) 56, 589-598. PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2018
  2. Stergiou,P.Y., Foukis,A., Gkini,O.A., Barouni,E., Georgoulia,P.S., Kanellaki,M., Koutinas,A.A., Papagianni,M. and Papamichael,E.M.
    Novel FRET-substrates of Rhizomucor pusillus rennin: activity and mechanistic studies
    Food Chem (2018) 245, 926-933. PubMed  Europe PubMed DOI  A
  3. Sun,Q., Chen,F., Geng,F., Luo,Y., Gong,S. and Jiang,Z.
    A novel aspartic protease from Rhizomucor miehei expressed in Pichia pastoris and its application on meat tenderization and preparation of turtle peptides
    Food Chem (2018) 245, 570-577. PubMed  Europe PubMed DOI
    4. 2015
  4. Zhang,J., Sun,Y., Li,Z., Luo,Q., Li,T. and Wang,T.
    Structure-based design of Mucor pusillus pepsin for the improved ratio of clotting activity/proteolytic activity in cheese manufacture
    Protein Pept Lett (2015) 22, 660-667. PubMed  Europe PubMed
    5. 2012
  5. Beppu,T. and Nishiyama,M.
    Mucorpepsin
    [ISSN:978-0-12-407744-7] (2012) 3, 154-156. DOI
  6. Garcia,V., Rovira,S., Teruel,R., Boutoial,K., Rodriguez,J., Roa,I. and Lopez,M.B.
    Effect of vegetable coagulant, microbial coagulant and calf rennet on physicochemical, proteolysis, sensory and texture profiles of fresh goats cheese
    Dairy Sci Technol (2012) 92, 691-707. DOI
    7. 2011
  7. Li,T., Wang,J., Li,Y., Zhang,L., Zheng,L., Li,Z., Yang,Z. and Luo,Q.
    Stucture of the complex between Mucor pusillus pepsin and the key domain of kappa-casein for site-directed mutagenesis: a combined molecular modeling and docking approach
    J Mol Model (2011) 17, 1661-1668. PubMed  Europe PubMed DOI  P
    8. 2006
  8. [YEAR:6-3-2006]Machalinski,C., Pirpignani,M.L., Marino,C., Mantegazza,A. and de Jimenez Bonino,M.B.
    Structural aspects of the Mucor bacilliformis proteinase, a new member of the aspartyl-proteinase family
    J Biotechnol (6-3-2006) 123, 443-452. PubMed  Europe PubMed DOI
    9. 2004
  9. Badasso,M.O., Dhanaraj,V., Wood,S.P., Cooper,J.B. and Blundell,T.L.
    Crystallization and X-ray analysis of the Y75N mutant of Mucor pusillus pepsin complexed with inhibitor
    Acta Crystallogr D Biol Crystallogr (2004) 60, 770-772. PubMed  Europe PubMed DOI  S  I
  10. Beppu,T. and Nishiyama,M.
    Mucorpepsin
    [ISSN:0-12-079610-4] (2004) 2, 111-113.  V
    11. 2001
  11. Aikawa ,J., Park,Y.N., Sugiyama,M., Nishiyama,M., Horinouchi,S. and Beppu,T.
    Replacements of amino acid residues at subsites and their effects on the catalytic properties of Rhizomucor pusillus pepsin, an aspartic proteinase from Rhizomucor pusillus
    J Biochem (2001) 129, 791-794. PubMed  Europe PubMed
    12. 1999
  12. Awad,S., Luthi-Peng,Q.Q. and Puhan,Z.
    Proteolytic activities of Suparen and Rennilase on buffalo, cow, and goat whole casein and beta-casein
    J Agric Food Chem (1999) 47, 3632-3639. PubMed  Europe PubMed DOI
  13. Fernandez-Lahore,H.M., Auday,R.M., Fraile,E.R., Biscoglio de Jimenez Bonino,M., Pirpignani,L., Machalinski,C. and Cascone,O.
    Purification and characterization of an acid proteinase from mesophilic Mucor sp. solid-state cultures
    J Pept Res (1999) 53, 599-605. PubMed  Europe PubMed DOI
  14. Montesino,R., Nimtz,M., Quintero,O., Garcia,R., Falcon,V. and Cremata,J.A.
    Characterization of the oligosaccharides assembled on the Pichia pastoris-expressed recombinant aspartic protease
    Glycobiology (1999) 9, 1037-1043. PubMed  Europe PubMed DOI  E
  15. Yang,J. and Quail,J.W.
    Structure of the Rhizomucor miehei aspartic proteinase complexed with the inhibitor pepstatin A at 2.7 A resolution
    Acta Crystallogr D Biol Crystallogr (1999) 55, 625-630. PubMed  Europe PubMed DOI  S  I
    16. 1998
  16. Harboe,M.K.
    Rhizomucor miehei aspartic proteinases having improved properties
    Adv Exp Med Biol (1998) 436, 293-296. PubMed  Europe PubMed
  17. Murakami,K., Takeuchi,K., Beppu,T. and Horinouchi,S.
    Structure of asparagine-linked oligosaccharides of an aspartic proteinase from the zygomycete fungus Rhizomucor pusillus
    Microbiology (Reading, Engl.) (1998) 144, 1369-1374. PubMed  Europe PubMed
    18. 1997
  18. Park,Y.N., Aikawa,J., Nishiyama,M., Horinouchi,S. and Beppu,T.
    Site-directed mutagenesis of conserved Trp39 in Rhizomucor pusillus pepsin: possible role of Trp39 in maintaining Tyr75 in the correct orientation for maximizing catalytic activity
    J Biochem (1997) 121, 118-121. PubMed  Europe PubMed
  19. Preetha,S. and Boopathy,R.
    Purification and characterization of a milk clotting protease from Rhizomucor miehei
    World J Microbiol Biotechnol (1997) 13, 573-578.
  20. Yang,J., Teplyakov,A. and Quail,J.W.
    Crystal structure of the aspartic proteinase from Rhizomucor miehei at 2.15 A resolution
    J Mol Biol (1997) 268, 449-459. PubMed  Europe PubMed DOI  S
    21. 1996
  21. Park,Y.N., Aikawa,J., Nishiyama,M., Horinouchi,S. and Beppu,T.
    Involvement of a residue at position 75 in the catalytic mechanism of a fungal aspartic proteinase, Rhizomucor pusillus pepsin. Replacement of tyrosine 75 on the flap by asparagine enhances catalytic efficiency
    Protein Eng (1996) 9, 869-875. PubMed  Europe PubMed
    22. 1995
  22. Beppu,T., Park,Y.N., Aikawa,J., Nishiyama,M. and Horinouchi,S.
    Tyrosine 75 on the flap contributes to enhance catalytic efficiency of a fungal aspartic proteinase, Mucor pusillus pepsin
    Adv Exp Med Biol (1995) 362, 501-509. PubMed  Europe PubMed
  23. Jia,Z., Vandonselaar,M., Schneider,P. and Quail,J.W.
    Crystallization and preliminary X-ray structure solution of Rhizomucor miehei aspartic proteinase
    Acta Crystallogr D Biol Crystallogr (1995) 51, 243-244. PubMed  Europe PubMed DOI  S
  24. Park,Y.N., Nishiyama,M., Horinouchi,S. and Beppu,T.
    Site-directed mutagenesis revealed role of subsite residues of Mucor pusillus pepsin in catalytic function
    Adv Exp Med Biol (1995) 362, 559-563. PubMed  Europe PubMed
    25. 1993
  25. Newman,M., Watson,F., Roychowdhury,P., Jones,H., Badasso,M., Cleasby,A., Wood,S.P., Tickle,I.J. and Blundell,T.L.
    X-ray analyses of aspartic proteinases. V. Structure and refinement at 2.0 A resolution of the aspartic proteinase from Mucor pusillus
    J Mol Biol (1993) 230, 260-283. PubMed  Europe PubMed DOI  S
    26. 1992
  26. Areces,L.B., Bonino,M.B., Parry,M.A., Fraile,E.R., Fernandez,H.M. and Cascone,O.
    Purification and characterization of a milk clotting protease from Mucor bacilliformis
    Appl Biochem Biotechnol (1992) 37, 283-294. PubMed  Europe PubMed DOI
    27. 1991
  27. Smith,L.J. and Yada,Y.R.
    Chemical modification of amino groups in Mucor miehei aspartyl proteinase, porcine pepsin, and chymosin. II. Conformational stability
    Agric Biol Chem (1991) 55, 2017-2024. DOI
  28. Smith,L.J., Billings,E.G. and Yada,Y.R.
    Chemical modification of amino groups in Mucor miehei aspartyl proteinase, porcine pepsin, and chymosin. I. Structure and function
    Agric Biol Chem (1991) 55, 2009-2016. DOI
    29. 1989
  29. [YEAR:5-10-1989]Hiramatsu,R., Aikawa,J., Horinouchi,S. and Beppu,T.
    Secretion by yeast of the zymogen form of Mucor rennin, an aspartic proteinase of Mucor pusillus, and its conversion to the mature form
    J Biol Chem (5-10-1989) 264, 16862-16866. PubMed  Europe PubMed  E
    30. 1988
  30. Baudys,M., Foundling,S., Pavlik,M., Blundell,T. and Kostka,V.
    Protein chemical characterization of Mucor pusillus aspartic proteinase. Amino acid sequence homology with the other aspartic proteinases, disulfide bond arrangement and site of carbohydrate attachment
    FEBS Lett (1988) 235, 271-274. PubMed  Europe PubMed DOI
  31. Christensen,T., Woeldike,H., Boel,E., Mortensen,S.B., Hjortshoej,K., Thim,L. and Hansen,M.T.
    High-level expression of recombinant genes in Aspergillus oryzae
    Biotechnology (N Y) (1988) 6, 1419-1422.
    32. 1987
  32. Yamashita,T., Tonouchi,N., Uozumi,T. and Beppu,T.
    Secretion of Mucor rennin, a fungal aspartic protease of Mucor pusillus, by recombinant yeast cells
    Mol Gen Genet (1987) 210, 462-467. PubMed  Europe PubMed DOI
    33. 1986
  33. Tonouchi,N., Shoun,H., Uozumi,T. and Beppu,T.
    Cloning and sequencing of a gene for Mucor rennin, an aspartate protease from Mucor pusillus
    Nucleic Acids Res (1986) 14, 7557-7568. PubMed  Europe PubMed  PMC  EPMC
    34. 1982
  34. Etoh,Y., Shoun,H., Arima,K. and Beppu,T.
    Photo-oxidation of a histidyl residue of milk-clotting acid protease, mucor rennin
    J Biochem (1982) 91, 747-753. PubMed  Europe PubMed
  35. Etoh,Y., Shoun,H., Ogino,T., Fujiwara,S., Arima,K. and Beppu,T.
    Proton magnetic resonance spectroscopy of an essential histidyl residue in a milk-clotting acid protease, Mucor rennin
    J Biochem (1982) 91, 2039-2046. PubMed  Europe PubMed
    36. 1979
  36. Etoh,Y., Shoun,H., Beppu,T. and Arima,K.
    Physicochemical and immunochemical studies on similarities of acid proteases Mucor pusillus rennin and Mucor miehei rennin
    Agric Biol Chem (1979) 43, 209-215.
    37. 1976
  37. Takahashi,K., Chang,W.J. and Arima,K.
    The structure and function of acid proteases. IV. Inactivation of the acid protease from Mucor pusillus by acid protease-specific inhibitors
    J Biochem (1976) 80, 61-67. PubMed  Europe PubMed  I
    38. 1973
  38. Morihara,K. and Oka,T.
    Comparative specificity of microbial acid proteinases for synthetic peptides. III. Relationship with their trypsinogen activating ability
    Arch Biochem Biophys (1973) 157, 561-572. PubMed  Europe PubMed  P
  39. Oka,T., Ishino,K., Tsuzuki,H., Morihara,K. and Arima,K.
    On the specificity of a rennin-like enzyme from Mucor pusillus
    Agric Biol Chem (1973) 37, 1177-1184.  P
    40. 1972
  40. Sternberg,M.
    Bond specificity, active site and milk clotting mechanism of the Mucor miehei protease
    Biochim Biophys Acta (1972) 285, 383-392. PubMed  Europe PubMed
    41. 1971
  41. Sternberg,M.Z.
    Crystalline milk-clotting protease from Mucor miehei and some of its properties
    J Dairy Sci (1971) 54, 150-167.
  42. Voynick,I.M. and Fruton,J.S.
    The comparative specificity of acid proteinases
    Proc Natl Acad Sci U S A (1971) 68, 257-259. PubMed  Europe PubMed  PMC  EPMC  P
    43. 1970
  43. Arima,K., Yu,J. and Iwasaki,S.
    Milk-clotting enzyme from Mucor pusillus var. lindt
    Methods Enzymol (1970) 19, 446-459. DOI  V
  44. Ottesen,M. and Rickert,W.
    The acid protease of Mucor miehei
    Methods Enzymol (1970) 19, 459-460.  V
    45. 1969
  45. Yu,J., Tamura,G. and Arima,K.
    Milk clotting enzyme from microorganisms. VI. Properties of crystalline milk-clotting enzyme (mucor rennin) isolated from Mucor pusillus var. lindt
    BBA - Enzymology (1969) 171, 138-144. PubMed  Europe PubMed
    46. 1968
  46. Somkuti,G.A. and Babel,F.J.
    Purification and properties of Mucor pusillus acid protease
    J Bacteriol (1968) 95, 1407-1414. PubMed  Europe PubMed  PMC  EPMC
    47. 1967
  47. Iwasaki,S., Tamura,G. and Arima,K.
    Milk clotting enzyme from microorganisms. Part II. The enzyme production and the properties of crude enzyme
    Agric Biol Chem (1967) 31, 546-551.
  48. Richardson,G.H., Nelson,J.H., Lubnow,R.E. and Schwarberg,R.L.
    Rennin-like enzyme from Mucor pusillus for cheese manufacture
    J Dairy Sci (1967) 50, 1066-1072.

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