Literature for peptidase A01.013: mucorpepsin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, A Assay, I Inhibitor, P Specificity, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2019

Soltani,M., Sahingil,D., Gokce,Y. and Hayaloglu,A.A. Effect of blends of camel chymosin and microbial rennet (Rhizomucor miehei) on chemical composition, proteolysis and residual coagulant activity in Iranian ultrafiltered white cheese J Food Sci Technol (2019) 56, 589-598. PubMed Europe PubMed DOI PMC EPMC

2018

Stergiou,P.Y., Foukis,A., Gkini,O.A., Barouni,E., Georgoulia,P.S., Kanellaki,M., Koutinas,A.A., Papagianni,M. and Papamichael,E.M. Novel FRET-substrates of Rhizomucor pusillus rennin: activity and mechanistic studies Food Chem (2018) 245, 926-933. PubMed Europe PubMed DOI A
Sun,Q., Chen,F., Geng,F., Luo,Y., Gong,S. and Jiang,Z. A novel aspartic protease from Rhizomucor miehei expressed in Pichia pastoris and its application on meat tenderization and preparation of turtle peptides Food Chem (2018) 245, 570-577. PubMed Europe PubMed DOI

2015

Zhang,J., Sun,Y., Li,Z., Luo,Q., Li,T. and Wang,T. Structure-based design of Mucor pusillus pepsin for the improved ratio of clotting activity/proteolytic activity in cheese manufacture Protein Pept Lett (2015) 22, 660-667. PubMed Europe PubMed

2012

Beppu,T. and Nishiyama,M. Mucorpepsin [ISSN:978-0-12-407744-7] (2012) 3, 154-156. DOI
Garcia,V., Rovira,S., Teruel,R., Boutoial,K., Rodriguez,J., Roa,I. and Lopez,M.B. Effect of vegetable coagulant, microbial coagulant and calf rennet on physicochemical, proteolysis, sensory and texture profiles of fresh goats cheese Dairy Sci Technol (2012) 92, 691-707. DOI

2011

Li,T., Wang,J., Li,Y., Zhang,L., Zheng,L., Li,Z., Yang,Z. and Luo,Q. Stucture of the complex between Mucor pusillus pepsin and the key domain of kappa-casein for site-directed mutagenesis: a combined molecular modeling and docking approach J Mol Model (2011) 17, 1661-1668. PubMed Europe PubMed DOI P

2006

[YEAR:6-3-2006]Machalinski,C., Pirpignani,M.L., Marino,C., Mantegazza,A. and de Jimenez Bonino,M.B. Structural aspects of the Mucor bacilliformis proteinase, a new member of the aspartyl-proteinase family J Biotechnol (6-3-2006) 123, 443-452. PubMed Europe PubMed DOI

2004

Badasso,M.O., Dhanaraj,V., Wood,S.P., Cooper,J.B. and Blundell,T.L. Crystallization and X-ray analysis of the Y75N mutant of Mucor pusillus pepsin complexed with inhibitor Acta Crystallogr D Biol Crystallogr (2004) 60, 770-772. PubMed Europe PubMed DOI S I
Beppu,T. and Nishiyama,M. Mucorpepsin [ISSN:0-12-079610-4] (2004) 2, 111-113. V

2001

Aikawa ,J., Park,Y.N., Sugiyama,M., Nishiyama,M., Horinouchi,S. and Beppu,T. Replacements of amino acid residues at subsites and their effects on the catalytic properties of Rhizomucor pusillus pepsin, an aspartic proteinase from Rhizomucor pusillus J Biochem (2001) 129, 791-794. PubMed Europe PubMed

1999

Awad,S., Luthi-Peng,Q.Q. and Puhan,Z. Proteolytic activities of Suparen and Rennilase on buffalo, cow, and goat whole casein and beta-casein J Agric Food Chem (1999) 47, 3632-3639. PubMed Europe PubMed DOI
Fernandez-Lahore,H.M., Auday,R.M., Fraile,E.R., Biscoglio de Jimenez Bonino,M., Pirpignani,L., Machalinski,C. and Cascone,O. Purification and characterization of an acid proteinase from mesophilic Mucor sp. solid-state cultures J Pept Res (1999) 53, 599-605. PubMed Europe PubMed DOI
Montesino,R., Nimtz,M., Quintero,O., Garcia,R., Falcon,V. and Cremata,J.A. Characterization of the oligosaccharides assembled on the Pichia pastoris-expressed recombinant aspartic protease Glycobiology (1999) 9, 1037-1043. PubMed Europe PubMed DOI E
Yang,J. and Quail,J.W. Structure of the Rhizomucor miehei aspartic proteinase complexed with the inhibitor pepstatin A at 2.7 A resolution Acta Crystallogr D Biol Crystallogr (1999) 55, 625-630. PubMed Europe PubMed DOI S I

1998

Harboe,M.K. Rhizomucor miehei aspartic proteinases having improved properties Adv Exp Med Biol (1998) 436, 293-296. PubMed Europe PubMed
Murakami,K., Takeuchi,K., Beppu,T. and Horinouchi,S. Structure of asparagine-linked oligosaccharides of an aspartic proteinase from the zygomycete fungus Rhizomucor pusillus Microbiology (Reading, Engl.) (1998) 144, 1369-1374. PubMed Europe PubMed

1997

Park,Y.N., Aikawa,J., Nishiyama,M., Horinouchi,S. and Beppu,T. Site-directed mutagenesis of conserved Trp39 in Rhizomucor pusillus pepsin: possible role of Trp39 in maintaining Tyr75 in the correct orientation for maximizing catalytic activity J Biochem (1997) 121, 118-121. PubMed Europe PubMed
Preetha,S. and Boopathy,R. Purification and characterization of a milk clotting protease from Rhizomucor miehei World J Microbiol Biotechnol (1997) 13, 573-578.
Yang,J., Teplyakov,A. and Quail,J.W. Crystal structure of the aspartic proteinase from Rhizomucor miehei at 2.15 A resolution J Mol Biol (1997) 268, 449-459. PubMed Europe PubMed DOI S

1996

Park,Y.N., Aikawa,J., Nishiyama,M., Horinouchi,S. and Beppu,T. Involvement of a residue at position 75 in the catalytic mechanism of a fungal aspartic proteinase, Rhizomucor pusillus pepsin. Replacement of tyrosine 75 on the flap by asparagine enhances catalytic efficiency Protein Eng (1996) 9, 869-875. PubMed Europe PubMed

1995

Beppu,T., Park,Y.N., Aikawa,J., Nishiyama,M. and Horinouchi,S. Tyrosine 75 on the flap contributes to enhance catalytic efficiency of a fungal aspartic proteinase, Mucor pusillus pepsin Adv Exp Med Biol (1995) 362, 501-509. PubMed Europe PubMed
Jia,Z., Vandonselaar,M., Schneider,P. and Quail,J.W. Crystallization and preliminary X-ray structure solution of Rhizomucor miehei aspartic proteinase Acta Crystallogr D Biol Crystallogr (1995) 51, 243-244. PubMed Europe PubMed DOI S
Park,Y.N., Nishiyama,M., Horinouchi,S. and Beppu,T. Site-directed mutagenesis revealed role of subsite residues of Mucor pusillus pepsin in catalytic function Adv Exp Med Biol (1995) 362, 559-563. PubMed Europe PubMed

1993

Newman,M., Watson,F., Roychowdhury,P., Jones,H., Badasso,M., Cleasby,A., Wood,S.P., Tickle,I.J. and Blundell,T.L. X-ray analyses of aspartic proteinases. V. Structure and refinement at 2.0 A resolution of the aspartic proteinase from Mucor pusillus J Mol Biol (1993) 230, 260-283. PubMed Europe PubMed DOI S

1992

Areces,L.B., Bonino,M.B., Parry,M.A., Fraile,E.R., Fernandez,H.M. and Cascone,O. Purification and characterization of a milk clotting protease from Mucor bacilliformis Appl Biochem Biotechnol (1992) 37, 283-294. PubMed Europe PubMed DOI

1991

Smith,L.J. and Yada,Y.R. Chemical modification of amino groups in Mucor miehei aspartyl proteinase, porcine pepsin, and chymosin. II. Conformational stability Agric Biol Chem (1991) 55, 2017-2024. DOI
Smith,L.J., Billings,E.G. and Yada,Y.R. Chemical modification of amino groups in Mucor miehei aspartyl proteinase, porcine pepsin, and chymosin. I. Structure and function Agric Biol Chem (1991) 55, 2009-2016. DOI

1989

[YEAR:5-10-1989]Hiramatsu,R., Aikawa,J., Horinouchi,S. and Beppu,T. Secretion by yeast of the zymogen form of Mucor rennin, an aspartic proteinase of Mucor pusillus, and its conversion to the mature form J Biol Chem (5-10-1989) 264, 16862-16866. PubMed Europe PubMed E

1988

Baudys,M., Foundling,S., Pavlik,M., Blundell,T. and Kostka,V. Protein chemical characterization of Mucor pusillus aspartic proteinase. Amino acid sequence homology with the other aspartic proteinases, disulfide bond arrangement and site of carbohydrate attachment FEBS Lett (1988) 235, 271-274. PubMed Europe PubMed DOI
Christensen,T., Woeldike,H., Boel,E., Mortensen,S.B., Hjortshoej,K., Thim,L. and Hansen,M.T. High-level expression of recombinant genes in Aspergillus oryzae Biotechnology (N Y) (1988) 6, 1419-1422.

1987

Yamashita,T., Tonouchi,N., Uozumi,T. and Beppu,T. Secretion of Mucor rennin, a fungal aspartic protease of Mucor pusillus, by recombinant yeast cells Mol Gen Genet (1987) 210, 462-467. PubMed Europe PubMed DOI

1986

Tonouchi,N., Shoun,H., Uozumi,T. and Beppu,T. Cloning and sequencing of a gene for Mucor rennin, an aspartate protease from Mucor pusillus Nucleic Acids Res (1986) 14, 7557-7568. PubMed Europe PubMed PMC EPMC

1982

Etoh,Y., Shoun,H., Arima,K. and Beppu,T. Photo-oxidation of a histidyl residue of milk-clotting acid protease, mucor rennin J Biochem (1982) 91, 747-753. PubMed Europe PubMed
Etoh,Y., Shoun,H., Ogino,T., Fujiwara,S., Arima,K. and Beppu,T. Proton magnetic resonance spectroscopy of an essential histidyl residue in a milk-clotting acid protease, Mucor rennin J Biochem (1982) 91, 2039-2046. PubMed Europe PubMed

1979

Etoh,Y., Shoun,H., Beppu,T. and Arima,K. Physicochemical and immunochemical studies on similarities of acid proteases Mucor pusillus rennin and Mucor miehei rennin Agric Biol Chem (1979) 43, 209-215.

1976

Takahashi,K., Chang,W.J. and Arima,K. The structure and function of acid proteases. IV. Inactivation of the acid protease from Mucor pusillus by acid protease-specific inhibitors J Biochem (1976) 80, 61-67. PubMed Europe PubMed I

1973

Morihara,K. and Oka,T. Comparative specificity of microbial acid proteinases for synthetic peptides. III. Relationship with their trypsinogen activating ability Arch Biochem Biophys (1973) 157, 561-572. PubMed Europe PubMed P
Oka,T., Ishino,K., Tsuzuki,H., Morihara,K. and Arima,K. On the specificity of a rennin-like enzyme from Mucor pusillus Agric Biol Chem (1973) 37, 1177-1184. P

1972

Sternberg,M. Bond specificity, active site and milk clotting mechanism of the Mucor miehei protease Biochim Biophys Acta (1972) 285, 383-392. PubMed Europe PubMed

1971

Sternberg,M.Z. Crystalline milk-clotting protease from Mucor miehei and some of its properties J Dairy Sci (1971) 54, 150-167.
Voynick,I.M. and Fruton,J.S. The comparative specificity of acid proteinases Proc Natl Acad Sci U S A (1971) 68, 257-259. PubMed Europe PubMed PMC EPMC P

1970

Arima,K., Yu,J. and Iwasaki,S. Milk-clotting enzyme from Mucor pusillus var. lindt Methods Enzymol (1970) 19, 446-459. DOI V
Ottesen,M. and Rickert,W. The acid protease of Mucor miehei Methods Enzymol (1970) 19, 459-460. V

1969

Yu,J., Tamura,G. and Arima,K. Milk clotting enzyme from microorganisms. VI. Properties of crystalline milk-clotting enzyme (mucor rennin) isolated from Mucor pusillus var. lindt BBA - Enzymology (1969) 171, 138-144. PubMed Europe PubMed

1968

Somkuti,G.A. and Babel,F.J. Purification and properties of Mucor pusillus acid protease J Bacteriol (1968) 95, 1407-1414. PubMed Europe PubMed PMC EPMC

1967

Iwasaki,S., Tamura,G. and Arima,K. Milk clotting enzyme from microorganisms. Part II. The enzyme production and the properties of crude enzyme Agric Biol Chem (1967) 31, 546-551.
Richardson,G.H., Nelson,J.H., Lubnow,R.E. and Schwarberg,R.L. Rennin-like enzyme from Mucor pusillus for cheese manufacture J Dairy Sci (1967) 50, 1066-1072.