Structure for peptidase S11.008: penicillin-binding protein 5-type peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

PDB Organism Resolution Comment
3BEC Escherichia coli 1.60 Å complex with peptide-mimetic penicillin
Catalytic residues are shown in ball-and-stick representation: Ser73 and Ser110 in orange and Lys76 in purple. The bound peptide-mimetic penicillin is shown in grey ball-and-stick representation.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Escherichia coli
deacylation defective mutant 2.30 Å 1HD8 1HD8 1HD8 1HD8 1HD8 1HD8 Davies et al., 2001
Asp105Gly deacylation defective mutant 1.90 Å 1NJ4 1NJ4 1NJ4 1NJ4 1NJ4 1NJ4 Nicholas et al., 2003
mature  peptidase 1.85 Å 1NZO 1NZO 1NZO 1NZO 1NZO 1NZO Nicholas et al., 2003
mature  peptidase 2.00 Å 1NZU 1NZU 1NZU 1NZU 1NZU 1NZU Nicola et al., 2005
mature  peptidase 2.50 Å 1SDN 1SDN 1SDN 1SDN 1SDN 1SDN Nicola et al., 2005
mature  peptidase 1.60 Å 1Z6F 1Z6F 1Z6F 1Z6F 1Z6F 1Z6F Nicola et al., 2005
complex with peptide-mimetic penicillin 2.00 Å 3BEB 3BEB 3BEB 3BEB 3BEB 3BEB Sauvage et al., 2008
complex with peptide-mimetic penicillin 1.60 Å 3BEC 3BEC 3BEC 3BEC 3BEC 3BEC Sauvage et al., 2008
mature  peptidase 1.90 Å 3MZD 3MZD 3MZD 3MZD 3MZD 3MZD Nicola et al., 2010
mature  peptidase 2.10 Å 3MZE 3MZE 3MZE 3MZE 3MZE 3MZE Nicola et al., 2010
mature  peptidase 1.50 Å 3MZF 3MZF 3MZF 3MZF 3MZF 3MZF Nicola et al., 2010
crystal structure of e. coli pbp5 with 2c 2.53 Å 5J8X 5J8X 5J8X 5J8X 5J8X 5J8X