Literature for peptidase S11.008: penicillin-binding protein 5-type peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, P Specificity, I Inhibitor, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

    2022
  1. Park,S.H., Choi,U., Ryu,S.H., Lee,H.B., Lee,J.W. and Lee,C.R.<br>Divergent Effects of Peptidoglycan Carboxypeptidase DacA on Intrinsic beta-Lactam and Vancomycin Resistance<br>Microbiol Spectr (2022) 10, e0173422-e0173422. PubMed  Europe PubMed DOI  PMC  EPMC
  2. 2021
  3. Mallick,S., Kiran,S., Maiti,T.K. and Ghosh,A.S.<br>PBP4 and PBP5 are involved in regulating exopolysaccharide synthesis during Escherichia coli biofilm formation<br>Microbiology (Reading) (2021) PubMed  Europe PubMed DOI
  4. 2019
  5. Yang,H., Hu,J., Lu,X., Wang,F., Shen,W., Hu,W., Wang,L., Chen,X. and Liu,L.<br>Improving extracellular protein production in Escherichia coli by overexpressing D,D-carboxypeptidase to perturb peptidoglycan network synthesis and structure<br>Appl Microbiol Biotechnol (2019) 103, 793-806. PubMed  Europe PubMed DOI  E
  6. 2015
  7. Moll,A., Dorr,T., Alvarez,L., Davis,B.M., Cava,F. and Waldor,M.K.<br>A D, D-carboxypeptidase is required for Vibrio cholerae halotolerance<br>Environ Microbiol (2015) 17, 527-540. PubMed  Europe PubMed DOI
  8. 2012
  9. Dzhekieva,L., Kumar,I. and Pratt,R.F.<br>Inhibition of bacterial DD-peptidases (penicillin-binding proteins) in membranes and in vivo by peptidoglycan-mimetic boronic acids<br>Biochemistry (2012) 51, 2804-2811. PubMed  Europe PubMed DOI  I
  10. Kumarasiri,M., Fisher,J.F. and Mobashery,S.<br>Penicillin-binding protein 5 of Escherichia coli<br>[ISSN:978-0-12-407742-3] (2012) 3, 3474-3480. DOI
  11. 2011
  12. Chowdhury,C. and Ghosh,A.S.<br>Differences in active-site microarchitecture explain the dissimilar behaviors of PBP5 and 6 in Escherichia coli<br>J Mol Graph Model (2011) 29, 650-656. PubMed  Europe PubMed DOI
  13. Nemmara,V.V., Dzhekieva,L., Subarno Sarkar,K., Adediran,S.A., Duez,C., Nicholas,R.A. and Pratt,R.F.<br>Substrate specificity of low-molecular mass bacterial dd-peptidases<br>Biochemistry (2011) 50, 10091-10101. PubMed  Europe PubMed DOI  P
  14. 2010
  15. Nicola,G., Tomberg,J., Pratt,R.F., Nicholas,R.A. and Davies,C.<br>Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity<br>Biochemistry (2010) 49, 8094-8104. PubMed  Europe PubMed DOI  PMC  EPMC  S
  16. O'Daniel,P.I., Zajicek,J., Zhang,W., Shi,Q., Fisher,J.F. and Mobashery,S.<br>Elucidation of the structure of the membrane anchor of penicillin-binding protein 5 of Escherichia coli<br>J Am Chem Soc (2010) 132, 4110-4118. PubMed  Europe PubMed DOI  PMC  EPMC  S
  17. Potluri,L., Karczmarek,A., Verheul,J., Piette,A., Wilkin,J.M., Werth,N., Banzhaf,M., Vollmer,W., Young,K.D., Nguyen-Disteche,M. and den Blaauwen,T.<br>Septal and lateral wall localization of PBP5, the major D,D-carboxypeptidase of Escherichia coli, requires substrate recognition and membrane attachment<br>Mol Microbiol (2010) 77, 300-323. PubMed  Europe PubMed DOI
  18. 2008
  19. Ghosh,A.S., Chowdhury,C. and Nelson,D.E.<br>Physiological functions of D-alanine carboxypeptidases in Escherichia coli<br>Trends Microbiol (2008) 16, 309-317. PubMed  Europe PubMed DOI
  20. Sauvage,E., Powell,A.J., Heilemann,J., Josephine,H.R., Charlier,P., Davies,C. and Pratt,R.F.<br>Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle<br>J Mol Biol (2008) 381, 383-393. PubMed  Europe PubMed DOI  PMC  EPMC  S
  21. Shi,Q., Meroueh,S.O., Fisher,J.F. and Mobashery,S.<br>Investigation of the mechanism of the cell wall dd-carboxypeptidase reaction of penicillin-binding protein 5 of Escherichia coli by quantum mechanics/molecular mechanics calculations<br>J Am Chem Soc (2008) 130, 9293-9303. PubMed  Europe PubMed DOI
  22. 2007
  23. Zhang,W., Shi,Q., Meroueh,S.O., Vakulenko,S.B. and Mobashery,S.<br>Catalytic mechanism of penicillin-binding protein 5 of Escherichia coli<br>Biochemistry (2007) 46, 10113-10121. PubMed  Europe PubMed DOI
  24. 2006
  25. Priyadarshini,R., Popham,D.L. and Young,K.D.<br>Daughter cell separation by penicillin-binding proteins and peptidoglycan amidases in Escherichia coli<br>J Bacteriol (2006) 188, 5345-5355. PubMed  Europe PubMed DOI  PMC  EPMC
  26. 2005
  27. Nicola,G., Peddi,S., Stefanova,M., Nicholas,R.A., Gutheil,W.G. and Davies,C.<br>Crystal structure of Escherichia coli penicillin-binding protein 5 bound to a tripeptide boronic acid inhibitor: a role for Ser-110 in deacylation<br>Biochemistry (2005) 44, 8207-8217. PubMed  Europe PubMed DOI  S  I
  28. Nicola,G., Fedarovich,A., Nicholas,R.A. and Davies,C.<br>A large displacement of the SXN motif of Cys115-modified penicillin-binding protein 5 from Escherichia coli<br>Biochem J (2005) 392, 55-63. PubMed  Europe PubMed DOI  PMC  EPMC
  29. 2004
  30. [YEAR:6-2-2004]Hesek,D., Suvorov,M., Morio,K., Lee,M., Brown,S., Vakulenko,S.B. and Mobashery,S.<br>Synthetic peptidoglycan substrates for penicillin-binding protein 5 of Gram-negative bacteria<br>J Org Chem (6-2-2004) 69, 778-784. PubMed  Europe PubMed DOI
  31. 2003
  32. Nicholas,R.A., Krings,S., Tomberg,J., Nicola,G. and Davies,C.<br>Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complex<br>J Biol Chem (2003) 278, 52826-52833. PubMed  Europe PubMed DOI  S
  33. 2002
  34. Stefanova,M.E., Davies,C., Nicholas,R.A. and Gutheil,W.G.<br>pH, inhibitor, and substrate specificity studies on Escherichia coli penicillin-binding protein 5<br>Biochim Biophys Acta (2002) 1597, 292-300. PubMed  Europe PubMed DOI
  35. 2001
  36. Beadle,B.M., Nicholas,R.A. and Shoichet,B.K.<br>Interaction energies between beta-lactam antibiotics and E. coli penicillin-binding protein 5 by reversible thermal denaturation<br>Protein Sci (2001) 10, 1254-1259. PubMed  Europe PubMed DOI  PMC  EPMC
  37. [YEAR:5-1-2001]Davies,C., White,S.W. and Nicholas,R.A.<br>Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3-A resolution<br>J Biol Chem (5-1-2001) 276, 616-623. PubMed  Europe PubMed DOI  S
  38. Nelson,D.E. and Young,K.D.<br>Contributions of PBP 5 and DD-carboxypeptidase penicillin binding proteins to maintenance of cell shape in Escherichia coli<br>J Bacteriol (2001) 183, 3055-3064. PubMed  Europe PubMed DOI  PMC  EPMC
  39. 2000
  40. Nelson,D.E. and Young,K.D.<br>Penicillin binding protein 5 affects cell diameter, contour, and morphology of Escherichia coli<br>J Bacteriol (2000) 182, 1714-1721. PubMed  Europe PubMed DOI  PMC  EPMC
  41. 1998
  42. [YEAR:15-5-1998]Gutheil,W.G.<br>A sensitive equilibrium-based assay for D-lactate using D-lactate dehydrogenase: application to penicillin-binding protein/DD-carboxypeptidase activity assays<br>Anal Biochem (15-5-1998) 259, 62-67. PubMed  Europe PubMed DOI  A
  43. 1994
  44. [YEAR:15-10-1994]van der Linden,M.P., de Haan,L., Dideberg,O. and Keck,W.<br>Site-directed mutagenesis of proposed active-site residues of penicillin-binding protein 5 from Escherichia coli<br>Biochem J (15-10-1994) 303, 357-362. PubMed  Europe PubMed  PMC  EPMC
  45. 1993
  46. [YEAR:15-1-1993]van der Linden,M.P., de Haan,L. and Keck,W.<br>Domain organization of penicillin-binding protein 5 from Escherichia coli analysed by C-terminal truncation<br>Biochem J (15-1-1993) 289, 593-598. PubMed  Europe PubMed  PMC  EPMC
  47. 1992
  48. [YEAR:5-6-1992]Malhotra,K.T. and Nicholas,R.A.<br>Substitution of lysine 213 with arginine in penicillin-binding protein 5 of Escherichia coli abolishes D-alanine carboxypeptidase activity without affecting penicillin binding<br>J Biol Chem (5-6-1992) 267, 11386-11391. PubMed  Europe PubMed
  49. [YEAR:15-2-1992]van der Linden,M.P., Mottl,H. and Keck,W.<br>Cytoplasmic high-level expression of a soluble, enzymatically active form of the Escherichia coli penicillin-binding protein 5 and purification by dye chromatography<br>Eur J Biochem (15-2-1992) 204, 197-202. PubMed  Europe PubMed
  50. 1990
  51. Phoenix,D.A.<br>Investigation into structural features of the Escherichia coli penicillin-binding protein 5 C-terminal anchor<br>Biochem Soc Trans (1990) 18, 948-949. PubMed  Europe PubMed
  52. [YEAR:20-6-1990]Phoenix,D.A. and Pratt,J.M.<br>pH-induced insertion of the amphiphilic alpha-helical anchor of Escherichia coli penicillin-binding protein 5<br>Eur J Biochem (20-6-1990) 190, 365-369. PubMed  Europe PubMed DOI
  53. 1988
  54. [YEAR:15-1-1988]Ferreira,L.C., Schwarz,U., Keck,W., Charlier,P., Dideberg,O. and Ghuysen,J.M.<br>Properties and crystallization of a genetically engineered, water-soluble derivative of penicillin-binding protein 5 of Escherichia coli K12<br>Eur J Biochem (15-1-1988) 171, 11-16. PubMed  Europe PubMed
  55. [YEAR:5-2-1988]Nicholas,R.A. and Strominger,J.L.<br>Site-directed mutants of a soluble form of penicillin-binding protein 5 from Escherichia coli and their catalytic properties<br>J Biol Chem (5-2-1988) 263, 2034-2040. PubMed  Europe PubMed
  56. 1987
  57. Jackson,M.E. and Pratt,J.M.<br>An 18 amino acid amphiphilic helix forms the membrane-anchoring domain of the Escherichia coli penicillin-binding protein 5<br>Mol Microbiol (1987) 1, 23-28. PubMed  Europe PubMed
  58. 1986
  59. Pratt,J.M., Jackson,M.E. and Holland,I.B.<br>The C terminus of penicillin-binding protein 5 is essential for localisation to the E. coli inner membrane<br>EMBO J (1986) 5, 2399-2405. PubMed  Europe PubMed  PMC  EPMC
  60. 1985
  61. Broome-Smith,J.K.<br>Construction of a mutant of Escherichia coli that has deletions of both the penicillin-binding protein 5 and 6 genes<br>J Gen Microbiol (1985) 131, 2115-2118. PubMed  Europe PubMed
  62. [YEAR:25-5-1985]Nicholas,R.A., Ishino,F., Park,W., Matsuhashi,M. and Strominger,J.L.<br>Purification and sequencing of the active site tryptic peptide from penicillin-binding protein 5 from the dacA mutant strain of Escherichia coli (TMRL 1222)<br>J Biol Chem (25-5-1985) 260, 6394-6397. PubMed  Europe PubMed
  63. 1984
  64. Broome-Smith,J. and Spratt,B.G.<br>An amino acid substitution that blocks the deacylation step in the enzyme mechanism of penicillin-binding protein 5 of Escherichia coli<br>FEBS Lett (1984) 165, 185-189. PubMed  Europe PubMed
  65. 1980
  66. Amanuma,H. and Strominger,J.L.<br>Purification and properties of penicillin-binding proteins 5 and 6 from Escherichia coli membranes<br>J Biol Chem (1980) 255, 11173-11180. PubMed  Europe PubMed
  67. 1946
  68. Duguid,J.P.<br>The sensitivity of bacteria to the action of penicillin<br>Edinb Med J (1946) 53, 401-412. PubMed  Europe PubMed