Structure for peptidase M13.001: neprilysin

PDB	Organism	Resolution	Comment
1DMT_A	Homo sapiens	2.10 Å	complex with phosphoramidon
The catalytic zinc is shown as a light grey CPK sphere. The zinc ligands are shown in ball-and-stick representation: His583 and His587 in purple and Glu646 in blue. The catalytic residues are shown in ball-and-stick representation: Glu584 in blue and Asp650 in pink. Carbohydrates are shown as CPK spheres in yellow.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Homo sapiens
theoretical model of peptidase domain (residues 507-749)	0.00 Å	1DL9	1DL9	1DL9	1DL9	1DL9	1DL9
complex with phosphoramidon	2.10 Å	1DMT	1DMT	1DMT	1DMT	1DMT	1DMT	Oefner et al., 2000
mature peptidase	0.00 Å	1QVD	1QVD	1QVD	1QVD	1QVD	1QVD
structural analysis of neprilysin with various specific and potent inhibitors	1.95 Å	1R1H	1R1H	1R1H	1R1H	1R1H	1R1H	Oefner et al., 2004
structural analysis of neprilysin with various specific and potent inhibitors	2.60 Å	1R1I	1R1I	1R1I	1R1I	1R1I	1R1I	Oefner et al., 2004
structural analysis of neprilysin with various specific and potent inhibitors	2.35 Å	1R1J	1R1J	1R1J	1R1J	1R1J	1R1J	Oefner et al., 2004
complex with an imidazo[4, 5-C]pyridine inhibitor	2.25 Å	1Y8J	1Y8J	1Y8J	1Y8J	1Y8J	1Y8J
human nep complexed with a bifunctional nep/dpp iv inhibitor	2.05 Å	2QPJ	2QPJ	2QPJ	2QPJ	2QPJ	2QPJ	Oefner et al., 2007
mature peptidase	2.40 Å	2YB9	2YB9	2YB9	2YB9	2YB9	2YB9	Glossop et al., 2011
mature peptidase	2.15 Å	4CTH	4CTH	4CTH	4CTH	4CTH	4CTH	Webster et al., 2014
neprilysin complex with lbq657	2.00 Å	5JMY	5JMY	5JMY	5JMY	5JMY	5JMY
mature peptidase	1.90 Å	6GID	6GID	6GID	6GID	6GID	6GID
Mus musculus
mature peptidase	3.20 Å	2YVC	2YVC	2YVC	2YVC	2YVC	2YVC	Terawaki et al., 2007
Oryctolagus cuniculus
soluble rabbit neprilysin	2.11 Å	4XBH	4XBH	4XBH	4XBH	4XBH	4XBH
complex with phosphoramidon	2.80 Å	4ZR5	4ZR5	4ZR5	4ZR5	4ZR5	4ZR5
soluble rabbit neprilysin in complex with thiorphan	3.00 Å	5V48	5V48	5V48	5V48	5V48	5V48