Structure for peptidase M01.024: ERAP2 aminopeptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

PDB Organism Resolution Comment
3SE6 Homo sapiens 3.08 Å mature
The catalytic zinc atom is shown as a light grey CPK sphere. The zinc ligands are shown in ball-and-stick representation: His370 in purple, His374 in purple and Glu393 in blue. The catalytic residues are shown in ball-and-stick representation: Glu371 in blue and Tyr455 in green.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Homo sapiens
mature  peptidase 3.08 Å 3SE6 3SE6 3SE6 3SE6 3SE6 3SE6 Birtley et al., 2012
mature  peptidase 3.22 Å 4E36 4E36 4E36 4E36 4E36 4E36 Evnouchidou et al., 2012
mature  peptidase 2.79 Å 4JBS 4JBS 4JBS 4JBS 4JBS 4JBS Zervoudi et al., 2013
mature  peptidase 2.50 Å 5AB0 5AB0 5AB0 5AB0 5AB0 5AB0 Mpakali et al., 2015
mature  peptidase 2.73 Å 5AB2 5AB2 5AB2 5AB2 5AB2 5AB2 Mpakali et al., 2015
mature  peptidase 3.02 Å 5CU5 5CU5 5CU5 5CU5 5CU5 5CU5 Mpakali et al., 2015
complex with a hydroxamic derivative ligand 2.80 Å 5J6S 5J6S 5J6S 5J6S 5J6S 5J6S
complex with a diaminobenzoic acid derivative ligand. 2.90 Å 5K1V 5K1V 5K1V 5K1V 5K1V 5K1V