Structure for peptidase C19.013: ubiquitin-specific peptidase 2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

PDB Organism Resolution Comment
2IBI Homo sapiens 2.20 Å complex with ubiquitin
Catalytic residues are shown in ball-and-stick representation: Asn287 and Asn574 in pink, Cys292 in yellow and His557 in purple. The structural zinc atom is shown as a light grey CPK sphere. The bound ubiquitin is shown in grey ribbon representation.
This browser does not have a Java Plug-in.
Get the latest Java Plug-in here.
Show surface
TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Homo sapiens
complex with ubiquitin 1.85 Å 2HD5 2HD5 2HD5 2HD5 2HD5 2HD5 Renatus et al., 2006
complex with ubiquitin 2.20 Å 2IBI 2IBI 2IBI 2IBI 2IBI 2IBI
mature  peptidase 1.26 Å 3NHE 3NHE 3NHE 3NHE 3NHE 3NHE
mature  peptidase 1.70 Å 3V6C 3V6C 3V6C 3V6C 3V6C 3V6C
mature  peptidase 2.10 Å 3V6E 3V6E 3V6E 3V6E 3V6E 3V6E Ernst et al., 2013
complex with ubiquitin and 6- thioguanine 1.81 Å 5XU8 5XU8 5XU8 5XU8 5XU8 5XU8
Cys276Ser mutant; complex with ubiquitin 1.24 Å 5XVE 5XVE 5XVE 5XVE 5XVE 5XVE
ubiquitin variant bound to usp2 2.34 Å 6DGF 6DGF 6DGF 6DGF 6DGF 6DGF