Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence Q9UBE0

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-346	P	release of an initiating methionine	MS	Van Damme P et al., 2005
98	trypsin 1	1-346	N		MS	Schilling & Overall, 2008
109	trypsin 1	1-346	N		MS	Schilling & Overall, 2008
117	trypsin 1	1-346	N		MS	Schilling & Overall, 2008
170	cathepsin S	153-178	N		MS	Biniossek et al., 2011
196	trypsin 1	1-346	N		MS	Schilling & Overall, 2008
208	trypsin 1	1-346	N		MS	Schilling & Overall, 2008
273	trypsin 1	1-346	N		MS	Schilling & Overall, 2008
285	granzyme B (Homo sapiens-type)	1-346	N		MS	Van Damme et al., 2010
293	trypsin 1	1-346	N		MS	Schilling & Overall, 2008
303	cathepsin B	294-316	N		MS	Biniossek et al., 2011
304	cathepsin B	294-316	N		MS	Biniossek et al., 2011
304	matrix metallopeptidase-2	293-316	N		MS	Schilling & Overall, 2008
307	cathepsin B	294-316	N		MS	Biniossek et al., 2011
308	matrix metallopeptidase-2	296-318	N		MS	Schilling & Overall, 2008
316	trypsin 1	1-346	N		MS	Schilling & Overall, 2008
318	chymotrypsin A (cattle-type)	1-346	N		MS	Schilling & Overall, 2008
327	matrix metallopeptidase-2	313-341	N		MS	Schilling & Overall, 2008
341	glutamyl endopeptidase I	1-346	N		MS	Schilling & Overall, 2008