Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q9GZV4

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-153	P		NT	<%Agarwal et al., 2012[]%>
39	trypsin 1	2-153	N		MS	Schilling & Overall, 2008
47	trypsin 1	2-153	N		MS	Schilling & Overall, 2008
57	matrix metallopeptidase-2	55-67	N		MS	Schilling & Overall, 2008
67	trypsin 1	2-153	N		MS	Schilling & Overall, 2008
70	cathepsin L	69-85	N		MS	Biniossek et al., 2011
70	cathepsin S	69-85	N		MS	Biniossek et al., 2011
70	glutamyl endopeptidase I	68-85	N		MS	Schilling & Overall, 2008
75	cathepsin S	69-85	N		MS	Biniossek et al., 2011
75	elastase-2	68-85	N		MS	Schilling & Overall, 2008
85	trypsin 1	2-153	N		MS	Schilling & Overall, 2008