Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q9CXW4

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-178	P		NT	<%Agarwal et al., 2012[]%>
4	granzyme B (Homo sapiens-type)	2-178	N			Van Damme et al., 2009
4	granzyme B, rodent-type	2-178	P			Van Damme et al., 2009
13	trypsin 1	2-178	N			Van Damme et al., 2009
22	cathepsin D	2-178	P		MS	Impens et al., 2010
22	cathepsin E	2-178	P		MS	Impens et al., 2010
23	cathepsin E	2-178	P		MS	Impens et al., 2010
40	cathepsin D	2-178	P		MS	Impens et al., 2010