Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence Q7KZF4

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-910	P		NT	<%Agarwal et al., 2012[]%>
124	LAST_MAM peptidase (Limulus-type)	121-135	N		MS	Becker-Pauly et al., 2011
195	elastase-2	184-203	N		MS	Schilling & Overall, 2008
203	trypsin 1	1-910	N		MS	Schilling & Overall, 2008
351	cathepsin L	347-359	N		MS	Biniossek et al., 2011
446	cathepsin L	439-457	N		MS	Biniossek et al., 2011
506	matrix metallopeptidase-2	493-520	N		MS	Schilling & Overall, 2008
510	granzyme B (Homo sapiens-type)	2-910	N		MS	Van Damme et al., 2010
520	chymotrypsin A (cattle-type)	1-910	N		MS	Schilling & Overall, 2008
699	meprin alpha subunit	2-910	N		MS	Becker-Pauly et al., 2011
699	meprin beta subunit	2-910	N		MS	Becker-Pauly et al., 2011
719	cathepsin L	716-731	N		MS	Biniossek et al., 2011
720	meprin beta subunit	717-731	N		MS	Becker-Pauly et al., 2011