Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence Q13428

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
68	granzyme B (Homo sapiens-type)	1-1488	N		MS	Van Damme et al., 2010
166	granzyme B (Homo sapiens-type)	1-1488	N		MS	Van Damme et al., 2010
221	granzyme B (Homo sapiens-type)	1-1488	N		MS	Van Damme et al., 2010
421	meprin beta subunit	418-432	N		MS	Becker-Pauly et al., 2011
437	granzyme A	1-1488	N			Van Damme et al., 2010
474	granzyme B (Homo sapiens-type)	1-1488	N		MS	Van Damme et al., 2010
493	cathepsin S	487-502	N		MS	Biniossek et al., 2011
591	trypsin 1	1-1488	N		MS	Schilling & Overall, 2008
599	peptidyl-Lys metallopeptidase	1-1488	N		MS
600	trypsin 1	1-1488	N		MS	Schilling & Overall, 2008
632	peptidyl-Lys metallopeptidase	1-1488	N		MS
865	granzyme B (Homo sapiens-type)	1-1488	N		MS	Van Damme et al., 2010
867	granzyme B (Homo sapiens-type)	1-1488	N		MS	Van Damme et al., 2010
897	granzyme A	1-1488	N			Van Damme et al., 2010
1034	granzyme A	1-1488	N			Van Damme et al., 2010
1101	unknown peptidase		P		MS	Mahrus et al., 2008
1242	caspase-3	1-1488	P		MS	Impens et al., 2010
1259	granzyme A	1-1488	N			Van Damme et al., 2010
1409	cathepsin L	1406-1423	N		MS	Biniossek et al., 2011