Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q13177

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-524	P	release of an initiating methionine	MS	Van Damme P et al., 2005
104	thrombin	100-115	N		MS	Schilling & Overall, 2008
115	glutamyl endopeptidase I	1-524	N		MS	Schilling & Overall, 2008
148	unknown peptidase		P		MS	Mahrus et al., 2008
203	LAST_MAM peptidase (Limulus-type)	200-216	N		MS	Becker-Pauly et al., 2011
212	caspase-3	1-524	P			<%Walter et al., 1998[]%>