Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P63241

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-154	P		NT	<%Agarwal et al., 2012[]%>
6	unknown peptidase		P		MS	Mahrus et al., 2008
8	granzyme B (Homo sapiens-type)	2-154	N		MS	Van Damme et al., 2010
11	unknown peptidase		P		MS	Mahrus et al., 2008
26	trypsin 1	2-154	N			Van Damme et al., 2009
39	trypsin 1	2-154	N		MS	Schilling & Overall, 2008
47	trypsin 1	2-154	N		MS	Schilling & Overall, 2008
85	trypsin 1	2-154	N		MS	Schilling & Overall, 2008
86	trypsin 1	2-154	N		MS	Schilling & Overall, 2008
96	LAST_MAM peptidase (Limulus-type)	93-109	N		MS	Becker-Pauly et al., 2011
109	trypsin 1	2-154	N		MS	Schilling & Overall, 2008
142	cathepsin S	127-150	N		MS	Biniossek et al., 2011