Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P62960

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-322	P		NT	<%Agarwal et al., 2012[]%>
56	matrix metallopeptidase-2	2-322	N		MS	auf dem Keller et al., 2010
109	cathepsin D	2-322	P		MS	Impens et al., 2010
109	cathepsin E	2-322	P		MS	Impens et al., 2010
155	matrix metallopeptidase-2	2-322	N		MS	auf dem Keller et al., 2010
159	matrix metallopeptidase-2	2-322	N		MS	auf dem Keller et al., 2010
162	matrix metallopeptidase-2	2-322	N		MS	auf dem Keller et al., 2010
202	matrix metallopeptidase-2	2-322	N		MS	auf dem Keller et al., 2010
214	unknown peptidase	2-322	P			Van Damme et al., 2009
217	unknown peptidase	1-322	P		NT	<%Agarwal et al., 2012[]%>
229	trypsin 1	2-322	N			Van Damme et al., 2009
256	granzyme B (Homo sapiens-type)	2-322	N			Van Damme et al., 2009
256	granzyme B, rodent-type	2-322	P			Van Damme et al., 2009
267	granzyme B (Homo sapiens-type)	2-322	N		MS	Van Damme et al., 2009
277	trypsin 1	2-322	N			Van Damme et al., 2009