Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P62841

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-145	P		NT	<%Agarwal et al., 2012[]%>
23	granzyme B (Homo sapiens-type)	2-145	N		MS	Van Damme et al., 2010
27	granzyme B (Homo sapiens-type)	2-145	P		MS	Van Damme et al., 2009
31	granzyme B (Homo sapiens-type)	2-145	N		MS	Plasman et al., 2011
40	trypsin 1	2-145	N			Van Damme et al., 2009
65	trypsin 1	2-145	N		MS	Schilling & Overall, 2008
66	astacin	63-77	N		MS	Becker-Pauly et al., 2011
77	trypsin 1	2-145	N		MS	Schilling & Overall, 2008
81	trypsin 1	2-145	N		MS	Schilling & Overall, 2008
92	matrix metallopeptidase-2	88-106	N		MS	Schilling & Overall, 2008
100	trypsin 1	2-145	N		MS	Schilling & Overall, 2008
106	cathepsin S	101-114	N		MS	Biniossek et al., 2011
106	glutamyl endopeptidase I	2-145	N		MS	Schilling & Overall, 2008
116	HIV-1 retropepsin	107-127	N		MS	Schilling & Overall, 2008
117	meprin beta subunit	114-127	N		MS	Becker-Pauly et al., 2011
118	glutamyl endopeptidase I	108-127	N		MS	Schilling & Overall, 2008
127	trypsin 1	2-145	N		MS	Schilling & Overall, 2008