Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P50580

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-394	P		NT	<%Agarwal et al., 2012[]%>
16	cathepsin D	2-394	P		MS	Impens et al., 2010
16	cathepsin E	2-394	P		MS	Impens et al., 2010
128	cathepsin D	2-394	P		MS	Impens et al., 2010
222	matrix metallopeptidase-2	2-394	N		MS	auf dem Keller et al., 2010
224	cathepsin E	2-394	P		MS	Impens et al., 2010
225	cathepsin E	2-394	P		MS	Impens et al., 2010
227	cathepsin E	2-394	P		MS	Impens et al., 2010
227	granzyme B (Homo sapiens-type)	2-394	N			Van Damme et al., 2009
227	granzyme B, rodent-type	2-394	P			Van Damme et al., 2009
229	cathepsin D	2-394	P		MS	Impens et al., 2010
229	cathepsin E	2-394	P		MS	Impens et al., 2010
243	trypsin 1	2-394	N			Van Damme et al., 2009
282	cathepsin D	2-394	P		MS	Impens et al., 2010
282	cathepsin E	2-394	P		MS	Impens et al., 2010
341	granzyme B (Homo sapiens-type)	2-394	N		MS	Van Damme et al., 2009
346	matrix metallopeptidase-2	2-394	N		MS	Prudova et al., 2010
347	cathepsin D	2-394	P		MS	Impens et al., 2010
347	cathepsin E	2-394	P		MS	Impens et al., 2010
350	cathepsin D	2-394	P		MS	Impens et al., 2010