Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P35555

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
27	unknown peptidase	1-2871	P		NT	<%Agarwal et al., 2012[]%>
449	matrix metallopeptidase-9	28-2871	P	release of a protein domain		Hindson et al., 1999
449	matrix metallopeptidase-13	28-2871	P	release of a protein domain		Hindson et al., 1999
2045	matrix metallopeptidase-12	28-2871	P	normal turnover		Hindson et al., 1999
2731	furin	28-2871	P			Milewicz et al., 1995
2731	PCSK2 peptidase	2726-2735	N		CS	Remacle et al., 2008
2731	PCSK4 peptidase	2726-2735	N		CS	Remacle et al., 2008
2731	PCSK6 peptidase	2726-2735	N		CS	Remacle et al., 2008
2731	PCSK5 peptidase	2726-2735	N		CS	Remacle et al., 2008
2731	PCSK7 peptidase	2726-2735	N		CS	Remacle et al., 2008