Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P23229

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
23	unknown peptidase	1-1097	P	release of a signal peptide	NT	Kajiji et al., 1989
633	urokinase-type plasminogen activator	24-1130	P			Pawar et al., 2007
938	unknown peptidase	1-1130	P		NT	<%Agarwal et al., 2012[]%>
941	furin	24-1130	P	conversion to two-chain form	CS	Lehmann et al., 1996
941	PCSK2 peptidase	936-945	N		CS	Remacle et al., 2008
941	PCSK4 peptidase	936-945	N		CS	Remacle et al., 2008
941	PCSK6 peptidase	936-945	N		CS	Remacle et al., 2008
941	PCSK5 peptidase	936-945	N		CS	Remacle et al., 2008
941	PCSK7 peptidase	936-945	N		CS	Remacle et al., 2008