Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P20800

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
24	unknown peptidase	1-178	P		NT	<%Agarwal et al., 2012[]%>
46	unknown peptidase	1-178	P		NT	<%Agarwal et al., 2012[]%>
64	neprilysin	49-67	P		NT	Vijayaraghavan et al., 1990
66	neprilysin	49-69	P		NT	Vijayaraghavan et al., 1990
69	cathepsin E	25-178	P	release of an activation peptide	AB	Robinson et al., 1992
69	endothelin-converting enzyme 1	25-178	P			Fahnoe et al., 2000
69	Kell blood-group peptidase	25-178	P			Lee et al., 1999
79	chymase (Homo sapiens-type)	25-178	P			Nakano et al., 1997