Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P20783

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site Peptidase Residue range Cleavage type Description Evidence Reference
18 unknown peptidase 1-257 P NT <%Agarwal et al., 2012[]%>
138 kallikrein-related peptidase 4 1-257 P CS Matsumura et al., 2005
138 furin 19-257 P Siedah et al., 1996
138 PCSK2 peptidase 133-142 N CS Remacle et al., 2008
138 PCSK4 peptidase 133-142 N CS Remacle et al., 2008
138 PCSK6 peptidase 19-257 P Siedah et al., 1996
138 PCSK5 peptidase 133-142 N CS Remacle et al., 2008
138 PCSK7 peptidase 133-142 N CS Remacle et al., 2008