Searches of the MEROPS database

Display Known Cleavages for a Protein

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Sequence P09429

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Evidence	Reference
1	unknown peptidase	1-215	P	NT	<%Agarwal et al., 2012[]%>
11	peptidyl-Lys metallopeptidase	1-215	N	MS
27	peptidyl-Lys metallopeptidase	1-215	N	MS
33	meprin alpha subunit	2-215	N	MS	Becker-Pauly et al., 2011
33	meprin beta subunit	2-215	N	MS	Becker-Pauly et al., 2011
33	granzyme B (Homo sapiens-type)	2-215	N	MS	Van Damme et al., 2010
37	granzyme B (Homo sapiens-type)	2-215	N	MS	Van Damme et al., 2010
42	peptidyl-Lys metallopeptidase	1-215	N	MS
111	peptidyl-Lys metallopeptidase	1-215	N	MS
113	peptidyl-Lys metallopeptidase	1-215	N	MS
126	peptidyl-Lys metallopeptidase	1-215	N	MS
128	trypsin 1	2-215	N	MS	Schilling & Overall, 2008
130	cathepsin K	128-146	N	MS	Schilling & Overall, 2008
131	matrix metallopeptidase-2	128-146	N	MS	Schilling & Overall, 2008
131	glutamyl endopeptidase I	128-146	N	MS	Schilling & Overall, 2008
134	cathepsin L	129-146	N	MS	Biniossek et al., 2011
134	cathepsin S	128-146	N	MS	Biniossek et al., 2011
135	astacin	132-147	N	MS	Becker-Pauly et al., 2011
136	cathepsin S	129-146	N	MS	Biniossek et al., 2011
140	peptidyl-Lys metallopeptidase	1-215	N	MS
146	trypsin 1	2-215	N	MS	Schilling & Overall, 2008
147	trypsin 1	2-215	N	MS	Schilling & Overall, 2008