Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P06681

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
20	unknown peptidase	1-752	P	release of a signal peptide	NT	Kerr & Gagnon, 1982
243	complement component activated C1s	21-752	P			Arlaud et al., 2004
243	mannan-binding lectin-associated serine peptidase 1	21-752	P			Schwaeble et al., 2004
243	mannan-binding lectin-associated serine peptidase 2	21-752	P			Matsushita et al., 2000