Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P05155

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
22	unknown peptidase	1-500	P	release of a signal peptide	NT	Harrison 1983
54	HIV-1 retropepsin	23-500	N	pathological turnover		Gerencer & Burek, 2004
55	chymase (Homo sapiens-type)	23-500	P			Raymond et al., 2003
461	matrix metallopeptidase-8	23-500	P		NT	Knauper et al., 1991
466	complement component activated C1r	23-500	P			Duncan et al., 2008
466	complement component activated C1s	23-500	P			Duncan et al., 2008
466	mannan-binding lectin-associated serine peptidase 2	23-500	P			Duncan et al., 2008