Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P01211

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
24	unknown peptidase	1-263	P		NT	<%Agarwal et al., 2012[]%>
95	plasma kallikrein	25-263	N		AA	Metters et al., 1988
96	plasma kallikrein	25-263	N		AA	Metters et al., 1988
103	plasma kallikrein	25-263	N		AA	Metters et al., 1988
109	plasma kallikrein	104-137	N		AA	Metters et al., 1988
110	plasma kallikrein	104-137	N		AA	Metters et al., 1988
125	BACE2 g.p. (Homo sapiens)	125-137	N		MS	Kim et al., 2002
129	BACE2 g.p. (Homo sapiens)	126-135	N		MS	Kim et al., 2002
130	BACE2 g.p. (Homo sapiens)	126-135	N		MS	Kim et al., 2002
131	BACE2 g.p. (Homo sapiens)	126-135	N		MS	Kim et al., 2002
131	plasma kallikrein	104-137	N		AA	Metters et al., 1988
132	BACE2 g.p. (Homo sapiens)	125-137	N		MS	Kim et al., 2002
132	plasma kallikrein	104-137	N		AA	Metters et al., 1988
133	BACE2 g.p. (Homo sapiens)	125-137	N		MS	Kim et al., 2002
181	plasma kallikrein	25-263	N		AA	Metters et al., 1988
191	plasma kallikrein	25-263	N		AA	Metters et al., 1988
203	unknown peptidase	1-263	P		NT	<%Agarwal et al., 2012[]%>
211	plasma kallikrein	206-230	N		AA	Metters et al., 1988
211	unknown peptidase	206-217	N			Tsuchiya et al., 1994
212	epralysin	206-217	N			Kim et al., 1997
212	unknown peptidase	206-217	N			Tsuchiya et al., 1994
217	endothelin-converting enzyme 2	206-223	P		MS	Mzhavia et al., 2003
221	endothelin-converting enzyme 2	206-223	P		MS	Mzhavia et al., 2003
223	unknown peptidase	1-263	P		NT	<%Agarwal et al., 2012[]%>
224	plasma kallikrein	206-230	N		AA	Metters et al., 1988
225	plasma kallikrein	206-230	N		AA	Metters et al., 1988
228	endothelin-converting enzyme 2	206-230	P		MS	Mzhavia et al., 2003
256	plasma kallikrein	233-263	N		AA	Metters et al., 1988