Sequence features for peptidase S09.018: dipeptidyl-peptidase 8

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

MERNUM	Species	Sequence length	Peptidase unit	Active site residues	Source
MER0689736	Acanthisitta chloris	879	628-854	S736, D814, H846	GENBANK:XP_009068803
MER0268874	Ailuropoda melanoleuca	898	647-886	S755, D833, H865	UNIPROT:G1L8B3
MER0268874	Ailuropoda melanoleuca	898	647-886	S755, D833, H865	UNIPROT:G1L8B3
MER0265457	Alligator mississippiensis	896	503-858	S740, D818, H850	GENBANK:XP_006269819
MER0688082	Apaloderma vittatum	885	634-860	S742, D820, H852	GENBANK:XP_009873789
MER0686979	Aptenodytes forsteri	882	631-857	S739, D817, H849	GENBANK:XP_009278696
MER0685554	Aquila chrysaetos	882	631-857	S739, D817, H849	GENBANK:XP_011593748
MER0682022	Balearica regulorum	884	633-859	S741, D819, H851	GENBANK:XP_010311086
MER0679194	Bison bison	898	647-873	S755, D833, H865	GENBANK:XP_010832861
MER0430855	Bos grunniens	898	518-873	S755, D833, H865	GENBANK:XP_005900031
MER0056510	Bos taurus	898	528-885	S755, D833, H865	GENBANK:DAA25815
MER0678858	Buceros rhinoceros	882	631-857	S739, D817, H849	GENBANK:XP_010141369
MER0326386	Callithrix jacchus	882	631-870	S739, D817, H849	GENBANK:XP_002753289
MER0677888	Camelus dromedarius	898	647-873	S755, D833, H865	GENBANK:XP_010991860
MER0675492	Cariama cristata	884	633-859	S741, D819, H851	GENBANK:XP_009703842
MER0998122	Cathartes aura	884	617-867	S741, D819, H851	UNIPROT:A0A091L7S7
MER0998122	Cathartes aura	884	617-867	S741, D819, H851	UNIPROT:A0A091L7S7
MER0103826	Cavia porcellus	903	652-891	S760, D838, H870	GENBANK:XP_003463549
MER0672896	Chaetura pelagica	884	633-859	S741, D819, H851	GENBANK:XP_009993595
MER0671611	Charadrius vociferus	882	631-857	S739, D817, H849	GENBANK:XP_009885190
MER0667307	Corvus cornix	882	631-857	S739, D817, H849	GENBANK:XP_010389253
MER0326398	Cricetulus griseus	892	641-880	S749, D827, H859	GENBANK:XP_003507191
MER0665711	Cuculus canorus	884	633-859	S741, D819, H851	GENBANK:XP_009565883
MER0102339	Dasypus novemcinctus	891	511-866	S748, D826, H858	GENBANK:XP_004453202
MER0599536	Echinops telfairi	859	608-834	S716, D794, H826	GENBANK:XP_004712050
MER0596002	Egretta garzetta	884	633-859	S741, D819, H851	GENBANK:XP_009645397
MER0657970	Eurypyga helias	882	631-857	S739, D817, H849	GENBANK:XP_010159263
MER0654680	Fulmarus glacialis	884	633-859	S741, D819, H851	GENBANK:XP_009574404
MER1000132	Gallus gallus	900	633-883	A740, S757, E818, D835, L850, H867	GENBANK:-
MER1000132	Gallus gallus	900	633-883	A740, S757, E818, D835, L850, H867	GENBANK:-
MER0653635	Gavia stellata	888	637-863	S745, D823, H855	GENBANK:XP_009817436
MER0998172	Gorilla gorilla	901	633-886	S758, D836, H868	UNIPROT:G3RZM4
MER0652555	Haliaeetus albicilla	882	631-857	S739, D817, H849	GENBANK:XP_009928390
MER0651891	Haliaeetus leucocephalus	882	631-857	S739, D817, H849	GENBANK:XP_010570367
MER0489111	Heterocephalus glaber	891	511-866	S748, D826, H858	GENBANK:XP_004877625
MER0013484	Homo sapiens	882	631-869	S739, D817, H849	GENBANK:XP_016877871
MER0013484	Homo sapiens	882	631-869	S739, D817, H849	GENBANK:XP_016877871
MER0013484	Homo sapiens	882	631-869	S739, D817, H849	GENBANK:XP_016877871
MER0013484	Homo sapiens	882	631-869	S739, D817, H849	GENBANK:XP_016877871
MER0013484	Homo sapiens	882	631-869	S739, D817, H849	GENBANK:XP_016877871
MER0013484	Homo sapiens	882	631-869	S739, D817, H849	GENBANK:XP_016877871
MER0013484	Homo sapiens	882	631-869	S739, D817, H849	GENBANK:XP_016877871
MER0013484	Homo sapiens	882	631-869	S739, D817, H849	GENBANK:XP_016877871
MER0013484	Homo sapiens	882	631-869	S739, D817, H849	GENBANK:XP_016877871
MER0013484	Homo sapiens	882	631-869	S739, D817, H849	GENBANK:XP_016877871
MER0414490	Latimeria chalumnae	883	651-873	S740, D818, H850	GENBANK:-
MER0414490	Latimeria chalumnae	883	651-873	S740, D818, H850	GENBANK:-
MER1002540	Leptosomus discolor	884	617-867	S741, D819, H851	UNIPROT:A0A091PJ21
MER1002540	Leptosomus discolor	884	617-867	S741, D819, H851	UNIPROT:A0A091PJ21
MER0259440	Loxodonta africana	898	647-886	S755, D833, H865	GENBANK:XP_003418417
MER0077904	Macaca mulatta	898	647-886	S755, D833, H865	UNIPROT:G7MXU8
MER0077904	Macaca mulatta	898	647-886	S755, D833, H865	UNIPROT:G7MXU8
MER1002895	Macaca mulatta	725	458-710	S582, D660, H692	UNIPROT:F6QBS0
MER0647491	Manacus vitellinus	863	612-838	S720, D798, H830	GENBANK:XP_008921348
MER0644767	Mandrillus leucophaeus	891	640-866	S748, D826, H858	GENBANK:XP_011823568
MER0644339	Merops nubicus	887	636-862	S744, D822, H854	GENBANK:XP_008935399
MER0643326	Mesitornis unicolor	884	633-859	S741, D819, H851	GENBANK:XP_010179230
MER1022908	Monodelphis domestica	882	611-873	S739, D817, H849,	UNIPROT:F6SAE7
MER0017018	Mus musculus	908	625-895	S765, D843, H875	GENBANK:EDL26079
MER0017018	Mus musculus	908	625-895	S765, D843, H875	GENBANK:EDL26079
MER0999138	Myotis davidii	726	501-711	S583, D661, H693	UNIPROT:L5LFQ1
MER0999138	Myotis davidii	726	501-711	S583, D661, H693	UNIPROT:L5LFQ1
MER0640826	Nannospalax galili	892	641-867	S749, D827, H859	GENBANK:XP_008834540
MER1000016	Neovison vison	898	631-883	S755, D833, H865	UNIPROT:U6CTW9
MER1000016	Neovison vison	898	631-883	S755, D833, H865	UNIPROT:U6CTW9
MER0638137	Nestor notabilis	884	633-859	S741, D819, H851	GENBANK:XP_010017173
MER0636543	Nipponia nippon	891	640-866	S748, D826, H858	GENBANK:XP_009468304
MER0326393	Nomascus leucogenys	861	632-871	A740, Y818, N850	GENBANK:XP_003267047
MER0634241	Opisthocomus hoazin	884	633-859	S741, D819, H851	GENBANK:XP_009943726
MER0110401	Oryctolagus cuniculus	892	641-880	S749, D827, H859	GENBANK:XP_002718012
MER0053278	Pan troglodytes	892	522-879	S749, D827, H859	GENBANK:XP_001174486
MER0633281	Pelecanus crispus	889	638-864	S746, D824, H856	GENBANK:XP_009485519
MER0631640	Phaethon lepturus	882	631-857	S739, D817, H849	GENBANK:XP_010284243
MER0631312	Phalacrocorax carbo	886	635-861	S743, D821, H853	GENBANK:XP_009507059
MER0550553	Picoides pubescens	869	618-844	S726, D804, H836	GENBANK:XP_009902185
MER0165228	Pongo abelii	898	647-886	S755, D833, H865	GENBANK:XP_002825613
MER0576083	Pterocles gutturalis	884	633-859	S741, D819, H851	GENBANK:XP_010073826
MER0600879	Pteropus vampyrus	898	647-873	S755, D833, H865	GENBANK:XP_011361619
MER0999195	Pygoscelis adeliae	884	618-867	S741, D819, H851	UNIPROT:A0A093NKK7
MER0999195	Pygoscelis adeliae	884	618-867	S741, D819, H851	UNIPROT:A0A093NKK7
MER0028265	Rattus norvegicus	892	590-879	S749, D827, H859	GENBANK:EDL95811
MER0554808	Rhinopithecus roxellana	891	640-866	S748, D826, H858	GENBANK:XP_010353808
MER0544199	Serinus canaria	882	631-857	S739, D817, H849	GENBANK:XP_009088299
MER0514482	Struthio camelus	882	631-857	S739, D817, H849	GENBANK:XP_009679468
MER0165123	Sus scrofa	898	647-886	S755, D833, H865	GENBANK:XP_001929126
MER0165287	Sus scrofa	782	512-769	missing, D717, H749	GENBANK:XP_001929135
MER1002060	Sus scrofa	311	93-296	S168, D246, H278	GENBANK:-
MER0309978	Tauraco erythrolophus	884	633-859	S741, D819, H851	GENBANK:XP_009986765
MER0480380	Tinamus guttatus	882	631-857	S739, D817, H849	GENBANK:XP_010219443
MER0456731	Tyto alba	886	635-861	S743, D821, H853	GENBANK:XP_009963896
MER0186918	Ursus maritimus	898	647-873	S755, D833, H865	GENBANK:XP_008706804