Merops Switch to
Inhibitors

Peptidase

Family Clan SEARCHES BLAST
MEROPS SUBMISSIONS

Other
information

Sequence features for peptidase S08.071: furin

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

MERNUM Species Sequence length Peptidase unit Active site residues Source
MER0268371 Ailuropoda melanoleuca 793 122-422 D153, H194, N295, S368 UNIPROT:D2HCZ3
MER0268371 Ailuropoda melanoleuca 793 122-422 D153, H194, N295, S368 UNIPROT:D2HCZ3
MER0266831 Alligator mississippiensis 789 132-422 D154, H195, N296, S369 GENBANK:XP_006271198
MER0302218 Alligator sinensis 795 138-428 D160, H201, N302, S375 GENBANK:XP_006030857
MER0403197 Anolis carolinensis 778 100-407 D139, H180, N281, S354 GENBANK:XP_003228975
MER0407928 Balaenoptera acutorostrata 795 131-421 D153, H194, N295, S368 GENBANK:XP_007194370
MER0000384 Bos taurus 797 131-421 D153, H194, N295, S368 UNIPROT:Q28193
MER0000384 Bos taurus 797 131-421 D153, H194, N295, S368 UNIPROT:Q28193
MER0000384 Bos taurus 797 131-421 D153, H194, N295, S368 UNIPROT:Q28193
MER0000384 Bos taurus 797 131-421 D153, H194, N295, S368 UNIPROT:Q28193
MER0000384 Bos taurus 797 131-421 D153, H194, N295, S368 UNIPROT:Q28193
MER0579743 Bubalus bubalis 797 131-421 D153, H194, N295, S368 GENBANK:XP_006058332
MER0325113 Callithrix jacchus 795 114-421 D153, H194, N295, S368 UNIPROT:U3FS81
MER0325113 Callithrix jacchus 795 114-421 D153, H194, N295, S368 UNIPROT:U3FS81
MER0677531 Camelus dromedarius 793 130-420 D152, H193, N294, S367, GENBANK:XP_010985078
MER0513011 Camelus ferus 796 130-420 D152, H193, N294, S367 GENBANK:XP_006192660
MER0053691 Canis lupus familiaris 814 122-397 D153, H194, N308, S381 GENBANK:XP_545864
MER0271054 Cavia porcellus 796 114-421 D153, H194, N295, S368 UNIPROT:H0VCV1
MER0271054 Cavia porcellus 796 114-421 D153, H194, N295, S368 UNIPROT:H0VCV1
MER0530925 Ceratotherium simum 793 131-421 D153, H194, N295, S368 GENBANK:XP_004432029
MER0587989 Cercopithecus sabaeus 794 131-421 D153, H194, N295, S368 GENBANK:XP_007988648
MER0591109 Chelonia mydas 787 132-422 D154, H195, N296, S369 GENBANK:XP_007059587
MER0584361 Chinchilla lanigera 796 131-421 D153, H194, N295, S368 GENBANK:XP_005381565
MER0577400 Chrysemys picta 787 132-422 D154, H195, N296, S369 GENBANK:XP_005300705
MER0575913 Chrysochloris asiatica 794 131-421 D153, H194, N295, S368 GENBANK:XP_006867209
MER0670029 Colobus angolensis 794 131-421 D153, H194, N295, S368 GENBANK:XP_011803654
MER0325118 Cricetulus griseus 794 114-421 D153, H194, N295, S368 UNIPROT:Q60426
MER0325118 Cricetulus griseus 794 114-421 D153, H194, N295, S368 UNIPROT:Q60426
MER0001557 Cricetulus longicaudatus 794 131-421 D153, H194, N295, S368 UNIPROT:Q60426
MER0001557 Cricetulus longicaudatus 794 131-421 D153, H194, N295, S368 UNIPROT:Q60426
MER0605621 Dasypus novemcinctus 710 44-334 D66, H107, N208, S281 GENBANK:XP_004479710
MER0107220 Echinops telfairi 792 131-421 D153, H194, N295, S368 GENBANK:XP_004708271
MER0564785 Elephantulus edwardii 794 131-421 D153, H194, N295, S368 GENBANK:XP_006885215
MER0563450 Eptesicus fuscus 794 131-421 D153, H194, N295, S368 GENBANK:XP_008158267
MER0098774 Equus caballus 793 131-421 D153, H194, N295, S368 GENBANK:XP_001502775
MER0560896 Equus przewalskii 795 131-421 D153, H194, N295, S368 GENBANK:XP_008510864
MER0615476 Erinaceus europaeus 795 131-421 D153, H194, N295, S368 GENBANK:XP_007538282
MER0610990 Felis catus 793 131-421 D153, H194, N295, S368 UNIPROT:M3W594
MER0610990 Felis catus 793 131-421 D153, H194, N295, S368 UNIPROT:M3W594
MER0655476 Fukomys damarensis 808 131-421 D153, H194, N295, S368 GENBANK:XP_010619400
MER0558535 Galeopterus variegatus 794 131-421 D153, H194, N295, S368 GENBANK:XP_008563303
MER0002053 Gallus gallus 789 123-423 D154, H195, N296, S369 GENBANK:CAA92109
MER0002053 Gallus gallus 789 123-423 D154, H195, N296, S369 GENBANK:CAA92109
MER0607502 Gorilla gorilla 794 131-421 D153, H194, N295, S368 GENBANK:XP_004056820
MER0325119 Heterocephalus glaber 792 114-421 D153, H194, N295, S368 GENBANK:EHB18478
MER0000375 Homo sapiens 794 131-421 D153, H194, N295, S368 GENBANK:NP_002560
MER0000375 Homo sapiens 794 131-421 D153, H194, N295, S368 GENBANK:NP_002560
MER0000375 Homo sapiens 794 131-421 D153, H194, N295, S368 GENBANK:NP_002560
MER0106683 Ictidomys tridecemlineatus 794 131-421 D153, H194, N295, S368 UNIPROT:I3MNM3
MER0106683 Ictidomys tridecemlineatus 794 131-421 D153, H194, N295, S368 UNIPROT:I3MNM3
MER0548452 Jaculus jaculus 794 131-421 D153, H194, N295, S368 GENBANK:XP_004658260
MER0548506 Lipotes vexillifer 792 131-421 D153, H194, N295, S368 GENBANK:XP_007470618
MER0102917 Loxodonta africana 802 114-421 D153, H194, N295, S368 GENBANK:XP_003413924
MER0603484 Macaca fascicularis 794 131-421 D153, H194, N295, S368 GENBANK:XP_005595532
MER0077102 Macaca mulatta 794 131-421 D153, H194, N295, S368 UNIPROT:G7MVY8
MER0077102 Macaca mulatta 794 131-421 D153, H194, N295, S368 UNIPROT:G7MVY8
MER0645240 Mandrillus leucophaeus 794 131-421 D153, H194, N295, S368 GENBANK:XP_011833762
MER0325111 Meleagris gallopavo 716 115-420 D154, H195, N296, S369 GENBANK:XP_003209667
MER0544409 Mesocricetus auratus 794 131-421 D153, H194, N295, S368 GENBANK:XP_005077869
MER0538379 Microtus ochrogaster 794 131-421 D153, H194, N295, S368 GENBANK:XP_005357706
MER0171292 Monodelphis domestica 780 120-420 D151, H192, N293, S366 GENBANK:XP_001368739
MER0000378 Mus musculus 793 131-421 D153, H194, N295, S368 GENBANK:NP_035176
MER0000378 Mus musculus 793 131-421 D153, H194, N295, S368 GENBANK:NP_035176
MER0000378 Mus musculus 793 131-421 D153, H194, N295, S368 GENBANK:NP_035176
MER0601793 Mustela putorius 796 132-422 D154, H195, N296, S369 GENBANK:XP_004763758
MER0613417 Myotis davidii 716 131-421 D153, H194, N295, S368 GENBANK:XP_006769667
MER0641524 Nannospalax galili 794 131-421 D153, H194, N295, S368 GENBANK:XP_008850996
MER0256835 Nomascus leucogenys 756 114-421 D153, H194, N295, S368 GENBANK:XP_003268605
MER0533137 Octodon degus 794 131-421 D153, H194, N295, S368 GENBANK:XP_004623373
MER0530901 Odobenus rosmarus 792 130-420 D152, H193, N294, S367 GENBANK:XP_004398331
MER0529828 Orcinus orca 792 131-421 D153, H194, N295, S368 GENBANK:XP_004278331
MER0325373 Ornithorhynchus anatinus 105 1-104 missing, missing, N15, S88 GENBANK:XP_003429873
MER0528192 Orycteropus afer 793 131-421 D153, H194, N295, S368 GENBANK:XP_007943332
MER0010955 Oryctolagus cuniculus 599 114-421 D153, H194, N295, S368 GENBANK:XP_002721548
MER0403211 Otolemur garnettii 794 131-421 D153, H194, N295, S368 GENBANK:XP_003803132
MER0140493 Ovis aries 794 131-421 D153, H194, N295, S368 UNIPROT:Q3BKJ1
MER0140493 Ovis aries 794 131-421 D153, H194, N295, S368 UNIPROT:Q3BKJ1
MER0409767 Pan paniscus 794 131-421 D153, H194, N295, S368 GENBANK:XP_003807767
MER0519214 Panthera tigris 772 110-400 D132, H173, N274, S347 GENBANK:XP_007078340
MER0526480 Papio anubis 794 131-421 D153, H194, N295, S368 UNIPROT:A0A096NK79
MER0526480 Papio anubis 794 131-421 D153, H194, N295, S368 UNIPROT:A0A096NK79
MER0520393 Physeter catodon 798 131-421 D153, H194, N295, S368 GENBANK:XP_007108404
MER0629502 Picoides pubescens 789 132-422 D154, H195, N296, S369 GENBANK:XP_009895595
MER0515806 Pteropus alecto 794 131-421 D153, H194, N295, S368 GENBANK:XP_006905347
MER0594669 Pteropus vampyrus 794 131-421 D153, H194, N295, S368 GENBANK:XP_011374454
MER0000385 Rattus norvegicus 793 131-421 D153, H194, N295, S368 PIR:KXRTF
MER0000385 Rattus norvegicus 793 131-421 D153, H194, N295, S368 PIR:KXRTF
MER0570834 Rhinopithecus roxellana 794 131-421 D153, H194, N295, S368 GENBANK:XP_010383092
MER0512726 Saimiri boliviensis 794 131-421 D153, H194, N295, S368 GENBANK:XP_003921646
MER0403220 Sarcophilus harrisii 780 129-419 D151, H192, N293, S366 GENBANK:XP_003755557
MER0597301 Sorex araneus 793 131-421 D153, H194, N295, S368 GENBANK:XP_004617631
MER0165701 Sus scrofa 797 131-421 D153, H194, N295, S368 UNIPROT:F1RMJ1
MER0165701 Sus scrofa 797 131-421 D153, H194, N295, S368 UNIPROT:F1RMJ1
MER0227664 Taeniopygia guttata 726 109-372 missing, H130, N231, S304 GENBANK:XP_002187670
MER0596692 Tarsius syrichta 794 131-421 D153, H194, N295, S368 GENBANK:XP_008048435
MER0485222 Trichechus manatus 796 131-421 D153, H194, N295, S368 GENBANK:XP_004370709
MER0597698 Tupaia chinensis 802 131-421 D153, H194, N295, S368 UNIPROT:L9KJ91
MER0597698 Tupaia chinensis 802 131-421 D153, H194, N295, S368 UNIPROT:L9KJ91
MER0616912 Vicugna pacos 794 131-421 D153, H194, N295, S368 GENBANK:XP_006198491
MER0000372 Xenopus laevis 785 129-419 D151, H192, N293, S366 UNIPROT:Q5XHG7
MER0000372 Xenopus laevis 785 129-419 D151, H192, N293, S366 UNIPROT:Q5XHG7
MER0000372 Xenopus laevis 785 129-419 D151, H192, N293, S366 UNIPROT:Q5XHG7
MER0000372 Xenopus laevis 785 129-419 D151, H192, N293, S366 UNIPROT:Q5XHG7
MER0325110 Xenopus tropicalis 784 128-418 D150, H191, N292, S365 GENBANK:XP_002932287

feedback
Page created 8-September-2023

EMBL-EBI logo

© 2025 EBI
Terms of use