Sequence features for peptidase S01.231: urokinase-type plasminogen activator

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

MERNUM	Species	Sequence length	Peptidase unit	Active site residues	Source
MER0210600	Ailuropoda melanoleuca	432	180-427	H225, D276, S377	UNIPROT:G1ME57
MER0210600	Ailuropoda melanoleuca	432	180-427	H225, D276, S377	UNIPROT:G1ME57
MER0327512	Anas platyrhynchos	437	176-422	H220, D275, S376	GENBANK:XP_005015757
MER0367312	Anolis carolinensis	431	174-419	H220, D272, S372	GENBANK:XP_003223189
MER0556904	Astatotilapia burtoni	387	132-373	H173, D225, S326	GENBANK:XP_005950211
MER0387422	Balaenoptera acutorostrata	431	179-422	H224, D275, S376	GENBANK:XP_007166644
MER0385702	Bos grunniens	433	181-421	H226, D277, S378	GENBANK:ELR52237
MER0000198	Bos taurus	433	181-428	H226, D277, S378	UNIPROT:Q9TVA8
MER0000198	Bos taurus	433	181-428	H226, D277, S378	UNIPROT:Q9TVA8
MER0000198	Bos taurus	433	181-428	H226, D277, S378	UNIPROT:Q9TVA8
MER0580533	Bubalus bubalis	433	181-428	H226, D277, S378	GENBANK:XP_006052709
MER0580534	Bubalus bubalis	483	227-478	H272, D327, S428	GENBANK:XP_006052706
MER0366028	Callithrix jacchus	430	178-420	H223, D274, S375	UNIPROT:F7HXM8
MER0366028	Callithrix jacchus	430	178-420	H223, D274, S375	UNIPROT:F7HXM8
MER0581603	Calypte anna	432	172-417	H216, D270, S371	GENBANK:XP_008502226
MER0441865	Camelus ferus	433	181-428	H226, D277, S378	GENBANK:XP_006173476
MER0555923	Capra hircus	433	181-428	H226, D277, S378	GENBANK:XP_005699278
MER0103378	Cavia porcellus	434	355-610	G400, ?451, ?553	GENBANK:XP_003473653
MER0541326	Ceratotherium simum	433	181-428	H226, D277, S378	GENBANK:XP_004427008
MER0584917	Cercopithecus sabaeus	431	179-426	H224, D275, S376	GENBANK:XP_007961156
MER0591894	Chelonia mydas	438	180-427	H226, D278, S379	GENBANK:XP_007057550
MER0579551	Chinchilla lanigera	453	201-448	H246, D297, S398	GENBANK:XP_005389993
MER0577590	Chrysemys picta	438	180-427	H226, D278, S379	GENBANK:XP_005278798
MER0575092	Chrysochloris asiatica	432	179-426	H224, D275, S376	GENBANK:XP_006835979
MER0382803	Columba livia	433	172-421	H216, D271, S372	GENBANK:EMC79939
MER0574356	Condylura cristata	434	181-429	H226, D278, S379	GENBANK:XP_004681118
MER0572208	Corvus brachyrhynchos	432	171-417	H215, D270, S371	GENBANK:XP_008641077
MER0365847	Cricetulus griseus	397	144-386	H190, D241, S342	UNIPROT:G3GWP9
MER0365847	Cricetulus griseus	397	144-386	H190, D241, S342	UNIPROT:G3GWP9
MER0365882	Cricetulus griseus	433	180-426	H226, D277, S378	GENBANK:XP_003496775
MER0567199	Cynoglossus semilaevis	432	173-420	H218, D272, S373	GENBANK:XP_008313408
MER0568037	Cynoglossus semilaevis	391	138-376	H178, D230, S329	GENBANK:XP_008320247
MER0090530	Danio rerio	432	125-422	H224, D278, S379	GENBANK:XP_001346717
MER0163793	Danio rerio	402	91-383	H185, D239, S340	GENBANK:NP_001165872
MER0102795	Dasypus novemcinctus	432	179-426	H224, D275, S376	GENBANK:XP_004473839
MER0564954	Elephantulus edwardii	447	193-441	H238, D290, S391	GENBANK:XP_006887626
MER0563834	Eptesicus fuscus	439	187-434	H232, D283, S384	GENBANK:XP_008143586
MER0039081	Equus caballus	103	1-103	H33, D84, missing	UNIPROT:Q95M89
MER0039081	Equus caballus	103	1-103	H33, D84, missing	UNIPROT:Q95M89
MER0098779	Equus caballus	433	181-428	H226, D277, S378	UNIPROT:F7BT48
MER0098779	Equus caballus	433	181-428	H226, D277, S378	UNIPROT:F7BT48
MER0560195	Falco cherrug	432	172-417	H216, D270, S371	GENBANK:XP_005443909
MER0545389	Falco peregrinus	432	172-417	H216, D270, S371	GENBANK:XP_005229802
MER0383037	Felis catus	433	181-423	H226, D277, S378	GENBANK:XP_003994153
MER0568776	Ficedula albicollis	431	170-415	H214, D269, S370	UNIPROT:U3JX40
MER0568776	Ficedula albicollis	431	170-415	H214, D269, S370	UNIPROT:U3JX40
MER0000201	Gallus gallus	434	173-423	H217, D272, S373	PIR:A35005
MER0000201	Gallus gallus	434	173-423	H217, D272, S373	PIR:A35005
MER0000201	Gallus gallus	434	173-423	H217, D272, S373	PIR:A35005
MER0000201	Gallus gallus	434	173-423	H217, D272, S373	PIR:A35005
MER0559179	Geospiza fortis	432	171-416	H215, D270, S371	GENBANK:XP_005417292
MER0383991	Gorilla gorilla	431	179-420	H224, D275, S376	UNIPROT:G3RGY4
MER0383991	Gorilla gorilla	431	179-420	H224, D275, S376	UNIPROT:G3RGY4
MER0486063	Heterocephalus glaber	570	179-565	H224, D275, S509	UNIPROT:G5C7I1
MER0486063	Heterocephalus glaber	570	179-565	H224, D275, S509	UNIPROT:G5C7I1
MER0552054	Heterocephalus glaber	437	179-432	H224, D275, S376	GENBANK:XP_004846370
MER0000195	Homo sapiens	431	179-431	H224, D275, S376	PIR:S65783
MER0000195	Homo sapiens	431	179-431	H224, D275, S376	PIR:S65783
MER0552077	Leptonychotes weddellii	427	175-422	H220, D271, S372	GENBANK:XP_006733513
MER0258566	Loxodonta africana	416	162-403	H207, D259, S360	GENBANK:XP_003408954
MER0365777	Macaca fascicularis	431	179-420	H224, D275, S376	UNIPROT:G7PF00
MER0365777	Macaca fascicularis	431	179-420	H224, D275, S376	UNIPROT:G7PF00
MER0077903	Macaca mulatta	431	179-420	H224, D275, S376	UNIPROT:G7N249
MER0077903	Macaca mulatta	431	179-420	H224, D275, S376	UNIPROT:G7N249
MER0543684	Maylandia zebra	387	132-373	H173, D225, S326	GENBANK:XP_004555963
MER0366137	Meleagris gallopavo	434	173-422	H217, D272, S373	UNIPROT:G1N3G3
MER0366137	Meleagris gallopavo	434	173-422	H217, D272, S373	UNIPROT:G1N3G3
MER0544795	Mesocricetus auratus	433	180-428	H226, D277, S378	GENBANK:XP_005083594
MER0538923	Microtus ochrogaster	437	184-432	H230, D281, S382	GENBANK:XP_005367711
MER0366429	Monodelphis domestica	444	224-435	H239, D290, S391	GENBANK:XP_003340014
MER0000199	Mus musculus	433	180-428	H226, D277, S378	PIR:UKMS
MER0000199	Mus musculus	433	180-428	H226, D277, S378	PIR:UKMS
MER0366082	Mustela putorius	432	180-421	H225, D276, S377	GENBANK:AES04176
MER0563349	Myotis brandtii	439	187-434	H232, D283, S384	GENBANK:XP_005864721
MER0386613	Myotis davidii	636	384-625	H429, D480, S581	UNIPROT:L5M241
MER0386613	Myotis davidii	636	384-625	H429, D480, S581	UNIPROT:L5M241
MER0535033	Neolamprologus brichardi	387	132-373	H173, D225, S326	GENBANK:XP_006800769
MER0256762	Nomascus leucogenys	345	93-334	H138, D189, S290	GENBANK:XP_003271313
MER0533750	Ochotona princeps	435	183-430	H228, D279, S380	GENBANK:XP_004583665
MER0533167	Octodon degus	434	180-429	H225, D278, S379	GENBANK:XP_004624442
MER0531426	Odobenus rosmarus	427	175-422	H220, D271, S372	GENBANK:XP_004407091
MER0365724	Ogataea parapolymorpha	297	45-286	H90, D141, S242	GENBANK:EFW96375
MER0485420	Oikopleura dioica	723	373-506	missing, missing, S456	UNIPROT:E4XJ32
MER0485420	Oikopleura dioica	723	373-506	missing, missing, S456	UNIPROT:E4XJ32
MER0485506	Oikopleura dioica	450	91-217	missing, missing, S174	UNIPROT:E4Y4S0
MER0485506	Oikopleura dioica	450	91-217	missing, missing, S174	UNIPROT:E4Y4S0
MER0529570	Orcinus orca	413	161-408	H206, D257, S358	GENBANK:XP_004273141
MER0366185	Oreochromis niloticus	386	131-368	H172, D224, S325	GENBANK:XP_003441160
MER0367567	Oreochromis niloticus	420	159-404	H204, D258, S359	GENBANK:XP_003448745
MER0097802	Ornithorhynchus anatinus	432	176-418	H220, D269, S370	GENBANK:XP_001510562
MER0527955	Orycteropus afer	436	181-430	H226, D277, S380	GENBANK:XP_007938789
MER0016646	Oryctolagus cuniculus	128	1-128	H33, D84, missing	UNIPROT:O97587
MER0016646	Oryctolagus cuniculus	128	1-128	H33, D84, missing	UNIPROT:O97587
MER0024909	Oryctolagus cuniculus	433	181-428	H226, D277, S378	GENBANK:AAM83187
MER0024909	Oryctolagus cuniculus	433	181-428	H226, D277, S378	GENBANK:AAM83187
MER0024909	Oryctolagus cuniculus	433	181-428	H226, D277, S378	GENBANK:AAM83187
MER0110986	Oryzias latipes	388	136-375	H176, D226, S327	GENBANK:XP_004077457
MER0111162	Oryzias latipes	453	192-437	H237, D291, S392	GENBANK:NP_001188454
MER0256219	Otolemur garnettii	429	179-423	H224, D275, S376	UNIPROT:H0XH31
MER0256219	Otolemur garnettii	429	179-423	H224, D275, S376	UNIPROT:H0XH31
MER0210570	Ovis aries	433	181-428	H226, D277, S378	GENBANK:NP_001157065
MER0365879	Pan paniscus	431	179-420	H224, D275, S376	GENBANK:XP_003813039
MER0365762	Pan troglodytes	490	238-479	H283, D334, S435	GENBANK:XP_003312681
MER0518495	Panthera tigris	441	189-436	H234, D285, S386	GENBANK:XP_007095715
MER0518005	Pantholops hodgsonii	431	181-428	H226, D277, S378	GENBANK:XP_005968510
MER0384581	Papio anubis	433	178-422	H223, D274, S378	UNIPROT:A0A096P4K5
MER0384581	Papio anubis	433	178-422	H223, D274, S378	UNIPROT:A0A096P4K5
MER0000196	Papio cynocephalus	433	178-428	H223, D274, S378	PIR:UKBAY
MER0000196	Papio cynocephalus	433	178-428	H223, D274, S378	PIR:UKBAY
MER0524688	Pelodiscus sinensis	440	180-428	H226, D278, S379	UNIPROT:K7FEG8
MER0524688	Pelodiscus sinensis	440	180-428	H226, D278, S379	UNIPROT:K7FEG8
MER0521318	Physeter catodon	430	179-421	H224, D274, S375	GENBANK:XP_007114404
MER0522835	Poecilia formosa	473	212-459	H257, D311, S412	UNIPROT:A0A087Y430
MER0522835	Poecilia formosa	473	212-459	H257, D311, S412	UNIPROT:A0A087Y430
MER0522937	Poecilia formosa	390	137-376	H176, D228, S329	GENBANK:XP_007546166
MER0513353	Poecilia reticulata	467	206-453	H251, D305, S406	GENBANK:XP_008435407
MER0513479	Poecilia reticulata	388	135-374	H174, D226, S327	GENBANK:XP_008427980
MER0365933	Pongo abelii	431	179-420	H224, D275, S376	UNIPROT:Q5RF29
MER0365933	Pongo abelii	431	179-420	H224, D275, S376	UNIPROT:Q5RF29
MER0109531	Pongo pygmaeus	431	179-426	H224, D275, S376	UNIPROT:Q5RF29
MER0109531	Pongo pygmaeus	431	179-426	H224, D275, S376	UNIPROT:Q5RF29
MER0109531	Pongo pygmaeus	431	179-426	H224, D275, S376	UNIPROT:Q5RF29
MER0383112	Pteropus alecto	433	181-422	H226, D277, S378	GENBANK:ELK09524
MER0438497	Python bivittatus	324	71-311	H113, D165, S265	GENBANK:XP_007442899
MER0000200	Rattus norvegicus	432	179-427	H225, D276, S377	PIR:S18932
MER0000200	Rattus norvegicus	432	179-427	H225, D276, S377	PIR:S18932
MER0383141	Saimiri boliviensis	430	178-420	H223, D274, S375	GENBANK:XP_003939843
MER0366587	Sarcophilus harrisii	436	216-427	H231, D282, S383	GENBANK:XP_003755157
MER0000197	Sus scrofa	442	190-437	H235, D286, S387	PIR:UKPG
MER0000197	Sus scrofa	442	190-437	H235, D286, S387	PIR:UKPG
MER0366502	Taeniopygia guttata	432	171-418	H215, D270, S371	GENBANK:XP_002193229
MER0384943	Takifugu rubripes	319	69-301	H108, D160, S258	GENBANK:XP_003964205
MER0387667	Takifugu rubripes	473	219-466	H264, D318, S417	GENBANK:XP_003961151
MER0596113	Tarsius syrichta	433	181-428	H226, D277, S378	GENBANK:XP_008067149
MER0099115	Tetraodon nigroviridis	230	2-229	H42, D90, S186	UNIPROT:Q4RQD7
MER0099115	Tetraodon nigroviridis	230	2-229	H42, D90, S186	UNIPROT:Q4RQD7
MER0480350	Trichechus manatus	415	162-409	H207, D258, S359	GENBANK:XP_004383273
MER0384738	Tupaia chinensis	453	201-442	H246, D297, S398	GENBANK:ELV10065
MER0616588	Vicugna pacos	433	181-428	H226, D277, S378,	GENBANK:XP_006218942
MER0450779	Xiphophorus maculatus	369	116-355	H155, D207, S308	GENBANK:XP_005811960
MER0451917	Xiphophorus maculatus	282	21-268	H66, D120, S221	GENBANK:XP_005794736
MER0447025	Zonotrichia albicollis	432	171-416	H215, D270, S371	GENBANK:XP_005481521