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Literature for peptidase T01.011: proteasome subunit beta2c

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, A Assay, T Target, P Specificity, V Review, M Mutation, I Inhibitor, L Localization. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. Maurits,E., Degeling,C.G., Kisselev,A.F., Florea,B.I. and Overkleeft,H.S.
    Structure-Based Design of Fluorogenic Substrates Selective for Human Proteasome Subunits
    Chembiochem PubMed  Europe PubMed DOI
  2. Tsimokha,A.S., Artamonova,T.O., Diakonov,E.E., Khodorkovskii,M.A. and Tomilin,A.N.
    Post-Translational Modifications of Extracellular Proteasome
    Molecules25, PubMed  Europe PubMed DOI
  3. Wysocka,M., Romanowska,A., Gruba,N., Michalska,M., Gieldon,A. and Lesner,A.
    A peptidomimetic fluorescent probe to detect the trypsin beta2 subunit of the human 20S proteasome
    Int J Mol Sci21, PubMed  Europe PubMed DOI  A
    4. 2019
  4. Besse,A., Besse,L., Kraus,M., Mendez-Lopez,M., Bader,J., Xin,B.T., de Bruin,G., Maurits,E., Overkleeft,H.S. and Driessen,C.
    Proteasome Inhibition in Multiple Myeloma: Head-to-Head Comparison of Currently Available Proteasome Inhibitors
    Cell Chem Biol26, 340-351. PubMed  Europe PubMed DOI  I
  5. Steverding,D., Florea,B.I. and Overkleeft,H.S.
    Trypanosoma brucei: beta2-selective proteasome inhibitors do not block the proteasomal trypsin-like activity but are trypanocidal
    Mol Biochem Parasitol227, 1-4. PubMed  Europe PubMed DOI  I
  6. Xin,B.T., Huber,E.M., de Bruin,G., Heinemeyer,W., Maurits,E., Espinal,C., Du,Y., Janssens,M., Weyburne,E.S., Kisselev,A.F., Florea,B.I., Driessen,C., van der Marel,G.A., Groll,M. and Overkleeft,H.S.
    Structure-based design of inhibitors selective for human proteasome beta2c or beta2i subunits
    J Med Chem62, 1626-1642. PubMed  Europe PubMed DOI  I
    7. 2018
  7. Artschwager,R., Ward,D.J., Gannon,S., Brouwer,A.J., van de Langemheen,H., Kowalski,H. and Liskamp,R.M.J.
    Potent and highly selective inhibitors of the proteasome trypsin-like site by incorporation of basic side chain containing amino acid derived sulfonyl fluorides
    J Med Chem61, 5395-5411. PubMed  Europe PubMed DOI  I
  8. Pierce,M.R., Bakas,N.A., Pirrung,M.C. and Bachmann,A.S.
    Thiasyrbactins induce cell death via proteasome inhibition in multiple myeloma cells
    Anticancer Res38, 5607-5613. PubMed  Europe PubMed DOI  I
    9. 2017
  9. Hewings,D.S., Flygare,J.A., Wertz,I.E. and Bogyo,M.
    Activity-based probes for the multicatalytic proteasome
    FEBS J284, 1540-1554. PubMed  Europe PubMed DOI  V  L  I
  10. Misas-Villamil,J.C., van der Burgh,A.M., Grosse-Holz,F., Bach-Pages,M., Kovacs,J., Kaschani,F., Schilasky,S., Emon,A.E., Ruben,M., Kaiser,M., Overkleeft,H.S. and Van Der Hoorn,R.A.
    Subunit-selective proteasome activity profiling uncovers uncoupled proteasome subunit activities during bacterial infections
    Plant J90, 418-430. PubMed  Europe PubMed DOI
  11. Rolfe,M.
    The holy grail: solid tumor efficacy by proteasome inhibition
    Cell Chem Biol24, 125-126. PubMed  Europe PubMed DOI  T  I
  12. Weyburne,E.S., Wilkins,O.M., Sha,Z., Williams,D.A., Pletnev,A.A., de Bruin,G., Overkleeft,H.S., Goldberg,A.L., Cole,M.D. and Kisselev,A.F.
    Inhibition of the proteasome beta2 site sensitizes triple-negative breast cancer cells to beta5 inhibitors and suppresses Nrf1 activation
    Cell Chem Biol24, 218-230. PubMed  Europe PubMed DOI  T  I
    13. 2016
  13. de Bruin,G., Xin,B.T., Kraus,M., van der Stelt,M., van der Marel,G.A., Kisselev,A.F., Driessen,C., Florea,B.I. and Overkleeft,H.S.
    A set of activity-based probes to visualize human (immuno)proteasome activities
    Angew Chem Int Ed Engl55, 4199-4203. PubMed  Europe PubMed DOI  A  I
  14. Gruba,N., Wysocka,M., Brzezinska,M., Debowski,D., Rolka,K., Martin,N.I. and Lesner,A.
    Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome
    Anal Biochem508, 38-45. PubMed  Europe PubMed DOI  A  P
  15. Rut,W. and Drag,M.
    Human 20S proteasome activity towards fluorogenic peptides of various chain lengths
    Biol Chem397, 921-926. PubMed  Europe PubMed DOI  P
  16. Zhou,T., Cai,Y., Liang,L., Yang,L., Xu,F., Niu,Y., Wang,C., Zhang,J.L. and Xu,P.
    Discovery of a potent and highly specific beta2 proteasome inhibitor from a library of copper complexes
    Bioorg Med Chem Lett26, 5780-5784. PubMed  Europe PubMed DOI  I
    17. 2015
  17. Huber,E.M., Heinemeyer,W. and Groll,M.
    Bortezomib-resistant mutant proteasomes: structural and biochemical evaluation with carfilzomib and ONX 0914
    Structure23, 407-417. PubMed  Europe PubMed DOI  S  I
  18. Huber,E.M., de Bruin,G., Heinemeyer,W., Paniagua Soriano,G., Overkleeft,H.S. and Groll,M.
    Systematic analyses of substrate preferences of 20S proteasomes using peptidic epoxyketone inhibitors
    J Am Chem Soc137, 7835-7842. PubMed  Europe PubMed DOI  P  S  I
  19. Koroleva,O.N., Pham,T.H., Bouvier,D., Dufau,L., Qin,L., Reboud-Ravaux,M., Ivanov,A.A., Zhuze,A.L., Gromova,E.S. and Bouvier-Durand,M.
    Bisbenzimidazole derivatives as potent inhibitors of the trypsin-like sites of the immunoproteasome core particle
    Biochimie108C, 94-100. PubMed  Europe PubMed DOI  I
  20. Kraus,J., Kraus,M., Liu,N., Besse,L., Bader,J., Geurink,P.P., de Bruin,G., Kisselev,A.F., Overkleeft,H. and Driessen,C.
    The novel beta2-selective proteasome inhibitor LU-102 decreases phosphorylation of I kappa B and induces highly synergistic cytotoxicity in combination with ibrutinib in multiple myeloma cells
    Cancer Chemother Pharmacol76, 383-396. PubMed  Europe PubMed DOI  I
  21. Kraus,M., Bader,J., Geurink,P.P., Weyburne,E.S., Mirabella,A.C., Silzle,T., Shabaneh,T.B., van der Linden,W.A., de Bruin,G., Haile,S.R., van Rooden,E., Appenzeller,C., Li,N., Kisselev,A.F., Overkleeft,H. and Driessen,C.
    The novel beta2-selective proteasome inhibitor LU-102 synergizes with bortezomib and carfilzomib to overcome proteasome inhibitor resistance of myeloma cells
    Haematologica100, 1350-1360. PubMed  Europe PubMed DOI  I
  22. O'Brien,M.A., Moravec,R.A., Riss,T.L. and Bulleit,R.F.
    Homogeneous, bioluminescent proteasome assays
    Methods Mol Biol1219, 95-114. PubMed  Europe PubMed DOI  A
  23. Yang,W., Li,L., Liu,R., Sun,G., Liu,C., Zhang,S., Jiang,P., Zhang,X., Ren,H., Wang,Z. and Cui,J.
    Molecular identification and characterization of Trichinella spiralis proteasome subunit beta type-7
    Parasit Vectors8, 18-18. PubMed  Europe PubMed DOI
  24. Zhu,Z., Zhang,L. and Shi,G.
    Proteasome as a molecular target of microcystin-LR
    Toxins (Basel)7, 2221-2231. PubMed  Europe PubMed DOI  I
    25. 2014
  25. Loizidou,E.Z. and Zeinalipour-Yazdi,C.D.
    Computational inhibition studies of the human proteasome by argyrin-based analogues with subunit specificity
    Chem Biol Drug Des84, 99-107. PubMed  Europe PubMed DOI  I
  26. Wilkins,O.M., Downey,S.L., Weyburne,E.S., Williams,D.A., Mirabella,A.C., Overkleeft,H.S. and Kisselev,A.F.
    Cell-line-specific high background in the Proteasome-Glo assay of proteasome trypsin-like activity
    Anal Biochem451, 1-3. PubMed  Europe PubMed DOI  A
    27. 2013
  27. Geurink,P.P., van der Linden,W.A., Mirabella,A.C., Gallastegui,N., de Bruin,G., Blom,A.E., Voges,M.J., Mock,E.D., Florea,B.I., van der Marel,G.A., Driessen,C., van der Stelt,M., Groll,M., Overkleeft,H.S. and Kisselev,A.F.
    Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites
    J Med Chem56, 1262-1275. PubMed  Europe PubMed DOI  I
  28. Gotze,S., Bose,A., Abele,D., Sokolova,I.M. and Saborowski,R.
    Pitfalls in invertebrate proteasome assays
    J Exp Biol216, 1351-1354. PubMed  Europe PubMed DOI  A  I
    29. 2012
  29. de Jong,A., Schuurman,K.G., Rodenko,B., Ovaa,H. and Berkers,C.R.
    Fluorescence-based proteasome activity profiling
    Methods Mol Biol803, 183-204. PubMed  Europe PubMed DOI  A
  30. Grawert,M.A. and Groll,M.
    Eukaryotic 20S proteasome
    [ISSN:978-0-12-407742-3]3, 3684-3691. DOI
  31. Pereira,A.R., Kale,A.J., Fenley,A.T., Byrum,T., Debonsi,H.M., Gilson,M.K., Valeriote,F.A., Moore,B.S. and Gerwick,W.H.
    The carmaphycins: new proteasome inhibitors exhibiting an alpha,beta-epoxyketone warhead from a marine cyanobacterium
    Chembiochem13, 810-817. PubMed  Europe PubMed DOI  I
    32. 2011
  32. Clark,L.A., Tsai,K.L., Starr,A.N., Nowend,K.L. and Murphy,K.E.
    A missense mutation in the 20S proteasome beta2 subunit of Great Danes having harlequin coat patterning
    Genomics97, 244-248. PubMed  Europe PubMed DOI  M
  33. Collavoli,A., Comelli,L., Cervelli,T. and Galli,A.
    The over-expression of the beta2 catalytic subunit of the proteasome decreases homologous recombination and impairs DNA double-strand break repair in human cells
    J Biomed Biotechnol2011, 757960-757960. PubMed  Europe PubMed DOI
  34. Mirabella,A.C., Pletnev,A.A., Downey,S.L., Florea,B.I., Shabaneh,T.B., Britton,M., Verdoes,M., Filippov,D.V., Overkleeft,H.S. and Kisselev,A.F.
    Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib
    Chem Biol18, 608-618. PubMed  Europe PubMed DOI  I
    35. 2010
  35. Geurink,P.P., Florea,B.I., van der Marel,G.A., Kessler,B.M. and Overkleeft,H.S.
    Probing the proteasome cavity in three steps: bio-orthogonal photo-reactive suicide substrates
    Chem Commun (Camb)46, 9052-9054. PubMed  Europe PubMed DOI
  36. Liggett,A., Crawford,L.J., Walker,B., Morris,T.C. and Irvine,A.E.
    Methods for measuring proteasome activity: current limitations and future developments
    Leuk Res34, 1403-1409. PubMed  Europe PubMed DOI  A
  37. Screen,M., Britton,M., Downey,S.L., Verdoes,M., Voges,M.J., Blom,A.E., Geurink,P.P., Risseeuw,M.D., Florea,B.I., van der Linden,W.A., Pletnev,A.A., Overkleeft,H.S. and Kisselev,A.F.
    Nature of pharmacophore influences active site specificity of proteasome inhibitors
    J Biol Chem285, 40125-40134. PubMed  Europe PubMed DOI  I
  38. Wu,Y.X. and Fang,X.
    Apigenin, chrysin, and luteolin selectively inhibit chymotrypsin-like and trypsin-like proteasome catalytic activities in tumor cells
    Planta Med76, 128-132. PubMed  Europe PubMed DOI  I
    39. 2009
  39. Britton,M., Lucas,M.M., Downey,S.L., Screen,M., Pletnev,A.A., Verdoes,M., Tokhunts,R.A., Amir,O., Goddard,A.L., Pelphrey,P.M., Wright,D.L., Overkleeft,H.S. and Kisselev,A.F.
    Selective inhibitor of proteasome's caspase-like sites sensitizes cells to specific inhibition of chymotrypsin-like sites
    Chem Biol16, 1278-1289. PubMed  Europe PubMed DOI  I
  40. Moravec,R.A., O'Brien,M.A., Daily,W.J., Scurria,M.A., Bernad,L. and Riss,T.L.
    Cell-based bioluminescent assays for all three proteasome activities in a homogeneous format
    Anal Biochem387, 294-302. PubMed  Europe PubMed DOI  A
    41. 2008
  41. Baldisserotto,A., Marastoni,M., Lazzari,I., Trapella,C., Gavioli,R. and Tomatis,R.
    C-terminal constrained phenylalanine as a pharmacophoric unit in peptide-based proteasome inhibitors
    Eur J Med Chem43, 1403-1411. PubMed  Europe PubMed DOI  I
  42. Chouduri,A.U., Mishina,K., Shimizu,T., Yamazaki,M., Tokumoto,T. and Yamada,S.
    High affinity Zn2+ inhibitory site(s) for the trypsin-like peptidase of the 20S proteasome
    Arch Biochem Biophys477, 113-120. PubMed  Europe PubMed DOI
  43. Uttenweiler-Joseph,S., Claverol,S., Sylvius,L., Bousquet-Dubouch,M.P., Burlet-Schiltz,O. and Monsarrat,B.
    Toward a full characterization of the human 20S proteasome subunits and their isoforms by a combination of proteomic approaches
    Methods Mol Biol484, 111-130. PubMed  Europe PubMed DOI
    44. 2007
  44. Baldisserotto,A., Marastoni,M., Trapella,C., Gavioli,R., Ferretti,V., Pretto,L. and Tomatis,R.
    Glutamine vinyl ester proteasome inhibitors selective for trypsin-like (beta2) subunit
    Eur J Med Chem42, 586-592. PubMed  Europe PubMed DOI  I
  45. Miller,C.P., Ban,K., Dujka,M.E., McConkey,D.J., Munsell,M., Palladino,M. and Chandra,J.
    NPI-0052, a novel proteasome inhibitor, induces caspase-8 and ROS-dependent apoptosis alone and in combination with HDAC inhibitors in leukemia cells
    Blood110, 267-277. PubMed  Europe PubMed DOI  I
    46. 2006
  46. [YEAR:15-6-2006]Crawford,L.J., Walker,B., Ovaa,H., Chauhan,D., Anderson,K.C., Morris,T.C. and Irvine,A.E.
    Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132
    Cancer Res66, 6379-6386. PubMed  Europe PubMed DOI  I
  47. Groll,M., Gotz,M., Kaiser,M., Weyher,E. and Moroder,L.
    TMC-95-Based inhibitor design provides evidence for the catalytic versatility of the proteasome
    Chem Biol13, 607-614. PubMed  Europe PubMed DOI  I
  48. [YEAR:2-2-2006]Kisselev,A.F., Callard,A. and Goldberg,A.L.
    Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate
    J Biol Chem281, 8582-8590. PubMed  Europe PubMed DOI
  49. [YEAR:4-4-2006]Marastoni,M., Baldisserotto,A., Trapella,C., Gavioli,R. and Tomatis,R.
    P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors
    Bioorg Med Chem Lett16, 3125-3130. PubMed  Europe PubMed DOI  I
    50. 2005
  50. [YEAR:9-6-2005]Braun,H.A., Umbreen,S., Groll,M., Kuckelkorn,U., Mlynarczuk,I., Wigand,M.E., Drung,I., Kloetzel,P.M. and Schmidt,B.
    Tripeptide mimetics inhibit the 20 S proteasome by covalent bonding to the active threonines
    J Biol Chem280, 28394-28401. PubMed  Europe PubMed DOI  I
  51. Gaczynska,M. and Osmulski,P.A.
    Small-molecule inhibitors of proteasome activity
    Methods Mol Biol301, 3-22. PubMed  Europe PubMed DOI  I
  52. Kisselev,A.F. and Goldberg,A.L.
    Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates
    Methods Enzymol398, 364-378. PubMed  Europe PubMed DOI
  53. [YEAR:28-7-2005]Marastoni,M., Baldisserotto,A., Cellini,S., Gavioli,R. and Tomatis,R.
    Peptidyl vinyl ester derivatives: new class of selective inhibitors of proteasome trypsin-like activity
    J Med Chem48, 5038-5042. PubMed  Europe PubMed DOI  I
  54. Steverding,D., Spackman,R.W., Royle,H.J. and Glenn,R.J.
    Trypanocidal activities of trileucine methyl vinyl sulfone proteasome inhibitors
    Parasitol Res95, 73-76. PubMed  Europe PubMed DOI  I
    55. 2004
  55. [YEAR:29-11-2004]Groll,M. and Huber,R.
    Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach
    Biochim Biophys Acta1695, 33-44. PubMed  Europe PubMed DOI  V  I
  56. [YEAR:2-4-2004]Ramos,P.C., Marques,A.J., London,M.K. and Dohmen,R.J.
    Role of C-terminal extensions of subunits beta2 and beta7 in assembly and activity of eukaryotic proteasomes
    J Biol Chem279, 14323-14330. PubMed  Europe PubMed DOI
  57. Seemuller,E., Dolenc,I. and Lupas,A.
    Eukaryotic 20S proteasome
    [ISSN:0-12-079610-4]2, 2068-2077.  V
    58. 2002
  58. [YEAR:1-12-2002]Cardozo,C. and Michaud,C.
    Proteasome-mediated degradation of tau proteins occurs independently of the chymotrypsin-like activity by a nonprocessive pathway
    Arch Biochem Biophys408, 103-110. PubMed  Europe PubMed DOI
  59. Groll,M., Nazif,T., Huber,R. and Bogyo,M.
    Probing structural determinants distal to the site of hydrolysis that control substrate specificity of the 20S proteasome
    Chem Biol9, 655-662. PubMed  Europe PubMed DOI  S  I
  60. Unno,M., Mizushima,T., Morimoto,Y., Tomisugi,Y., Tanaka,K., Yasuoka,N. and Tsukihara,T.
    The structure of the mammalian 20S proteasome at 2.75 A resolution
    Structure10, 609-618. PubMed  Europe PubMed DOI  S
    61. 2001
  61. Kessler,B.M., Tortorella,D., Altun,M., Kisselev,A.F., Fiebiger,E., Hekking,B.G., Ploegh,H.L. and Overkleeft,H.S.
    Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits
    Chem Biol8, 913-929. PubMed  Europe PubMed DOI  I
  62. [YEAR:13-3-2001]Nazif,T. and Bogyo,M.
    Global analysis of proteasomal substrate specificity using positional-scanning libraries of covalent inhibitors
    Proc Natl Acad Sci U S A98, 2967-2972. PubMed  Europe PubMed DOI  I
  63. [YEAR:6-11-2001]Oberdorf,J., Carlson,E.J. and Skach,W.R.
    Redundancy of mammalian proteasome beta subunit function during endoplasmic reticulum associated degradation
    Biochemistry40, 13397-13405. PubMed  Europe PubMed DOI
    64. 2000
  64. [YEAR:19-5-2000]Kisselev,A.F., Songyang,Z. and Goldberg,A.L.
    Why does threonine, and not serine, function as the active site nucleophile in proteasomes?
    J Biol Chem275, 14831-14837. PubMed  Europe PubMed DOI  I
  65. Koguchi,Y., Kohno,J., Nishio,M., Takahashi,K., Okuda,T., Ohnuki,T. and Komatsubara,S.
    TMC-95A, B, C, and D, novel proteasome inhibitors produced by Apiospora montagnei Sacc. TC 1093. Taxonomy, production, isolation, and biological activities
    J Antibiot (Tokyo)53, 105-109. PubMed  Europe PubMed  I
  66. [YEAR:21-7-2000]Schmidtke,G., Emch,S., Groettrup,M. and Holzhutter,H.G.
    Evidence for the existence of a non-catalytic modifier site of peptide hydrolysis by the 20 S proteasome
    J Biol Chem275, 22056-22063. PubMed  Europe PubMed DOI  I
    67. 1999
  67. [YEAR:1-7-1999]Arendt,C.S. and Hochstrasser,M.
    Eukaryotic 20S proteasome catalytic subunit propeptides prevent active site inactivation by N-terminal acetylation and promote particle assembly
    EMBO J18, 3575-3585. PubMed  Europe PubMed DOI
  68. [YEAR:1-8-1999]Covi,J.A., Belote,J.M. and Mykles,D.L.
    Subunit compositions and catalytic properties of proteasomes from developmental temperature-sensitive mutants of Drosophila melanogaster
    Arch Biochem Biophys368, 85-97. PubMed  Europe PubMed DOI
  69. Elofsson,M., Splittgerber,U., Myung,J., Mohan,R. and Crews,C.M.
    Towards subunit-specific proteasome inhibitors: synthesis and evaluation of peptide alpha',beta'-epoxyketones
    Chem Biol6, 811-822. PubMed  Europe PubMed DOI  I
  70. [YEAR:27-8-1999]Jager,S., Groll,M., Huber,R., Wolf,D.H. and Heinemeyer,W.
    Proteasome beta-type subunits: Unequal roles of propeptides in core particle maturation and a hierarchy of active site function
    J Mol Biol291, 997-1013. PubMed  Europe PubMed DOI
  71. [YEAR:1-9-1999]Murray,B.W., Sultmann,H. and Klein,J.
    Analysis of a 26-kb region linked to the Mhc in zebrafish: Genomic organization of the proteasome component beta/transporter associated with antigen processing-2 gene cluster and identification of five new proteasome beta subunit genes
    J Immunol163, 2657-2666. PubMed  Europe PubMed
    72. 1998
  72. [YEAR:2-10-1998]Dick,T.P., Nussbaum,A.K., Deeg,M., Heinemeyer,W., Groll,M., Schirle,M., Keilholz,W., Stevanovic,S., Wolf,D.H., Huber,R., Rammensee,H.G. and Schild,H.
    Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutants
    J Biol Chem273, 25637-25646. PubMed  Europe PubMed DOI
  73. [YEAR:13-10-1998]Nussbaum,A.K., Dick,T.P., Keilholz,W., Schirle,M., Stevanovic,S., Dietz,K., Heinemeyer,W., Groll,M., Wolf,D.H., Huber,R., Rammensee,H.G. and Schild,H.
    Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1
    Proc Natl Acad Sci U S A95, 12504-12509. PubMed  Europe PubMed
  74. Yamada,S., Sato,K., Yamada,J., Yasutomi,M., Tokumoto,T. and Ishikawa,K.
    Activation of the 20S proteasome of Xenopus oocytes by SDS: evidence for the substrate-induced conformational change characteristic of trypsin-like peptidase
    Zoolog Sci15, 353-357. PubMed  Europe PubMed DOI
    75. 1997
  75. Arendt,C.S. and Hochstrasser,M.
    Identification of the yeast 20S proteasome catalytic centers and subunit interactions required for active-site formation
    Proc Natl Acad Sci U S A94, 7156-7161. PubMed  Europe PubMed DOI
  76. Eleuteri,A.M., Kohanski,R.A., Cardozo,C. and Orlowski,M.
    Bovine spleen multicatalytic proteinase complex (proteasome). Replacement of X, Y, and Z subunits by LMP7, LMP2, and MECL1 and changes in properties and specificity
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  77. [YEAR:3-4-1997]Groll,M., Ditzel,L., Lowe,J., Stock,D., Bochtler,M., Bartunik,H.D. and Huber,R.
    Structure of 20S proteasome from yeast at 2.4 A resolution
    Nature386, 463-471. PubMed  Europe PubMed DOI  S
  78. Hayashi,M., Ishibashi,T., Tanaka,K. and Kasahara,M.
    The mouse genes encoding the third pair of beta-type proteasome subunits regulated reciprocally by IFN-gamma: structural comparison, chromosomal localization, and analysis of the promoter
    J Immunol159, 2760-2770. PubMed  Europe PubMed
    79. 1996
  79. Coux,O., Tanaka,K. and Goldberg,A.L.
    Structure and functions of the 20S and 26S proteasomes
    Annu Rev Biochem65, 801-847. PubMed  Europe PubMed DOI
  80. Kasahara,M., Hayashi,M., Tanaka,K., Inoko,H., Sugaya,K., Ikemura,T. and Ishibashi,T.
    Chromosomal localization of the proteasome Z subunit gene reveals an ancient chromosomal duplication involving the major histocompatibility complex
    Proc Natl Acad Sci U S A93, 9096-9101. PubMed  Europe PubMed DOI
    81. 1994
  81. Khan,M.T., Wang,K., Auland,M.E., Kable,E.P. and Roufogalis,B.D.
    Membrane-bound high molecular mass proteinases from human erythrocytes
    Biochim Biophys Acta1209, 215-221. PubMed  Europe PubMed  I
    82. 1993
  82. Savory,P.J. and Rivett,A.J.
    Leupeptin-binding site(s) in the mammalian multicatalytic proteinase complex
    Biochem J289, 45-48. PubMed  Europe PubMed  I
    83. 1992
  83. Djaballah,H., Harness,J.A., Savory,P.J. and Rivett,A.J.
    Use of serine-protease inhibitors as probes for the different proteolytic activities of the rat liver multicatalytic proteinase complex
    Eur J Biochem209, 629-634. PubMed  Europe PubMed DOI
    84. 1991
  84. Haffter,P. and Fox,T.D.
    Nucleotide sequence of PUP1 encoding a putative proteasome subunit in Saccharomyces cerevisiae
    Nucleic Acids Res19, 5075-5075. PubMed  Europe PubMed
    85. 1989
  85. Orlowski,M. and Michaud,C.
    Pituitary multicatalytic proteinase complex. Specificity of components and aspects of proteolytic activity
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