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Literature for peptidase T01.011: proteasome subunit beta2c

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, A Assay, T Target, P Specificity, V Review, M Mutation, I Inhibitor, L Localization. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. Maurits,E., Degeling,C.G., Kisselev,A.F., Florea,B.I. and Overkleeft,H.S.
    Structure-Based Design of Fluorogenic Substrates Selective for Human Proteasome Subunits
    Chembiochem (2020) PubMed  Europe PubMed DOI
  2. Tsimokha,A.S., Artamonova,T.O., Diakonov,E.E., Khodorkovskii,M.A. and Tomilin,A.N.
    Post-Translational Modifications of Extracellular Proteasome
    Molecules (2020) 25 PubMed  Europe PubMed DOI
  3. Wysocka,M., Romanowska,A., Gruba,N., Michalska,M., Gieldon,A. and Lesner,A.
    A peptidomimetic fluorescent probe to detect the trypsin beta2 subunit of the human 20S proteasome
    Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI  A
    4. 2019
  4. Besse,A., Besse,L., Kraus,M., Mendez-Lopez,M., Bader,J., Xin,B.T., de Bruin,G., Maurits,E., Overkleeft,H.S. and Driessen,C.
    Proteasome Inhibition in Multiple Myeloma: Head-to-Head Comparison of Currently Available Proteasome Inhibitors
    Cell Chem Biol (2019) 26, 340-351. PubMed  Europe PubMed DOI  I
  5. Steverding,D., Florea,B.I. and Overkleeft,H.S.
    Trypanosoma brucei: beta2-selective proteasome inhibitors do not block the proteasomal trypsin-like activity but are trypanocidal
    Mol Biochem Parasitol (2019) 227, 1-4. PubMed  Europe PubMed DOI  I
  6. Xin,B.T., Huber,E.M., de Bruin,G., Heinemeyer,W., Maurits,E., Espinal,C., Du,Y., Janssens,M., Weyburne,E.S., Kisselev,A.F., Florea,B.I., Driessen,C., van der Marel,G.A., Groll,M. and Overkleeft,H.S.
    Structure-based design of inhibitors selective for human proteasome beta2c or beta2i subunits
    J Med Chem (2019) 62, 1626-1642. PubMed  Europe PubMed DOI  I
    7. 2018
  7. Artschwager,R., Ward,D.J., Gannon,S., Brouwer,A.J., van de Langemheen,H., Kowalski,H. and Liskamp,R.M.J.
    Potent and highly selective inhibitors of the proteasome trypsin-like site by incorporation of basic side chain containing amino acid derived sulfonyl fluorides
    J Med Chem (2018) 61, 5395-5411. PubMed  Europe PubMed DOI  I
  8. Pierce,M.R., Bakas,N.A., Pirrung,M.C. and Bachmann,A.S.
    Thiasyrbactins induce cell death via proteasome inhibition in multiple myeloma cells
    Anticancer Res (2018) 38, 5607-5613. PubMed  Europe PubMed DOI  I
    9. 2017
  9. Hewings,D.S., Flygare,J.A., Wertz,I.E. and Bogyo,M.
    Activity-based probes for the multicatalytic proteasome
    FEBS J (2017) 284, 1540-1554. PubMed  Europe PubMed DOI  V  L  I
  10. Misas-Villamil,J.C., van der Burgh,A.M., Grosse-Holz,F., Bach-Pages,M., Kovacs,J., Kaschani,F., Schilasky,S., Emon,A.E., Ruben,M., Kaiser,M., Overkleeft,H.S. and Van Der Hoorn,R.A.
    Subunit-selective proteasome activity profiling uncovers uncoupled proteasome subunit activities during bacterial infections
    Plant J (2017) 90, 418-430. PubMed  Europe PubMed DOI
  11. Rolfe,M.
    The holy grail: solid tumor efficacy by proteasome inhibition
    Cell Chem Biol (2017) 24, 125-126. PubMed  Europe PubMed DOI  T  I
  12. Weyburne,E.S., Wilkins,O.M., Sha,Z., Williams,D.A., Pletnev,A.A., de Bruin,G., Overkleeft,H.S., Goldberg,A.L., Cole,M.D. and Kisselev,A.F.
    Inhibition of the proteasome beta2 site sensitizes triple-negative breast cancer cells to beta5 inhibitors and suppresses Nrf1 activation
    Cell Chem Biol (2017) 24, 218-230. PubMed  Europe PubMed DOI  T  I
    13. 2016
  13. de Bruin,G., Xin,B.T., Kraus,M., van der Stelt,M., van der Marel,G.A., Kisselev,A.F., Driessen,C., Florea,B.I. and Overkleeft,H.S.
    A set of activity-based probes to visualize human (immuno)proteasome activities
    Angew Chem Int Ed Engl (2016) 55, 4199-4203. PubMed  Europe PubMed DOI  A  I
  14. Gruba,N., Wysocka,M., Brzezinska,M., Debowski,D., Rolka,K., Martin,N.I. and Lesner,A.
    Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome
    Anal Biochem (2016) 508, 38-45. PubMed  Europe PubMed DOI  A  P
  15. Rut,W. and Drag,M.
    Human 20S proteasome activity towards fluorogenic peptides of various chain lengths
    Biol Chem (2016) 397, 921-926. PubMed  Europe PubMed DOI  P
  16. Zhou,T., Cai,Y., Liang,L., Yang,L., Xu,F., Niu,Y., Wang,C., Zhang,J.L. and Xu,P.
    Discovery of a potent and highly specific beta2 proteasome inhibitor from a library of copper complexes
    Bioorg Med Chem Lett (2016) 26, 5780-5784. PubMed  Europe PubMed DOI  I
    17. 2015
  17. Huber,E.M., Heinemeyer,W. and Groll,M.
    Bortezomib-resistant mutant proteasomes: structural and biochemical evaluation with carfilzomib and ONX 0914
    Structure (2015) 23, 407-417. PubMed  Europe PubMed DOI  S  I
  18. Huber,E.M., de Bruin,G., Heinemeyer,W., Paniagua Soriano,G., Overkleeft,H.S. and Groll,M.
    Systematic analyses of substrate preferences of 20S proteasomes using peptidic epoxyketone inhibitors
    J Am Chem Soc (2015) 137, 7835-7842. PubMed  Europe PubMed DOI  P  S  I
  19. Koroleva,O.N., Pham,T.H., Bouvier,D., Dufau,L., Qin,L., Reboud-Ravaux,M., Ivanov,A.A., Zhuze,A.L., Gromova,E.S. and Bouvier-Durand,M.
    Bisbenzimidazole derivatives as potent inhibitors of the trypsin-like sites of the immunoproteasome core particle
    Biochimie (2015) 108C, 94-100. PubMed  Europe PubMed DOI  I
  20. Kraus,J., Kraus,M., Liu,N., Besse,L., Bader,J., Geurink,P.P., de Bruin,G., Kisselev,A.F., Overkleeft,H. and Driessen,C.
    The novel beta2-selective proteasome inhibitor LU-102 decreases phosphorylation of I kappa B and induces highly synergistic cytotoxicity in combination with ibrutinib in multiple myeloma cells
    Cancer Chemother Pharmacol (2015) 76, 383-396. PubMed  Europe PubMed DOI  I
  21. Kraus,M., Bader,J., Geurink,P.P., Weyburne,E.S., Mirabella,A.C., Silzle,T., Shabaneh,T.B., van der Linden,W.A., de Bruin,G., Haile,S.R., van Rooden,E., Appenzeller,C., Li,N., Kisselev,A.F., Overkleeft,H. and Driessen,C.
    The novel beta2-selective proteasome inhibitor LU-102 synergizes with bortezomib and carfilzomib to overcome proteasome inhibitor resistance of myeloma cells
    Haematologica (2015) 100, 1350-1360. PubMed  Europe PubMed DOI  I
  22. O'Brien,M.A., Moravec,R.A., Riss,T.L. and Bulleit,R.F.
    Homogeneous, bioluminescent proteasome assays
    Methods Mol Biol (2015) 1219, 95-114. PubMed  Europe PubMed DOI  A
  23. Yang,W., Li,L., Liu,R., Sun,G., Liu,C., Zhang,S., Jiang,P., Zhang,X., Ren,H., Wang,Z. and Cui,J.
    Molecular identification and characterization of Trichinella spiralis proteasome subunit beta type-7
    Parasit Vectors (2015) 8, 18-18. PubMed  Europe PubMed DOI  PMC  EPMC
  24. Zhu,Z., Zhang,L. and Shi,G.
    Proteasome as a molecular target of microcystin-LR
    Toxins (Basel) (2015) 7, 2221-2231. PubMed  Europe PubMed DOI  I
    25. 2014
  25. Loizidou,E.Z. and Zeinalipour-Yazdi,C.D.
    Computational inhibition studies of the human proteasome by argyrin-based analogues with subunit specificity
    Chem Biol Drug Des (2014) 84, 99-107. PubMed  Europe PubMed DOI  I
  26. Wilkins,O.M., Downey,S.L., Weyburne,E.S., Williams,D.A., Mirabella,A.C., Overkleeft,H.S. and Kisselev,A.F.
    Cell-line-specific high background in the Proteasome-Glo assay of proteasome trypsin-like activity
    Anal Biochem (2014) 451, 1-3. PubMed  Europe PubMed DOI  A
    27. 2013
  27. Geurink,P.P., van der Linden,W.A., Mirabella,A.C., Gallastegui,N., de Bruin,G., Blom,A.E., Voges,M.J., Mock,E.D., Florea,B.I., van der Marel,G.A., Driessen,C., van der Stelt,M., Groll,M., Overkleeft,H.S. and Kisselev,A.F.
    Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites
    J Med Chem (2013) 56, 1262-1275. PubMed  Europe PubMed DOI  I
  28. Gotze,S., Bose,A., Abele,D., Sokolova,I.M. and Saborowski,R.
    Pitfalls in invertebrate proteasome assays
    J Exp Biol (2013) 216, 1351-1354. PubMed  Europe PubMed DOI  A  I
    29. 2012
  29. de Jong,A., Schuurman,K.G., Rodenko,B., Ovaa,H. and Berkers,C.R.
    Fluorescence-based proteasome activity profiling
    Methods Mol Biol (2012) 803, 183-204. PubMed  Europe PubMed DOI  A
  30. Grawert,M.A. and Groll,M.
    Eukaryotic 20S proteasome
    [ISSN:978-0-12-407742-3] (2012) 3, 3684-3691. DOI
  31. Pereira,A.R., Kale,A.J., Fenley,A.T., Byrum,T., Debonsi,H.M., Gilson,M.K., Valeriote,F.A., Moore,B.S. and Gerwick,W.H.
    The carmaphycins: new proteasome inhibitors exhibiting an alpha,beta-epoxyketone warhead from a marine cyanobacterium
    Chembiochem (2012) 13, 810-817. PubMed  Europe PubMed DOI  I
    32. 2011
  32. Clark,L.A., Tsai,K.L., Starr,A.N., Nowend,K.L. and Murphy,K.E.
    A missense mutation in the 20S proteasome beta2 subunit of Great Danes having harlequin coat patterning
    Genomics (2011) 97, 244-248. PubMed  Europe PubMed DOI  M
  33. Collavoli,A., Comelli,L., Cervelli,T. and Galli,A.
    The over-expression of the beta2 catalytic subunit of the proteasome decreases homologous recombination and impairs DNA double-strand break repair in human cells
    J Biomed Biotechnol (2011) 2011, 757960-757960. PubMed  Europe PubMed DOI  PMC  EPMC
  34. Mirabella,A.C., Pletnev,A.A., Downey,S.L., Florea,B.I., Shabaneh,T.B., Britton,M., Verdoes,M., Filippov,D.V., Overkleeft,H.S. and Kisselev,A.F.
    Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib
    Chem Biol (2011) 18, 608-618. PubMed  Europe PubMed DOI  I
    35. 2010
  35. Geurink,P.P., Florea,B.I., van der Marel,G.A., Kessler,B.M. and Overkleeft,H.S.
    Probing the proteasome cavity in three steps: bio-orthogonal photo-reactive suicide substrates
    Chem Commun (Camb) (2010) 46, 9052-9054. PubMed  Europe PubMed DOI
  36. Liggett,A., Crawford,L.J., Walker,B., Morris,T.C. and Irvine,A.E.
    Methods for measuring proteasome activity: current limitations and future developments
    Leuk Res (2010) 34, 1403-1409. PubMed  Europe PubMed DOI  A
  37. Screen,M., Britton,M., Downey,S.L., Verdoes,M., Voges,M.J., Blom,A.E., Geurink,P.P., Risseeuw,M.D., Florea,B.I., van der Linden,W.A., Pletnev,A.A., Overkleeft,H.S. and Kisselev,A.F.
    Nature of pharmacophore influences active site specificity of proteasome inhibitors
    J Biol Chem (2010) 285, 40125-40134. PubMed  Europe PubMed DOI  I
  38. Wu,Y.X. and Fang,X.
    Apigenin, chrysin, and luteolin selectively inhibit chymotrypsin-like and trypsin-like proteasome catalytic activities in tumor cells
    Planta Med (2010) 76, 128-132. PubMed  Europe PubMed DOI  I
    39. 2009
  39. Britton,M., Lucas,M.M., Downey,S.L., Screen,M., Pletnev,A.A., Verdoes,M., Tokhunts,R.A., Amir,O., Goddard,A.L., Pelphrey,P.M., Wright,D.L., Overkleeft,H.S. and Kisselev,A.F.
    Selective inhibitor of proteasome's caspase-like sites sensitizes cells to specific inhibition of chymotrypsin-like sites
    Chem Biol (2009) 16, 1278-1289. PubMed  Europe PubMed DOI  I
  40. Moravec,R.A., O'Brien,M.A., Daily,W.J., Scurria,M.A., Bernad,L. and Riss,T.L.
    Cell-based bioluminescent assays for all three proteasome activities in a homogeneous format
    Anal Biochem (2009) 387, 294-302. PubMed  Europe PubMed DOI  A
    41. 2008
  41. Baldisserotto,A., Marastoni,M., Lazzari,I., Trapella,C., Gavioli,R. and Tomatis,R.
    C-terminal constrained phenylalanine as a pharmacophoric unit in peptide-based proteasome inhibitors
    Eur J Med Chem (2008) 43, 1403-1411. PubMed  Europe PubMed DOI  I
  42. Chouduri,A.U., Mishina,K., Shimizu,T., Yamazaki,M., Tokumoto,T. and Yamada,S.
    High affinity Zn2+ inhibitory site(s) for the trypsin-like peptidase of the 20S proteasome
    Arch Biochem Biophys (2008) 477, 113-120. PubMed  Europe PubMed DOI
  43. Uttenweiler-Joseph,S., Claverol,S., Sylvius,L., Bousquet-Dubouch,M.P., Burlet-Schiltz,O. and Monsarrat,B.
    Toward a full characterization of the human 20S proteasome subunits and their isoforms by a combination of proteomic approaches
    Methods Mol Biol (2008) 484, 111-130. PubMed  Europe PubMed DOI
    44. 2007
  44. Baldisserotto,A., Marastoni,M., Trapella,C., Gavioli,R., Ferretti,V., Pretto,L. and Tomatis,R.
    Glutamine vinyl ester proteasome inhibitors selective for trypsin-like (beta2) subunit
    Eur J Med Chem (2007) 42, 586-592. PubMed  Europe PubMed DOI  I
  45. Miller,C.P., Ban,K., Dujka,M.E., McConkey,D.J., Munsell,M., Palladino,M. and Chandra,J.
    NPI-0052, a novel proteasome inhibitor, induces caspase-8 and ROS-dependent apoptosis alone and in combination with HDAC inhibitors in leukemia cells
    Blood (2007) 110, 267-277. PubMed  Europe PubMed DOI  PMC  EPMC  I
    46. 2006
  46. [YEAR:15-6-2006]Crawford,L.J., Walker,B., Ovaa,H., Chauhan,D., Anderson,K.C., Morris,T.C. and Irvine,A.E.
    Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132
    Cancer Res (15-6-2006) 66, 6379-6386. PubMed  Europe PubMed DOI  I
  47. Groll,M., Gotz,M., Kaiser,M., Weyher,E. and Moroder,L.
    TMC-95-Based inhibitor design provides evidence for the catalytic versatility of the proteasome
    Chem Biol (2006) 13, 607-614. PubMed  Europe PubMed DOI  I
  48. [YEAR:2-2-2006]Kisselev,A.F., Callard,A. and Goldberg,A.L.
    Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate
    J Biol Chem (2-2-2006) 281, 8582-8590. PubMed  Europe PubMed DOI
  49. [YEAR:4-4-2006]Marastoni,M., Baldisserotto,A., Trapella,C., Gavioli,R. and Tomatis,R.
    P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors
    Bioorg Med Chem Lett (4-4-2006) 16, 3125-3130. PubMed  Europe PubMed DOI  I
    50. 2005
  50. [YEAR:9-6-2005]Braun,H.A., Umbreen,S., Groll,M., Kuckelkorn,U., Mlynarczuk,I., Wigand,M.E., Drung,I., Kloetzel,P.M. and Schmidt,B.
    Tripeptide mimetics inhibit the 20 S proteasome by covalent bonding to the active threonines
    J Biol Chem (9-6-2005) 280, 28394-28401. PubMed  Europe PubMed DOI  I
  51. Gaczynska,M. and Osmulski,P.A.
    Small-molecule inhibitors of proteasome activity
    Methods Mol Biol (2005) 301, 3-22. PubMed  Europe PubMed DOI  I
  52. Kisselev,A.F. and Goldberg,A.L.
    Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates
    Methods Enzymol (2005) 398, 364-378. PubMed  Europe PubMed DOI
  53. [YEAR:28-7-2005]Marastoni,M., Baldisserotto,A., Cellini,S., Gavioli,R. and Tomatis,R.
    Peptidyl vinyl ester derivatives: new class of selective inhibitors of proteasome trypsin-like activity
    J Med Chem (28-7-2005) 48, 5038-5042. PubMed  Europe PubMed DOI  I
  54. Steverding,D., Spackman,R.W., Royle,H.J. and Glenn,R.J.
    Trypanocidal activities of trileucine methyl vinyl sulfone proteasome inhibitors
    Parasitol Res (2005) 95, 73-76. PubMed  Europe PubMed DOI  I
    55. 2004
  55. [YEAR:29-11-2004]Groll,M. and Huber,R.
    Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach
    Biochim Biophys Acta (29-11-2004) 1695, 33-44. PubMed  Europe PubMed DOI  V  I
  56. [YEAR:2-4-2004]Ramos,P.C., Marques,A.J., London,M.K. and Dohmen,R.J.
    Role of C-terminal extensions of subunits beta2 and beta7 in assembly and activity of eukaryotic proteasomes
    J Biol Chem (2-4-2004) 279, 14323-14330. PubMed  Europe PubMed DOI
  57. Seemuller,E., Dolenc,I. and Lupas,A.
    Eukaryotic 20S proteasome
    [ISSN:0-12-079610-4] (2004) 2, 2068-2077.  V
    58. 2002
  58. [YEAR:1-12-2002]Cardozo,C. and Michaud,C.
    Proteasome-mediated degradation of tau proteins occurs independently of the chymotrypsin-like activity by a nonprocessive pathway
    Arch Biochem Biophys (1-12-2002) 408, 103-110. PubMed  Europe PubMed DOI
  59. Groll,M., Nazif,T., Huber,R. and Bogyo,M.
    Probing structural determinants distal to the site of hydrolysis that control substrate specificity of the 20S proteasome
    Chem Biol (2002) 9, 655-662. PubMed  Europe PubMed DOI  S  I
  60. Unno,M., Mizushima,T., Morimoto,Y., Tomisugi,Y., Tanaka,K., Yasuoka,N. and Tsukihara,T.
    The structure of the mammalian 20S proteasome at 2.75 A resolution
    Structure (2002) 10, 609-618. PubMed  Europe PubMed DOI  S
    61. 2001
  61. Kessler,B.M., Tortorella,D., Altun,M., Kisselev,A.F., Fiebiger,E., Hekking,B.G., Ploegh,H.L. and Overkleeft,H.S.
    Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits
    Chem Biol (2001) 8, 913-929. PubMed  Europe PubMed DOI  I
  62. [YEAR:13-3-2001]Nazif,T. and Bogyo,M.
    Global analysis of proteasomal substrate specificity using positional-scanning libraries of covalent inhibitors
    Proc Natl Acad Sci U S A (13-3-2001) 98, 2967-2972. PubMed  Europe PubMed DOI  PMC  EPMC  I
  63. [YEAR:6-11-2001]Oberdorf,J., Carlson,E.J. and Skach,W.R.
    Redundancy of mammalian proteasome beta subunit function during endoplasmic reticulum associated degradation
    Biochemistry (6-11-2001) 40, 13397-13405. PubMed  Europe PubMed DOI
    64. 2000
  64. [YEAR:19-5-2000]Kisselev,A.F., Songyang,Z. and Goldberg,A.L.
    Why does threonine, and not serine, function as the active site nucleophile in proteasomes?
    J Biol Chem (19-5-2000) 275, 14831-14837. PubMed  Europe PubMed DOI  I
  65. Koguchi,Y., Kohno,J., Nishio,M., Takahashi,K., Okuda,T., Ohnuki,T. and Komatsubara,S.
    TMC-95A, B, C, and D, novel proteasome inhibitors produced by Apiospora montagnei Sacc. TC 1093. Taxonomy, production, isolation, and biological activities
    J Antibiot (Tokyo) (2000) 53, 105-109. PubMed  Europe PubMed  I
  66. [YEAR:21-7-2000]Schmidtke,G., Emch,S., Groettrup,M. and Holzhutter,H.G.
    Evidence for the existence of a non-catalytic modifier site of peptide hydrolysis by the 20 S proteasome
    J Biol Chem (21-7-2000) 275, 22056-22063. PubMed  Europe PubMed DOI  I
    67. 1999
  67. [YEAR:1-7-1999]Arendt,C.S. and Hochstrasser,M.
    Eukaryotic 20S proteasome catalytic subunit propeptides prevent active site inactivation by N-terminal acetylation and promote particle assembly
    EMBO J (1-7-1999) 18, 3575-3585. PubMed  Europe PubMed DOI  PMC  EPMC
  68. [YEAR:1-8-1999]Covi,J.A., Belote,J.M. and Mykles,D.L.
    Subunit compositions and catalytic properties of proteasomes from developmental temperature-sensitive mutants of Drosophila melanogaster
    Arch Biochem Biophys (1-8-1999) 368, 85-97. PubMed  Europe PubMed DOI
  69. Elofsson,M., Splittgerber,U., Myung,J., Mohan,R. and Crews,C.M.
    Towards subunit-specific proteasome inhibitors: synthesis and evaluation of peptide alpha',beta'-epoxyketones
    Chem Biol (1999) 6, 811-822. PubMed  Europe PubMed DOI  I
  70. [YEAR:27-8-1999]Jager,S., Groll,M., Huber,R., Wolf,D.H. and Heinemeyer,W.
    Proteasome beta-type subunits: Unequal roles of propeptides in core particle maturation and a hierarchy of active site function
    J Mol Biol (27-8-1999) 291, 997-1013. PubMed  Europe PubMed DOI
  71. [YEAR:1-9-1999]Murray,B.W., Sultmann,H. and Klein,J.
    Analysis of a 26-kb region linked to the Mhc in zebrafish: Genomic organization of the proteasome component beta/transporter associated with antigen processing-2 gene cluster and identification of five new proteasome beta subunit genes
    J Immunol (1-9-1999) 163, 2657-2666. PubMed  Europe PubMed
    72. 1998
  72. [YEAR:2-10-1998]Dick,T.P., Nussbaum,A.K., Deeg,M., Heinemeyer,W., Groll,M., Schirle,M., Keilholz,W., Stevanovic,S., Wolf,D.H., Huber,R., Rammensee,H.G. and Schild,H.
    Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutants
    J Biol Chem (2-10-1998) 273, 25637-25646. PubMed  Europe PubMed DOI
  73. [YEAR:13-10-1998]Nussbaum,A.K., Dick,T.P., Keilholz,W., Schirle,M., Stevanovic,S., Dietz,K., Heinemeyer,W., Groll,M., Wolf,D.H., Huber,R., Rammensee,H.G. and Schild,H.
    Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1
    Proc Natl Acad Sci U S A (13-10-1998) 95, 12504-12509. PubMed  Europe PubMed  PMC  EPMC
  74. Yamada,S., Sato,K., Yamada,J., Yasutomi,M., Tokumoto,T. and Ishikawa,K.
    Activation of the 20S proteasome of Xenopus oocytes by SDS: evidence for the substrate-induced conformational change characteristic of trypsin-like peptidase
    Zoolog Sci (1998) 15, 353-357. PubMed  Europe PubMed DOI
    75. 1997
  75. Arendt,C.S. and Hochstrasser,M.
    Identification of the yeast 20S proteasome catalytic centers and subunit interactions required for active-site formation
    Proc Natl Acad Sci U S A (1997) 94, 7156-7161. PubMed  Europe PubMed DOI  PMC  EPMC
  76. Eleuteri,A.M., Kohanski,R.A., Cardozo,C. and Orlowski,M.
    Bovine spleen multicatalytic proteinase complex (proteasome). Replacement of X, Y, and Z subunits by LMP7, LMP2, and MECL1 and changes in properties and specificity
    J Biol Chem (1997) 272, 11824-11831. PubMed  Europe PubMed DOI
  77. [YEAR:3-4-1997]Groll,M., Ditzel,L., Lowe,J., Stock,D., Bochtler,M., Bartunik,H.D. and Huber,R.
    Structure of 20S proteasome from yeast at 2.4 A resolution
    Nature (3-4-1997) 386, 463-471. PubMed  Europe PubMed DOI  S
  78. Hayashi,M., Ishibashi,T., Tanaka,K. and Kasahara,M.
    The mouse genes encoding the third pair of beta-type proteasome subunits regulated reciprocally by IFN-gamma: structural comparison, chromosomal localization, and analysis of the promoter
    J Immunol (1997) 159, 2760-2770. PubMed  Europe PubMed
    79. 1996
  79. Coux,O., Tanaka,K. and Goldberg,A.L.
    Structure and functions of the 20S and 26S proteasomes
    Annu Rev Biochem (1996) 65, 801-847. PubMed  Europe PubMed DOI
  80. Kasahara,M., Hayashi,M., Tanaka,K., Inoko,H., Sugaya,K., Ikemura,T. and Ishibashi,T.
    Chromosomal localization of the proteasome Z subunit gene reveals an ancient chromosomal duplication involving the major histocompatibility complex
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