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Literature for peptidase S60.001: lactoferrin

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

(Topics flags: S Structure, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Rosa,L., Ianiro,G. and Cutone,A.
    Special Issue "New Insights into Lactoferrin"
    Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2024
  2. Ongena,R., Dierick,M., Vanrompay,D., Cox,E. and Devriendt,B.
    Lactoferrin impairs pathogen virulence through its proteolytic activity
    Front Vet Sci (2024) 11, 1428156-1428156. PubMed  Europe PubMed DOI  PMC  EPMC  V
  3. Tanaka,M., Date,M. and Mizuno,K.
    New latex agglutination assay for the determination of lactoferrin in human milk
    Int Breastfeed J (2024) 19, 74-74. PubMed  Europe PubMed DOI  PMC  EPMC
    4. 2023
  4. Alhumam,M.N., Alhumam,N. and Kandeel,M.
    The Antimicrobial Bifunctional Camel Lactoferrin: In Silico and Molecular Dynamic Perspective
    Biomed Res Int (2023) 2023, 2322286-2322286. PubMed  Europe PubMed DOI  PMC  EPMC
  5. Dyrda-Terniuk,T. and Pomastowski,P.
    The Multifaceted Roles of Bovine Lactoferrin: Molecular Structure, Isolation Methods, Analytical Characteristics, and Biological Properties
    J Agric Food Chem (2023) 71, 20500-20531. PubMed  Europe PubMed DOI  PMC  EPMC
    6. 2020
  6. Campione,E., Cosio,T., Rosa,L., Lanna,C., Di Girolamo,S., Gaziano,R., Valenti,P. and Bianchi,L.
    Lactoferrin as Protective Natural Barrier of Respiratory and Intestinal Mucosa against Coronavirus Infection and Inflammation
    Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI  V
  7. Madadlou,A.
    Food proteins are a potential resource for mining cathepsin L inhibitory drugs to combat SARS-CoV-2
    Eur J Pharmacol (2020) 885, 173499-173499. PubMed  Europe PubMed DOI  PMC  EPMC
    8. 2019
  8. Soboleva,S.E., Sedykh,S.E., Alinovskaya,L.I., Buneva,V.N. and Nevinsky,G.A.
    Cow milk lactoferrin possesses several catalytic activities
    Biomolecules (2019) 9 PubMed  Europe PubMed DOI
    9. 2016
  9. Eipper,S., Steiner,R., Lesner,A., Sienczyk,M., Palesch,D., Halatsch,M.E., Zaczynska,E., Heim,C., Hartmann,M.D., Zimecki,M., Wirtz,C.R. and Burster,T.
    Lactoferrin is an allosteric enhancer of the proteolytic activity of cathepsin G
    PLoS ONE (2016) 11, e0151509-e0151509. PubMed  Europe PubMed DOI  PMC  EPMC
  10. Giese,M., Turiello,N., Molenda,N., Palesch,D., Meid,A., Schroeder,R., Basilico,P., Benarafa,C., Halatsch,M.E., Zimecki,M., Westhoff,M.A., Wirtz,C.R. and Burster,T.
    Exogenous cathepsin G upregulates cell surface MHC class I molecules on immune and glioblastoma cells
    Oncotarget (2016) 7, 74602-74611. PubMed  Europe PubMed DOI
    11. 2012
  11. Plaut,A.G. and St Geme,J.W., III
    Lactoferrin
    [ISSN:978-0-12-407742-3] (2012) 3, 3635-3640. DOI
    12. 2011
  12. Piotukh,K., Geltinger,B., Heinrich,N., Gerth,F., Beyermann,M., Freund,C. and Schwarzer,D.
    Directed evolution of sortase A mutants with altered substrate selectivity profiles
    J Am Chem Soc (2011) 133, 17536-17539. PubMed  Europe PubMed DOI
    13. 2010
  13. Serruto,D., Spadafina,T., Ciucchi,L., Lewis,L.A., Ram,S., Tontini,M., Santini,L., Biolchi,A., Seib,K.L., Giuliani,M.M., Donnelly,J.J., Berti,F., Savino,S., Scarselli,M., Costantino,P., Kroll,J.S., O'Dwyer,C., Qiu,J., Plaut,A.G., Moxon,R., Rappuoli,R., Pizza,M. and Arico,B.
    Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans
    Proc Natl Acad Sci U S A (2010) 107, 3770-3775. PubMed  Europe PubMed DOI  PMC  EPMC
    14. 2009
  14. Baker,E.N. and Baker,H.M.
    A structural framework for understanding the multifunctional character of lactoferrin
    Biochimie (2009) 91, 3-10. PubMed  Europe PubMed DOI  S
    15. 2008
  15. Clarke,S.R. and Foster,S.J.
    IsdA protects Staphylococcus aureus against the bactericidal protease activity of apolactoferrin
    Infect Immun (2008) 76, 1518-1526. PubMed  Europe PubMed DOI  PMC  EPMC
  16. Jacobsen,L.C., Sorensen,O.E., Cowland,J.B., Borregaard,N. and Theilgaard-Monch,K.
    The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils
    J Leukoc Biol (2008) 83, 1155-1164. PubMed  Europe PubMed DOI
    17. 2005
  17. Thomassen,E.A., van Veen,H.A., van Berkel,P.H., Nuijens,J.H. and Abrahams,J.P.
    The protein structure of recombinant human lactoferrin produced in the milk of transgenic cows closely matches the structure of human milk-derived lactoferrin
    Transgenic Res (2005) 14, 397-405. PubMed  Europe PubMed DOI  S
    18. 2004
  18. Massucci,M.T., Giansanti,F., Di Nino,G., Turacchio,M., Giardi,M.F., Botti,D., Ippoliti,R., De Giulio,B., Siciliano,R., Donnarumma,G., Valenti,P., Bocedi,A., Polticelli,F., Ascenzi,P. and Antonini,G.
    Proteolytic activity of bovine lactoferrin
    Biometals (2004) 17, 249-255. PubMed  Europe PubMed DOI
  19. Ochoa,T.J. and Clearly,T.G.
    Lactoferrin disruption of bacterial type III secretion systems
    Biometals (2004) 17, 257-260. PubMed  Europe PubMed DOI
  20. Valenti,P., Berlutti,F., Conte,M.P., Longhi,C. and Seganti,L.
    Lactoferrin functions: current status and perspectives
    J Clin Gastroenterol (2004) 38, S127-S129. PubMed  Europe PubMed
    21. 2003
  21. Hendrixson,D.R., Qiu,J., Shewry,S.C., Fink,D.L., Petty,S., Baker,E.N., Plaut,A.G. and St Geme,J.W., III
    Human milk lactoferrin is a serine protease that cleaves Haemophilus surface proteins at arginine-rich sites
    Mol Microbiol (2003) 47, 607-617. PubMed  Europe PubMed DOI
  22. [YEAR:20-6-2003]Ohashi,A., Murata,E., Yamamoto,K., Majima,E., Sano,E., Le,Q.T. and Katunuma,N.
    New functions of lactoferrin and beta-casein in mammalian milk as cysteine protease inhibitors
    Biochem Biophys Res Commun (20-6-2003) 306, 98-103. PubMed  Europe PubMed DOI
    23. 2002
  23. Jameson,G.B., Anderson,B.F., Breyer,W.A., Day,C.L., Tweedie,J.W. and Baker,E.N.
    Structure of a domain-opened mutant (R121D) of the human lactoferrin N-lobe refined from a merohedrally twinned crystal form
    Acta Crystallogr D Biol Crystallogr (2002) 58, 955-962. PubMed  Europe PubMed DOI  S
  24. [YEAR:3-12-2002]Peterson,N.A., Arcus,V.L., Anderson,B.F., Tweedie,J.W., Jameson,G.B. and Baker,E.N.
    "Dilysine trigger" in transferrins probed by mutagenesis of lactoferrin: crystal structures of the R210G, R210E, and R210L mutants of human lactoferrin
    Biochemistry (3-12-2002) 41, 14167-14175. PubMed  Europe PubMed DOI  S
    25. 2000
  25. [YEAR:6-6-2000]Peterson,N.A., Anderson,B.F., Jameson,G.B., Tweedie,J.W. and Baker,E.N.
    Crystal structure and iron-binding properties of the R210K mutant of the N-lobe of human lactoferrin: implications for iron release from transferrins
    Biochemistry (6-6-2000) 39, 6625-6633. PubMed  Europe PubMed DOI  S
  26. [YEAR:8-12-2000]Plaut,A.G., Qiu,J. and St Geme,J.W., III
    Human lactoferrin proteolytic activity: analysis of the cleaved region in the IgA protease of Haemophilus influenzae
    Vaccine (8-12-2000) 19 Suppl 1, S148-S152. PubMed  Europe PubMed DOI
    27. 1999
  27. Sun,X.L., Baker,H.M., Shewry,S.C., Jameson,G.B. and Baker,E.N.
    Structure of recombinant human lactoferrin expressed in Aspergillus awamori
    Acta Crystallogr D Biol Crystallogr (1999) 55, 403-407. PubMed  Europe PubMed DOI  E  S
    28. 1998
  28. Baker,E.N., Anderson,B.F., Baker,H.M., MacGillivray,R.T., Moore,S.A., Peterson,N.A., Shewry,S.C. and Tweedie,J.W.
    Three-dimensional structure of lactoferrin. Implications for function, including comparisons with transferrin
    Adv Exp Med Biol (1998) 443, 1-14. PubMed  Europe PubMed  S
  29. [YEAR:1-11-1998]Jameson,G.B., Anderson,B.F., Norris,G.E., Thomas,D.H. and Baker,E.N.
    Structure of human apolactoferrin at 2.0 A resolution. Refinement and analysis of ligand-induced conformational change
    Acta Crystallogr D Biol Crystallogr (1-11-1998) 54, 1319-1335. PubMed  Europe PubMed  S
    30. 1997
  30. Elrod,K.C., Moore,W.R., Abraham,W.M. and Tanaka,R.D.
    Lactoferrin, a potent tryptase inhibitor, abolishes late-phase airway responses in allergic sheep
    Am J Respir Crit Care Med (1997) 156, 375-381. PubMed  Europe PubMed DOI
  31. [YEAR:28-11-1997]Moore,S.A., Anderson,B.F., Groom,C.R., Haridas,M. and Baker,E.N.
    Three-dimensional structure of diferric bovine lactoferrin at 2.8 A resolution
    J Mol Biol (28-11-1997) 274, 222-236. PubMed  Europe PubMed DOI  S
  32. [YEAR:14-1-1997]Nicholson,H., Anderson,B.F., Bland,T., Shewry,S.C., Tweedie,J.W. and Baker,E.N.
    Mutagenesis of the histidine ligand in human lactoferrin: iron binding properties and crystal structure of the histidine-253 - >methionine mutant
    Biochemistry (14-1-1997) 36, 341-346. PubMed  Europe PubMed DOI  S
    33. 1996
  33. Faber,H.R., Baker,C.J., Day,C.L., Tweedie,J.W. and Baker,E.N.
    Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants
    Biochemistry (1996) 35, 14473-14479. PubMed  Europe PubMed DOI  S
  34. Faber,H.R., Bland,T., Day,C.L., Norris,G.E., Tweedie,J.W. and Baker,E.N.
    Altered domain closure and iron binding in transferrins: the crystal structure of the Asp60Ser mutant of the amino-terminal half-molecule of human lactoferrin
    J Mol Biol (1996) 256, 352-363. PubMed  Europe PubMed DOI  S
    35. 1994
  35. Smith,C.A., Anderson,B.F., Baker,H.M. and Baker,E.N.
    Structure of copper- and oxalate-substituted human lactoferrin at 2.0 A resolution
    Acta Crystallogr D Biol Crystallogr (1994) 50, 302-316. PubMed  Europe PubMed DOI  S
    36. 1993
  36. Day,C.L., Anderson,B.F., Tweedie,J.W. and Baker,E.N.
    Structure of the recombinant N-terminal lobe of human lactoferrin at 2.0 A resolution
    J Mol Biol (1993) 232, 1084-1100. PubMed  Europe PubMed DOI  S
    37. 1989
  37. [YEAR:20-10-1989]Anderson,B.F., Baker,H.M., Norris,G.E., Rice,D.W. and Baker,E.N.
    Structure of human lactoferrin: crystallographic structure analysis and refinement at 2.8 A resolution
    J Mol Biol (20-10-1989) 209, 711-734. PubMed  Europe PubMed DOI  S
    38. 1987
  38. Anderson,B.F., Baker,H.M., Dodson,E.J., Norris,G.E., Rumball,S.V., Waters,J.M. and Baker,E.N.
    Structure of human lactoferrin at 3.2-A resolution
    Proc Natl Acad Sci U S A (1987) 84, 1769-1773. PubMed  Europe PubMed  PMC  EPMC  S

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