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Literature for peptidase S10.002: serine carboxypeptidase A

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

(Topics flags: A Assay, S Structure, T Target, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2021
  1. Ito,S., Hirota,T., Yanai,M., Muto,M., Watanabe,E., Taya,Y. and Ieiri,I.
    Effects of Genetic Polymorphisms of Cathepsin A on Metabolism of Tenofovir Alafenamide
    Genes (Basel) (2021) 12 PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2020
  2. Bouknight,K.D., Jurkouich,K.M., Compton,J.R., Khavrutskii,I.V., Guelta,M.A., Harvey,S.P. and Legler,P.M.
    Structural and kinetic evidence of aging after organophosphate inhibition of human cathepsin A
    Biochem Pharmacol (2020) , 113980-113980. PubMed  Europe PubMed DOI  I
  3. Filiptsova,K.
    BIOCHEMICAL PROPERTIES OF CARBOXYPEPTIDASE A OF THE UNTRANSFERRED TISSUE AND MALIGNANT NEOPLASM OF THE MAMMARY GLAND
    Georgian Med News (2020) , 12-17. PubMed  Europe PubMed
  4. Hohl,M., Mayr,M., Lang,L., Nickel,A.G., Barallobre Barreiro,J., Yin,X., Speer,T., Selejan,S.R., Goettsch,C., Erb,K., Fecher-Trost,C., Reil,J.C., Linz,B., Ruf,S., Hubschle,T., Maack,C., Bohm,M., Sadowski,T. and Linz,D.
    Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice
    J Biol Chem (2020) PubMed  Europe PubMed DOI
  5. Huang,L., Dai,L.S., Wu,B.L., Zhang,Y., Chen,J. and He,J.X.
    Identification and immunoregulatory role of cathepsin A in the red swamp crayfish, Procambarus clarkii
    Int J Biol Macromol (2020) 153, 865-872. PubMed  Europe PubMed DOI
  6. Kim,J.W., Mahiddine,F.Y. and Kim,G.A.
    Leptin Modulates the Metastasis of Canine Inflammatory Mammary Adenocarcinoma Cells Through Downregulation of Lysosomal Protective Protein Cathepsin A (CTSA)
    Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI  PMC  EPMC
  7. Park,S., Kwon,W., Park,J.K., Baek,S.M., Lee,S.W., Cho,G.J., Ha,Y.S., Lee,J.N., Kwon,T.G., Kim,M.O., Ryoo,Z.Y., Han,S.H., Han,J.E. and Choi,S.K.
    Suppression of cathepsin A inhibits growth, migration, and invasion by inhibiting the p38 MAPK signaling pathway in prostate cancer
    Arch Biochem Biophys (2020) 688, 108407-108407. PubMed  Europe PubMed DOI  K
  8. Xiong,L., Peng,M., Zhao,M. and Liang,Z.
    Truncated Expression of a Carboxypeptidase A from Bovine Improves Its Enzymatic Properties and Detoxification Efficiency of Ochratoxin A
    Toxins (Basel) (2020) 12 PubMed  Europe PubMed DOI
    9. 2019
  9. Cowling,R.T.
    Cathepsin A inhibitors to treat heart disease: much potential, many questions
    JACC Basic Transl Sci (2019) 4, 345-347. PubMed  Europe PubMed DOI  PMC  EPMC  T  I
  10. Finsterer,J., Scorza,C.A., Scorza,F.A. and Wakil,S.M.
    Update on hereditary, autosomal dominant cathepsin-A-related arteriopathy with strokes and leukoencephalopathy (CARASAL)
    Acta Neurol Belg (2019) 119, 299-303. PubMed  Europe PubMed DOI  M
  11. Hohl,M., Erb,K., Lang,L., Ruf,S., Hubschle,T., Dhein,S., Linz,W., Elliott,A.D., Sanders,P., Zamyatkin,O., Bohm,M., Schotten,U., Sadowski,T. and Linz,D.
    Cathepsin A mediates ventricular remote remodeling and atrial cardiomyopathy in rats with ventricular ischemia/reperfusion
    JACC Basic Transl Sci (2019) 4, 332-344. PubMed  Europe PubMed DOI  PMC  EPMC
  12. Toss,M.S., Miligy,I.M., Haj-Ahmad,R., Gorringe,K.L., AlKawaz,A., Mittal,K., Ellis,I.O., Green,A.R. and Rakha,E.A.
    The prognostic significance of lysosomal protective protein (cathepsin A) in breast ductal carcinoma in situ
    Histopathology (2019) 74, 1025-1035. PubMed  Europe PubMed DOI
    13. 2018
  13. Fu,Q., Yang,N., Gao,C., Tian,M., Zhou,S., Mu,X., Sun,F. and Li,C.
    Characterization, expression signatures and microbial binding analysis of cathepsin A in turbot, Scophthalmus maximus L. (SmCTSA)
    Fish Shellfish Immunol (2018) 81, 21-28. PubMed  Europe PubMed DOI
  14. Yamazaki,N., Kanazawa,K., Kimura,M., Ike,H., Shinomiya,M., Tanaka,S., Shinohara,Y., Minakawa,N., Itoh,K. and Takiguchi,Y.
    Use of modified U1 small nuclear RNA for rescue from exon 7 skipping caused by 5'-splice site mutation of human cathepsin A gene
    Gene (2018) 677, 41-48. PubMed  Europe PubMed DOI  M
    15. 2017
  15. Calhan,O.Y. and Seyrantepe,V.
    Mice with catalytically inactive cathepsin A display neurobehavioral alterations
    Behav Neurol (2017) 2017, 4261873-4261873. PubMed  Europe PubMed DOI  K
  16. Hwang,Y.T., Lakshmanan,R., Davagnanam,I., Thompson,A.G.B., Lynch,D.S., Houlden,H., Bajaj,N., Eriksson,S.H., Bamiou,D.E. and Warren,J.D.
    Brainstem phenotype of cathepsin A-related arteriopathy with strokes and leukoencephalopathy
    Neurol Genet (2017) 3, e165-e165. PubMed  Europe PubMed DOI  PMC  EPMC  M
  17. Kim,J.W., Kong,H.J., Nam,B.H., Park,J.Y., Kim,D.H., Jeong,J.M. and Park,C.I.
    The first report of cathepsin A gene in a teleost (rock bream, Oplegnathus fasciatus): an investigation of immune functions upon infection with several pathogens
    Dev Comp Immunol (2017) 76, 262-267. PubMed  Europe PubMed DOI
  18. Pan,X., Wang,Y., Lubke,T., Hinek,A. and Pshezhetsky,A.V.
    Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings
    PLoS ONE (2017) 12, e0172854-e0172854. PubMed  Europe PubMed DOI  PMC  EPMC  K
  19. Zhang,Q., Han,P., Huang,B., Wang,Z., Qiao,G., Wang,P. and Qi,Z.
    Molecular cloning, characterization, and expression analysis of cathepsin A in the Chinese giant salamander Andrias davidianus
    J Aquat Anim Health (2017) 29, 199-207. PubMed  Europe PubMed DOI
    20. 2016
  20. Bugiani,M., Kevelam,S.H., Bakels,H.S., Waisfisz,Q., Ceuterick-de Groote,C., Niessen,H.W., Abbink,T.E., Lesnik Oberstein,S.A. and van der Knaap,M.S.
    Cathepsin A-related arteriopathy with strokes and leukoencephalopathy (CARASAL)
    Neurology (2016) 87, 1777-1786. PubMed  Europe PubMed DOI  M
  21. Linz,D., Hohl,M., Dhein,S., Ruf,S., Reil,J.C., Kabiri,M., Wohlfart,P., Verheule,S., Bohm,M., Sadowski,T. and Schotten,U.
    Cathepsin A mediates susceptibility to atrial tachyarrhythmia and impairment of atrial emptying function in Zucker diabetic fatty rats
    Cardiovasc Res (2016) 110, 371-380. PubMed  Europe PubMed DOI  I
  22. Petrera,A., Gassenhuber,J., Ruf,S., Gunasekaran,D., Esser,J., Shahinian,J.H., Hubschle,T., Rutten,H., Sadowski,T. and Schilling,O.
    Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels
    J Transl Med (2016) 14, 153-153. PubMed  Europe PubMed DOI  PMC  EPMC  I
  23. Petrera,A., Kern,U., Linz,D., Gomez-Auli,A., Hohl,M., Gassenhuber,J., Sadowski,T. and Schilling,O.
    Proteomic profiling of cardiomyocyte-specific cathepsin A overexpression links cathepsin A to the oxidative stress response
    J Proteome Res (2016) 15, 3188-3195. PubMed  Europe PubMed DOI
  24. Tillner,J., Lehmann,A., Paehler,T., Lukacs,Z., Ruf,S., Sadowski,T., Pinquier,J.-L. and Ruetten,H.
    Tolerability, safety, and pharmacokinetics of the novel cathepsin A inhibitor SAR164653 in healthy subjects
    Clin Pharmacol Drug Dev (2016) 5, 57-68. PubMed  Europe PubMed DOI  I
  25. Timur,Z.K., Akyildiz Demir,S. and Seyrantepe,V.
    Lysosomal cathepsin A plays a significant role in the processing of endogenous bioactive peptides
    Front Mol Biosci (2016) 3, 68-68. PubMed  Europe PubMed DOI  PMC  EPMC
    26. 2015
  26. Birkus,G., Bam,R.A., Willkom,M., Frey,C.R., Tsai,L., Stray,K.M., Yant,S.R. and Cihlar,T.
    Intracellular activation of tenofovir alafenamide and the effect of viral and host protease inhibitors
    Antimicrob Agents Chemother (2015) 60, 316-322. PubMed  Europe PubMed DOI
    27. 2014
  27. Bam,R.A., Birkus,G., Babusis,D., Cihlar,T. and Yant,S.R.
    Metabolism and antiretroviral activity of tenofovir alafenamide in CD4+ T-cells and macrophages from demographically diverse donors
    Antivir Ther (2014) 19, 669-677. PubMed  Europe PubMed DOI
  28. Kolli,N. and Garman,S.C.
    Proteolytic activation of human cathepsin A
    J Biol Chem (2014) 289, 11592-11600. PubMed  Europe PubMed DOI  S
  29. Kostadinov,S., Shah,B.A., Alroy,J. and Phornphutkul,C.
    A case of galactosialidosis with novel mutations of the protective protein/cathepsin A gene: diagnosis prompted by trophoblast vacuolization on placental examination
    Pediatr Dev Pathol (2014) 17, 474-477. PubMed  Europe PubMed DOI  M
  30. Pan,X., Grigoryeva,L., Seyrantepe,V., Peng,J., Kollmann,K., Tremblay,J., Lavoie,J.L., Hinek,A., Lubke,T. and Pshezhetsky,A.V.
    Serine carboxypeptidase SCPEP1 and cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1
    PLoS Genet (2014) 10, e1004146-e1004146. PubMed  Europe PubMed DOI  PMC  EPMC
  31. Schreuder,H.A., Liesum,A., Kroll,K., Bohnisch,B., Buning,C., Ruf,S. and Sadowski,T.
    Crystal structure of cathepsin A, a novel target for the treatment of cardiovascular diseases
    Biochem Biophys Res Commun (2014) 445, 451-456. PubMed  Europe PubMed DOI  S  T  I
    32. 2013
  32. Wang,J., Fang,D.A., Wang,Y., Wang,Y.L., Cheng,L., He,L. and Wang,Q.
    Cathepsin A protein from the accessory sex gland of the Chinese mitten crab (Eriocheir sinensis) plays a key role in spermatophore digestion
    J Insect Physiol (2013) 59, 953-960. PubMed  Europe PubMed DOI
    33. 2012
  33. Pshezhetsky,A.V.
    Lysosomal carboxypeptidase A
    [ISSN:978-0-12-407742-3] (2012) 3, 3413-3418. DOI
  34. Ruf,S., Buning,C., Schreuder,H., Horstick,G., Linz,W., Olpp,T., Pernerstorfer,J., Hiss,K., Kroll,K., Kannt,A., Kohlmann,M., Linz,D., Hubschle,T., Rutten,H., Wirth,K., Schmidt,T. and Sadowski,T.
    Novel beta-amino acid derivatives as inhibitors of cathepsin A
    J Med Chem (2012) 55, 7636-7649. PubMed  Europe PubMed DOI  T  I
    35. 2011
  35. Birkus,G., Kutty,N., Frey,C.R., Shribata,R., Chou,T., Wagner,C., McDermott,M. and Cihlar,T.
    Role of cathepsin A and lysosomes in the intracellular activation of novel antipapillomavirus agent GS-9191
    Antimicrob Agents Chemother (2011) 55, 2166-2173. PubMed  Europe PubMed DOI
  36. Li,W.W., He,L., Jin,X.K., Jiang,H., Chen,L.L., Wang,Y. and Wang,Q.
    Molecular cloning, characterization and expression analysis of cathepsin A gene in Chinese mitten crab, Eriocheir sinensis
    Peptides (2011) 32, 518-525. PubMed  Europe PubMed DOI
    37. 2010
  37. Reich,M., Spindler,K.D., Burret,M., Kalbacher,H., Boehm,B.O. and Burster,T.
    Cathepsin A is expressed in primary human antigen-presenting cells
    Immunol Lett (2010) 128, 143-147. PubMed  Europe PubMed DOI
    38. 2009
  38. Wang,D., Zaitsev,S., Taylor,G., D'Azzo,A. and Bonten,E.
    Protective protein/cathepsin A rescues N-glycosylation defects in neuraminidase-1
    Biochim Biophys Acta (2009) 1790, 275-282. PubMed  Europe PubMed DOI
  39. Yoshida,T., Kadota,Y., Hitaoka,S., Kori,E., Horikawa,Y., Taguchi,M., Tsuji,D., Hirokawa,T., Chuman,H. and Itoh,K.
    Expression and molecular dynamics studies on effect of amino acid substitutions at Arg344 in human cathepsin A on the protein local conformation
    Biochim Biophys Acta (2009) 1794, 1693-1699. PubMed  Europe PubMed DOI  M
    40. 2008
  40. Seyrantepe,V., Hinek,A., Peng,J., Fedjaev,M., Ernest,S., Kadota,Y., Canuel,M., Itoh,K., Morales,C.R., Lavoie,J., Tremblay,J. and Pshezhetsky,A.V.
    Enzymatic activity of lysosomal carboxypeptidase (cathepsin) A is required for proper elastic fiber formation and inactivation of endothelin-1
    Circulation (2008) 117, 1973-1981. PubMed  Europe PubMed DOI  K  M
    41. 2007
  41. Birkus,G., Wang,R., Liu,X., Kutty,N., MacArthur,H., Cihlar,T., Gibbs,C., Swaminathan,S., Lee,W. and McDermott,M.
    Cathepsin A is the major hydrolase catalyzing the intracellular hydrolysis of the antiretroviral nucleotide phosphonoamidate prodrugs GS-7340 and GS-9131
    Antimicrob Agents Chemother (2007) 51, 543-550. PubMed  Europe PubMed DOI  PMC  EPMC
  42. Hermo,L., Korah,N., Gregory,M., Liu,L.Y., Cyr,D.G., D'Azzo,A. and Smith,C.E.
    Structural alterations of epididymal epithelial cells in cathepsin A-deficient mice affect the blood-epididymal barrier and lead to altered sperm motility
    J Androl (2007) 28, 784-797. PubMed  Europe PubMed DOI  K
  43. Motobu,M., Tsuji,N., Miyoshi,T., Huang,X., Islam,M.K., Alim,M.A. and Fujisaki,K.
    Molecular characterization of a blood-induced serine carboxypeptidase from the ixodid tick Haemaphysalis longicornis
    FEBS J (2007) 274, 3299-3312. PubMed  Europe PubMed DOI
    44. 2006
  44. [YEAR:7-6-2006]Aikawa,S., Matsuzawa,F., Satoh,Y., Kadota,Y., Doi,H. and Itoh,K.
    Prediction of the mechanism of action of omuralide (clasto-lactacystin beta-lactone) on human cathepsin A based on a structural model of the yeast proteasome beta5/PRE2-subunit/omuralide complex
    Biochim Biophys Acta (7-6-2006) 1764, 1372-1380. PubMed  Europe PubMed DOI  I
  45. Yoshida,T., Lepp,Z., Kadota,Y., Satoh,Y., Itoh,K. and Chuman,H.
    Comparative analysis of binding energy of chymostatin with human cathepsin A and its homologous proteins by molecular orbital calculation
    J Chem Inf Model (2006) 46, 2093-2103. PubMed  Europe PubMed DOI  I
    46. 2005
  46. Ostrowska,H., Kalinowska,J., Chabielska,E., Stankiewicz,A., Kruszewski,K. and Buczko,W.
    Ebelactone B, an inhibitor of extracellular cathepsin A-type enzyme, suppresses platelet aggregation ex vivo in renovascular hypertensive rats
    J Cardiovasc Pharmacol (2005) 45, 348-353. PubMed  Europe PubMed DOI  T  I
    47. 2004
  47. Itoh,K., Satoh,Y., Kadota,Y., Oheda,Y., Kuwahara,J., Shimmoto,M. and Sakuraba,H.
    Expression of lysosomal protective protein/cathepsin A in a stably transformed human neuroblastoma cell line during bi-directional differentiation into neuronal and Schwannian cells
    Neurochem Int (2004) 44, 447-457. PubMed  Europe PubMed DOI  E
  48. Pshezhetsky,A.V.
    Lysosomal carboxypeptidase A
    [ISSN:0-12-079610-4] (2004) 2, 1923-1929.  V
  49. Satoh,Y., Kadota,Y., Oheda,Y., Kuwahara,J., Aikawa,S., Matsuzawa,F., Doi,H., Aoyagi,T., Sakuraba,H. and Itoh,K.
    Microbial serine carboxypeptidase inhibitors - comparative analysis of actions on homologous enzymes derived from man, yeast and wheat
    J Antibiot (Tokyo) (2004) 57, 316-325. PubMed  Europe PubMed  I
    50. 2003
  50. [YEAR:2-1-2003]Cuervo,A.M., Mann,L., Bonten,E.J., D'Azzo,A. and Dice,J.F.
    Cathepsin A regulates chaperone-mediated autophagy through cleavage of the lysosomal receptor
    EMBO J (2-1-2003) 22, 47-59. PubMed  Europe PubMed DOI  PMC  EPMC
  51. Korah,N., Smith,C.E., D'Azzo,A., Mui,J. and Hermo,L.
    Characterization of cell- and region-specific abnormalities in the epididymis of cathepsin A deficient mice
    Mol Reprod Dev (2003) 66, 358-373. PubMed  Europe PubMed DOI  K
  52. Ostrowska,H., Dabrowska,M., Osada,J. and Mantur,M.
    Effects of ebelactone B on cathepsin A activity in intact platelets and on platelet activation
    Rocz Akad Med Bialymst (2003) 48, 150-153. PubMed  Europe PubMed  I
    53. 2002
  53. Jackman,H.L., Massad,M.G., Sekosan,M., Tan,F., Brovkovych,V., Marcic,B.M. and Erdos,E.G.
    Angiotensin 1-9 and 1-7 release in human heart: role of cathepsin A
    Hypertension (2002) 39, 976-981. PubMed  Europe PubMed DOI
    54. 2001
  54. Kozlowski,L., Stoklosa,T., Omura,S., Wojcik,C., Wojtukiewicz,M.Z., Worowski,K. and Ostrowska,H.
    Lactacystin inhibits cathepsin A activity in melanoma cell lines
    Tumour Biol (2001) 22, 211-215. PubMed  Europe PubMed DOI  I
    55. 2000
  55. Hayashi,I., Majima,M., Fujita,T., Okumura,T., Kumagai,Y., Tomita,N., Morishita,R., Higaki,J. and Ogiwara,T.
    In vivo transfer of antisense oligonucleotide against urinary kininase blunts deoxycorticosterone acetate-salt hypertension in rats
    Br J Pharmacol (2000) 131, 820-826. PubMed  Europe PubMed DOI  PMC  EPMC  I
  56. Luedtke,C.C., Andonian,S., Igdoura,S. and Hermo,L.
    Cathepsin A is expressed in a cell- and region-specific manner in the testis and epididymis and is not regulated by testicular or pituitary factors
    J Histochem Cytochem (2000) 48, 1131-1146. PubMed  Europe PubMed
  57. Takiguchi,K., Itoh,K., Shimmoto,M., Ozand,P.T., Doi,H. and Sakuraba,H.
    Structural and functional study of K453E mutant protective protein/cathepsin A causing the late infantile form of galactosialidosis
    J Hum Genet (2000) 45, 200-206. PubMed  Europe PubMed DOI
    58. 1999
  58. [YEAR:14-5-1999]Chikuma,T., Ogura,Y., Kasamatsu,M., Taguchi,K., Mitsui,K., Kato,T. and Tanaka,A.
    High-performance liquid chromatographic-fluorimetric assay for cathepsin A (lysosomal protective protein) activity
    J Chromatogr B Biomed Sci Appl (14-5-1999) 728, 59-65. PubMed  Europe PubMed DOI  A
  59. Hiraiwa,M.
    Cathepsin A/protective protein: an unusual lysosomal multifunctional protein
    Cell Mol Life Sci (1999) 56, 894-907. PubMed  Europe PubMed DOI  K
    60. 1998
  60. [YEAR:9-6-1998]Itoh,K., Shimmoto,M., Utsumi,K., Mizoguchi,N., Miharu,N., Ohama,K. and Sakuraba,H.
    Protective protein/cathepsin A loss in cultured cells derived from an early-infantile form of galactosialidosis patients homozygous for the A1184-G transition (Y395C mutation)
    Biochem Biophys Res Commun (9-6-1998) 247, 12-17. PubMed  Europe PubMed DOI
  61. Matsuzaki,H., Ueno,H., Hayashi,R. and Liao,T.H.
    Bovine spleen cathepsin A: characterization and comparison with the protective protein
    J Biochem (1998) 123, 701-706. PubMed  Europe PubMed  I
  62. Richard,C., Tranchemontagne,J., Elsliger,M.A., Mitchell,G.A., Potier,M. and Pshezhetsky,A.V.
    Molecular pathology of galactosialidosis in a patient affected with two new frameshift mutations in the cathepsin A/protective protein gene
    Hum Mutat (1998) 11, 461-469. PubMed  Europe PubMed DOI
  63. [YEAR:20-1-1998]Rudenko,G., Bonten,E., Hol,W.G. and D'Azzo,A.
    The atomic model of the human protective protein/cathepsin A suggests a structural basis for galactosialidosis
    Proc Natl Acad Sci U S A (20-1-1998) 95, 621-625. PubMed  Europe PubMed DOI  PMC  EPMC  S
  64. Skidgel,R.A. and Erdos,E.G.
    Cellular carboxypeptidases
    Immunol Rev (1998) 161, 129-141. PubMed  Europe PubMed DOI
    65. 1997
  65. Ostrowska,H., Wojcik,C., Omura,S. and Worowski,K.
    Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme
    Biochem Biophys Res Commun (1997) 234, 729-732. PubMed  Europe PubMed DOI  I
  66. Rottier,R.J. and D'Azzo,A.
    Identification of the promoters for the human and murine protective protein/cathepsin A genes
    DNA Cell Biol (1997) 16, 599-610. PubMed  Europe PubMed  K
    67. 1996
  67. [YEAR:1-1-1996]Chikuma,T., Matsumoto,K., Furukawa,A., Nakayama,N., Yajima,R., Kato,T., Ishii,Y. and Tanaka,A.
    A fluorometric assay for measuring deamidase (lysosomal protective protein) using high-performance liquid chromatography
    Anal Biochem (1-1-1996) 233, 36-41. PubMed  Europe PubMed DOI  A
  68. Elsliger,M.A., Pshezhetsky,A.V., Vinogradova,M.V., Svedas,V.K. and Potier,M.
    Comparative modeling of substrate binding in the S1' subsite of serine carboxypeptidases from yeast, wheat, and human
    Biochemistry (1996) 35, 14899-14909. PubMed  Europe PubMed DOI
  69. Kleijer,W.J., Geilen,G.C., Janse,H.C., Van Diggelen,O.P., Zhou,X.Y., Galjart,N.J., Galjaard,H. and D'Azzo,A.
    Cathepsin A deficiency in galactosialidosis: Studies of patients and carriers in 16 families
    Pediatr Res (1996) 39, 1067-1071. PubMed  Europe PubMed DOI  K
  70. Zhou,X.Y., van der Spoel,A., Rottier,R., Hale,G., Willemsen,R., Berry,G.T., Strisciuglio,P., Morrone,A., Zammarchi,E., Andria,G. and D'Azzo,A.
    Molecular and biochemical analysis of protective protein/cathepsin A mutations: correlation with clinical severity in galactosialidosis
    Hum Mol Genet (1996) 5, 1977-1987. PubMed  Europe PubMed  M
    71. 1995
  71. Jackman,H.L., Tan,F., Schraufnagel,D., Dragovic,T., Dezso,B., Becker,R.P. and Erdos,E.G.
    Plasma membrane-bound and lysosomal peptidases in human alveolar macrophages
    Am J Respir Cell Mol Biol (1995) 13, 196-204. PubMed  Europe PubMed DOI  I
  72. Jones,D.A., Cummings,J., Langdon,S.P., MacLellan,A. and Smyth,J.F.
    Characterization of the deamidase enzyme responsible for the metabolism of the anticancer peptide: H-Arg-D-Trp-NmePhe-D-Trp-Leu-Met-NH2
    Biochem Pharmacol (1995) 50, 585-590. PubMed  Europe PubMed DOI
  73. Pshezhetsky,A.V., Vinogradova,M.V., Elsliger,M.A., el-Zein,F., Svedas,V.K. and Potier,M.
    Continuous spectrophotometric assay of human lysosomal cathepsin A/protective protein in normal and galactosialidosis cells
    Anal Biochem (1995) 230, 303-307. PubMed  Europe PubMed DOI  A
  74. Rudenko,G., Bonten,E., D'Azzo,A. and Hol,W.G.
    Three-dimensional structure of the human 'protective protein': structure of the precursor form suggests a complex activation mechanism
    Structure (1995) 3, 1249-1259. PubMed  Europe PubMed  S
  75. [YEAR:1-11-1995]Zhou,X.Y., Morreau,H., Rottier,R., Davis,D., Bonten,E., Gillemans,N., Wenger,D., Grosveld,F.G., Doherty,P., Suzuki,K., Grosveld,G.C. and D'Azzo,A.
    Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with overexpressing erythroid precursor cells
    Genes Dev (1-11-1995) 9, 2623-2634. PubMed  Europe PubMed  K
    76. 1994
  76. Hanna,W.L., Turbov,J.M., Jackman,H.L., Tan,F. and Froelich,C.J.
    Dominant chymotrypsin-like esterase activity in human lymphocyte granules is mediated by the serine carboxypeptidase called cathepsin A-like protective protein
    J Immunol (1994) 153, 4663-4672. PubMed  Europe PubMed
  77. Ostrowska,H.
    Pig platelet acidic carboxypeptidases
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  78. Remington,S.J. and Breddam,K.
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