Literature for peptidase S10.002: serine carboxypeptidase A

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: A Assay, S Structure, T Target, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2021
  1. Ito,S., Hirota,T., Yanai,M., Muto,M., Watanabe,E., Taya,Y. and Ieiri,I.
    Effects of Genetic Polymorphisms of Cathepsin A on Metabolism of Tenofovir Alafenamide
    Genes (Basel)12, PubMed  Europe PubMed DOI
  2. 2020
  3. Bouknight,K.D., Jurkouich,K.M., Compton,J.R., Khavrutskii,I.V., Guelta,M.A., Harvey,S.P. and Legler,P.M.
    Structural and kinetic evidence of aging after organophosphate inhibition of human cathepsin A
    Biochem Pharmacol113980-113980. PubMed  Europe PubMed DOI  I
  4. Filiptsova,K.
    BIOCHEMICAL PROPERTIES OF CARBOXYPEPTIDASE A OF THE UNTRANSFERRED TISSUE AND MALIGNANT NEOPLASM OF THE MAMMARY GLAND
    Georgian Med News12-17. PubMed  Europe PubMed
  5. Hohl,M., Mayr,M., Lang,L., Nickel,A.G., Barallobre Barreiro,J., Yin,X., Speer,T., Selejan,S.R., Goettsch,C., Erb,K., Fecher-Trost,C., Reil,J.C., Linz,B., Ruf,S., Hubschle,T., Maack,C., Bohm,M., Sadowski,T. and Linz,D.
    Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice
    J Biol Chem PubMed  Europe PubMed DOI
  6. Huang,L., Dai,L.S., Wu,B.L., Zhang,Y., Chen,J. and He,J.X.
    Identification and immunoregulatory role of cathepsin A in the red swamp crayfish, Procambarus clarkii
    Int J Biol Macromol153, 865-872. PubMed  Europe PubMed DOI
  7. Kim,J.W., Mahiddine,F.Y. and Kim,G.A.
    Leptin Modulates the Metastasis of Canine Inflammatory Mammary Adenocarcinoma Cells Through Downregulation of Lysosomal Protective Protein Cathepsin A (CTSA)
    Int J Mol Sci21, PubMed  Europe PubMed DOI
  8. Park,S., Kwon,W., Park,J.K., Baek,S.M., Lee,S.W., Cho,G.J., Ha,Y.S., Lee,J.N., Kwon,T.G., Kim,M.O., Ryoo,Z.Y., Han,S.H., Han,J.E. and Choi,S.K.
    Suppression of cathepsin A inhibits growth, migration, and invasion by inhibiting the p38 MAPK signaling pathway in prostate cancer
    Arch Biochem Biophys688, 108407-108407. PubMed  Europe PubMed DOI  K
  9. Xiong,L., Peng,M., Zhao,M. and Liang,Z.
    Truncated Expression of a Carboxypeptidase A from Bovine Improves Its Enzymatic Properties and Detoxification Efficiency of Ochratoxin A
    Toxins (Basel)12, PubMed  Europe PubMed DOI
  10. 2019
  11. Cowling,R.T.
    Cathepsin A inhibitors to treat heart disease: much potential, many questions
    JACC Basic Transl Sci4, 345-347. PubMed  Europe PubMed DOI  T  I
  12. Finsterer,J., Scorza,C.A., Scorza,F.A. and Wakil,S.M.
    Update on hereditary, autosomal dominant cathepsin-A-related arteriopathy with strokes and leukoencephalopathy (CARASAL)
    Acta Neurol Belg119, 299-303. PubMed  Europe PubMed DOI  M
  13. Hohl,M., Erb,K., Lang,L., Ruf,S., Hubschle,T., Dhein,S., Linz,W., Elliott,A.D., Sanders,P., Zamyatkin,O., Bohm,M., Schotten,U., Sadowski,T. and Linz,D.
    Cathepsin A mediates ventricular remote remodeling and atrial cardiomyopathy in rats with ventricular ischemia/reperfusion
    JACC Basic Transl Sci4, 332-344. PubMed  Europe PubMed DOI
  14. Toss,M.S., Miligy,I.M., Haj-Ahmad,R., Gorringe,K.L., AlKawaz,A., Mittal,K., Ellis,I.O., Green,A.R. and Rakha,E.A.
    The prognostic significance of lysosomal protective protein (cathepsin A) in breast ductal carcinoma in situ
    Histopathology74, 1025-1035. PubMed  Europe PubMed DOI
  15. 2018
  16. Fu,Q., Yang,N., Gao,C., Tian,M., Zhou,S., Mu,X., Sun,F. and Li,C.
    Characterization, expression signatures and microbial binding analysis of cathepsin A in turbot, Scophthalmus maximus L. (SmCTSA)
    Fish Shellfish Immunol81, 21-28. PubMed  Europe PubMed DOI
  17. Yamazaki,N., Kanazawa,K., Kimura,M., Ike,H., Shinomiya,M., Tanaka,S., Shinohara,Y., Minakawa,N., Itoh,K. and Takiguchi,Y.
    Use of modified U1 small nuclear RNA for rescue from exon 7 skipping caused by 5'-splice site mutation of human cathepsin A gene
    Gene677, 41-48. PubMed  Europe PubMed DOI  M
  18. 2017
  19. Calhan,O.Y. and Seyrantepe,V.
    Mice with catalytically inactive cathepsin A display neurobehavioral alterations
    Behav Neurol2017, 4261873-4261873. PubMed  Europe PubMed DOI  K
  20. Hwang,Y.T., Lakshmanan,R., Davagnanam,I., Thompson,A.G.B., Lynch,D.S., Houlden,H., Bajaj,N., Eriksson,S.H., Bamiou,D.E. and Warren,J.D.
    Brainstem phenotype of cathepsin A-related arteriopathy with strokes and leukoencephalopathy
    Neurol Genet3, e165-e165. PubMed  Europe PubMed DOI  M
  21. Kim,J.W., Kong,H.J., Nam,B.H., Park,J.Y., Kim,D.H., Jeong,J.M. and Park,C.I.
    The first report of cathepsin A gene in a teleost (rock bream, Oplegnathus fasciatus): an investigation of immune functions upon infection with several pathogens
    Dev Comp Immunol76, 262-267. PubMed  Europe PubMed DOI
  22. Pan,X., Wang,Y., Lubke,T., Hinek,A. and Pshezhetsky,A.V.
    Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings
    PLoS ONE12, e0172854-e0172854. PubMed  Europe PubMed DOI  K
  23. Zhang,Q., Han,P., Huang,B., Wang,Z., Qiao,G., Wang,P. and Qi,Z.
    Molecular cloning, characterization, and expression analysis of cathepsin A in the Chinese giant salamander Andrias davidianus
    J Aquat Anim Health29, 199-207. PubMed  Europe PubMed DOI
  24. 2016
  25. Bugiani,M., Kevelam,S.H., Bakels,H.S., Waisfisz,Q., Ceuterick-de Groote,C., Niessen,H.W., Abbink,T.E., Lesnik Oberstein,S.A. and van der Knaap,M.S.
    Cathepsin A-related arteriopathy with strokes and leukoencephalopathy (CARASAL)
    Neurology87, 1777-1786. PubMed  Europe PubMed DOI  M
  26. Linz,D., Hohl,M., Dhein,S., Ruf,S., Reil,J.C., Kabiri,M., Wohlfart,P., Verheule,S., Bohm,M., Sadowski,T. and Schotten,U.
    Cathepsin A mediates susceptibility to atrial tachyarrhythmia and impairment of atrial emptying function in Zucker diabetic fatty rats
    Cardiovasc Res110, 371-380. PubMed  Europe PubMed DOI  I
  27. Petrera,A., Gassenhuber,J., Ruf,S., Gunasekaran,D., Esser,J., Shahinian,J.H., Hubschle,T., Rutten,H., Sadowski,T. and Schilling,O.
    Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels
    J Transl Med14, 153-153. PubMed  Europe PubMed DOI  I
  28. Petrera,A., Kern,U., Linz,D., Gomez-Auli,A., Hohl,M., Gassenhuber,J., Sadowski,T. and Schilling,O.
    Proteomic profiling of cardiomyocyte-specific cathepsin A overexpression links cathepsin A to the oxidative stress response
    J Proteome Res15, 3188-3195. PubMed  Europe PubMed DOI
  29. Tillner,J., Lehmann,A., Paehler,T., Lukacs,Z., Ruf,S., Sadowski,T., Pinquier,J.-L. and Ruetten,H.
    Tolerability, safety, and pharmacokinetics of the novel cathepsin A inhibitor SAR164653 in healthy subjects
    Clin Pharmacol Drug Dev5, 57-68. PubMed  Europe PubMed DOI  I
  30. Timur,Z.K., Akyildiz Demir,S. and Seyrantepe,V.
    Lysosomal cathepsin A plays a significant role in the processing of endogenous bioactive peptides
    Front Mol Biosci3, 68-68. PubMed  Europe PubMed DOI
  31. 2015
  32. Birkus,G., Bam,R.A., Willkom,M., Frey,C.R., Tsai,L., Stray,K.M., Yant,S.R. and Cihlar,T.
    Intracellular activation of tenofovir alafenamide and the effect of viral and host protease inhibitors
    Antimicrob Agents Chemother60, 316-322. PubMed  Europe PubMed DOI
  33. 2014
  34. Bam,R.A., Birkus,G., Babusis,D., Cihlar,T. and Yant,S.R.
    Metabolism and antiretroviral activity of tenofovir alafenamide in CD4+ T-cells and macrophages from demographically diverse donors
    Antivir Ther19, 669-677. PubMed  Europe PubMed DOI
  35. Kolli,N. and Garman,S.C.
    Proteolytic activation of human cathepsin A
    J Biol Chem289, 11592-11600. PubMed  Europe PubMed DOI  S
  36. Kostadinov,S., Shah,B.A., Alroy,J. and Phornphutkul,C.
    A case of galactosialidosis with novel mutations of the protective protein/cathepsin A gene: diagnosis prompted by trophoblast vacuolization on placental examination
    Pediatr Dev Pathol17, 474-477. PubMed  Europe PubMed DOI  M
  37. Pan,X., Grigoryeva,L., Seyrantepe,V., Peng,J., Kollmann,K., Tremblay,J., Lavoie,J.L., Hinek,A., Lubke,T. and Pshezhetsky,A.V.
    Serine carboxypeptidase SCPEP1 and cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1
    PLoS Genet10, e1004146-e1004146. PubMed  Europe PubMed DOI
  38. Schreuder,H.A., Liesum,A., Kroll,K., Bohnisch,B., Buning,C., Ruf,S. and Sadowski,T.
    Crystal structure of cathepsin A, a novel target for the treatment of cardiovascular diseases
    Biochem Biophys Res Commun445, 451-456. PubMed  Europe PubMed DOI  S  T  I
  39. 2013
  40. Wang,J., Fang,D.A., Wang,Y., Wang,Y.L., Cheng,L., He,L. and Wang,Q.
    Cathepsin A protein from the accessory sex gland of the Chinese mitten crab (Eriocheir sinensis) plays a key role in spermatophore digestion
    J Insect Physiol59, 953-960. PubMed  Europe PubMed DOI
  41. 2012
  42. Pshezhetsky,A.V.
    Lysosomal carboxypeptidase A
    [ISSN:978-0-12-407742-3]3, 3413-3418. DOI
  43. Ruf,S., Buning,C., Schreuder,H., Horstick,G., Linz,W., Olpp,T., Pernerstorfer,J., Hiss,K., Kroll,K., Kannt,A., Kohlmann,M., Linz,D., Hubschle,T., Rutten,H., Wirth,K., Schmidt,T. and Sadowski,T.
    Novel beta-amino acid derivatives as inhibitors of cathepsin A
    J Med Chem55, 7636-7649. PubMed  Europe PubMed DOI  T  I
  44. 2011
  45. Birkus,G., Kutty,N., Frey,C.R., Shribata,R., Chou,T., Wagner,C., McDermott,M. and Cihlar,T.
    Role of cathepsin A and lysosomes in the intracellular activation of novel antipapillomavirus agent GS-9191
    Antimicrob Agents Chemother55, 2166-2173. PubMed  Europe PubMed DOI
  46. Li,W.W., He,L., Jin,X.K., Jiang,H., Chen,L.L., Wang,Y. and Wang,Q.
    Molecular cloning, characterization and expression analysis of cathepsin A gene in Chinese mitten crab, Eriocheir sinensis
    Peptides32, 518-525. PubMed  Europe PubMed DOI
  47. 2010
  48. Reich,M., Spindler,K.D., Burret,M., Kalbacher,H., Boehm,B.O. and Burster,T.
    Cathepsin A is expressed in primary human antigen-presenting cells
    Immunol Lett128, 143-147. PubMed  Europe PubMed DOI
  49. 2009
  50. Wang,D., Zaitsev,S., Taylor,G., D'Azzo,A. and Bonten,E.
    Protective protein/cathepsin A rescues N-glycosylation defects in neuraminidase-1
    Biochim Biophys Acta1790, 275-282. PubMed  Europe PubMed DOI
  51. Yoshida,T., Kadota,Y., Hitaoka,S., Kori,E., Horikawa,Y., Taguchi,M., Tsuji,D., Hirokawa,T., Chuman,H. and Itoh,K.
    Expression and molecular dynamics studies on effect of amino acid substitutions at Arg344 in human cathepsin A on the protein local conformation
    Biochim Biophys Acta1794, 1693-1699. PubMed  Europe PubMed DOI  M
  52. 2008
  53. Seyrantepe,V., Hinek,A., Peng,J., Fedjaev,M., Ernest,S., Kadota,Y., Canuel,M., Itoh,K., Morales,C.R., Lavoie,J., Tremblay,J. and Pshezhetsky,A.V.
    Enzymatic activity of lysosomal carboxypeptidase (cathepsin) A is required for proper elastic fiber formation and inactivation of endothelin-1
    Circulation117, 1973-1981. PubMed  Europe PubMed DOI  K  M
  54. 2007
  55. Birkus,G., Wang,R., Liu,X., Kutty,N., MacArthur,H., Cihlar,T., Gibbs,C., Swaminathan,S., Lee,W. and McDermott,M.
    Cathepsin A is the major hydrolase catalyzing the intracellular hydrolysis of the antiretroviral nucleotide phosphonoamidate prodrugs GS-7340 and GS-9131
    Antimicrob Agents Chemother51, 543-550. PubMed  Europe PubMed DOI
  56. Hermo,L., Korah,N., Gregory,M., Liu,L.Y., Cyr,D.G., D'Azzo,A. and Smith,C.E.
    Structural alterations of epididymal epithelial cells in cathepsin A-deficient mice affect the blood-epididymal barrier and lead to altered sperm motility
    J Androl28, 784-797. PubMed  Europe PubMed DOI  K
  57. Motobu,M., Tsuji,N., Miyoshi,T., Huang,X., Islam,M.K., Alim,M.A. and Fujisaki,K.
    Molecular characterization of a blood-induced serine carboxypeptidase from the ixodid tick Haemaphysalis longicornis
    FEBS J274, 3299-3312. PubMed  Europe PubMed DOI
  58. 2006
  59. [YEAR:7-6-2006]Aikawa,S., Matsuzawa,F., Satoh,Y., Kadota,Y., Doi,H. and Itoh,K.
    Prediction of the mechanism of action of omuralide (clasto-lactacystin beta-lactone) on human cathepsin A based on a structural model of the yeast proteasome beta5/PRE2-subunit/omuralide complex
    Biochim Biophys Acta1764, 1372-1380. PubMed  Europe PubMed DOI  I
  60. Yoshida,T., Lepp,Z., Kadota,Y., Satoh,Y., Itoh,K. and Chuman,H.
    Comparative analysis of binding energy of chymostatin with human cathepsin A and its homologous proteins by molecular orbital calculation
    J Chem Inf Model46, 2093-2103. PubMed  Europe PubMed DOI  I
  61. 2005
  62. Ostrowska,H., Kalinowska,J., Chabielska,E., Stankiewicz,A., Kruszewski,K. and Buczko,W.
    Ebelactone B, an inhibitor of extracellular cathepsin A-type enzyme, suppresses platelet aggregation ex vivo in renovascular hypertensive rats
    J Cardiovasc Pharmacol45, 348-353. PubMed  Europe PubMed DOI  T  I
  63. 2004
  64. Itoh,K., Satoh,Y., Kadota,Y., Oheda,Y., Kuwahara,J., Shimmoto,M. and Sakuraba,H.
    Expression of lysosomal protective protein/cathepsin A in a stably transformed human neuroblastoma cell line during bi-directional differentiation into neuronal and Schwannian cells
    Neurochem Int44, 447-457. PubMed  Europe PubMed DOI  E
  65. Pshezhetsky,A.V.
    Lysosomal carboxypeptidase A
    [ISSN:0-12-079610-4]2, 1923-1929.  V
  66. Satoh,Y., Kadota,Y., Oheda,Y., Kuwahara,J., Aikawa,S., Matsuzawa,F., Doi,H., Aoyagi,T., Sakuraba,H. and Itoh,K.
    Microbial serine carboxypeptidase inhibitors - comparative analysis of actions on homologous enzymes derived from man, yeast and wheat
    J Antibiot (Tokyo)57, 316-325. PubMed  Europe PubMed  I
  67. 2003
  68. [YEAR:2-1-2003]Cuervo,A.M., Mann,L., Bonten,E.J., D'Azzo,A. and Dice,J.F.
    Cathepsin A regulates chaperone-mediated autophagy through cleavage of the lysosomal receptor
    EMBO J22, 47-59. PubMed  Europe PubMed DOI
  69. Korah,N., Smith,C.E., D'Azzo,A., Mui,J. and Hermo,L.
    Characterization of cell- and region-specific abnormalities in the epididymis of cathepsin A deficient mice
    Mol Reprod Dev66, 358-373. PubMed  Europe PubMed DOI  K
  70. Ostrowska,H., Dabrowska,M., Osada,J. and Mantur,M.
    Effects of ebelactone B on cathepsin A activity in intact platelets and on platelet activation
    Rocz Akad Med Bialymst48, 150-153. PubMed  Europe PubMed  I
  71. 2002
  72. Jackman,H.L., Massad,M.G., Sekosan,M., Tan,F., Brovkovych,V., Marcic,B.M. and Erdos,E.G.
    Angiotensin 1-9 and 1-7 release in human heart: role of cathepsin A
    Hypertension39, 976-981. PubMed  Europe PubMed DOI
  73. 2001
  74. Kozlowski,L., Stoklosa,T., Omura,S., Wojcik,C., Wojtukiewicz,M.Z., Worowski,K. and Ostrowska,H.
    Lactacystin inhibits cathepsin A activity in melanoma cell lines
    Tumour Biol22, 211-215. PubMed  Europe PubMed DOI  I
  75. 2000
  76. Hayashi,I., Majima,M., Fujita,T., Okumura,T., Kumagai,Y., Tomita,N., Morishita,R., Higaki,J. and Ogiwara,T.
    In vivo transfer of antisense oligonucleotide against urinary kininase blunts deoxycorticosterone acetate-salt hypertension in rats
    Br J Pharmacol131, 820-826. PubMed  Europe PubMed DOI  I
  77. Luedtke,C.C., Andonian,S., Igdoura,S. and Hermo,L.
    Cathepsin A is expressed in a cell- and region-specific manner in the testis and epididymis and is not regulated by testicular or pituitary factors
    J Histochem Cytochem48, 1131-1146. PubMed  Europe PubMed
  78. Takiguchi,K., Itoh,K., Shimmoto,M., Ozand,P.T., Doi,H. and Sakuraba,H.
    Structural and functional study of K453E mutant protective protein/cathepsin A causing the late infantile form of galactosialidosis
    J Hum Genet45, 200-206. PubMed  Europe PubMed DOI
  79. 1999
  80. [YEAR:14-5-1999]Chikuma,T., Ogura,Y., Kasamatsu,M., Taguchi,K., Mitsui,K., Kato,T. and Tanaka,A.
    High-performance liquid chromatographic-fluorimetric assay for cathepsin A (lysosomal protective protein) activity
    J Chromatogr B Biomed Sci Appl728, 59-65. PubMed  Europe PubMed DOI  A
  81. Hiraiwa,M.
    Cathepsin A/protective protein: an unusual lysosomal multifunctional protein
    Cell Mol Life Sci56, 894-907. PubMed  Europe PubMed DOI  K
  82. 1998
  83. [YEAR:9-6-1998]Itoh,K., Shimmoto,M., Utsumi,K., Mizoguchi,N., Miharu,N., Ohama,K. and Sakuraba,H.
    Protective protein/cathepsin A loss in cultured cells derived from an early-infantile form of galactosialidosis patients homozygous for the A1184-G transition (Y395C mutation)
    Biochem Biophys Res Commun247, 12-17. PubMed  Europe PubMed DOI
  84. Matsuzaki,H., Ueno,H., Hayashi,R. and Liao,T.H.
    Bovine spleen cathepsin A: characterization and comparison with the protective protein
    J Biochem123, 701-706. PubMed  Europe PubMed  I
  85. Richard,C., Tranchemontagne,J., Elsliger,M.A., Mitchell,G.A., Potier,M. and Pshezhetsky,A.V.
    Molecular pathology of galactosialidosis in a patient affected with two new frameshift mutations in the cathepsin A/protective protein gene
    Hum Mutat11, 461-469. PubMed  Europe PubMed DOI
  86. [YEAR:20-1-1998]Rudenko,G., Bonten,E., Hol,W.G. and D'Azzo,A.
    The atomic model of the human protective protein/cathepsin A suggests a structural basis for galactosialidosis
    Proc Natl Acad Sci U S A95, 621-625. PubMed  Europe PubMed DOI  S
  87. Skidgel,R.A. and Erdos,E.G.
    Cellular carboxypeptidases
    Immunol Rev161, 129-141. PubMed  Europe PubMed DOI
  88. 1997
  89. Ostrowska,H., Wojcik,C., Omura,S. and Worowski,K.
    Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme
    Biochem Biophys Res Commun234, 729-732. PubMed  Europe PubMed DOI  I
  90. Rottier,R.J. and D'Azzo,A.
    Identification of the promoters for the human and murine protective protein/cathepsin A genes
    DNA Cell Biol16, 599-610. PubMed  Europe PubMed  K
  91. 1996
  92. [YEAR:1-1-1996]Chikuma,T., Matsumoto,K., Furukawa,A., Nakayama,N., Yajima,R., Kato,T., Ishii,Y. and Tanaka,A.
    A fluorometric assay for measuring deamidase (lysosomal protective protein) using high-performance liquid chromatography
    Anal Biochem233, 36-41. PubMed  Europe PubMed DOI  A
  93. Elsliger,M.A., Pshezhetsky,A.V., Vinogradova,M.V., Svedas,V.K. and Potier,M.
    Comparative modeling of substrate binding in the S1' subsite of serine carboxypeptidases from yeast, wheat, and human
    Biochemistry35, 14899-14909. PubMed  Europe PubMed DOI
  94. Kleijer,W.J., Geilen,G.C., Janse,H.C., Van Diggelen,O.P., Zhou,X.Y., Galjart,N.J., Galjaard,H. and D'Azzo,A.
    Cathepsin A deficiency in galactosialidosis: Studies of patients and carriers in 16 families
    Pediatr Res39, 1067-1071. PubMed  Europe PubMed DOI  K
  95. Zhou,X.Y., van der Spoel,A., Rottier,R., Hale,G., Willemsen,R., Berry,G.T., Strisciuglio,P., Morrone,A., Zammarchi,E., Andria,G. and D'Azzo,A.
    Molecular and biochemical analysis of protective protein/cathepsin A mutations: correlation with clinical severity in galactosialidosis
    Hum Mol Genet5, 1977-1987. PubMed  Europe PubMed  M
  96. 1995
  97. Jackman,H.L., Tan,F., Schraufnagel,D., Dragovic,T., Dezso,B., Becker,R.P. and Erdos,E.G.
    Plasma membrane-bound and lysosomal peptidases in human alveolar macrophages
    Am J Respir Cell Mol Biol13, 196-204. PubMed  Europe PubMed DOI  I
  98. Jones,D.A., Cummings,J., Langdon,S.P., MacLellan,A. and Smyth,J.F.
    Characterization of the deamidase enzyme responsible for the metabolism of the anticancer peptide: H-Arg-D-Trp-NmePhe-D-Trp-Leu-Met-NH2
    Biochem Pharmacol50, 585-590. PubMed  Europe PubMed DOI
  99. Pshezhetsky,A.V., Vinogradova,M.V., Elsliger,M.A., el-Zein,F., Svedas,V.K. and Potier,M.
    Continuous spectrophotometric assay of human lysosomal cathepsin A/protective protein in normal and galactosialidosis cells
    Anal Biochem230, 303-307. PubMed  Europe PubMed DOI  A
  100. Rudenko,G., Bonten,E., D'Azzo,A. and Hol,W.G.
    Three-dimensional structure of the human 'protective protein': structure of the precursor form suggests a complex activation mechanism
    Structure3, 1249-1259. PubMed  Europe PubMed  S
  101. [YEAR:1-11-1995]Zhou,X.Y., Morreau,H., Rottier,R., Davis,D., Bonten,E., Gillemans,N., Wenger,D., Grosveld,F.G., Doherty,P., Suzuki,K., Grosveld,G.C. and D'Azzo,A.
    Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with overexpressing erythroid precursor cells
    Genes Dev9, 2623-2634. PubMed  Europe PubMed  K
  102. 1994
  103. Hanna,W.L., Turbov,J.M., Jackman,H.L., Tan,F. and Froelich,C.J.
    Dominant chymotrypsin-like esterase activity in human lymphocyte granules is mediated by the serine carboxypeptidase called cathepsin A-like protective protein
    J Immunol153, 4663-4672. PubMed  Europe PubMed
  104. Ostrowska,H.
    Pig platelet acidic carboxypeptidases
    Enzyme Protein48, 291-297. PubMed  Europe PubMed
  105. Remington,S.J. and Breddam,K.
    Carboxypeptidases C and D
    Methods Enzymol244, 231-248. PubMed  Europe PubMed DOI  V
  106. 1993
  107. [YEAR:15-1-1993]Itoh,K., Takiyama,N., Kase,R., Kondoh,K., Sano,A., Oshima,A., Sakuraba,H. and Suzuki,Y.
    Purification and characterization of human lysosomal protective protein expressed in stably transformed Chinese hamster ovary cells
    J Biol Chem268, 1180-1186. PubMed  Europe PubMed
  108. Shimmoto,M., Fukuhara,Y., Itoh,K., Oshima,A., Sakuraba,H. and Suzuki,Y.
    Protective protein gene mutations in galactosialidosis
    J Clin Invest91, 2393-2398. PubMed  Europe PubMed DOI  K
  109. 1992
  110. Jackman,H.L., Morris,P.W., Deddish,P.A., Skidgel,R.A. and Erdos,E.G.
    Inactivation of endothelin I by deamidase (lysosomal protective protein)
    J Biol Chem267, 2872-2875. PubMed  Europe PubMed
  111. Morreau,H., Galjart,N.J., Willemsen,R., Gillemans,N., Zhou,X.Y. and D'Azzo,A.
    Human lysosomal protective protein. Glycosylation, intracellular transport, and association with beta-galactosidase in the endoplasmic reticulum
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