Literature for peptidase S09.019: dipeptidyl-peptidase 9

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, P Specificity, K Knockout, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025

Ahmad,S.S., Ahmed,F., Ahmad,S., Krishnan,A. and Khan,M.A. Targeting dipeptidyl peptidase-8/9 to combat inflammation-induced osteoclastogenesis in RAW264.7 macrophages and analysis of anti-osteoclastogenesis potential of chrysin Iran J Basic Med Sci (2025) 28, 516-526. PubMed Europe PubMed DOI PMC EPMC
De Loose,J., Mertens,K., Filippi,N., Corthaut,S., Benramdane,S., Sim,Y., Van Rymenant,Y., Claesen,K., Vliegen,G., Berg,M., Gomard,T., Caljon,G., Pintelon,I., Van der Veken,P. and De Meester,I. Dipeptidyl Peptidase 9 in Human Leukocytes: Novel Inhibitors Induce Caspase-1- and Gasdermin-Dependent Cell Death Eur J Immunol (2025) 55, e51526-e51526. PubMed Europe PubMed DOI
Filippi,N., Mertens,K., De Loose,J., Benramdane,S., Hermans,R., Espadinha,M., Dirkx,L., Feijens,P.B., Nozal,V., Verhulst,E., Peeters,S., Gomard,T., Corthaut,S., Augustyns,K., Caljon,G., Schols,D., De Meester,I. and Van der Veken,P. Selective and Orally Bioavailable Dipeptidyl Peptidase 9 Inhibitors with Potent Pyroptosis Induction Properties J Med Chem (2025) 68, 23163-23184. PubMed Europe PubMed DOI
Huang,J.C., Tong,X.L., Xiang,M.S.W., Boumelhem,B.B., Foulis,D.P., Zhang,M., McKenzie,C.A., McCaughan,G.W., Reinheckel,T., Zhang,H.E. and Gorrell,M.D. Dipeptidyl peptidase 9 (DPP9) depletion from hepatocytes in experimental primary liver cancer Biochim Biophys Acta Mol Basis Dis (2025) 1871, 167819-167819. PubMed Europe PubMed DOI
Nguyen,J.M.H., Zolg,S., Geiss-Friedlander,R. and Gorrell,M.D. The multifunctional regulatory post-proline protease dipeptidyl peptidase 9 and its inhibitors: new opportunities for therapeutics Cell Mol Life Sci (2025) 82, 187-187. PubMed Europe PubMed DOI PMC EPMC V
Sewald,L., Tabak,W.W.A., Fehr,L., Zolg,S., Najdzion,M., Verhoef,C.J.A., Podlesainski,D., Geiss-Friedlander,R., Lammens,A., Kaschani,F., Hellerschmied,D., Huber,R. and Kaiser,M. Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors Nat Commun (2025) 16, 3208-3208. PubMed Europe PubMed DOI PMC EPMC I

2024

Espadinha,M., De Loose,J., Corthaut,S., Thys,S., Van Rymenant,Y., Verhulst,E., Benramdane,S., Filippi,N., Augustyns,K., Van Wielendaele,P., Pintelon,I., De Meester,I. and Van der Veken,P. Active site-directed probes targeting dipeptidyl peptidases 8 and 9 Eur J Med Chem (2024) 270, 116389-116389. PubMed Europe PubMed DOI
Hess,L., Aliar,K., Grunwald,B.T., Griffin,R., Lozan,A., Knoller,M., Khokha,R., Brummer,T. and Reinheckel,T. Dipeptidyl-peptidase 9 regulates the dynamics of tumorigenesis and metastasis in breast cancer Biochim Biophys Acta Mol Basis Dis (2024) 1870, 167133-167133. PubMed Europe PubMed DOI
Tsamouri,L.P., Hsiao,J.C. and Bachovchin,D.A. The Serine Protease DPP9 and the Redox Sensor KEAP1 Form a Mutually Inhibitory Complex J Biol Chem (2024) , 108034-108034. PubMed Europe PubMed DOI
Zhao,Y.B., Wang,S.Z., Guo,W.T., Wang,L., Tang,X., Li,J.N., Xu,L. and Zhou,Q.X. Hippocampal dipeptidyl peptidase 9 bidirectionally regulates memory associated with synaptic plasticity J Adv Res (2024) S2090-1232, 00433-8-00433-8. PubMed Europe PubMed DOI K
Zhou,Y., Chen,Y., Xuan,C., Li,X., Tan,Y., Yang,M., Cao,M., Chen,C., Huang,X. and Hu,R. DPP9 regulates NQO1 and ROS to promote resistance to chemotherapy in liver cancer cells Redox Biol (2024) 75, 103292-103292. PubMed Europe PubMed DOI
Zolg,S., Donzelli,L. and Geiss-Friedlander,R. N-terminal processing by dipeptidyl peptidase 9: Cut and Go! Biochimie (2024) 226, 180-192. PubMed Europe PubMed DOI V

2023

Benramdane,S., De Loose,J., Filippi,N., Espadinha,M., Beyens,O., Rymenant,Y.V., Dirkx,L., Bozdag,M., Feijens,P.B., Augustyns,K., Caljon,G., De Winter,H., De Meester,I. and Van der Veken,P. Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin J Med Chem (2023) 66, 12717-12738. PubMed Europe PubMed DOI
Clark,K.M., Kim,J.G., Wang,Q., Gao,H., Presti,R.M. and Shan,L. Chemical inhibition of DPP9 sensitizes the CARD8 inflammasome in HIV-1-infected cells Nat Chem Biol (2023) 19, 431-439. PubMed Europe PubMed DOI
Donzelli,L., Bolgi,O. and Geiss-Friedlander,R. The amino-dipeptidyl peptidases DPP8 and DPP9: Purification and enzymatic assays Methods Enzymol (2023) 684, 289-323. PubMed Europe PubMed DOI

2022

Benramdane,S., De Loose,J., Beyens,O., Van Rymenant,Y., Vliegen,G., Augustyns,K., De Winter,H., De Meester,I. and Van der Veken,P. Vildagliptin-Derived Dipeptidyl Peptidase 9 (DPP9) Inhibitors: Identification of a DPP8/9-Specific Lead ChemMedChem (2022) 17, e202200097-e202200097. PubMed Europe PubMed DOI I
Cui,C., Tian,X., Wei,L., Wang,Y., Wang,K. and Fu,R. New insights into the role of dipeptidyl peptidase 8 and dipeptidyl peptidase 9 and their inhibitors Front Pharmacol (2022) 13, 1002871-1002871. PubMed Europe PubMed DOI PMC EPMC V
Moecking,J., Laohamonthonkul,P., Mese,K., Hagelueken,G., Steiner,A., Harapas,C.R., Sandow,J.J., Graves,J.D., Masters,S.L. and Geyer,M. Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain J Biol Chem (2022) 298, 102645-102645. PubMed Europe PubMed DOI PMC EPMC

2021

Hollingsworth,L.R., Sharif,H., Griswold,A.R., Fontana,P., Mintseris,J., Dagbay,K.B., Paulo,J.A., Gygi,S.P., Bachovchin,D.A. and Wu,H. DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation Nature (2021) PubMed Europe PubMed DOI
Sharif,H., Hollingsworth,L.R., Griswold,A.R., Hsiao,J.C., Wang,Q., Bachovchin,D.A. and Wu,H. Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment Immunity (2021) PubMed Europe PubMed DOI

2019

de Vasconcelos,N.M., Vliegen,G., Goncalves,A., De Hert,E., Martin-Perez,R., Van Opdenbosch,N., Jallapally,A., Geiss-Friedlander,R., Lambeir,A.M., Augustyns,K., Van der Veken,P., De Meester,I. and Lamkanfi,M. DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages Life Sci Alliance (2019) 2 PubMed Europe PubMed DOI PMC EPMC I
Griswold,A.R., Cifani,P., Rao,S.D., Axelrod,A.J., Miele,M.M., Hendrickson,R.C., Kentsis,A. and Bachovchin,D.A. A chemical strategy for protease substrate profiling Cell Chem Biol (2019) 26, 901-907. PubMed Europe PubMed DOI
Griswold,A.R., Ball,D.P., Bhattacharjee,A., Chui,A.J., Rao,S.D., Taabazuing,C.Y. and Bachovchin,D.A. DPP9's Enzymatic activity and not its binding to CARD8 inhibits inflammasome activation ACS Chem Biol (2019) 14, 2424-2429. PubMed Europe PubMed DOI

2018

Kim,M., von Muenchow,L., Le Meur,T., Kueng,B., Gapp,B., Weber,D., Dietrich,W., Kovarik,J., Rolink,A.G. and Ksiazek,I. DPP9 enzymatic activity in hematopoietic cells is dispensable for mouse hematopoiesis Immunol Lett (2018) 198, 60-65. PubMed Europe PubMed DOI K
Koyani,C.N., Trummer,C., Shrestha,N., Scheruebel,S., Bourgeois,B., Plastira,I., Kickmaier,S., Sourij,H., Rainer,P.P., Madl,T., Sattler,W., Pelzmann,B., Malle,E. and von Lewinski,D. Saxagliptin but not sitagliptin inhibits CaMKII and PKC via DPP9 inhibition in cardiomyocytes Front Physiol (2018) 9, 1622-1622. PubMed Europe PubMed DOI PMC EPMC I
Ross,B., Krapp,S., Augustin,M., Kierfersauer,R., Arciniega,M., Geiss-Friedlander,R. and Huber,R. Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer Proc Natl Acad Sci U S A (2018) 115, E1437-E1437. PubMed Europe PubMed DOI PMC EPMC S

2017

Gabrilovac,J., Cupic,B., Zapletal,E., Kraus,O. and Jakic-Razumovic,J. Dipeptidyl peptidase 9 (DPP9) in human skin cells Immunobiology (2017) 222, 327-342. PubMed Europe PubMed DOI I
Kim,M., Minoux,M., Piaia,A., Kueng,B., Gapp,B., Weber,D., Haller,C., Barbieri,S., Namoto,K., Lorenz,T., Wirsching,J., Bassilana,F., Dietrich,W., Rijli,F.M. and Ksiazek,I. DPP9 enzyme activity controls survival of mouse migratory tongue muscle progenitors and its absence leads to neonatal lethality due to suckling defect Dev Biol (2017) 431, 297-308. PubMed Europe PubMed DOI K
Zapletal,E., Cupic,B. and Gabrilovac,J. Expression, subcellular localisation, and possible roles of dipeptidyl peptidase 9 (DPP9) in murine macrophages Cell Biochem Funct (2017) 35, 124-137. PubMed Europe PubMed DOI

2016

Chen,Y., Gall,M.G., Zhang,H., Keane,F.M., McCaughan,G.W., Yu,D.M. and Gorrell,M.D. Dipeptidyl peptidase 9 enzymatic activity influences the expression of neonatal metabolic genes Exp Cell Res (2016) 342, 72-82. PubMed Europe PubMed DOI
Heirbaut,L., VanGoethem,S., Jansen,K., DeWinter,H., Lamoen,N., Joossens,J., Cheng,J., Chen,X., Lambeir,A.-M., DeMeester,I., Augustyns,K. and VanDer Veken,P. Probing for improved selectivity with dipeptide-derived inhibitors of dipeptidyl peptidases 8 and 9: the impact of P1-variation MedChemComm (2016) 7, 433-438. DOI I
Waumans,Y., Vliegen,G., Maes,L., Rombouts,M., Declerck,K., Van der Veken,P., Vanden Berghe,W., De Meyer,G.R., Schrijvers,D. and De Meester,I. The dipeptidyl peptidases 4, 8, and 9 in mouse monocytes and macrophages: dpp8/9 inhibition attenuates M1 macrophage activation in mice Inflammation (2016) 39, 413-424. PubMed Europe PubMed DOI
Wilson,C.H., Zhang,H.E., Gorrell,M.D. and Abbott,C.A. Dipeptidyl peptidase 9 substrates and their discovery: current progress and the application of mass spectrometry-based approaches Biol Chem (2016) 397, 837-856. PubMed Europe PubMed DOI

2015

Huan,Y., Jiang,Q., Liu,J.-L. and Shen,Z.-F. Establishment of a dipeptidyl peptidases (DPP) 8/9 expressing cell model for evaluating the selectivity of DPP4 inhibitors J Pharmacol Toxicol Methods (2015) 71, 8-12. PubMed Europe PubMed DOI I
Zhang,H., Chen,Y., Wadham,C., McCaughan,G.W., Keane,F.M. and Gorrell,M.D. Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin Biochim Biophys Acta (2015) 1853, 470-480. PubMed Europe PubMed DOI
Zhang,H., Maqsudi,S., Rainczuk,A., Duffield,N., Lawrence,J., Keane,F.M., Justa-Schuch,D., Geiss-Friedlander,R., Gorrell,M.D. and Stephens,A.N. Identification of novel dipeptidyl peptidase 9 substrates by two-dimensional differential in-gel electrophoresis FEBS J (2015) 282, 3737-3757. PubMed Europe PubMed DOI K P

2014

Justa-Schuch,D., Moller,U. and Geiss-Friedlander,R. The amino terminus extension in the long dipeptidyl peptidase 9 isoform contains a nuclear localization signal targeting the active peptidase to the nucleus Cell Mol Life Sci (2014) 71, 3611-3626. PubMed Europe PubMed DOI

2013

Gall,M.G., Chen,Y., Vieira de Ribeiro,A.J., Zhang,H., Bailey,C.G., Spielman,D.S., Yu,D.M. and Gorrell,M.D. Targeted inactivation of dipeptidyl peptidase 9 enzymatic activity causes mouse neonate lethality PLoS ONE (2013) 8, e78378-e78378. PubMed Europe PubMed DOI PMC EPMC K
Pilla,E., Kilisch,M., Lenz,C., Urlaub,H. and Geiss-Friedlander,R. The SUMO1-E67 interacting loop peptide is an allosteric inhibitor of the dipeptidyl peptidases 8 and 9 J Biol Chem (2013) 288, 32787-32796. PubMed Europe PubMed DOI I
Wilson,C.H., Indarto,D., Doucet,A., Pogson,L.D., Pitman,M.R., McNicholas,K., Menz,R.I., Overall,C.M. and Abbott,C.A. Identifying natural substrates for dipeptidyl peptidases 8 and 9 using terminal amine isotopic labeling of substrates (TAILS) reveals in vivo roles in cellular homeostasis and energy metabolism J Biol Chem (2013) 288, 13936-13949. PubMed Europe PubMed DOI P
Zhang,H., Chen,Y., Keane,F.M. and Gorrell,M.D. Advances in understanding the expression and function of dipeptidyl peptidase 8 and 9 Mol Cancer Res (2013) 11, 1487-1496. PubMed Europe PubMed DOI

2012

De Meester,I. Dipeptidyl-peptidase 9 [ISSN:978-0-12-407742-3] (2012) 3, 3384-3389. DOI
Wu,W., Liu,Y., Milo,L.J., Jr., Shu,Y., Zhao,P., Li,Y., Woznica,I., Yu,G., Sanford,D.G., Zhou,Y., Poplawski,S.E., Connolly,B.A., Sudmeier,J.L., Bachovchin,W.W. and Lai,J.H. 4-Substituted boro-proline dipeptides: synthesis, characterization, and dipeptidyl peptidase IV, 8, and 9 activities Bioorg Med Chem Lett (2012) 22, 5536-5540. PubMed Europe PubMed DOI I

2011

Chen,S.J. and Jiaang,W.T. Current advances and therapeutic potential of agents targeting dipeptidyl peptidases-IV, -II, 8/9 and fibroblast activation protein Curr Top Med Chem (2011) 11, 1447-1463. PubMed Europe PubMed DOI I
Matheeussen,V., Baerts,L., De Meyer,G., De Keulenaer,G., Van der Veken,P., Augustyns,K., Dubois,V., Scharpe,S. and De Meester,I. Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries Biol Chem (2011) 392, 189-198. PubMed Europe PubMed DOI
Tang,H.K., Chen,K.C., Liou,G.G., Cheng,S.C., Chien,C.H., Tang,H.Y., Huang,L.H., Chang,H.P., Chou,C.Y. and Chen,X. Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9 FEBS Lett (2011) 585, 3409-3414. PubMed Europe PubMed DOI
Van Goethem,S., Matheeussen,V., Joossens,J., Lambeir,A.M., Chen,X., De Meester,I., Haemers,A., Augustyns,K. and Van der Veken,P. Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal? J Med Chem (2011) 54, 5737-5746. PubMed Europe PubMed DOI I
Yao,T.W., Kim,W.S., Yu,D.M., Sharbeen,G., McCaughan,G.W., Choi,K.Y., Xia,P. and Gorrell,M.D. A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling Mol Cancer Res (2011) 9, 948-959. PubMed Europe PubMed DOI

2010

Dubois,V., Lambeir,A.M., Vandamme,S., Matheeussen,V., Guisez,Y., Scharpe,S. and De Meester,I. Dipeptidyl peptidase 9 (DPP9) from bovine testes: identification and characterization as the short form by mass spectrometry Biochim Biophys Acta (2010) 1804, 781-788. PubMed Europe PubMed DOI
Kirby,M., Yu,D.M., O'Connor,S. and Gorrell,M.D. Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition Clin Sci (Lond) (2010) 118, 31-41. PubMed Europe PubMed DOI I

2009

Ansorge,S., Bank,U., Heimburg,A., Helmuth,M., Koch,G., Tadje,J., Lendeckel,U., Wolke,C., Neubert,K., Faust,J., Fuchs,P., Reinhold,D., Thielitz,A. and Tager,M. Recent insights into the role of dipeptidyl aminopeptidase IV (DPIV) and aminopeptidase N (APN) families in immune functions Clin Chem Lab Med (2009) 47, 253-261. PubMed Europe PubMed DOI
Geiss-Friedlander,R., Parmentier,N., Moller,U., Urlaub,H., Van den Eynde,B.J. and Melchior,F. The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides J Biol Chem (2009) 284, 27211-27219. PubMed Europe PubMed DOI
Pitman,M.R., Sulda,M.L., Kuss,B. and Abbott,C.A. Dipeptidyl peptidase 8 and 9 - guilty by association? Front Biosci (2009) 14, 3619-3633. PubMed Europe PubMed V
Reinhold,D., Goihl,A., Wrenger,S., Reinhold,A., Kuhlmann,U.C., Faust,J., Neubert,K., Thielitz,A., Brocke,S., Tager,M., Ansorge,S. and Bank,U. Role of dipeptidyl peptidase IV (DP IV)-like enzymes in T lymphocyte activation: investigations in DP IV/CD26-knockout mice Clin Chem Lab Med (2009) 47, 268-274. PubMed Europe PubMed DOI I
Tang,H.K., Tang,H.Y., Hsu,S.C., Chu,Y.R., Chien,C.H., Shu,C.H. and Chen,X. Biochemical properties and expression profile of human prolyl dipeptidase DPP9 Arch Biochem Biophys (2009) 485, 120-127. PubMed Europe PubMed DOI
Wu,J.J., Tang,H.K., Yeh,T.K., Chen,C.M., Shy,H.S., Chu,Y.R., Chien,C.H., Tsai,T.Y., Huang,Y.C., Huang,Y.L., Huang,C.H., Tseng,H.Y., Jiaang,W.T., Chao,Y.S. and Chen,X. Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor Biochem Pharmacol (2009) 78, 203-210. PubMed Europe PubMed DOI I
Yazbeck,R., Howarth,G.S. and Abbott,C.A. Dipeptidyl peptidase inhibitors, an emerging drug class for inflammatory disease? Trends Pharmacol Sci (2009) 30, 600-607. PubMed Europe PubMed DOI I
Yu,D.M., Ajami,K., Gall,M.G., Park,J., Lee,C.S., Evans,K.A., McLaughlin,E.A., Pitman,M.R., Abbott,C.A., McCaughan,G.W. and Gorrell,M.D. The in vivo expression of dipeptidyl peptidases 8 and 9 J Histochem Cytochem (2009) 57, 1025-1040. PubMed Europe PubMed DOI PMC EPMC

2008

Burkey,B.F., Hoffmann,P.K., Hassiepen,U., Trappe,J., Juedes,M. and Foley,J.E. Adverse effects of dipeptidyl peptidases 8 and 9 inhibition in rodents revisited Diabetes Obes Metab (2008) 10, 1057-1061. PubMed Europe PubMed DOI
Dubois,V., Lambeir,A.M., Van der Veken,P., Augustyns,K., Creemers,J., Chen,X., Scharpe,S. and De Meester,I. Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes Front Biosci (2008) 13, 3558-3568. PubMed Europe PubMed DOI
Schade,J., Stephan,M., Schmiedl,A., Wagner,L., Niestroj,A.J., Demuth,H.U., Frerker,N., Klemann,C., Raber,K.A., Pabst,R. and von Horsten,S. Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats J Histochem Cytochem (2008) 56, 147-155. PubMed Europe PubMed DOI PMC EPMC
Van der Veken,P., De Meester,I., Dubois,V., Soroka,A., Van Goethem,S., Maes,M.B., Brandt,I., Lambeir,A.M., Chen,X., Haemers,A., Scharpe,S. and Augustyns,K. Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: Identification of dipeptide derived leads Bioorg Med Chem Lett (2008) 18, 4154-4158. PubMed Europe PubMed DOI I
Van Goethem,S., Van der Veken,P., Dubois,V., Soroka,A., Lambeir,A.M., Chen,X., Haemers,A., Scharpe,S., De Meester,I. and Augustyns,K. Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: Isoindoline containing inhibitors Bioorg Med Chem Lett (2008) 18, 4159-4162. PubMed Europe PubMed DOI I

2007

Frerker,N., Wagner,L., Wolf,R., Heiser,U., Hoffmann,T., Rahfeld,J.U., Schade,J., Karl,T., Naim,H.Y., Alfalah,M., Demuth,H.U. and von Horsten,S. Neuropeptide Y (NPY) cleaving enzymes: structural and functional homologues of dipeptidyl peptidase 4 Peptides (2007) 28, 257-268. PubMed Europe PubMed DOI
Maes,M.B., Dubois,V., Brandt,I., Lambeir,A.M., Van der Veken,P., Augustyns,K., Cheng,J.D., Chen,X., Scharpe,S. and De Meester,I. Dipeptidyl peptidase 8/9-like activity in human leukocytes J Leukoc Biol (2007) 81, 1252-1257. PubMed Europe PubMed DOI
Rummey,C. and Metz,G. Homology models of dipeptidyl peptidases 8 and 9 with a focus on loop predictions near the active site Proteins (2007) 66, 160-171. PubMed Europe PubMed DOI S
Thornberry,N.A. and Weber,A.E. Discovery of JANUVIA (Sitagliptin), a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes Curr Top Med Chem (2007) 7, 557-568. PubMed Europe PubMed DOI I
Van der Veken,P., Haemers,A. and Augustyns,K. Prolyl peptidases related to dipeptidyl peptidase IV: potential of specific inhibitors in drug discovery Curr Top Med Chem (2007) 7, 621-635. PubMed Europe PubMed DOI V

2006

Bjelke,J.R., Kanstrup,A.B. and Rasmussen,H.B. Selectivity among dipeptidyl peptidases of the S9b family Cell Mol Biol Incl Cyto Enzymol (2006) 52, 3-7. PubMed Europe PubMed DOI P
[YEAR:13-2-2006]Bjelke,J.R., Christensen,J., Nielsen,P.F., Branner,S., Kanstrup,A.B., Wagtmann,N. and Rasmussen,H.B. Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV Biochem J (13-2-2006) 396, 391-399. PubMed Europe PubMed DOI PMC EPMC P
Yu,D.M., Wang,X.M., McCaughan,G.W. and Gorrell,M.D. Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis FEBS J (2006) 273, 2447-2460. PubMed Europe PubMed DOI

2005

Lankas,G.R., Leiting,B., Roy,R.S., Eiermann,G.J., Beconi,M.G., Biftu,T., Chan,C.C., Edmondson,S., Feeney,W.P., He,H., Ippolito,D.E., Kim,D., Lyons,K.A., Ok,H.O., Patel,R.A., Petrov,A.N., Pryor,K.A., Qian,X., Reigle,L., Woods,A., Wu,J.K., Zaller,D., Zhang,X., Zhu,L., Weber,A.E. and Thornberry,N.A. Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9 Diabetes (2005) 54, 2988-2994. PubMed Europe PubMed DOI I

2004

[YEAR:13-7-2004]Ajami,K., Abbott,C.A., McCaughan,G.W. and Gorrell,M.D. Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity Biochim Biophys Acta (13-7-2004) 1679, 18-28. PubMed Europe PubMed DOI

2002

[YEAR:16-10-2002]Olsen,C. and Wagtmann,N. Identification and characterization of human DPP9, a novel homologue of dipeptidyl peptidase IV Gene (16-10-2002) 299, 185-193. PubMed Europe PubMed DOI