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Literature for peptidase S09.019: dipeptidyl-peptidase 9

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, P Specificity, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Ahmad,S.S., Ahmed,F., Ahmad,S., Krishnan,A. and Khan,M.A.
    Targeting dipeptidyl peptidase-8/9 to combat inflammation-induced osteoclastogenesis in RAW264.7 macrophages and analysis of anti-osteoclastogenesis potential of chrysin
    Iran J Basic Med Sci28, 516-526. PubMed  Europe PubMed DOI
    2. 2024
  2. Espadinha,M., De Loose,J., Corthaut,S., Thys,S., Van Rymenant,Y., Verhulst,E., Benramdane,S., Filippi,N., Augustyns,K., Van Wielendaele,P., Pintelon,I., De Meester,I. and Van der Veken,P.
    Active site-directed probes targeting dipeptidyl peptidases 8 and 9
    Eur J Med Chem270, 116389-116389. PubMed  Europe PubMed DOI
  3. Hess,L., Aliar,K., Grunwald,B.T., Griffin,R., Lozan,A., Knoller,M., Khokha,R., Brummer,T. and Reinheckel,T.
    Dipeptidyl-peptidase 9 regulates the dynamics of tumorigenesis and metastasis in breast cancer
    Biochim Biophys Acta Mol Basis Dis1870, 167133-167133. PubMed  Europe PubMed DOI
  4. Tsamouri,L.P., Hsiao,J.C. and Bachovchin,D.A.
    The Serine Protease DPP9 and the Redox Sensor KEAP1 Form a Mutually Inhibitory Complex
    J Biol Chem108034-108034. PubMed  Europe PubMed DOI
  5. Zhao,Y.B., Wang,S.Z., Guo,W.T., Wang,L., Tang,X., Li,J.N., Xu,L. and Zhou,Q.X.
    Hippocampal dipeptidyl peptidase 9 bidirectionally regulates memory associated with synaptic plasticity
    J Adv ResS2090-1232, 00433-8-00433-8. PubMed  Europe PubMed DOI  K
  6. Zhou,Y., Chen,Y., Xuan,C., Li,X., Tan,Y., Yang,M., Cao,M., Chen,C., Huang,X. and Hu,R.
    DPP9 regulates NQO1 and ROS to promote resistance to chemotherapy in liver cancer cells
    Redox Biol75, 103292-103292. PubMed  Europe PubMed DOI
  7. Zolg,S., Donzelli,L. and Geiss-Friedlander,R.
    N-terminal processing by dipeptidyl peptidase 9: Cut and Go!
    Biochimie226, 180-192. PubMed  Europe PubMed DOI  V
    8. 2023
  8. Benramdane,S., De Loose,J., Filippi,N., Espadinha,M., Beyens,O., Rymenant,Y.V., Dirkx,L., Bozdag,M., Feijens,P.B., Augustyns,K., Caljon,G., De Winter,H., De Meester,I. and Van der Veken,P.
    Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin
    J Med Chem66, 12717-12738. PubMed  Europe PubMed DOI
  9. Clark,K.M., Kim,J.G., Wang,Q., Gao,H., Presti,R.M. and Shan,L.
    Chemical inhibition of DPP9 sensitizes the CARD8 inflammasome in HIV-1-infected cells
    Nat Chem Biol19, 431-439. PubMed  Europe PubMed DOI
  10. Donzelli,L., Bolgi,O. and Geiss-Friedlander,R.
    The amino-dipeptidyl peptidases DPP8 and DPP9: Purification and enzymatic assays
    Methods Enzymol684, 289-323. PubMed  Europe PubMed DOI
    11. 2022
  11. Benramdane,S., De Loose,J., Beyens,O., Van Rymenant,Y., Vliegen,G., Augustyns,K., De Winter,H., De Meester,I. and Van der Veken,P.
    Vildagliptin-Derived Dipeptidyl Peptidase 9 (DPP9) Inhibitors: Identification of a DPP8/9-Specific Lead
    ChemMedChem17, e202200097-e202200097. PubMed  Europe PubMed DOI  I
  12. Cui,C., Tian,X., Wei,L., Wang,Y., Wang,K. and Fu,R.
    New insights into the role of dipeptidyl peptidase 8 and dipeptidyl peptidase 9 and their inhibitors
    Front Pharmacol13, 1002871-1002871. PubMed  Europe PubMed DOI  V
  13. Moecking,J., Laohamonthonkul,P., Mese,K., Hagelueken,G., Steiner,A., Harapas,C.R., Sandow,J.J., Graves,J.D., Masters,S.L. and Geyer,M.
    Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain
    J Biol Chem298, 102645-102645. PubMed  Europe PubMed DOI
    14. 2021
  14. Hollingsworth,L.R., Sharif,H., Griswold,A.R., Fontana,P., Mintseris,J., Dagbay,K.B., Paulo,J.A., Gygi,S.P., Bachovchin,D.A. and Wu,H.
    DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation
    Nature PubMed  Europe PubMed DOI
  15. Sharif,H., Hollingsworth,L.R., Griswold,A.R., Hsiao,J.C., Wang,Q., Bachovchin,D.A. and Wu,H.
    Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment
    Immunity PubMed  Europe PubMed DOI
    16. 2019
  16. de Vasconcelos,N.M., Vliegen,G., Goncalves,A., De Hert,E., Martin-Perez,R., Van Opdenbosch,N., Jallapally,A., Geiss-Friedlander,R., Lambeir,A.M., Augustyns,K., Van der Veken,P., De Meester,I. and Lamkanfi,M.
    DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages
    Life Sci Alliance2, PubMed  Europe PubMed DOI  I
  17. Griswold,A.R., Cifani,P., Rao,S.D., Axelrod,A.J., Miele,M.M., Hendrickson,R.C., Kentsis,A. and Bachovchin,D.A.
    A chemical strategy for protease substrate profiling
    Cell Chem Biol26, 901-907. PubMed  Europe PubMed DOI
  18. Griswold,A.R., Ball,D.P., Bhattacharjee,A., Chui,A.J., Rao,S.D., Taabazuing,C.Y. and Bachovchin,D.A.
    DPP9's Enzymatic activity and not its binding to CARD8 inhibits inflammasome activation
    ACS Chem Biol14, 2424-2429. PubMed  Europe PubMed DOI
    19. 2018
  19. Kim,M., von Muenchow,L., Le Meur,T., Kueng,B., Gapp,B., Weber,D., Dietrich,W., Kovarik,J., Rolink,A.G. and Ksiazek,I.
    DPP9 enzymatic activity in hematopoietic cells is dispensable for mouse hematopoiesis
    Immunol Lett198, 60-65. PubMed  Europe PubMed DOI  K
  20. Koyani,C.N., Trummer,C., Shrestha,N., Scheruebel,S., Bourgeois,B., Plastira,I., Kickmaier,S., Sourij,H., Rainer,P.P., Madl,T., Sattler,W., Pelzmann,B., Malle,E. and von Lewinski,D.
    Saxagliptin but not sitagliptin inhibits CaMKII and PKC via DPP9 inhibition in cardiomyocytes
    Front Physiol9, 1622-1622. PubMed  Europe PubMed DOI  I
  21. Ross,B., Krapp,S., Augustin,M., Kierfersauer,R., Arciniega,M., Geiss-Friedlander,R. and Huber,R.
    Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer
    Proc Natl Acad Sci U S A115, E1437-E1437. PubMed  Europe PubMed DOI  S
    22. 2017
  22. Gabrilovac,J., Cupic,B., Zapletal,E., Kraus,O. and Jakic-Razumovic,J.
    Dipeptidyl peptidase 9 (DPP9) in human skin cells
    Immunobiology222, 327-342. PubMed  Europe PubMed DOI  I
  23. Kim,M., Minoux,M., Piaia,A., Kueng,B., Gapp,B., Weber,D., Haller,C., Barbieri,S., Namoto,K., Lorenz,T., Wirsching,J., Bassilana,F., Dietrich,W., Rijli,F.M. and Ksiazek,I.
    DPP9 enzyme activity controls survival of mouse migratory tongue muscle progenitors and its absence leads to neonatal lethality due to suckling defect
    Dev Biol431, 297-308. PubMed  Europe PubMed DOI  K
  24. Zapletal,E., Cupic,B. and Gabrilovac,J.
    Expression, subcellular localisation, and possible roles of dipeptidyl peptidase 9 (DPP9) in murine macrophages
    Cell Biochem Funct35, 124-137. PubMed  Europe PubMed DOI
    25. 2016
  25. Chen,Y., Gall,M.G., Zhang,H., Keane,F.M., McCaughan,G.W., Yu,D.M. and Gorrell,M.D.
    Dipeptidyl peptidase 9 enzymatic activity influences the expression of neonatal metabolic genes
    Exp Cell Res342, 72-82. PubMed  Europe PubMed DOI
  26. Heirbaut,L., VanGoethem,S., Jansen,K., DeWinter,H., Lamoen,N., Joossens,J., Cheng,J., Chen,X., Lambeir,A.-M., DeMeester,I., Augustyns,K. and VanDer Veken,P.
    Probing for improved selectivity with dipeptide-derived inhibitors of dipeptidyl peptidases 8 and 9: the impact of P1-variation
    MedChemComm7, 433-438. DOI  I
  27. Waumans,Y., Vliegen,G., Maes,L., Rombouts,M., Declerck,K., Van der Veken,P., Vanden Berghe,W., De Meyer,G.R., Schrijvers,D. and De Meester,I.
    The dipeptidyl peptidases 4, 8, and 9 in mouse monocytes and macrophages: dpp8/9 inhibition attenuates M1 macrophage activation in mice
    Inflammation39, 413-424. PubMed  Europe PubMed DOI
  28. Wilson,C.H., Zhang,H.E., Gorrell,M.D. and Abbott,C.A.
    Dipeptidyl peptidase 9 substrates and their discovery: current progress and the application of mass spectrometry-based approaches
    Biol Chem397, 837-856. PubMed  Europe PubMed DOI
    29. 2015
  29. Huan,Y., Jiang,Q., Liu,J.-L. and Shen,Z.-F.
    Establishment of a dipeptidyl peptidases (DPP) 8/9 expressing cell model for evaluating the selectivity of DPP4 inhibitors
    J Pharmacol Toxicol Methods71, 8-12. PubMed  Europe PubMed DOI  I
  30. Zhang,H., Chen,Y., Wadham,C., McCaughan,G.W., Keane,F.M. and Gorrell,M.D.
    Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin
    Biochim Biophys Acta1853, 470-480. PubMed  Europe PubMed DOI
  31. Zhang,H., Maqsudi,S., Rainczuk,A., Duffield,N., Lawrence,J., Keane,F.M., Justa-Schuch,D., Geiss-Friedlander,R., Gorrell,M.D. and Stephens,A.N.
    Identification of novel dipeptidyl peptidase 9 substrates by two-dimensional differential in-gel electrophoresis
    FEBS J282, 3737-3757. PubMed  Europe PubMed DOI  K  P
    32. 2014
  32. Justa-Schuch,D., Moller,U. and Geiss-Friedlander,R.
    The amino terminus extension in the long dipeptidyl peptidase 9 isoform contains a nuclear localization signal targeting the active peptidase to the nucleus
    Cell Mol Life Sci71, 3611-3626. PubMed  Europe PubMed DOI
    33. 2013
  33. Gall,M.G., Chen,Y., Vieira de Ribeiro,A.J., Zhang,H., Bailey,C.G., Spielman,D.S., Yu,D.M. and Gorrell,M.D.
    Targeted inactivation of dipeptidyl peptidase 9 enzymatic activity causes mouse neonate lethality
    PLoS ONE8, e78378-e78378. PubMed  Europe PubMed DOI  K
  34. Pilla,E., Kilisch,M., Lenz,C., Urlaub,H. and Geiss-Friedlander,R.
    The SUMO1-E67 interacting loop peptide is an allosteric inhibitor of the dipeptidyl peptidases 8 and 9
    J Biol Chem288, 32787-32796. PubMed  Europe PubMed DOI  I
  35. Wilson,C.H., Indarto,D., Doucet,A., Pogson,L.D., Pitman,M.R., McNicholas,K., Menz,R.I., Overall,C.M. and Abbott,C.A.
    Identifying natural substrates for dipeptidyl peptidases 8 and 9 using terminal amine isotopic labeling of substrates (TAILS) reveals in vivo roles in cellular homeostasis and energy metabolism
    J Biol Chem288, 13936-13949. PubMed  Europe PubMed DOI  P
  36. Zhang,H., Chen,Y., Keane,F.M. and Gorrell,M.D.
    Advances in understanding the expression and function of dipeptidyl peptidase 8 and 9
    Mol Cancer Res11, 1487-1496. PubMed  Europe PubMed DOI
    37. 2012
  37. De Meester,I.
    Dipeptidyl-peptidase 9
    [ISSN:978-0-12-407742-3]3, 3384-3389. DOI
  38. Wu,W., Liu,Y., Milo,L.J., Jr., Shu,Y., Zhao,P., Li,Y., Woznica,I., Yu,G., Sanford,D.G., Zhou,Y., Poplawski,S.E., Connolly,B.A., Sudmeier,J.L., Bachovchin,W.W. and Lai,J.H.
    4-Substituted boro-proline dipeptides: synthesis, characterization, and dipeptidyl peptidase IV, 8, and 9 activities
    Bioorg Med Chem Lett22, 5536-5540. PubMed  Europe PubMed DOI  I
    39. 2011
  39. Chen,S.J. and Jiaang,W.T.
    Current advances and therapeutic potential of agents targeting dipeptidyl peptidases-IV, -II, 8/9 and fibroblast activation protein
    Curr Top Med Chem11, 1447-1463. PubMed  Europe PubMed DOI  I
  40. Matheeussen,V., Baerts,L., De Meyer,G., De Keulenaer,G., Van der Veken,P., Augustyns,K., Dubois,V., Scharpe,S. and De Meester,I.
    Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries
    Biol Chem392, 189-198. PubMed  Europe PubMed DOI
  41. Tang,H.K., Chen,K.C., Liou,G.G., Cheng,S.C., Chien,C.H., Tang,H.Y., Huang,L.H., Chang,H.P., Chou,C.Y. and Chen,X.
    Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9
    FEBS Lett585, 3409-3414. PubMed  Europe PubMed DOI
  42. Van Goethem,S., Matheeussen,V., Joossens,J., Lambeir,A.M., Chen,X., De Meester,I., Haemers,A., Augustyns,K. and Van der Veken,P.
    Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal?
    J Med Chem54, 5737-5746. PubMed  Europe PubMed DOI  I
  43. Yao,T.W., Kim,W.S., Yu,D.M., Sharbeen,G., McCaughan,G.W., Choi,K.Y., Xia,P. and Gorrell,M.D.
    A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling
    Mol Cancer Res9, 948-959. PubMed  Europe PubMed DOI
    44. 2010
  44. Dubois,V., Lambeir,A.M., Vandamme,S., Matheeussen,V., Guisez,Y., Scharpe,S. and De Meester,I.
    Dipeptidyl peptidase 9 (DPP9) from bovine testes: identification and characterization as the short form by mass spectrometry
    Biochim Biophys Acta1804, 781-788. PubMed  Europe PubMed DOI
  45. Kirby,M., Yu,D.M., O'Connor,S. and Gorrell,M.D.
    Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition
    Clin Sci (Lond)118, 31-41. PubMed  Europe PubMed DOI  I
    46. 2009
  46. Ansorge,S., Bank,U., Heimburg,A., Helmuth,M., Koch,G., Tadje,J., Lendeckel,U., Wolke,C., Neubert,K., Faust,J., Fuchs,P., Reinhold,D., Thielitz,A. and Tager,M.
    Recent insights into the role of dipeptidyl aminopeptidase IV (DPIV) and aminopeptidase N (APN) families in immune functions
    Clin Chem Lab Med47, 253-261. PubMed  Europe PubMed DOI
  47. Geiss-Friedlander,R., Parmentier,N., Moller,U., Urlaub,H., Van den Eynde,B.J. and Melchior,F.
    The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides
    J Biol Chem284, 27211-27219. PubMed  Europe PubMed DOI
  48. Pitman,M.R., Sulda,M.L., Kuss,B. and Abbott,C.A.
    Dipeptidyl peptidase 8 and 9 - guilty by association?
    Front Biosci14, 3619-3633. PubMed  Europe PubMed  V
  49. Reinhold,D., Goihl,A., Wrenger,S., Reinhold,A., Kuhlmann,U.C., Faust,J., Neubert,K., Thielitz,A., Brocke,S., Tager,M., Ansorge,S. and Bank,U.
    Role of dipeptidyl peptidase IV (DP IV)-like enzymes in T lymphocyte activation: investigations in DP IV/CD26-knockout mice
    Clin Chem Lab Med47, 268-274. PubMed  Europe PubMed DOI  I
  50. Tang,H.K., Tang,H.Y., Hsu,S.C., Chu,Y.R., Chien,C.H., Shu,C.H. and Chen,X.
    Biochemical properties and expression profile of human prolyl dipeptidase DPP9
    Arch Biochem Biophys485, 120-127. PubMed  Europe PubMed DOI
  51. Wu,J.J., Tang,H.K., Yeh,T.K., Chen,C.M., Shy,H.S., Chu,Y.R., Chien,C.H., Tsai,T.Y., Huang,Y.C., Huang,Y.L., Huang,C.H., Tseng,H.Y., Jiaang,W.T., Chao,Y.S. and Chen,X.
    Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor
    Biochem Pharmacol78, 203-210. PubMed  Europe PubMed DOI  I
  52. Yazbeck,R., Howarth,G.S. and Abbott,C.A.
    Dipeptidyl peptidase inhibitors, an emerging drug class for inflammatory disease?
    Trends Pharmacol Sci30, 600-607. PubMed  Europe PubMed DOI  I
  53. Yu,D.M., Ajami,K., Gall,M.G., Park,J., Lee,C.S., Evans,K.A., McLaughlin,E.A., Pitman,M.R., Abbott,C.A., McCaughan,G.W. and Gorrell,M.D.
    The in vivo expression of dipeptidyl peptidases 8 and 9
    J Histochem Cytochem57, 1025-1040. PubMed  Europe PubMed DOI
    54. 2008
  54. Burkey,B.F., Hoffmann,P.K., Hassiepen,U., Trappe,J., Juedes,M. and Foley,J.E.
    Adverse effects of dipeptidyl peptidases 8 and 9 inhibition in rodents revisited
    Diabetes Obes Metab10, 1057-1061. PubMed  Europe PubMed DOI
  55. Dubois,V., Lambeir,A.M., Van der Veken,P., Augustyns,K., Creemers,J., Chen,X., Scharpe,S. and De Meester,I.
    Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes
    Front Biosci13, 3558-3568. PubMed  Europe PubMed DOI
  56. Schade,J., Stephan,M., Schmiedl,A., Wagner,L., Niestroj,A.J., Demuth,H.U., Frerker,N., Klemann,C., Raber,K.A., Pabst,R. and von Horsten,S.
    Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats
    J Histochem Cytochem56, 147-155. PubMed  Europe PubMed DOI
  57. Van der Veken,P., De Meester,I., Dubois,V., Soroka,A., Van Goethem,S., Maes,M.B., Brandt,I., Lambeir,A.M., Chen,X., Haemers,A., Scharpe,S. and Augustyns,K.
    Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: Identification of dipeptide derived leads
    Bioorg Med Chem Lett18, 4154-4158. PubMed  Europe PubMed DOI  I
  58. Van Goethem,S., Van der Veken,P., Dubois,V., Soroka,A., Lambeir,A.M., Chen,X., Haemers,A., Scharpe,S., De Meester,I. and Augustyns,K.
    Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: Isoindoline containing inhibitors
    Bioorg Med Chem Lett18, 4159-4162. PubMed  Europe PubMed DOI  I
    59. 2007
  59. Frerker,N., Wagner,L., Wolf,R., Heiser,U., Hoffmann,T., Rahfeld,J.U., Schade,J., Karl,T., Naim,H.Y., Alfalah,M., Demuth,H.U. and von Horsten,S.
    Neuropeptide Y (NPY) cleaving enzymes: structural and functional homologues of dipeptidyl peptidase 4
    Peptides28, 257-268. PubMed  Europe PubMed DOI
  60. Maes,M.B., Dubois,V., Brandt,I., Lambeir,A.M., Van der Veken,P., Augustyns,K., Cheng,J.D., Chen,X., Scharpe,S. and De Meester,I.
    Dipeptidyl peptidase 8/9-like activity in human leukocytes
    J Leukoc Biol81, 1252-1257. PubMed  Europe PubMed DOI
  61. Rummey,C. and Metz,G.
    Homology models of dipeptidyl peptidases 8 and 9 with a focus on loop predictions near the active site
    Proteins66, 160-171. PubMed  Europe PubMed DOI  S
  62. Thornberry,N.A. and Weber,A.E.
    Discovery of JANUVIA (Sitagliptin), a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
    Curr Top Med Chem7, 557-568. PubMed  Europe PubMed DOI  I
  63. Van der Veken,P., Haemers,A. and Augustyns,K.
    Prolyl peptidases related to dipeptidyl peptidase IV: potential of specific inhibitors in drug discovery
    Curr Top Med Chem7, 621-635. PubMed  Europe PubMed DOI  V
    64. 2006
  64. [YEAR:13-2-2006]Bjelke,J.R., Christensen,J., Nielsen,P.F., Branner,S., Kanstrup,A.B., Wagtmann,N. and Rasmussen,H.B.
    Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV
    Biochem J396, 391-399. PubMed  Europe PubMed DOI  P
  65. Bjelke,J.R., Kanstrup,A.B. and Rasmussen,H.B.
    Selectivity among dipeptidyl peptidases of the S9b family
    Cell Mol Biol Incl Cyto Enzymol52, 3-7. PubMed  Europe PubMed DOI  P
  66. Yu,D.M., Wang,X.M., McCaughan,G.W. and Gorrell,M.D.
    Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis
    FEBS J273, 2447-2460. PubMed  Europe PubMed DOI
    67. 2005
  67. Lankas,G.R., Leiting,B., Roy,R.S., Eiermann,G.J., Beconi,M.G., Biftu,T., Chan,C.C., Edmondson,S., Feeney,W.P., He,H., Ippolito,D.E., Kim,D., Lyons,K.A., Ok,H.O., Patel,R.A., Petrov,A.N., Pryor,K.A., Qian,X., Reigle,L., Woods,A., Wu,J.K., Zaller,D., Zhang,X., Zhu,L., Weber,A.E. and Thornberry,N.A.
    Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9
    Diabetes54, 2988-2994. PubMed  Europe PubMed DOI  I
    68. 2004
  68. [YEAR:13-7-2004]Ajami,K., Abbott,C.A., McCaughan,G.W. and Gorrell,M.D.
    Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity
    Biochim Biophys Acta1679, 18-28. PubMed  Europe PubMed DOI
    69. 2002
  69. [YEAR:16-10-2002]Olsen,C. and Wagtmann,N.
    Identification and characterization of human DPP9, a novel homologue of dipeptidyl peptidase IV
    Gene299, 185-193. PubMed  Europe PubMed DOI

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