$VAR1 = undef;

Summary for peptidase S09.019: dipeptidyl-peptidase 9

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

Names
MEROPS Namedipeptidyl-peptidase 9
Other namesDPP9, peptidase like H.s. R26984_1
Domain architecture
MEROPS Classification
Classification Clan SC >> Subclan (none) >> Family S9 >> Subfamily B >> S09.019
Holotypedipeptidyl-peptidase 9 (Homo sapiens), Uniprot accession Q86TI2 (peptidase unit: 571-860), MERNUM MER0004923
History Identifier created: MEROPS 5.3 (4 December 2000)
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Activity statushuman: active (Ajami et al., 2004)
mouse: putative
Other databases TREEFAMhttp://www.treefam.org/family/TF313309
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/PScissile bond-/-/-/- (based on 15 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 3 0 0 3 0 0
Pro 0 0 0 13 0 0 1 1
Ala 0 0 2 2 0 0 0 0
Val 0 0 2 0 0 0 0 0
Leu 0 0 0 0 0 1 0 0
Ile 0 0 0 0 1 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 0 0 0 0 0 0 0 3
Tyr 0 0 2 0 1 0 0 0
Trp 0 0 1 0 0 0 0 0
Ser 0 0 0 0 1 0 2 0
Thr 0 0 0 0 0 0 1 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 0 0 1 0 1 0 0 1
Glu 0 0 0 0 1 0 0 0
Lys 0 0 1 0 0 1 1 0
Arg 0 0 1 0 0 0 0 0
His 0 0 2 0 0 0 0 0
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
DPP9 19p13.3 ENSG00000142002 91039 DPP9 608258
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Dpp9 17:C ENSMUSG00000024299 224897 MGI:2443967