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Literature for peptidase S09.007: fibroblast activation protein alpha subunit

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, T Target, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor, L Localization. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Basak,S., Satapathy,S., Shukla,A., Srivastava,N. and Meher,N.
    Fibroblast Activation Protein as a Molecular Handle in Cancer Phototheranostics: Recent Advances
    Mol Pharm PubMed  Europe PubMed DOI  V
  2. Butuzova,D.A., Kulebyakina,M.A., Basalova,N.A. and Efimenko,A.Y.
    Fibroblast Activation Protein Alpha (FAPalpha) as a Promising Target in the Diagnostics and Treatment of Cancer and Fibrotic Diseases: Recent Approaches to Imaging and Assessment of Functional Activity
    Biochemistry (Mosc)90, S135-S135. PubMed  Europe PubMed DOI
  3. Chen,C.C., Wang,L., Wong,A.A.W.L., Lau,W.S., Ng,P., Merkens,H., Benard,F. and Lin,K.S.
    A Novel (68)Ga-Labeled 2-Azabicyclo[3.1.0]Hexane-3-Carbonitrile-Based Fibroblast Activation Protein-Targeted Tracer for Cancer Imaging With Positron Emission Tomography
    J Labelled Comp Radiopharm68, e4143-e4143. PubMed  Europe PubMed DOI
  4. Dong,Y., Hu,X., Liu,W., Hao,Y., Zhou,J., Li,X. and Wang,B.
    Fibroblast activation protein-alpha interacts with CXCL12 to inactivate canonical Wnt signaling and regulate osteoblast differentiation
    Stem Cells PubMed  Europe PubMed DOI
  5. Larrinaga,G., Redrado,M., Loizaga-Iriarte,A., Perez-Fernandez,A., Santos-Martin,A., Angulo,J.C., Fernandez,J.A., Calvo,A. and Lopez,J.I.
    Spatial expression of fibroblast activation protein-alpha in clear cell renal cell carcinomas revealed by multiplex immunoprofiling analysis of the tumor microenvironment
    Cancer Immunol Immunother74, 53-53. PubMed  Europe PubMed DOI
  6. Meng,L., Lin,R., Zhang,J., Li,H., Xia,D., Zhao,Z., Zhuang,R., Huang,L., Zhang,X., Fang,J., Miao,W. and Guo,Z.
    Modification of Asp-Peptide Adapters: Giving the FAP-Targeted Radioligand a "Squirrel Tail"
    J Med Chem68, 6576-6587. PubMed  Europe PubMed DOI
  7. Xu,Z., Sinha,A., Pandya,D.N., Schnicker,N.J. and Wadas,T.J.
    Cryo-electron microscopy reveals a single domain antibody with a unique binding epitope on fibroblast activation protein alpha
    RSC Chem Biol PubMed  Europe PubMed DOI
    8. 2024
  8. Bendre,S., Merkens,H., Kuo,H.T., Ng,P., Wong,A.A.W.L., Lau,W.S., Zhang,Z., Kurkowska,S., Chen,C.C., Uribe,C., Benard,F. and Lin,K.S.
    Development, preclinical evaluation and preliminary dosimetry profiling of SB03178, a first-of-its-kind benzo[h]quinoline-based fibroblast activation protein-alpha-targeted radiotheranostic for cancer imaging and therapy
    Eur J Med Chem268, 116238-116238. PubMed  Europe PubMed DOI
  9. Chen,Y., Du,J., Meng,X., Wu,L.L., Zhang,Q., Han,X., Zhang,L., Wang,Q. and Hu,H.Y.
    A self-immobilizing near-infrared fluorogenic probe for in vivo imaging of fibroblast activation protein-alpha
    Talanta278, 126475-126475. PubMed  Europe PubMed DOI
  10. Du,X., Gu,B., Wang,X., Wang,X., Ji,M., Zhang,J., He,S., Xu,X., Yang,Z. and Song,S.
    Preclinical Evaluation and a Pilot Clinical Positron Emission Tomography Imaging Study of [(68)Ga]Ga-FAPI-FUSCC-II
    Mol Pharm21, 904-915. PubMed  Europe PubMed DOI
  11. Gao,J., Wang,Y., Meng,X., Wang,X., Han,F., Xing,H., Lv,G., Zhang,L., Wu,S., Jiang,X., Yao,Z., Fang,X., Zhang,J. and Bu,W.
    A FAPalpha-activated MRI nanoprobe for precise grading diagnosis of clinical liver fibrosis
    Nat Commun15, 8036-8036. PubMed  Europe PubMed DOI
  12. Hamacher,R., Pabst,K.M., Cheung,P.F., Heilig,C.E., Hullein,J., Liffers,S.T., Borchert,S., Costa,P.F., Schaarschmidt,B.M., Kessler,L., Miera,M.A., Droste,M., Akbulut,M., Falkenhorst,J., Zarrad,F., Kostbade,K., Mavroeidi,I.A., Glimm,H., Umutlu,L., Schuler,M., Hubschmann,D., Bauer,S., Frohling,S., Herrmann,K., Siveke,J.T., Schildhaus,H.U. and Fendler,W.P.
    Fibroblast Activation Protein alpha-Directed Imaging and Therapy of Solitary Fibrous Tumor
    J Nucl Med65, 252-257. PubMed  Europe PubMed DOI
  13. Hisada,K., Kaneda-Nakashima,K., Shirakami,Y., Kadonaga,Y., Saito,A., Watabe,T., Feng,S., Ooe,K., Yin,X., Haba,H., Murakami,M., Toyoshima,A., Cardinale,J., Giesel,F.L. and Fukase,K.
    Comparison Length of Linker in Compound for Nuclear Medicine Targeting Fibroblast Activation Protein as Molecular Target
    Int J Mol Sci25, PubMed  Europe PubMed DOI  I
  14. Morandeau,L., Ioppolo,J.A., Alvarez de Eulate,E., Mohamed,S., Cullen,D., Asad,A.H., Francis,R.J. and Atkinson,J.
    An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use
    J Vis Exp PubMed  Europe PubMed DOI
  15. Nakayama,M., Hope,T.A. and Salavati,A.
    Diagnostic and Therapeutic Application of Fibroblast Activation Protein Inhibitors in Oncologic and Nononcologic Diseases
    Cancer J30, 210-217. PubMed  Europe PubMed DOI  V
  16. Poplawski,S.E., Hallett,R.M., Dornan,M.H., Novakowski,K.E., Pan,S., Belanger,A.P., Nguyen,Q.D., Wu,W., Felten,A.E., Liu,Y., Ahn,S.H., Hergott,V.S., Jones,B., Lai,J.H., McCann,J.A.B. and Bachovchin,W.W.
    Preclinical Development of PNT6555, a Boronic Acid-Based, Fibroblast Activation Protein-alpha (FAP)-Targeted Radiotheranostic for Imaging and Treatment of FAP-Positive Tumors
    J Nucl Med65, 100-108. PubMed  Europe PubMed DOI  I
  17. Thorn,S.L., Spinale,F.G. and Sinusas,A.J.
    Imaging Fibroblast Activation Protein: Direct Visualization of Matrix Proteolytic Activity in Patients Post Myocardial Infarction
    J Am Coll Cardiol PubMed  Europe PubMed DOI
  18. Yu,Z., Jiang,Z., Cheng,X., Yuan,L., Chen,H., Ai,L. and Wu,Z.
    Development of fibroblast activation protein-alpha radiopharmaceuticals: Recent advances and perspectives
    Eur J Med Chem277, 116787-116787. PubMed  Europe PubMed DOI
  19. Zhang,X.L., Xiao,W., Qian,J.P., Yang,W.J., Xu,H., Xu,X.D. and Zhang,G.W.
    The role and application of fibroblast activating protein
    Curr Mol Med24, 1097-1110. PubMed  Europe PubMed DOI
    20. 2023
  20. Bendre,S., Kuo,H.T., Merkens,H., Zhang,Z., Wong,A.A.W.L., Benard,F. and Lin,K.S.
    Synthesis and Preclinical Evaluation of Novel (68)Ga-Labeled (R)-Pyrrolidin-2-yl-boronic Acid-Based PET Tracers for Fibroblast Activation Protein-Targeted Cancer Imaging
    Pharmaceuticals (Basel)16, PubMed  Europe PubMed DOI  I
  21. Castle,A.R., Kang,S.G., Eskandari-Sedighi,G., Wohlgemuth,S., Nguyen,M.A., Drucker,D.J., Mulvihill,E.E. and Westaway,D.
    Beta-endoproteolysis of the cellular prion protein by dipeptidyl peptidase-4 and fibroblast activation protein
    Proc Natl Acad Sci U S A120, e2209815120-e2209815120. PubMed  Europe PubMed DOI
  22. DiMagno,S.G. and Babich,J.W.
    Advanced Fibroblast Activation Protein-Ligand Developments: FAP Imaging Agents: A Review of the Structural Requirements
    PET Clin18, 287-294. PubMed  Europe PubMed DOI
  23. Fan,A., Wu,G., Wang,J., Lu,L., Wang,J., Wei,H., Sun,Y., Xu,Y., Mo,C., Zhang,X., Pang,Z., Pan,Z., Wang,Y., Lu,L., Fu,G., Ma,M., Zhu,Q., Cao,D., Qin,J., Yin,F. and Yue,R.
    Inhibition of fibroblast activation protein ameliorates cartilage matrix degradation and osteoarthritis progression
    Bone Res11, 3-3. PubMed  Europe PubMed DOI
  24. Jin,J., Barnett,J.D., Krishnamachary,B., Mironchik,Y., Luo,C.K., Kobayashi,H. and Bhujwalla,Z.M.
    Evaluating near-infrared photoimmunotherapy for targeting fibroblast activation protein-alpha expressing cells in vitro and in vivo
    Cancer Sci114, 236-246. PubMed  Europe PubMed DOI
  25. Ora,M., Soni,N., Nazar,A.H., Dixit,M., Singh,R., Puri,S., Graham,M.M. and Gambhir,S.
    Fibroblast Activation Protein Inhibitor-Based Radionuclide Therapies: Current Status and Future Directions
    J Nucl Med64, 1001-1008. PubMed  Europe PubMed DOI  V
  26. Rezaei,S., Gharapapagh,E., Dabiri,S., Heidari,P. and Aghanejad,A.
    Theranostics in targeting fibroblast activation protein bearing cells: Progress and challenges
    Life Sci329, 121970-121970. PubMed  Europe PubMed DOI  V
  27. Wang,Z., Wang,J., Lan,T., Zhang,L., Yan,Z., Zhang,N., Xu,Y. and Tao,Q.
    Role and mechanism of fibroblast-activated protein-alpha expression on the surface of fibroblast-like synoviocytes in rheumatoid arthritis
    Front Immunol14, 1135384-1135384. PubMed  Europe PubMed DOI  V
  28. Weiner,L., Fitzgerald,A., Maynard,R., Marcisak,E., Nasir,A., Glasgow,E., Jablonski,S., Van der Veken,P., Pearson,G., Eisman,S., Mace,E. and Fertig,E.
    Fibroblast activation protein regulates natural killer cell migration, extravasation and tumor infiltration
    Res Sq PubMed  Europe PubMed DOI
    29. 2022
  29. An,J., Hou,D., Wang,L., Wang,L., Yang,Y. and Wang,H.
    Fibroblast activation protein-alpha knockdown suppresses prostate cancer cell invasion and proliferation
    Histol Histopathol18430-18430. PubMed  Europe PubMed DOI
  30. Boinapally,S., Lisok,A., Lofland,G., Minn,I., Yan,Y., Jiang,Z., Shin,M.J., Merino,V.F., Zheng,L., Brayton,C., Pomper,M.G. and Banerjee,S.R.
    Hetero-bivalent agents targeting FAP and PSMA
    Eur J Nucl Med Mol Imaging49, 4369-4381. PubMed  Europe PubMed DOI
  31. Cheng,C.S., Yang,P.W., Sun,Y., Song,S.L. and Chen,Z.
    Fibroblast activation protein-based theranostics in pancreatic cancer
    Front Oncol12, 969731-969731. PubMed  Europe PubMed DOI  V
  32. Huang,R., Pu,Y., Huang,S., Yang,C., Yang,F., Pu,Y., Li,J., Chen,L. and Huang,Y.
    FAPI-PET/CT in Cancer Imaging: A Potential Novel Molecule of the Century
    Front Oncol12, 854658-854658. PubMed  Europe PubMed DOI  V
  33. Liu,S.Y., Wang,H. and Nie,G.
    Ultrasensitive Fibroblast Activation Protein-alpha-Activated Fluorogenic Probe Enables Selective Imaging and Killing of Melanoma In Vivo
    ACS Sens7, 1837-1846. PubMed  Europe PubMed DOI
  34. Plescia,J., Hedou,D., Pousse,M.E., Labarre,A., Dufresne,C., Mittermaier,A. and Moitessier,N.
    Modulating the selectivity of inhibitors for prolyl oligopeptidase inhibitors and fibroblast activation protein-alpha for different indications
    Eur J Med Chem240, 114543-114543. PubMed  Europe PubMed DOI
  35. Tagirasa,R. and Yoo,E.
    Role of Serine Proteases at the Tumor-Stroma Interface
    Front Immunol13, 832418-832418. PubMed  Europe PubMed DOI  V
  36. Zhang,L., Ying,W., Sheng,Z., Lv,L., Gao,J., Xue,Y. and Liu,L.
    Bioluminescence imaging of fibroblast activation protein-alpha in vivo and human plasma with highly sensitive probe
    Anal Biochem655, 114859-114859. PubMed  Europe PubMed DOI
  37. Zhao,L., Chen,J., Pang,Y., Fu,K., Shang,Q., Wu,H., Sun,L., Lin,Q. and Chen,H.
    Fibroblast activation protein-based theranostics in cancer research: A state-of-the-art review
    Theranostics12, 1557-1569. PubMed  Europe PubMed DOI
    38. 2021
  38. Altmann,A., Haberkorn,U.A. and Siveke,J.
    The latest developments in imaging fibroblast activation protein (FAP)
    J Nucl Med62, 160-167. PubMed  Europe PubMed DOI
  39. Bughda,R., Dimou,P., D'Souza,R.R. and Klampatsa,A.
    Fibroblast Activation Protein (FAP)-Targeted CAR-T Cells: Launching an Attack on Tumor Stroma
    Immunotargets Ther10, 313-323. PubMed  Europe PubMed DOI  V
  40. Juillerat-Jeanneret,L., Tafelmeyer,P. and Golshayan,D.
    Regulation of Fibroblast Activation Protein-alpha Expression: Focus on Intracellular Protein Interactions
    J Med Chem PubMed  Europe PubMed DOI
  41. Jung,H.J., Nam,E.H., Park,J.Y., Ghosh,P. and Kim,I.S.
    Identification of BR102910 as a selective fibroblast activation protein (FAP) inhibitor
    Bioorg Med Chem Lett37, 127846-127846. PubMed  Europe PubMed DOI  I
  42. Kelly,J.M., Jeitner,T.M., Ponnala,S., Williams,C., Jr., Nikolopoulou,A., DiMagno,S.G. and Babich,J.W.
    A Trifunctional Theranostic Ligand Targeting Fibroblast Activation Protein-alpha (FAPalpha)
    Mol Imaging Biol PubMed  Europe PubMed DOI
  43. Lindner,T., Altmann,A., Giesel,F., Kratochwil,C., Kleist,C., Kramer,S., Mier,W., Cardinale,J., Kauczor,H.U., Jager,D., Debus,J. and Haberkorn,U.
    (18)F-labeled tracers targeting fibroblast activation protein
    EJNMMI Radiopharm Chem6, 26-26. PubMed  Europe PubMed DOI
  44. Moon,E.S., Van Rymenant,Y., Battan,S., De Loose,J., Bracke,A., Van der Veken,P., De Meester,I. and Rosch,F.
    In Vitro Evaluation of the Squaramide-Conjugated Fibroblast Activation Protein Inhibitor-Based Agents AAZTA(5).SA.FAPi and DOTA.SA.FAPi
    Molecules26, PubMed  Europe PubMed DOI  I
  45. Simkova,A., Ormsby,T., Sidej,N., Slavetinska,L.P., Brynda,J., Beranova,J., Sacha,P., Majer,P. and Konvalinka,J.
    Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with alpha-ketoamide warheads
    Eur J Med Chem224, 113717-113717. PubMed  Europe PubMed DOI  I
  46. Sun,M., Yao,S., Fan,L., Fang,Z., Miao,W., Hu,Z. and Wang,Z.
    Fibroblast Activation Protein-alpha Responsive Peptide Assembling Prodrug Nanoparticles for Remodeling the Immunosuppressive Microenvironment and Boosting Cancer Immunotherapy
    Smalle2106296-e2106296. PubMed  Europe PubMed DOI
  47. Xi,C.R., Di Fazio,A., Nadvi,N.A., Xiang,M.S.W., Zhang,H.E., Deshpande,C., Chen,Y., Tabar,M.S., Wang,X.M., Bailey,C.G., McCaughan,G.W., Church,W.B. and Gorrell,M.D.
    An improved production and purification protocol for recombinant soluble human fibroblast activation protein alpha
    Protein Expr Purif181, 105833-105833. PubMed  Europe PubMed DOI
  48. Xin,L., Gao,J., Zheng,Z., Chen,Y., Lv,S., Zhao,Z., Yu,C., Yang,X. and Zhang,R.
    Fibroblast Activation Protein-alpha as a Target in the Bench-to-Bedside Diagnosis and Treatment of Tumors: A Narrative Review
    Front Oncol11, 648187-648187. PubMed  Europe PubMed DOI  V
  49. Yuan,Z., Hu,H., Zhu,Y., Zhang,W., Fang,Q., Qiao,T., Ma,T., Wang,M., Huang,R., Tang,Q., Gao,F., Zou,C., Gao,X., Wang,G. and Wang,X.
    Colorectal cancer cell intrinsic fibroblast activation protein alpha binds to Enolase1 and activates NF-kappaB pathway to promote metastasis
    Cell Death Dis12, 543-543. PubMed  Europe PubMed DOI  K
  50. Zhang,X., Chen,D., Babich,J.W., Green,S.J.E., Deng,X.H. and Rodeo,S.A.
    In Vivo Imaging of Fibroblast Activity Using a 68Ga-Labeled Fibroblast Activation Protein Alpha (FAP-alpha) Inhibitor: Study in a Mouse Rotator Cuff Repair Model
    J Bone Joint Surg Am103, e40-e40. PubMed  Europe PubMed DOI
    51. 2020
  51. Cho,J.M., Yang,E.H., Quan,W., Nam,E.H. and Cheon,H.G.
    Discovery of a novel fibroblast activation protein (FAP) inhibitor, BR103354, with anti-diabetic and anti-steatotic effects
    Sci Rep10, 21280-21280. PubMed  Europe PubMed DOI  I
  52. Fitzgerald,A.A. and Weiner,L.M.
    The role of fibroblast activation protein in health and malignancy
    Cancer Metastasis Rev PubMed  Europe PubMed DOI  V
  53. Li,F., Wu,X., Sun,Z., Cai,P., Wu,L. and Li,D.
    Fibroblast Activation Protein-alpha Expressing Fibroblasts Promote Lymph Node Metastasis in Esophageal Squamous Cell Carcinoma
    Onco Targets Ther13, 8141-8148. PubMed  Europe PubMed DOI
  54. Simkova,A., Busek,P., Sedo,A. and Konvalinka,J.
    Molecular recognition of fibroblast activation protein for diagnostic and therapeutic applications
    Biochim Biophys Acta Proteins Proteom140409-140409. PubMed  Europe PubMed DOI  I
  55. Solano-Iturri,J.D., Beitia,M., Errarte,P., Calvete-Candenas,J., Etxezarraga,M.C., Loizate,A., Echevarria,E., Badiola,I. and Larrinaga,G.
    Altered expression of fibroblast activation protein-alpha (FAP) in colorectal adenoma-carcinoma sequence and in lymph node and liver metastases
    Aging (Albany NY)12, PubMed  Europe PubMed DOI
  56. Teng,C., Zhang,B., Yuan,Z., Kuang,Z., Chai,Z., Ren,L., Qin,C., Yang,L., Han,X. and Yin,L.
    Fibroblast activation protein-alpha-adaptive micelles deliver anti-cancer drugs and reprogram stroma fibrosis
    Nanoscale12, 23756-23767. PubMed  Europe PubMed DOI  I
  57. Wei,H., Xu,Y., Wang,Y., Xu,L., Mo,C., Li,L., Shen,B., Sun,Y., Cheng,P., Yang,L., Pang,Y., Qin,A., Cao,Y., Morrison,S.J. and Yue,R.
    Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target
    Cell Rep33, 108252-108252. PubMed  Europe PubMed DOI
    58. 2019
  58. Bracke,A., Van Elzen,R., Van der Veken,P., Augustyns,K., De Meester,I. and Lambeir,A.M.
    The development and validation of a combined kinetic fluorometric activity assay for fibroblast activation protein alpha and prolyl oligopeptidase in plasma
    Clin Chim Acta495, 154-160. PubMed  Europe PubMed DOI  A
  59. De Decker,A., Vliegen,G., Van Rompaey,D., Peeraer,A., Bracke,A., Verckist,L., Jansen,K., Geiss-Friedlander,R., Augustyns,K., De Winter,H., De Meester,I., Lambeir,A.M. and Van der Veken,P.
    Novel small molecule-derived, highly selective substrates for fibroblast activation protein (FAP)
    ACS Med Chem Lett10, 1173-1179. PubMed  Europe PubMed DOI  A
  60. Hintz,H.M., Cowan,A.E., Shapovalova,M. and Lebeau,A.M.
    Development of a cross-reactive monoclonal antibody for detecting the tumor stroma
    Bioconjug Chem30, 1466-1476. PubMed  Europe PubMed DOI
  61. Lay,A.J., Zhang,H.E., McCaughan,G.W. and Gorrell,M.D.
    Fibroblast activation protein in liver fibrosis
    Front Biosci (Landmark Ed)24, 1-17. PubMed  Europe PubMed
  62. Lin,Y., Ma,Z., Li,Z., Gao,Y., Qin,X., Zhang,Z., Wang,G., Du,L. and Li,M.
    Bioluminescent probe for monitoring endogenous fibroblast activation protein-alpha
    Anal Chem91, 14873-14878. PubMed  Europe PubMed DOI  L
  63. Loktev,A., Lindner,T., Burger,E.M., Altmann,A., Giesel,F., Kratochwil,C., Debus,J., Marme,F., Jager,D., Mier,W. and Haberkorn,U.
    Development of fibroblast activation protein-targeted radiotracers with improved tumor retention
    J Nucl Med60, 1421-1429. PubMed  Europe PubMed DOI  I
  64. Plescia,J., De Cesco,S., Patrascu,M.B., Kurian,J., Di Trani,J., Dufresne,C., Wahba,A.S., Janmamode,N., Mittermaier,A.K. and Moitessier,N.
    Integrated synthetic, biophysical, and computational investigations of covalent inhibitors of prolyl oligopeptidase and fibroblast activation protein alpha
    J Med Chem62, 7874-7884. PubMed  Europe PubMed DOI  I
  65. Zhang,H.E., Hamson,E.J., Koczorowska,M.M., Tholen,S., Chowdhury,S., Bailey,C.G., Lay,A.J., Twigg,S.M., Lee,Q., Roediger,B., Biniossek,M.L., O'Rourke,M.B., McCaughan,G.W., Keane,F.M., Schilling,O. and Gorrell,M.D.
    Identification of novel natural substrates of fibroblast activation protein-alpha by differential degradomics and proteomics
    Mol Cell Proteomics18, 65-85. PubMed  Europe PubMed DOI  P
    66. 2018
  66. Busek,P., Mateu,R., Zubal,M., Kotackova,L. and Sedo,A.
    Targeting fibroblast activation protein in cancer - prospects and caveats
    Front Biosci (Landmark Ed)23, 1933-1968. PubMed  Europe PubMed  T
  67. Chai,X.P., Sun,G.L., Fang,Y.F., Hu,L.H., Liu,X. and Zhang,X.W.
    Tumor-targeting efficacy of a BF211 prodrug through hydrolysis by fibroblast activation protein-alpha
    Acta Pharmacol Sin39, 415-424. PubMed  Europe PubMed DOI
  68. Feng,F., Chen,X., Li,G., Liang,S., Hong,Z. and Wang,H.F.
    Afterglow resonance energy transfer inhibition for fibroblast activation protein-alpha assay
    ACS Sens3, 1846-1854. PubMed  Europe PubMed DOI  A
  69. Huang,S., Zhang,Y., Zhong,J., Pan,Y., Cai,S. and Xu,J.
    Toxicological profile and safety pharmacology of a single dose of fibroblast activation protein-alpha-based doxorubicin prodrug: in-vitro and in-vivo evaluation
    Anticancer Drugs29, 253-261. PubMed  Europe PubMed DOI
  70. Lindner,T., Loktev,A., Altmann,A., Giesel,F., Kratochwil,C., Debus,J., Jager,D., Mier,W. and Haberkorn,U.
    Development of quinoline-based theranostic ligands for the targeting of fibroblast activation protein
    J Nucl Med59, 1415-1422. PubMed  Europe PubMed DOI  I
  71. Pure,E. and Blomberg,R.
    Pro-tumorigenic roles of fibroblast activation protein in cancer: back to the basics
    Oncogene37, 4343-4357. PubMed  Europe PubMed DOI  V
    72. 2017
  72. Bainbridge,T.W., Dunshee,D.R., Kljavin,N.M., Skelton,N.J., Sonoda,J. and Ernst,J.A.
    Selective homogeneous assay for circulating endopeptidase fibroblast activation protein (FAP)
    Sci Rep7, 12524-12524. PubMed  Europe PubMed DOI  A
  73. Dvorakova,P., Busek,P., Knedlik,T., Schimer,J., Etrych,T., Kostka,L., Stollinova Sromova,L., Subr,V., Sacha,P., Sedo,A. and Konvalinka,J.
    Inhibitor-decorated polymer conjugates targeting fibroblast activation protein
    J Med Chem60, 8385-8393. PubMed  Europe PubMed DOI  I
  74. Juillerat-Jeanneret,L., Tafelmeyer,P. and Golshayan,D.
    Fibroblast activation protein-alpha in fibrogenic disorders and cancer: more than a prolyl-specific peptidase?
    Expert Opin Ther Targets21, 977-991. PubMed  Europe PubMed DOI  T
  75. Wang,J., Li,Q., Li,X., Yuan,W., Huang,S., Cai,S. and Xu,J.
    A novel FAPalpha-based Z-Gly-Pro epirubicin prodrug for improving tumor-targeting chemotherapy
    Eur J Pharmacol815, 166-172. PubMed  Europe PubMed DOI
  76. Wu,X., Wang,Y., Xu,J., Luo,T., Deng,J. and Hu,Y.
    MM-BMSCs induce naive CD4+ T lymphocytes dysfunction through fibroblast activation protein alpha
    Oncotarget8, 52614-52628. PubMed  Europe PubMed DOI  I
    77. 2016
  77. Akinboye,E.S., Brennen,W.N., Rosen,D.M., Bakare,O. and Denmeade,S.R.
    Iterative design of emetine-based prodrug targeting fibroblast activation protein (FAP) and dipeptidyl peptidase IV DPPIV using a tandem enzymatic activation strategy
    Prostate76, 703-714. PubMed  Europe PubMed DOI
  78. Dunshee,D.R., Bainbridge,T.W., Kljavin,N.M., Zavala-Solorio,J., Schroeder,A.C., Chan,R., Corpuz,R., Wong,M., Zhou,W., Deshmukh,G., Ly,J., Sutherlin,D.P., Ernst,J.A. and Sonoda,J.
    Fibroblast activation protein cleaves and inactivates fibroblast growth factor 21
    J Biol Chem291, 5986-5996. PubMed  Europe PubMed DOI  T
  79. Fan,M.H., Zhu,Q., Li,H.H., Ra,H.J., Majumdar,S., Gulick,D.L., Jerome,J.A., Madsen,D.H., Christofidou-Solomidou,M., Speicher,D.W., Bachovchin,W.W., Feghali-Bostwick,C. and Pure,E.
    Fibroblast activation protein (FAP) accelerates collagen degradation and clearance from lungs in mice
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  80. Gillum,M.P. and Potthoff,M.J.
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