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Literature for peptidase S08.054: endopeptidase K

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

(Topics flags: S Structure, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Rybacki,B., Wysocki,W., Zajkowski,T., Brodzik,R. and Krawczyk,B.
    Effects of Microgravity, Hypergravity, and Ionizing Radiation on the Enzymatic Activity of Proteinase K
    Molecules (2026) 31 PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2025
  2. Nagel,L., Grossbach,J., Cappelletti,V., Dorig,C., Picotti,P. and Beyer,A.
    Analysis of limited proteolysis-coupled mass spectrometry data
    Mol Cell Proteomics (2025) , 100934-100934. PubMed  Europe PubMed DOI
  3. Shrestha,S., Snowdon,M. and Levin,D.B.
    Enzymatic Degradation of PLA: Preferential Degradation of the Amorphous Fraction
    Polymers (Basel) (2025) 17 PubMed  Europe PubMed DOI  PMC  EPMC
  4. Sun,H., Sun,S., Wang,H., Cheng,K., Zhou,Y., Wang,X., Gao,S., Mo,J., Li,S., Lin,H. and Wang,P.
    Phenylboronic acid-modified carbon dot-proteinase K nanohybrids for enhanced photodynamic therapy against bacterial biofilm infections
    Acta Biomater (2025) PubMed  Europe PubMed DOI
  5. Yang,Y., Zhang,B. and Zhang,J.
    Dynamic catalytic domain plasticity governs substrate specificity in industrial serine proteases: Structural and functional implications
    Int J Biol Macromol (2025) 331, 148374-148374. PubMed  Europe PubMed DOI
  6. Zaman,H., Saeed,A., Ismail,H. and Rashid,M.
    Unveiling the cyclopropyl appended acyl thiourea derivatives as antimicrobial, alpha-amylase and proteinase K inhibitors: Design, synthesis, biological evaluation, molecular docking, DFT and ADMET studies
    Arch Biochem Biophys (2025) 765, 110304-110304. PubMed  Europe PubMed DOI  I
    7. 2024
  7. Duan,R., Wang,S., Li,Z., Zhang,W., Wu,J., Jiang,Y., Lin,Q., Yuan,P., Yue,X., Yao,Y., Xiao,X., Xiao,Y. and Wang,Z.
    Computer-assisted semi-rational design enhanced the enzymatic activity and protein stability of Proteinase K in calcium-free conditions
    Biochem Biophys Res Commun (2024) 721, 150109-150109. PubMed  Europe PubMed DOI
  8. Gobel,G., Muller,F., Talke,A., Ahnert,U. and Lisdat,F.
    Qualitative and quantitative protease activity tests based on protein degradation in three-dimensional structures
    Bioelectrochemistry (2024) 160, 108775-108775. PubMed  Europe PubMed DOI
  9. Jiang,X., Yeung,D., Liu,Y., Spicer,V., Afshari,H., Lao,Y., Lin,F., Krokhin,O. and Zahedi,R.P.
    Accelerating Proteomics Using Broad Specificity Proteases
    J Proteome Res (2024) 23, 1360-1369. PubMed  Europe PubMed DOI
  10. Yang,Y., Zhang,B. and Zhang,J.
    Probing the binding mode and interactions of proteinase K and glutathione: molecular simulation and experiments
    Soft Matter (2024) PubMed  Europe PubMed DOI
  11. Zaman,H., Saeed,A., Ismail,H., Anwaar,S., Latif,M., Hashmi,M.Z. and El-Seedi,H.R.
    Novel pyrimidine linked acyl thiourea derivatives as potent alpha-amylase and proteinase K inhibitors: design, synthesis, molecular docking and ADME studies
    RSC Adv (2024) 14, 33235-33246. PubMed  Europe PubMed DOI  PMC  EPMC  I
    12. 2023
  12. Liu,K., Zhang,Y., Zhang,W., Liu,L. and Yu,Z.
    A Study on the Interactions of Proteinase K with Myricetin and Myricitrin by Multi-Spectroscopy and Molecular Modeling
    Int J Mol Sci (2023) 24 PubMed  Europe PubMed DOI  PMC  EPMC  I
  13. Yang,J., Chu,N. and Chen,X.
    Preparation of Polyoxometalate-Based Composite by Solidification of Highly Active Cobalt-Containing Polytungstate on Polymeric Ionic Liquid for the Efficient Isolation of Proteinase K
    Molecules (2023) 28 PubMed  Europe PubMed DOI  PMC  EPMC
    14. 2022
  14. Li,R., Liu,Z., Jiang,F., Zhao,Y., Yang,G. and Hong,L.
    Enhancement of thermal stability of proteinase K by biocompatible cholinium-based ionic liquids
    Phys Chem Chem Phys (2022) 24, 13057-13065. PubMed  Europe PubMed DOI
  15. Martynowycz,M.W., Clabbers,M.T.B., Hattne,J. and Gonen,T.
    Ab initio phasing macromolecular structures using electron-counted MicroED data
    Nat Methods (2022) 19, 724-729. PubMed  Europe PubMed DOI  PMC  EPMC
  16. Paudyal,S., Sigdel,G., Shah,S.K., Sharma,S.K., Grubb,J.D., Micic,M., Caseli,L. and Leblanc,R.M.
    Interfacial behavior of Proteinase K enzyme at air-saline subphase
    J Colloid Interface Sci (2022) 616, 701-708. PubMed  Europe PubMed DOI
  17. Xu,C., Battig,A., Schartel,B., Siegel,R., Senker,J., von der Forst,I., Unverzagt,C., Agarwal,S., Moglich,A. and Greiner,A.
    Investigation of the Thermal Stability of Proteinase K for the Melt Processing of Poly(l-lactide)
    Biomacromolecules (2022) 23, 4841-4850. PubMed  Europe PubMed DOI  PMC  EPMC
    18. 2021
  18. Beklemishev,A.B., Pykhtina,M.B., Kulikov,Y.M., Goryachkovskaya,T.N., Bochkov,D.V., Sergeeva,S.V., Vasileva,A.R., Romanov,V.P., Novikova,D.S. and Peltek,S.E.
    Creation of a recombinant Komagataella phaffii strain, a producer of proteinase K from Tritirachium album
    Vavilovskii Zhurnal Genet Selektsii (2021) 25, 882-888. PubMed  Europe PubMed DOI  PMC  EPMC
  19. Dong,Z., An,L., Lu,M., Tang,M., Chen,H., Huang,X., Hou,Y., Shen,G., Zhang,X., Zhang,Y., Xia,Q. and Zhao,P.
    SPINK7 Recognizes Fungi and Initiates Hemocyte-Mediated Immune Defense Against Fungal Infections
    Front Immunol (2021) 12, 735497-735497. PubMed  Europe PubMed DOI  PMC  EPMC
  20. Zhao,Y., Li,D., Bai,X., Luo,M., Feng,Y., Zhao,Y., Ma,F. and Yang,G.Y.
    Improved thermostability of proteinase K and recognizing the synergistic effect of Rosetta and FoldX approaches
    Protein Eng Des Sel (2021) 34 PubMed  Europe PubMed DOI
    21. 2020
  21. Dau,T., Bartolomucci,G. and Rappsilber,J.
    Proteomics Using Protease Alternatives to Trypsin Benefits from Sequential Digestion with Trypsin
    Anal Chem (2020) 92, 9523-9527. PubMed  Europe PubMed DOI  PMC  EPMC
  22. Ren,Y., Luo,H., Huang,H., Hakulinen,N., Wang,Y., Wang,Y., Su,X., Bai,Y., Zhang,J., Yao,B., Wang,G. and Tu,T.
    Improving the catalytic performance of proteinase K from Parengyodontium album for use in feather degradation
    Int J Biol Macromol (2020) 154, 1586-1595. PubMed  Europe PubMed DOI
  23. Richards,L.S., Millan,C., Miao,J., Martynowycz,M.W., Sawaya,M.R., Gonen,T., Borges,R.J., Uson,I. and Rodriguez,J.A.
    Fragment-based determination of a proteinase K structure from MicroED data using ARCIMBOLDO_SHREDDER
    Acta Crystallogr D Struct Biol (2020) 76, 703-712. PubMed  Europe PubMed DOI  PMC  EPMC
    24. 2019
  24. Ahmad,M.S., Akbar,Z. and Choudhary,M.I.
    Insight into the binding affinity of thiourea in the calcium binding pocket of proteinase K, through high resolution X-ray crystallography
    Bioorg Chem (2019) , 103443-103443. PubMed  Europe PubMed DOI
    25. 2017
  25. Du,X., Sang,P., Xia,Y.L., Li,Y., Liang,J., Ai,S.M., Ji,X.L., Fu,Y.X. and Liu,S.Q.
    Comparative thermal unfolding study of psychrophilic and mesophilic subtilisin-like serine proteases by molecular dynamics simulations
    J Biomol Struct Dyn (2017) 35, 1500-1517. PubMed  Europe PubMed DOI
  26. Masuda,T., Suzuki,M., Inoue,S., Song,C., Nakane,T., Nango,E., Tanaka,R., Tono,K., Joti,Y., Kameshima,T., Hatsui,T., Yabashi,M., Mikami,B., Nureki,O., Numata,K., Iwata,S. and Sugahara,M.
    Atomic resolution structure of serine protease proteinase K at ambient temperature
    Sci Rep (2017) 7, 45604-45604. PubMed  Europe PubMed DOI  PMC  EPMC  S
  27. Singh,N. and Bhattacharyya,D.
    Cholesterol and its derivatives reversibly inhibit proteinase K
    J Cell Physiol (2017) 232, 596-609. PubMed  Europe PubMed DOI
    28. 2016
  28. Sang,P., Yang,Q., Du,X., Yang,N., Yang,L.Q., Ji,X.L., Fu,Y.X., Meng,Z.H. and Liu,S.Q.
    Effect of the solvent temperatures on dynamics of serine protease proteinase K
    Int J Mol Sci (2016) 17, 254-254. PubMed  Europe PubMed DOI
  29. Yang,H., Zhai,C., Yu,X., Li,Z., Tang,W., Liu,Y., Ma,X., Zhong,X., Li,G., Wu,D. and Ma,L.
    High-level expression of proteinase K from Tritirachium album Limber in Pichia pastoris using multi-copy expression strains
    Protein Expr Purif (2016) 122, 38-44. PubMed  Europe PubMed DOI  E
    30. 2015
  30. Kuchler,A., Bleich,J.N., Sebastian,B., Dittrich,P.S. and Walde,P.
    Stable and Simple Immobilization of Proteinase K Inside Glass Tubes and Microfluidic Channels
    ACS Appl Mater Interfaces (2015) 7, 25970-25980. PubMed  Europe PubMed DOI
  31. Silva,C.J., Vazquez-Fernandez,E., Onisko,B. and Requena,J.R.
    Proteinase K and the structure of PrPSc: the good, the bad and the ugly
    Virus Res (2015) 207, 120-126. PubMed  Europe PubMed DOI
    32. 2014
  32. Qasim,M.A.
    Specificity of proteinase K at P2 to P3' sub-sites and its comparison to other serine proteases
    Protein Pept Lett (2014) 21, 164-170. PubMed  Europe PubMed  P
    33. 2013
  33. Ageitos,J.M., Baker,P.J., Sugahara,M. and Numata,K.
    Proteinase K-catalyzed synthesis of linear and star oligo(l-phenylalanine) conjugates
    Biomacromolecules (2013) 14, 3635-3642. PubMed  Europe PubMed DOI
    34. 2012
  34. Kore,A.R. and Shanmugasundaram,M.
    Efficient synthesis of new peptidyl chloromethyl ketones for the application of proteinase K inhibitors
    Synth Commun (2012) 42, 40-45. DOI  I
  35. Petrotchenko,E.V., Serpa,J.J., Hardie,D.B., Berjanskii,M., Suriyamongkol,B.P., Wishart,D.S. and Borchers,C.H.
    Use of proteinase K nonspecific digestion for selective and comprehensive identification of interpeptide cross-links: application to prion proteins
    Mol Cell Proteomics (2012) 11, M111-M111. PubMed  Europe PubMed DOI
  36. Saenger,W.
    Proteinase K
    [ISSN:978-0-12-407742-3] (2012) 3, 3240-3242. DOI
  37. Sommer,C., Hertel,T.C., Schmelzer,C.E. and Pietzsch,M.
    Investigations on the activation of recombinant microbial pro-transglutaminase: in contrast to proteinase K, dispase removes the histidine-tag
    Amino Acids (2012) 42, 997-1006. PubMed  Europe PubMed DOI
    38. 2011
  38. Chatake,T., Ishikawa,T., Yanagisawa,Y., Yamada,T., Tanaka,I., Fujiwara,S. and Morimoro,Y.
    High-resolution X-ray study of the effects of deuteration on crystal growth and the crystal structure of proteinase K
    Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 67, 1334-1338. PubMed  Europe PubMed DOI  PMC  EPMC  S
  39. Liu,S.Q., Tao,Y., Meng,Z.H., Fu,Y.X. and Zhang,K.Q.
    The effect of calciums on molecular motions of proteinase K
    J Mol Model (2011) 17, 289-300. PubMed  Europe PubMed DOI
  40. Panek,J.J., Mazzarello,R., Novic,M. and Jezierska-Mazzarello,A.
    Impact of mercury(II) on proteinase K catalytic center: investigations via classical and Born-Oppenheimer molecular dynamics
    Mol Divers (2011) 15, 215-226. PubMed  Europe PubMed DOI
  41. Tiberti,M. and Papaleo,E.
    Dynamic properties of extremophilic subtilisin-like serine-proteases
    J Struct Biol (2011) 174, 69-83. PubMed  Europe PubMed DOI  S
    42. 2010
  42. Kore,A.R., Shanmugasundaram,M., Charles,I. and Hoang,Q.
    Synthesis and biological evaluation of modified pentapeptides as potent proteinase K inhibitors
    Bioorg Med Chem Lett (2010) 20, 2750-2754. PubMed  Europe PubMed DOI  I
  43. Kore,A.R. and Shanmugasundaram,M.
    Design, synthesis and inhibitory effect of pentapeptidyl chloromethyl ketones on proteinase K
    Bioorg Med Chem (2010) 18, 8383-8387. PubMed  Europe PubMed DOI  I
  44. Tao,Y., Rao,Z.H. and Liu,S.Q.
    Insight derived from molecular dynamics simulation into substrate-induced changes in protein motions of proteinase K
    J Biomol Struct Dyn (2010) 28, 143-158. PubMed  Europe PubMed DOI
    45. 2009
  45. Gardberg,A.S., Blakeley,M.P. and Myles,D.A.
    A preliminary neutron crystallographic study of proteinase K at pD 6.5
    Acta Crystallograph Sect F Struct Biol Cryst Commun (2009) 65, 184-187. PubMed  Europe PubMed DOI  PMC  EPMC  S
  46. Kore,A.R., Shanmugasundaram,M., Hoang,Q., Kuo,M., Chapman,L.M. and Chen,H.H.
    Synthesis and application of MeOSuc-Ala-Ala-Pro-Phe-CH2Cl as potent proteinase K inhibitor
    Bioorg Med Chem Lett (2009) 19, 1296-1300. PubMed  Europe PubMed DOI  I
  47. Larson,S.B., Day,J.S., Nguyen,C., Cudney,R. and McPherson,A.
    High-resolution structure of proteinase K cocrystallized with digalacturonic acid
    Acta Crystallograph Sect F Struct Biol Cryst Commun (2009) 65, 192-198. PubMed  Europe PubMed DOI  PMC  EPMC  S
  48. Tomar,R., Dubey,V.K. and Jagannadham,M.V.
    Effect of alkyl alcohols on partially unfolded state of proteinase K: differential stability of alpha-helix and beta-sheet rich regions of the enzyme
    Biochimie (2009) 91, 951-960. PubMed  Europe PubMed DOI
    49. 2006
  49. Georgieva,D., Genov,N., Voelter,W. and Betzel,C.
    Catalytic efficiencies of alkaline proteinases from microorganisms
    Z Naturforsch C J Biosci (2006) 61, 445-452.
    50. 2004
  50. [YEAR:24-12-2004]Georgieva,D., Rypniewski,W., Echner,H., Perbandt,M., Koker,M., Clos,J., Redecke,L., Bredehorst,R., Voelter,W., Genov,N. and Betzel,C.
    Synthetic human prion protein octapeptide repeat binds to the proteinase K active site
    Biochem Biophys Res Commun (24-12-2004) 325, 1406-1411. PubMed  Europe PubMed DOI  S
  51. Saenger,W.
    Proteinase K
    [ISSN:0-12-079610-4] (2004) 2, 1829-1831.  V
    52. 2001
  52. [YEAR:13-3-2001]Betzel,C., Gourinath,S., Kumar,P., Kaur,P., Perbandt,M., Eschenburg,S. and Singh,T.P.
    Structure of a serine protease proteinase K from Tritirachium album limber at 0.98 A resolution
    Biochemistry (13-3-2001) 40, 3080-3088. PubMed  Europe PubMed DOI  S
  53. Gourinath,S., Degenhardt,M., Eschenburg,S., Moore,K., DeLucas,L.J., Betzel,C. and Singh,T.P.
    Mercury induced modifications in the stereochemistry of the active site through Cys-73 in a serine protease - crystal structure of the complex of a partially modified proteinase K with mercury at 1.8 A resolution
    Indian J Biochem Biophys (2001) 38, 298-302. PubMed  Europe PubMed  S
  54. Singh,R.K., Gourinath,S., Sharma,S., Roy,I., Gupta,M.N., Betzel,C., Srinivasan,A. and Singh,T.P.
    Enhancement of enzyme activity through three-phase partitioning: crystal structure of a modified serine proteinase at 1.5 A resolution
    Protein Eng (2001) 14, 307-313. PubMed  Europe PubMed  S
    55. 2000
  55. Gupta,M.N., Tyagi,R., Sharma,S., Karthikeyan,S. and Singh,T.P.
    Enhancement of catalytic efficiency of enzymes through exposure to anhydrous organic solvent at 70 degrees C. Three-dimensional structure of a treated serine proteinase at 2.2 A resolution
    Proteins (2000) 39, 226-234. PubMed  Europe PubMed DOI  S
    56. 1998
  56. Singh,T.P., Sharma,S., Karthikeyan,S., Betzel,C. and Bhatia,K.L.
    Crystal structure of a complex formed between proteolytically-generated lactoferrin fragment and proteinase K
    Proteins (1998) 33, 30-38. PubMed  Europe PubMed DOI  S
    57. 1996
  57. Borhan,B., Hammock,B., Seifert,J. and Wilson,B.W.
    Methyl and phenyl esters and thioesters of carboxylic acids as surrogate substrates for microassay of proteinase K esterase activity
    Anal Bioanal Chem (1996) 354, 490-492. PubMed  Europe PubMed DOI
  58. Saxena,A.K., Singh,T.P., Peters,K., Fittkau,S., Visanji,M., Wilson,K.S. and Betzel,C.
    Structure of a ternary complex of proteinase K, mercury, and a substrate-analogue hexa-peptide at 2.2 A resolution
    Proteins (1996) 25, 195-201. PubMed  Europe PubMed DOI  S
  59. Saxena,A.K., Singh,T.P., Peters,K., Fittkau,S. and Betzel,C.
    Strategy to design peptide inhibitors: structure of a complex of proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5A resolution
    Protein Sci (1996) 5, 2453-2458. PubMed  Europe PubMed DOI  PMC  EPMC  S  I
    60. 1995
  60. Ellison,D., Hinton,J., Hubbard,S.J. and Beynon,R.J.
    Limited proteolysis of native proteins: the interaction between avidin and proteinase K
    Protein Sci (1995) 4, 1337-1345. PubMed  Europe PubMed DOI  PMC  EPMC  P
  61. Genov,N., Filippi,B., Dolashka,P., Wilson,K.S. and Betzel,C.
    Stability of subtilisins and related proteinases (subtilases)
    Int J Pept Protein Res (1995) 45, 391-400. PubMed  Europe PubMed
    62. 1994
  62. Muller,A., Hinrichs,W., Wolf,W.M. and Saenger,W.
    Crystal structure of calcium-free proteinase K at 1.5-A resolution
    J Biol Chem (1994) 269, 23108-23111. PubMed  Europe PubMed  S
  63. [YEAR:21-3-1994]Pal,G.P., Kavounis,C.A., Jany,K.D. and Tsernoglou,D.
    The three-dimensional structure of the complex of proteinase K with its naturally occurring protein inhibitor, PKI3
    FEBS Lett (21-3-1994) 341, 167-170. PubMed  Europe PubMed DOI  S
    64. 1993
  64. Betzel,C., Singh,T.P., Visanji,M., Peters,K., Fittkau,S., Saenger,W. and Wilson,K.S.
    Structure of the complex of proteinase K with a substrate analogue hexapeptide inhibitor at 2.2-A resolution
    J Biol Chem (1993) 268, 15854-15858. PubMed  Europe PubMed  S
  65. [YEAR:15-12-1993]Muller,A. and Saenger,W.
    Studies on the inhibitory action of mercury upon proteinase K
    J Biol Chem (15-12-1993) 268, 26150-26154. PubMed  Europe PubMed
  66. Sweeney,P.J. and Walker,J.M.
    Proteinase K (EC 3.4.21.14)
    Methods Mol Biol (1993) 16, 305-311. PubMed  Europe PubMed DOI
    67. 1992
  67. Bech,L.M., Branner,S., Hastrup,S. and Breddam,K.
    Introduction of a free cysteinyl residue at position 68 in the subtilisin Savinase, based on homology with proteinase K
    FEBS Lett (1992) 297, 164-166. PubMed  Europe PubMed DOI
  68. [YEAR:1-2-1992]Dolashka,P., Dimov,I., Genov,N., Svendsen,I., Wilson,K.S. and Betzel,C.
    Fluorescence properties of native and photooxidised proteinase K: the X-ray model in the region of the two tryptophans
    Biochim Biophys Acta (1-2-1992) 1118, 303-312. PubMed  Europe PubMed DOI  I
    69. 1991
  69. Samal,B.B., Karan,B., Parker,C. and Stabinsky,Y.
    Isolation and thermal stability studies of two novel serine proteinases from the fungus Tritirachium album Limber
    Enzyme Microb Technol (1991) 13, 66-70. PubMed  Europe PubMed DOI
  70. Wolf,W.M., Bajorath,J., Muller,A., Raghunathan,S., Singh,T.P., Hinrichs,W. and Saenger,W.
    Inhibition of proteinase K by methoxysuccinyl-Ala-Ala-Pro-Ala-chloromethyl ketone. An x-ray study at 2.2-A resolution
    J Biol Chem (1991) 266, 17695-17699. PubMed  Europe PubMed
    71. 1990
  71. Betzel,C., Teplyakov,A.V., Harutyunyan,E.H., Saenger,W. and Wilson,K.S.
    Thermitase and proteinase K: a comparison of the refined three-dimensional structures of the native enzymes
    Protein Eng (1990) 3, 161-172. PubMed  Europe PubMed  S
    72. 1989
  72. Cerovsky,V. and Martinek,K.
    Amino acids and peptides. Part CCXII. Peptide synthesis catalyzed by native proteinase K in water-miscible organic solvents with low water content
    Collect Czech Chem Commun (1989) 54, 2027-2041.
  73. [YEAR:15-1-1989]Gunkel,F.A. and Gassen,H.G.
    Proteinase K from Tritirachium album Limber. Characterization of the chromosomal gene and expression of the cDNA in Escherichia coli
    Eur J Biochem (15-1-1989) 179, 185-194. PubMed  Europe PubMed
    74. 1988
  74. [YEAR:18-5-1988]Bajorath,J., Saenger,W. and Pal,G.P.
    Autolysis and inhibition of proteinase K, a subtilisin-related serine proteinase isolated from the fungus Tritirachium album Limber
    Biochim Biophys Acta (18-5-1988) 954, 176-182. PubMed  Europe PubMed
  75. [YEAR:15-9-1988]Bajorath,J., Hinrichs,W. and Saenger,W.
    The enzymatic activity of proteinase K is controlled by calcium
    Eur J Biochem (15-9-1988) 176, 441-447. PubMed  Europe PubMed
  76. Betzel,C., Pal,G.P. and Saenger,W.
    Three-dimensional structure of proteinase K at 0.15-nm resolution
    Eur J Biochem (1988) 178, 155-171. PubMed  Europe PubMed  S
  77. Betzel,C., Bellemann,M., Pal,G.P., Bajorath,J., Saenger,W. and Wilson,K.S.
    X-ray and model-building studies on the specificity of the active site of proteinase K
    Proteins (1988) 4, 157-164. PubMed  Europe PubMed DOI
  78. Betzel,C., Pal,G.P. and Saenger,W.
    Synchrotron X-ray data collection and restrained least-squares refinement of the crystal structure of proteinase K at 1.5 A resolution
    Acta Crystallogr B (1988) 44, 163-172. PubMed  Europe PubMed DOI  S
    79. 1986
  79. [YEAR:3-3-1986]Betzel,C., Pal,G.P., Struck,M., Jany,K.D. and Saenger,W.
    Active-site geometry of proteinase K. Crystallographic study of its complex with a dipeptide chloromethyl ketone inhibitor
    FEBS Lett (3-3-1986) 197, 105-110. PubMed  Europe PubMed  S  I
  80. [YEAR:1-2-1986]Bromme,D., Peters,K., Fink,S. and Fittkau,S.
    Enzyme-substrate interactions in the hydrolysis of peptide substrates by thermitase, subtilisin BPN', and proteinase K
    Arch Biochem Biophys (1-2-1986) 244, 439-446. PubMed  Europe PubMed
  81. Jany,K.D., Lederer,G. and Mayer,B.
    Amino acid sequence of proteinase K from the mold Tritirachium album Limber
    FEBS Lett (1986) 199, 139-144.
    82. 1985
  82. Jany,K.D. and Mayer,B.
    Proteinase K from Tritirachium album Limber. I. Molecular mass and sequence around the active site serine residue
    Biol Chem Hoppe Seyler (1985) 366, 485-492. PubMed  Europe PubMed
    83. 1976
  83. Kraus,E., Kiltz,H.H. and Femfert,U.F.
    The specificity of proteinase K against oxidized insulin B chain
    Hoppe Seylers Z Physiol Chem (1976) 357, 233-237. PubMed  Europe PubMed
    84. 1975
  84. Morihara,K. and Tsuzuki,H.
    Specificity of proteinase K from Tritirachium album Limber for synthetic peptides
    Agric Biol Chem (1975) 39, 1489-1492. DOI  P
    85. 1974
  85. Ebeling,W., Hennrich,N., Klockow,M., Metz,H., Orth,H.D. and Lang,H.
    Proteinase K from Tritirachium album Limber
    Eur J Biochem (1974) 47, 91-97. PubMed  Europe PubMed

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