Literature for peptidase S08.054: endopeptidase K

(Topics flags: S Structure, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Nagel,L., Grossbach,J., Cappelletti,V., Dorig,C., Picotti,P. and Beyer,A.
   Analysis of limited proteolysis-coupled mass spectrometry data
   Mol Cell Proteomics100934-100934. PubMed  Europe PubMed DOI
2. Sun,H., Sun,S., Wang,H., Cheng,K., Zhou,Y., Wang,X., Gao,S., Mo,J., Li,S., Lin,H. and Wang,P.
   Phenylboronic acid-modified carbon dot-proteinase K nanohybrids for enhanced photodynamic therapy against bacterial biofilm infections
   Acta Biomater PubMed  Europe PubMed DOI
3. Zaman,H., Saeed,A., Ismail,H. and Rashid,M.
   Unveiling the cyclopropyl appended acyl thiourea derivatives as antimicrobial, alpha-amylase and proteinase K inhibitors: Design, synthesis, biological evaluation, molecular docking, DFT and ADMET studies
   Arch Biochem Biophys765, 110304-110304. PubMed  Europe PubMed DOI  I
2024
4. Duan,R., Wang,S., Li,Z., Zhang,W., Wu,J., Jiang,Y., Lin,Q., Yuan,P., Yue,X., Yao,Y., Xiao,X., Xiao,Y. and Wang,Z.
   Computer-assisted semi-rational design enhanced the enzymatic activity and protein stability of Proteinase K in calcium-free conditions
   Biochem Biophys Res Commun721, 150109-150109. PubMed  Europe PubMed DOI
5. Gobel,G., Muller,F., Talke,A., Ahnert,U. and Lisdat,F.
   Qualitative and quantitative protease activity tests based on protein degradation in three-dimensional structures
   Bioelectrochemistry160, 108775-108775. PubMed  Europe PubMed DOI
6. Jiang,X., Yeung,D., Liu,Y., Spicer,V., Afshari,H., Lao,Y., Lin,F., Krokhin,O. and Zahedi,R.P.
   Accelerating Proteomics Using Broad Specificity Proteases
   J Proteome Res23, 1360-1369. PubMed  Europe PubMed DOI
7. Yang,Y., Zhang,B. and Zhang,J.
   Probing the binding mode and interactions of proteinase K and glutathione: molecular simulation and experiments
   Soft Matter PubMed  Europe PubMed DOI
8. Zaman,H., Saeed,A., Ismail,H., Anwaar,S., Latif,M., Hashmi,M.Z. and El-Seedi,H.R.
   Novel pyrimidine linked acyl thiourea derivatives as potent alpha-amylase and proteinase K inhibitors: design, synthesis, molecular docking and ADME studies
   RSC Adv14, 33235-33246. PubMed  Europe PubMed DOI  I
2023
9. Liu,K., Zhang,Y., Zhang,W., Liu,L. and Yu,Z.
   A Study on the Interactions of Proteinase K with Myricetin and Myricitrin by Multi-Spectroscopy and Molecular Modeling
   Int J Mol Sci24, PubMed  Europe PubMed DOI  I
10. Yang,J., Chu,N. and Chen,X.
    Preparation of Polyoxometalate-Based Composite by Solidification of Highly Active Cobalt-Containing Polytungstate on Polymeric Ionic Liquid for the Efficient Isolation of Proteinase K
    Molecules28, PubMed  Europe PubMed DOI
2022
11. Li,R., Liu,Z., Jiang,F., Zhao,Y., Yang,G. and Hong,L.
    Enhancement of thermal stability of proteinase K by biocompatible cholinium-based ionic liquids
    Phys Chem Chem Phys24, 13057-13065. PubMed  Europe PubMed DOI
12. Martynowycz,M.W., Clabbers,M.T.B., Hattne,J. and Gonen,T.
    Ab initio phasing macromolecular structures using electron-counted MicroED data
    Nat Methods19, 724-729. PubMed  Europe PubMed DOI
13. Paudyal,S., Sigdel,G., Shah,S.K., Sharma,S.K., Grubb,J.D., Micic,M., Caseli,L. and Leblanc,R.M.
    Interfacial behavior of Proteinase K enzyme at air-saline subphase
    J Colloid Interface Sci616, 701-708. PubMed  Europe PubMed DOI
14. Xu,C., Battig,A., Schartel,B., Siegel,R., Senker,J., von der Forst,I., Unverzagt,C., Agarwal,S., Moglich,A. and Greiner,A.
    Investigation of the Thermal Stability of Proteinase K for the Melt Processing of Poly(l-lactide)
    Biomacromolecules23, 4841-4850. PubMed  Europe PubMed DOI
2021
15. Beklemishev,A.B., Pykhtina,M.B., Kulikov,Y.M., Goryachkovskaya,T.N., Bochkov,D.V., Sergeeva,S.V., Vasileva,A.R., Romanov,V.P., Novikova,D.S. and Peltek,S.E.
    Creation of a recombinant Komagataella phaffii strain, a producer of proteinase K from Tritirachium album
    Vavilovskii Zhurnal Genet Selektsii25, 882-888. PubMed  Europe PubMed DOI
16. Dong,Z., An,L., Lu,M., Tang,M., Chen,H., Huang,X., Hou,Y., Shen,G., Zhang,X., Zhang,Y., Xia,Q. and Zhao,P.
    SPINK7 Recognizes Fungi and Initiates Hemocyte-Mediated Immune Defense Against Fungal Infections
    Front Immunol12, 735497-735497. PubMed  Europe PubMed DOI
17. Zhao,Y., Li,D., Bai,X., Luo,M., Feng,Y., Zhao,Y., Ma,F. and Yang,G.Y.
    Improved thermostability of proteinase K and recognizing the synergistic effect of Rosetta and FoldX approaches
    Protein Eng Des Sel34, PubMed  Europe PubMed DOI
2020
18. Dau,T., Bartolomucci,G. and Rappsilber,J.
    Proteomics Using Protease Alternatives to Trypsin Benefits from Sequential Digestion with Trypsin
    Anal Chem92, 9523-9527. PubMed  Europe PubMed DOI
19. Ren,Y., Luo,H., Huang,H., Hakulinen,N., Wang,Y., Wang,Y., Su,X., Bai,Y., Zhang,J., Yao,B., Wang,G. and Tu,T.
    Improving the catalytic performance of proteinase K from Parengyodontium album for use in feather degradation
    Int J Biol Macromol154, 1586-1595. PubMed  Europe PubMed DOI
20. Richards,L.S., Millan,C., Miao,J., Martynowycz,M.W., Sawaya,M.R., Gonen,T., Borges,R.J., Uson,I. and Rodriguez,J.A.
    Fragment-based determination of a proteinase K structure from MicroED data using ARCIMBOLDO_SHREDDER
    Acta Crystallogr D Struct Biol76, 703-712. PubMed  Europe PubMed DOI
2019
21. Ahmad,M.S., Akbar,Z. and Choudhary,M.I.
    Insight into the binding affinity of thiourea in the calcium binding pocket of proteinase K, through high resolution X-ray crystallography
    Bioorg Chem103443-103443. PubMed  Europe PubMed DOI
2017
22. Du,X., Sang,P., Xia,Y.L., Li,Y., Liang,J., Ai,S.M., Ji,X.L., Fu,Y.X. and Liu,S.Q.
    Comparative thermal unfolding study of psychrophilic and mesophilic subtilisin-like serine proteases by molecular dynamics simulations
    J Biomol Struct Dyn35, 1500-1517. PubMed  Europe PubMed DOI
23. Masuda,T., Suzuki,M., Inoue,S., Song,C., Nakane,T., Nango,E., Tanaka,R., Tono,K., Joti,Y., Kameshima,T., Hatsui,T., Yabashi,M., Mikami,B., Nureki,O., Numata,K., Iwata,S. and Sugahara,M.
    Atomic resolution structure of serine protease proteinase K at ambient temperature
    Sci Rep7, 45604-45604. PubMed  Europe PubMed DOI  S
24. Singh,N. and Bhattacharyya,D.
    Cholesterol and its derivatives reversibly inhibit proteinase K
    J Cell Physiol232, 596-609. PubMed  Europe PubMed DOI
2016
25. Sang,P., Yang,Q., Du,X., Yang,N., Yang,L.Q., Ji,X.L., Fu,Y.X., Meng,Z.H. and Liu,S.Q.
    Effect of the solvent temperatures on dynamics of serine protease proteinase K
    Int J Mol Sci17, 254-254. PubMed  Europe PubMed DOI
26. Yang,H., Zhai,C., Yu,X., Li,Z., Tang,W., Liu,Y., Ma,X., Zhong,X., Li,G., Wu,D. and Ma,L.
    High-level expression of proteinase K from Tritirachium album Limber in Pichia pastoris using multi-copy expression strains
    Protein Expr Purif122, 38-44. PubMed  Europe PubMed DOI  E
2015
27. Kuchler,A., Bleich,J.N., Sebastian,B., Dittrich,P.S. and Walde,P.
    Stable and Simple Immobilization of Proteinase K Inside Glass Tubes and Microfluidic Channels
    ACS Appl Mater Interfaces7, 25970-25980. PubMed  Europe PubMed DOI
28. Silva,C.J., Vazquez-Fernandez,E., Onisko,B. and Requena,J.R.
    Proteinase K and the structure of PrPSc: the good, the bad and the ugly
    Virus Res207, 120-126. PubMed  Europe PubMed DOI
2014
29. Qasim,M.A.
    Specificity of proteinase K at P2 to P3' sub-sites and its comparison to other serine proteases
    Protein Pept Lett21, 164-170. PubMed  Europe PubMed  P
2013
30. Ageitos,J.M., Baker,P.J., Sugahara,M. and Numata,K.
    Proteinase K-catalyzed synthesis of linear and star oligo(l-phenylalanine) conjugates
    Biomacromolecules14, 3635-3642. PubMed  Europe PubMed DOI
2012
31. Kore,A.R. and Shanmugasundaram,M.
    Efficient synthesis of new peptidyl chloromethyl ketones for the application of proteinase K inhibitors
    Synth Commun42, 40-45. DOI  I
32. Petrotchenko,E.V., Serpa,J.J., Hardie,D.B., Berjanskii,M., Suriyamongkol,B.P., Wishart,D.S. and Borchers,C.H.
    Use of proteinase K nonspecific digestion for selective and comprehensive identification of interpeptide cross-links: application to prion proteins
    Mol Cell Proteomics11, M111-M111. PubMed  Europe PubMed DOI
33. Saenger,W.
    Proteinase K
    [ISSN:978-0-12-407742-3]3, 3240-3242. DOI
34. Sommer,C., Hertel,T.C., Schmelzer,C.E. and Pietzsch,M.
    Investigations on the activation of recombinant microbial pro-transglutaminase: in contrast to proteinase K, dispase removes the histidine-tag
    Amino Acids42, 997-1006. PubMed  Europe PubMed DOI
2011
35. Chatake,T., Ishikawa,T., Yanagisawa,Y., Yamada,T., Tanaka,I., Fujiwara,S. and Morimoro,Y.
    High-resolution X-ray study of the effects of deuteration on crystal growth and the crystal structure of proteinase K
    Acta Crystallogr Sect F Struct Biol Cryst Commun67, 1334-1338. PubMed  Europe PubMed DOI  S
36. Liu,S.Q., Tao,Y., Meng,Z.H., Fu,Y.X. and Zhang,K.Q.
    The effect of calciums on molecular motions of proteinase K
    J Mol Model17, 289-300. PubMed  Europe PubMed DOI
37. Panek,J.J., Mazzarello,R., Novic,M. and Jezierska-Mazzarello,A.
    Impact of mercury(II) on proteinase K catalytic center: investigations via classical and Born-Oppenheimer molecular dynamics
    Mol Divers15, 215-226. PubMed  Europe PubMed DOI
38. Tiberti,M. and Papaleo,E.
    Dynamic properties of extremophilic subtilisin-like serine-proteases
    J Struct Biol174, 69-83. PubMed  Europe PubMed DOI  S
2010
39. Kore,A.R. and Shanmugasundaram,M.
    Design, synthesis and inhibitory effect of pentapeptidyl chloromethyl ketones on proteinase K
    Bioorg Med Chem18, 8383-8387. PubMed  Europe PubMed DOI  I
40. Kore,A.R., Shanmugasundaram,M., Charles,I. and Hoang,Q.
    Synthesis and biological evaluation of modified pentapeptides as potent proteinase K inhibitors
    Bioorg Med Chem Lett20, 2750-2754. PubMed  Europe PubMed DOI  I
41. Tao,Y., Rao,Z.H. and Liu,S.Q.
    Insight derived from molecular dynamics simulation into substrate-induced changes in protein motions of proteinase K
    J Biomol Struct Dyn28, 143-158. PubMed  Europe PubMed DOI
2009
42. Gardberg,A.S., Blakeley,M.P. and Myles,D.A.
    A preliminary neutron crystallographic study of proteinase K at pD 6.5
    Acta Crystallograph Sect F Struct Biol Cryst Commun65, 184-187. PubMed  Europe PubMed DOI  S
43. Kore,A.R., Shanmugasundaram,M., Hoang,Q., Kuo,M., Chapman,L.M. and Chen,H.H.
    Synthesis and application of MeOSuc-Ala-Ala-Pro-Phe-CH2Cl as potent proteinase K inhibitor
    Bioorg Med Chem Lett19, 1296-1300. PubMed  Europe PubMed DOI  I
44. Larson,S.B., Day,J.S., Nguyen,C., Cudney,R. and McPherson,A.
    High-resolution structure of proteinase K cocrystallized with digalacturonic acid
    Acta Crystallograph Sect F Struct Biol Cryst Commun65, 192-198. PubMed  Europe PubMed DOI  S
45. Tomar,R., Dubey,V.K. and Jagannadham,M.V.
    Effect of alkyl alcohols on partially unfolded state of proteinase K: differential stability of alpha-helix and beta-sheet rich regions of the enzyme
    Biochimie91, 951-960. PubMed  Europe PubMed DOI
2006
46. Georgieva,D., Genov,N., Voelter,W. and Betzel,C.
    Catalytic efficiencies of alkaline proteinases from microorganisms
    Z Naturforsch C J Biosci61, 445-452.
2004
47. [YEAR:24-12-2004]Georgieva,D., Rypniewski,W., Echner,H., Perbandt,M., Koker,M., Clos,J., Redecke,L., Bredehorst,R., Voelter,W., Genov,N. and Betzel,C.
    Synthetic human prion protein octapeptide repeat binds to the proteinase K active site
    Biochem Biophys Res Commun325, 1406-1411. PubMed  Europe PubMed DOI  S
48. Saenger,W.
    Proteinase K
    [ISSN:0-12-079610-4]2, 1829-1831.  V
2001
49. [YEAR:13-3-2001]Betzel,C., Gourinath,S., Kumar,P., Kaur,P., Perbandt,M., Eschenburg,S. and Singh,T.P.
    Structure of a serine protease proteinase K from Tritirachium album limber at 0.98 A resolution
    Biochemistry40, 3080-3088. PubMed  Europe PubMed DOI  S
50. Gourinath,S., Degenhardt,M., Eschenburg,S., Moore,K., DeLucas,L.J., Betzel,C. and Singh,T.P.
    Mercury induced modifications in the stereochemistry of the active site through Cys-73 in a serine protease - crystal structure of the complex of a partially modified proteinase K with mercury at 1.8 A resolution
    Indian J Biochem Biophys38, 298-302. PubMed  Europe PubMed  S
51. Singh,R.K., Gourinath,S., Sharma,S., Roy,I., Gupta,M.N., Betzel,C., Srinivasan,A. and Singh,T.P.
    Enhancement of enzyme activity through three-phase partitioning: crystal structure of a modified serine proteinase at 1.5 A resolution
    Protein Eng14, 307-313. PubMed  Europe PubMed  S
2000
52. Gupta,M.N., Tyagi,R., Sharma,S., Karthikeyan,S. and Singh,T.P.
    Enhancement of catalytic efficiency of enzymes through exposure to anhydrous organic solvent at 70 degrees C. Three-dimensional structure of a treated serine proteinase at 2.2 A resolution
    Proteins39, 226-234. PubMed  Europe PubMed DOI  S
1998
53. Singh,T.P., Sharma,S., Karthikeyan,S., Betzel,C. and Bhatia,K.L.
    Crystal structure of a complex formed between proteolytically-generated lactoferrin fragment and proteinase K
    Proteins33, 30-38. PubMed  Europe PubMed DOI  S
1996
54. Borhan,B., Hammock,B., Seifert,J. and Wilson,B.W.
    Methyl and phenyl esters and thioesters of carboxylic acids as surrogate substrates for microassay of proteinase K esterase activity
    Anal Bioanal Chem354, 490-492. PubMed  Europe PubMed DOI
55. Saxena,A.K., Singh,T.P., Peters,K., Fittkau,S. and Betzel,C.
    Strategy to design peptide inhibitors: structure of a complex of proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5A resolution
    Protein Sci5, 2453-2458. PubMed  Europe PubMed DOI  S  I
56. Saxena,A.K., Singh,T.P., Peters,K., Fittkau,S., Visanji,M., Wilson,K.S. and Betzel,C.
    Structure of a ternary complex of proteinase K, mercury, and a substrate-analogue hexa-peptide at 2.2 A resolution
    Proteins25, 195-201. PubMed  Europe PubMed DOI  S
1995
57. Ellison,D., Hinton,J., Hubbard,S.J. and Beynon,R.J.
    Limited proteolysis of native proteins: the interaction between avidin and proteinase K
    Protein Sci4, 1337-1345. PubMed  Europe PubMed DOI  P
58. Genov,N., Filippi,B., Dolashka,P., Wilson,K.S. and Betzel,C.
    Stability of subtilisins and related proteinases (subtilases)
    Int J Pept Protein Res45, 391-400. PubMed  Europe PubMed
1994
59. Muller,A., Hinrichs,W., Wolf,W.M. and Saenger,W.
    Crystal structure of calcium-free proteinase K at 1.5-A resolution
    J Biol Chem269, 23108-23111. PubMed  Europe PubMed  S
60. [YEAR:21-3-1994]Pal,G.P., Kavounis,C.A., Jany,K.D. and Tsernoglou,D.
    The three-dimensional structure of the complex of proteinase K with its naturally occurring protein inhibitor, PKI3
    FEBS Lett341, 167-170. PubMed  Europe PubMed DOI  S
1993
61. Betzel,C., Singh,T.P., Visanji,M., Peters,K., Fittkau,S., Saenger,W. and Wilson,K.S.
    Structure of the complex of proteinase K with a substrate analogue hexapeptide inhibitor at 2.2-A resolution
    J Biol Chem268, 15854-15858. PubMed  Europe PubMed  S
62. [YEAR:15-12-1993]Muller,A. and Saenger,W.
    Studies on the inhibitory action of mercury upon proteinase K
    J Biol Chem268, 26150-26154. PubMed  Europe PubMed
63. Sweeney,P.J. and Walker,J.M.
    Proteinase K (EC 3.4.21.14)
    Methods Mol Biol16, 305-311. PubMed  Europe PubMed DOI
1992
64. Bech,L.M., Branner,S., Hastrup,S. and Breddam,K.
    Introduction of a free cysteinyl residue at position 68 in the subtilisin Savinase, based on homology with proteinase K
    FEBS Lett297, 164-166. PubMed  Europe PubMed DOI
65. [YEAR:1-2-1992]Dolashka,P., Dimov,I., Genov,N., Svendsen,I., Wilson,K.S. and Betzel,C.
    Fluorescence properties of native and photooxidised proteinase K: the X-ray model in the region of the two tryptophans
    Biochim Biophys Acta1118, 303-312. PubMed  Europe PubMed DOI  I
1991
66. Samal,B.B., Karan,B., Parker,C. and Stabinsky,Y.
    Isolation and thermal stability studies of two novel serine proteinases from the fungus Tritirachium album Limber
    Enzyme Microb Technol13, 66-70. PubMed  Europe PubMed DOI
67. Wolf,W.M., Bajorath,J., Muller,A., Raghunathan,S., Singh,T.P., Hinrichs,W. and Saenger,W.
    Inhibition of proteinase K by methoxysuccinyl-Ala-Ala-Pro-Ala-chloromethyl ketone. An x-ray study at 2.2-A resolution
    J Biol Chem266, 17695-17699. PubMed  Europe PubMed
1990
68. Betzel,C., Teplyakov,A.V., Harutyunyan,E.H., Saenger,W. and Wilson,K.S.
    Thermitase and proteinase K: a comparison of the refined three-dimensional structures of the native enzymes
    Protein Eng3, 161-172. PubMed  Europe PubMed  S
1989
69. Cerovsky,V. and Martinek,K.
    Amino acids and peptides. Part CCXII. Peptide synthesis catalyzed by native proteinase K in water-miscible organic solvents with low water content
    Collect Czech Chem Commun54, 2027-2041.
70. [YEAR:15-1-1989]Gunkel,F.A. and Gassen,H.G.
    Proteinase K from Tritirachium album Limber. Characterization of the chromosomal gene and expression of the cDNA in Escherichia coli
    Eur J Biochem179, 185-194. PubMed  Europe PubMed
1988
71. [YEAR:15-9-1988]Bajorath,J., Hinrichs,W. and Saenger,W.
    The enzymatic activity of proteinase K is controlled by calcium
    Eur J Biochem176, 441-447. PubMed  Europe PubMed
72. [YEAR:18-5-1988]Bajorath,J., Saenger,W. and Pal,G.P.
    Autolysis and inhibition of proteinase K, a subtilisin-related serine proteinase isolated from the fungus Tritirachium album Limber
    Biochim Biophys Acta954, 176-182. PubMed  Europe PubMed
73. Betzel,C., Pal,G.P. and Saenger,W.
    Synchrotron X-ray data collection and restrained least-squares refinement of the crystal structure of proteinase K at 1.5 A resolution
    Acta Crystallogr B44, 163-172. PubMed  Europe PubMed DOI  S
74. Betzel,C., Bellemann,M., Pal,G.P., Bajorath,J., Saenger,W. and Wilson,K.S.
    X-ray and model-building studies on the specificity of the active site of proteinase K
    Proteins4, 157-164. PubMed  Europe PubMed DOI
75. Betzel,C., Pal,G.P. and Saenger,W.
    Three-dimensional structure of proteinase K at 0.15-nm resolution
    Eur J Biochem178, 155-171. PubMed  Europe PubMed  S
1986
76. [YEAR:3-3-1986]Betzel,C., Pal,G.P., Struck,M., Jany,K.D. and Saenger,W.
    Active-site geometry of proteinase K. Crystallographic study of its complex with a dipeptide chloromethyl ketone inhibitor
    FEBS Lett197, 105-110. PubMed  Europe PubMed  S  I
77. [YEAR:1-2-1986]Bromme,D., Peters,K., Fink,S. and Fittkau,S.
    Enzyme-substrate interactions in the hydrolysis of peptide substrates by thermitase, subtilisin BPN', and proteinase K
    Arch Biochem Biophys244, 439-446. PubMed  Europe PubMed
78. Jany,K.D., Lederer,G. and Mayer,B.
    Amino acid sequence of proteinase K from the mold Tritirachium album Limber
    FEBS Lett199, 139-144.
1985
79. Jany,K.D. and Mayer,B.
    Proteinase K from Tritirachium album Limber. I. Molecular mass and sequence around the active site serine residue
    Biol Chem Hoppe Seyler366, 485-492. PubMed  Europe PubMed
1976
80. Kraus,E., Kiltz,H.H. and Femfert,U.F.
    The specificity of proteinase K against oxidized insulin B chain
    Hoppe Seylers Z Physiol Chem357, 233-237. PubMed  Europe PubMed
1975
81. Morihara,K. and Tsuzuki,H.
    Specificity of proteinase K from Tritirachium album Limber for synthetic peptides
    Agric Biol Chem39, 1489-1492. DOI  P
1974
82. Ebeling,W., Hennrich,N., Klockow,M., Metz,H., Orth,H.D. and Lang,H.
    Proteinase K from Tritirachium album Limber
    Eur J Biochem47, 91-97. PubMed  Europe PubMed