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Literature for peptidase S01.251: kallikrein-related peptidase 4

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, T Target, K Knockout, P Specificity, V Review, M Mutation, R Splicing, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Afratis,N.A., Riley,B.T., Chandler,P.G., Buckle,A.M. and Sagi,I.
    Allosteric Anti-KLK4 Antibody Development for Targeted Anti-Cancer Effects in Ovarian Carcinoma
    J Mol Biol169101-169101. PubMed  Europe PubMed DOI
    2. 2023
  2. Lehto,T.K., Kovanen,R.M., Lintula,S., Malen,A., Sturenberg,C., Erickson,A., Pulkka,O.P., Stenman,U.H., Diamandis,E.P., Rannikko,A., Mirtti,T. and Koistinen,H.
    Prognostic impact of kallikrein-related peptidase transcript levels in prostate cancer
    Int J Cancer153, 867-881. PubMed  Europe PubMed DOI
  3. Li,Y., Zhang,L., Cen,W. and Yuan,Y.
    Association of KLK4 rs2235091 polymorphism with susceptibility to dental caries: a systematic review and meta-analysis
    Front Pediatr11, 1236000-1236000. PubMed  Europe PubMed DOI
    4. 2021
  4. Aydin,E.B., Aydin,M., Yuzer,A., Ince,M., Ocakoglu,K. and Sezginturk,M.K.
    Detection of Kallikrein-Related Peptidase 4 with a Label-free Electrochemical Impedance Biosensor Based on a Zinc(II) Phthalocyanine Tetracarboxylic Acid-Functionalized Disposable Indium Tin Oxide Electrode
    ACS Biomater Sci Eng7, 1192-1201. PubMed  Europe PubMed DOI
  5. Li,M., Srp,J., Mares,M., Wlodawer,A. and Gustchina,A.
    Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
    Acta Crystallogr D Struct Biol77, 1084-1098. PubMed  Europe PubMed DOI
    6. 2020
  6. Gao,J., Li,X., Gao,L., Chen,H., Baras,B.H., Liu,X., Liu,H., Rana,A., Gao,M. and Ruan,J.
    Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikreinrelated peptidase 4 and tight junction proteins in ameloblasts
    Int J Mol Med46, 179-190. PubMed  Europe PubMed DOI
  7. Tse,B.W., Kryza,T., Yeh,M.C., Dong,Y., Sokolowski,K.A., Walpole,C., Dreyer,T., Felber,J., Harris,J., Magdolen,V., Russell,P.J. and Clements,J.A.
    KLK4 Induces Anti-Tumor Effects in Human Xenograft Mouse Models of Orthotopic and Metastatic Prostate Cancer
    Cancers (Basel)12, PubMed  Europe PubMed DOI
  8. Wang,J., Yao,X., Wu,D.L. and Jin,Y.
    Kallikrein-related peptidase 4 promotes migration and invasion of endometrial stromal cells in endometriosis by inducing epithelial-mesenchymal transition
    J Biol Regul Homeost Agents34, 93-100. PubMed  Europe PubMed DOI
    9. 2019
  9. Li,M., Srp,J., Gustchina,A., Dauter,Z., Mares,M. and Wlodawer,A.
    Crystal structures of the complex of a kallikrein inhibitor from Bauhinia bauhinioides with trypsin and modeling of kallikrein complexes
    Acta Crystallogr D Struct Biol75, 56-69. PubMed  Europe PubMed DOI  S
  10. Riley,B.T., Hoke,D.E., McGowan,S. and Buckle,A.M.
    Crystal structure of the inhibitor-free form of the serine protease kallikrein-4
    Acta Crystallogr F Struct Biol Commun75, 543-546. PubMed  Europe PubMed DOI  S
  11. Riley,B.T., Ilyichova,O., de Veer,S.J., Swedberg,J.E., Wilson,E., Hoke,D.E., Harris,J.M. and Buckle,A.M.
    KLK4 Inhibition by cyclic and acyclic peptides: structural and dynamical insights into standard-mechanism protease inhibitors
    Biochemistry58, 2524-2533. PubMed  Europe PubMed DOI
    12. 2018
  12. Loessner,D., Goettig,P., Preis,S., Felber,J., Bronger,H., Clements,J.A., Dorn,J. and Magdolen,V.
    Kallikrein-related peptidases represent attractive therapeutic targets for ovarian cancer
    Expert Opin Ther Targets22, 745-763. PubMed  Europe PubMed DOI  T
  13. Perez,V.A., Mangum,J.E. and Hubbard,M.J.
    Direct evidence that KLK4 is a hydroxyapatite-binding protein
    Biochem Biophys Res Commun495, 1896-1900. PubMed  Europe PubMed DOI
  14. Swedberg,J.E., Ghani,H.A., Harris,J.M., de Veer,S.J. and Craik,D.J.
    Potent, selective, and cell-penetrating inhibitors of kallikrein-related peptidase 4 based on the cyclic peptide MCoTI-II
    ACS Med Chem Lett9, 1258-1262. PubMed  Europe PubMed DOI
    15. 2017
  15. Reid,J.C., Matsika,A., Davies,C.M., He,Y., Broomfield,A., Bennett,N.C., Magdolen,V., Srinivasan,B., Clements,J.A. and Hooper,J.D.
    Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases
    Am J Cancer Res7, 2257-2274. PubMed  Europe PubMed
  16. Smith,C.E.L., Kirkham,J., Day,P.F., Soldani,F., McDerra,E.J., Poulter,J.A., Inglehearn,C.F., Mighell,A.J. and Brookes,S.J.
    A fourth KLK4 mutation is associated with enamel hypomineralisation and structural abnormalities
    Front Physiol8, 333-333. PubMed  Europe PubMed DOI  M
    17. 2016
  17. Fuhrman-Luck,R.A., Stansfield,S.H., Stephens,C.R., Loessner,D. and Clements,J.A.
    Prostate cancer-associated kallikrein-related peptidase 4 activates matrix metalloproteinase-1 and thrombospondin-1
    J Proteome Res15, 2466-2478. PubMed  Europe PubMed DOI  P
  18. Karakosta,T.D., Soosaipillai,A., Diamandis,E.P., Batruch,I. and Drabovich,A.P.
    Quantification of human kallikrein-related peptidases in biological fluids by multiplatform targeted mass spectrometry assays
    Mol Cell Proteomics15, 2863-2876. PubMed  Europe PubMed DOI  A
  19. Riley,B.T., Ilyichova,O., Costa,M.G., Porebski,B.T., de Veer,S.J., Swedberg,J.E., Kass,I., Harris,J.M., Hoke,D.E. and Buckle,A.M.
    Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
    Sci Rep6, 35385-35385. PubMed  Europe PubMed DOI  S
    20. 2015
  20. Lisle,J.E., Mertens-Walker,I., Stephens,C.R., Stansfield,S.H., Clements,J.A., Herington,A.C. and Stephenson,S.A.
    Murine, but not human, ephrin-B2 can be efficiently cleaved by the serine protease kallikrein-4: implications for xenograft models of human prostate cancer
    Exp Cell Res333, 136-146. PubMed  Europe PubMed DOI
    21. 2014
  21. Bartlett,J.D. and Simmer,J.P.
    Kallikrein-related peptidase-4 (KLK4): role in enamel formation and revelations from ablated mice
    Front Physiol5, 240-240. PubMed  Europe PubMed DOI
  22. Kawasaki,K., Hu,J.C. and Simmer,J.P.
    Evolution of Klk4 and enamel maturation in eutherians
    Biol Chem395, 1003-1013. PubMed  Europe PubMed DOI
    23. 2013
  23. Jin,Y., Qu,S., Tesikova,M., Wang,L., Kristian,A., Maelandsmo,G.M., Kong,H., Zhang,T., Jeronimo,C., Teixeira,M.R., Yuca,E., Tekedereli,I., Gorgulu,K., Alpay,N., Sood,A.K., Lopez-Berestein,G., Danielsen,H.E., Ozpolat,B. and Saatcioglu,F.
    Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer
    Proc Natl Acad Sci U S A110, E2572-E2581. PubMed  Europe PubMed DOI
  24. Lundwall,A.
    Old genes and new genes: The evolution of the kallikrein locus
    Thromb Haemost110, 469-475. PubMed  Europe PubMed DOI  V
  25. Wang,S.K., Hu,Y., Simmer,J.P., Seymen,F., Estrella,N.M.R.P., Pal,S., Reid,B.M., Yildirim,M., Bayram,M., Bartlett,J.D. and Hu,J.C.C.
    Novel KLK4 and MMP20 mutations discovered by whole-exome sequencing
    J Dent Res92, 266-271. PubMed  Europe PubMed DOI  M
    26. 2012
  26. Simmer,J.P.
    Kallikrein-related peptidase 4
    [ISSN:978-0-12-407742-3]3, 2768-2772. DOI
    27. 2011
  27. Hu,Y., Hu,J.C., Smith,C.E., Bartlett,J.D. and Simmer,J.P.
    Kallikrein-related peptidase 4, matrix metalloproteinase 20, and the maturation of murine and porcine enamel
    Eur J Oral Sci119 Suppl 1, 217-225. PubMed  Europe PubMed DOI
  28. Simmer,J.P., Hu,Y., Richardson,A.S., Bartlett,J.D. and Hu,J.C.
    Why does enamel in Klk4-null mice break above the dentino-enamel junction?
    Cells Tissues Organs194, 211-215. PubMed  Europe PubMed DOI  K
  29. Smith,C.E., Richardson,A.S., Hu,Y., Bartlett,J.D., Hu,J.C. and Simmer,J.P.
    Effect of kallikrein 4 loss on enamel mineralization: comparison with mice lacking matrix metalloproteinase 20
    J Biol Chem286, 18149-18160. PubMed  Europe PubMed DOI
  30. Yamakoshi,Y., Richardson,A.S., Nunez,S.M., Yamakoshi,F., Milkovich,R.N., Hu,J.C., Bartlett,J.D. and Simmer,J.P.
    Enamel proteins and proteases in Mmp20 and Klk4 null and double-null mice
    Eur J Oral Sci119 Suppl 1, 206-216. PubMed  Europe PubMed DOI  K
  31. Yamakoshi,Y., Yamakoshi,F., Hu,J.C. and Simmer,J.P.
    Characterization of kallikrein-related peptidase 4 glycosylations
    Eur J Oral Sci119 Suppl 1, 234-240. PubMed  Europe PubMed DOI
    32. 2010
  32. Angelopoulou,K. and Karagiannis,G.S.
    Structural characterization and expression of five novel canine kallikrein-related peptidases in mammary cancer
    Mamm Genome21, 516-524. PubMed  Europe PubMed DOI
  33. Gratio,V., Beaufort,N., Seiz,L., Maier,J., Virca,G.D., Debela,M., Grebenchtchikov,N., Magdolen,V. and Darmoul,D.
    Kallikrein-related peptidase 4: a new activator of the aberrantly expressed protease-activated receptor 1 in colon cancer cells
    Am J Pathol176, 1452-1461. PubMed  Europe PubMed DOI
  34. Wang,W., Mize,G.J., Zhang,X. and Takayama,T.K.
    Kallikrein-related peptidase-4 initiates tumor-stroma interactions in prostate cancer through protease-activated receptor-1
    Int J Cancer126, 599-610. PubMed  Europe PubMed DOI
    35. 2009
  35. Nagano,T., Kakegawa,A., Yamakoshi,Y., Tsuchiya,S., Hu,J.C., Gomi,K., Arai,T., Bartlett,J.D. and Simmer,J.P.
    Mmp-20 and Klk4 cleavage site preferences for amelogenin sequences
    J Dent Res88, 823-828. PubMed  Europe PubMed DOI  P
  36. Swedberg,J.E., Nigon,L.V., Reid,J.C., de Veer,S.J., Walpole,C.M., Stephens,C.R., Walsh,T.P., Takayama,T.K., Hooper,J.D., Clements,J.A., Buckle,A.M. and Harris,J.M.
    Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4
    Chem Biol16, 633-643. PubMed  Europe PubMed DOI  I
  37. Tye,C.E., Pham,C.T., Simmer,J.P. and Bartlett,J.D.
    DPPI may activate KLK4 during enamel formation
    J Dent Res88, 323-327. PubMed  Europe PubMed DOI
    38. 2008
  38. Clements,J.A.
    Reflections on the tissue kallikrein and kallikrein-related peptidase family - from mice to men - what have we learnt in the last two decades?
    Biol Chem389, 1447-1454. PubMed  Europe PubMed DOI  V
  39. Debela,M., Beaufort,N., Magdolen,V., Schechter,N.M., Craik,C.S., Schmitt,M., Bode,W. and Goettig,P.
    Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7
    Biol Chem389, 623-632. PubMed  Europe PubMed DOI  P  S
  40. Lu,Y., Papagerakis,P., Yamakoshi,Y., Hu,J.C., Bartlett,J.D. and Simmer,J.P.
    Functions of KLK4 and MMP-20 in dental enamel formation
    Biol Chem389, 695-700. PubMed  Europe PubMed DOI
  41. Mukai,S., Fukushima,T., Naka,D., Tanaka,H., Osada,Y. and Kataoka,H.
    Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases
    FEBS J275, 1003-1017. PubMed  Europe PubMed DOI
  42. Ramsay,A.J., Dong,Y., Hunt,M.L., Linn,M., Samaratunga,H., Clements,J.A. and Hooper,J.D.
    Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression
    J Biol Chem283, 12293-12304. PubMed  Europe PubMed DOI
    43. 2007
  43. Borgono,C.A., Gavigan,J.A., Alves,J., Bowles,B., Harris,J.L., Sotiropoulou,G. and Diamandis,E.P.
    Defining the extended substrate specificity of kallikrein 1-related peptidases
    Biol Chem388, 1215-1225. PubMed  Europe PubMed DOI  P
  44. Fernando,S.C., Najar,F.Z., Guo,X., Zhou,L., Fu,Y., Geisert,R.D., Roe,B.A. and DeSilva,U.
    Porcine kallikrein gene family: genomic structure, mapping, and differential expression analysis
    Genomics89, 429-438. PubMed  Europe PubMed DOI
  45. Klokk,T.I., Kilander,A., Xi,Z., Waehre,H., Risberg,B., Danielsen,H.E. and Saatcioglu,F.
    Kallikrein 4 is a proliferative factor that is overexpressed in prostate cancer
    Cancer Res67, 5221-5230. PubMed  Europe PubMed DOI
  46. Lawrence,M.G., Veveris-Lowe,T.L., Whitbread,A.K., Nicol,D.L. and Clements,J.A.
    Epithelial-mesenchymal transition in prostate cancer and the potential role of kallikrein serine proteases
    Cells Tissues Organs185, 111-115. PubMed  Europe PubMed DOI
  47. Yoon,H., Laxmikanthan,G., Lee,J., Blaber,S.I., Rodriguez,A., Kogot,J.M., Scarisbrick,I.A. and Blaber,M.
    Activation profiles and regulatory cascades of the human kallikrein-related peptidases
    J Biol Chem282, 31852-31864. PubMed  Europe PubMed DOI  V
    48. 2006
  48. Beaufort,N., Debela,M., Creutzburg,S., Kellermann,J., Bode,W., Schmitt,M., Pidard,D. and Magdolen,V.
    Interplay of human tissue kallikrein 4 (hK4) with the plasminogen activation system: hK4 regulates the structure and functions of the urokinase-type plasminogen activator receptor (uPAR)
    Biol Chem387, 217-222. PubMed  Europe PubMed DOI
  49. [YEAR:1-6-2006]Debela,M., Magdolen,V., Schechter,N., Valachova,M., Lottspeich,F., Craik,C.S., Choe,Y., Bode,W. and Goettig,P.
    Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences
    J Biol Chem281, 25678-25688. PubMed  Europe PubMed DOI  P
  50. [YEAR:3-8-2006]Debela,M., Magdolen,V., Grimminger,V., Sommerhoff,C., Messerschmidt,A., Huber,R., Friedrich,R., Bode,W. and Goettig,P.
    Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site
    J Mol Biol362, 1094-1107. PubMed  Europe PubMed DOI  S
  51. Obiezu,C.V., Michael,I.P., Levesque,M.A. and Diamandis,E.P.
    Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins
    Biol Chem387, 749-759. PubMed  Europe PubMed DOI
  52. Prezas,P., Arlt,M.J., Viktorov,P., Soosaipillai,A., Holzscheiter,L., Schmitt,M., Talieri,M., Diamandis,E.P., Kruger,A. and Magdolen,V.
    Overexpression of the human tissue kallikrein genes KLK4, 5, 6, and 7 increases the malignant phenotype of ovarian cancer cells
    Biol Chem387, 807-811. PubMed  Europe PubMed DOI
  53. Wright,J.T., Daly,B., Simmons,D., Hong,S., Hart,S.P., Hart,T.C., Atsawasuwan,P. and Yamauchi,M.
    Human enamel phenotype associated with amelogenesis imperfecta and a kallikrein-4 (g.2142G>A) proteinase mutation
    Eur J Oral Sci114 Suppl 1, 13-17. PubMed  Europe PubMed DOI
  54. Yamakoshi,Y., Hu,J.C., Fukae,M., Yamakoshi,F. and Simmer,J.P.
    How do enamelysin and kallikrein 4 process the 32-kDa enamelin?
    Eur J Oral Sci114 Suppl 1, 45-51. PubMed  Europe PubMed DOI
    55. 2005
  55. Davidson,B., Xi,Z., Klokk,T.I., Trope,C.G., Dorum,A., Scheistroen,M. and Saatcioglu,F.
    Kallikrein 4 expression is up-regulated in epithelial ovarian carcinoma cells in effusions
    Am J Clin Pathol123, 360-368. PubMed  Europe PubMed DOI
  56. [YEAR:25-5-2005]Kurlender,L., Borgono,C., Michael,I.P., Obiezu,C., Elliott,M.B., Yousef,G.M. and Diamandis,E.P.
    A survey of alternative transcripts of human tissue kallikrein genes
    Biochim Biophys Acta1755, 1-14. PubMed  Europe PubMed DOI  R
  57. [YEAR:22-4-2005]Matsumura,M., Bhatt,A.S., Andress,D., Clegg,N., Takayama,T.K., Craik,C.S. and Nelson,P.S.
    Substrates of the prostate-specific serine protease prostase/KLK4 defined by positional-scanning peptide libraries
    Prostate62, 1-13. PubMed  Europe PubMed DOI  P
  58. [YEAR:13-1-2005]Michael,I.P., Kurlender,L., Memari,N., Yousef,G.M., Du,D., Grass,L., Stephan,C., Jung,K. and Diamandis,E.P.
    Intron retention: a common splicing event within the human kallikrein gene family
    Clin Chem51, 506-515. PubMed  Europe PubMed DOI  R
  59. [YEAR:16-6-2005]Obiezu,C.V., Shan,S.J., Soosaipillai,A., Luo,L.Y., Grass,L., Sotiropoulou,G., Petraki,C.D., Papanastasiou,P.A., Levesque,M.A. and Diamandis,E.P.
    Human kallikrein 4: quantitative study in tissues and evidence for its secretion into biological fluids
    Clin Chem51, 1432-1442. PubMed  Europe PubMed DOI
  60. Veveris-Lowe,T.L., Lawrence,M.G., Collard,R.L., Bui,L., Herington,A.C., Nicol,D.L. and Clements,J.A.
    Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer cells
    Endocr Relat Cancer12, 631-643. PubMed  Europe PubMed DOI
    61. 2004
  61. Clements,J.A., Hooper,J.D., Odorico,D.M. and Dong,Y.
    The tissue kallikrein gene cluster
    [ISSN:0-12-079610-4]2, 1569-1577.  V
  62. Hart,P.S., Hart,T.C., Michalec,M.D., Ryu,O.H., Simmons,D., Hong,S. and Wright,J.T.
    Mutation in kallikrein 4 causes autosomal recessive hypomaturation amelogenesis imperfecta
    J Med Genet41, 545-549. PubMed  Europe PubMed
  63. [YEAR:15-11-2004]Simmer,J.P. and Bartlett,J.D.
    Kallikrein 4 is a secreted protein
    Cancer Res64, 8481-8482. PubMed  Europe PubMed DOI
  64. Simmer,J.P.
    Prostase
    [ISSN:0-12-079610-4]2, 1612-1614.  V
  65. [YEAR:1-4-2004]Xi,Z., Klokk,T.I., Korkmaz,K., Kurys,P., Elbi,C., Risberg,B., Danielsen,H., Loda,M. and Saatcioglu,F.
    Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer
    Cancer Res64, 2365-2370. PubMed  Europe PubMed DOI
  66. Xi,Z., Kaern,J., Davidson,B., Klokk,T.I., Risberg,B., Trope,C. and Saatcioglu,F.
    Kallikrein 4 is associated with paclitaxel resistance in ovarian cancer
    Gynecol Oncol94, 80-85. PubMed  Europe PubMed DOI
    67. 2003
  67. Harvey,T.J., Dong,Y., Bui,L., Jarrott,R., Walsh,T. and Clements,J.A.
    Production and characterization of antipeptide kallikrein 4 antibodies. Use of computer modeling to design peptides specific to kallikrein 4
    Methods Mol Med81, 241-254. PubMed  Europe PubMed DOI
    68. 2002
  68. [YEAR:1-7-2002]Hural,J.A., Friedman,R.S., McNabb,A., Steen,S.S., Henderson,R.A. and Kalos,M.
    Identification of naturally processed CD4 T cell epitopes from the prostate-specific antigen kallikrein 4 using peptide-based in vitro stimulation
    J Immunol169, 557-565. PubMed  Europe PubMed
  69. Ryu,O., Hu,J.C., Yamakoshi,Y., Villemain,J.L., Cao,X., Zhang,C., Bartlett,J.D. and Simmer,J.P.
    Porcine kallikrein-4 activation, glycosylation, activity, and expression in prokaryotic and eukaryotic hosts
    Eur J Oral Sci110, 358-365. PubMed  Europe PubMed
  70. Simmer,J.P. and Hu,J.C.
    Expression, structure, and function of enamel proteinases
    Connect Tissue Res43, 441-449. PubMed  Europe PubMed
    71. 2001
  71. Clements,J., Hooper,J., Dong,Y. and Harvey,T.
    The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions
    Biol Chem382, 5-14. PubMed  Europe PubMed DOI  V
  72. Dong,Y., Kaushal,A., Bui,L., Chu,S., Fuller,P.J., Nicklin,J., Samaratunga,H. and Clements,J.A.
    Human kallikrein 4 (KLK4) is highly expressed in serous ovarian carcinomas
    Clin Cancer Res7, 2363-2371. PubMed  Europe PubMed
  73. Korkmaz,K.S., Korkmaz,C.G., Pretlow,T.G. and Saatcioglu,F.
    Distinctly different gene structure of KLK4/KLK-L1/prostase/ARM1 compared with other members of the Kallikrein family: Intracellular localization, alternative cDNA forms, and regulation by multiple hormones
    DNA Cell Biol20, 435-445. PubMed  Europe PubMed DOI  R
  74. Myers,S.A. and Clements,J.A.
    Kallikrein 4 (KLK4), a new member of the human kallikrein gene family is up-regulated by estrogen and progesterone in the human endometrial cancer cell line, KLE
    J Clin Endocrinol Metab86, 2323-2326. PubMed  Europe PubMed DOI
  75. Obiezu,C.V., Scorilas,A., Katsaros,D., Massobrio,M., Yousef,G.M., Fracchioli,S., Rigault de la Longrais,I.A., Arisio,R. and Diamandis,E.P.
    Higher human kallikrein gene 4 (KLK4) expression indicates poor prognosis of ovarian cancer patients
    Clin Cancer Res7, 2380-2386. PubMed  Europe PubMed
  76. [YEAR:18-12-2001]Takayama,T.K., McMullen,B.A., Nelson,P.S., Matsumura,M. and Fujikawa,K.
    Characterization of hK4 (prostase), a prostate-specific serine protease: Activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and degradation of prostatic acid phosphatase
    Biochemistry40, 15341-15348. PubMed  Europe PubMed DOI
    77. 2000
  77. Hu,J.C.C., Ryu,O.H., Chen,J.J., Uchida,T., Wakida,K., Murakami,C., Jiang,H., Qian,Q., Zhang,C., Ottmers,V., Bartlett,J.D. and Simmer,J.P.
    Localization of EMSP1 expression during tooth formation and cloning of mouse cDNA
    J Dent Res79, 70-76. PubMed  Europe PubMed
  78. [YEAR:13-6-2000]Hu,J.C.C., Zhang,C.H., Sun,X.L., Yang,Y., Cao,X.H., Ryu,O. and Simmer,J.P.
    Characterization of the mouse and human PRSS17 genes, their relationship to other serine proteases, and the expression of PRSS17 in developing mouse incisors
    Gene251, 1-8. PubMed  Europe PubMed DOI
    79. 1999
  79. Bartlett,J.D. and Simmer,J.P.
    Proteinases in developing dental enamel
    Crit Rev Oral Biol Med10, 425-441. PubMed  Europe PubMed
  80. DuPont,B.R., Hu,C.C., Reveles,X. and Simmer,J.P.
    Assignment of serine protease 17 (PRSS17) to human chromosome bands 19q13.3 - >q13.4 by in situ hybridization
    Cytogenet Cell Genet86, 212-213. PubMed  Europe PubMed
  81. [YEAR:16-3-1999]Nelson,P.S., Gan,L., Ferguson,C., Moss,P., Gelinas,R., Hood,L. and Wang,K.
    Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression
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